Detailed information for compound 672597

Basic information

Technical information
  • TDR Targets ID: 672597
  • Name: 1-[2-[(3-methoxyphenyl)-phenylsulfonylamino]a cetyl]piperidine-4-carboxamide
  • MW: 431.505 | Formula: C21H25N3O5S
  • H donors: 1 H acceptors: 4 LogP: 1.5 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cccc(c1)N(S(=O)(=O)c1ccccc1)CC(=O)N1CCC(CC1)C(=O)N
  • InChi: 1S/C21H25N3O5S/c1-29-18-7-5-6-17(14-18)24(30(27,28)19-8-3-2-4-9-19)15-20(25)23-12-10-16(11-13-23)21(22)26/h2-9,14,16H,10-13,15H2,1H3,(H2,22,26)
  • InChiKey: MSGJOPLAXKDUND-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-[2-[(3-methoxyphenyl)-phenylsulfonyl-amino]acetyl]piperidine-4-carboxamide
  • 1-[2-[(3-methoxyphenyl)-phenylsulfonylamino]-1-oxoethyl]-4-piperidinecarboxamide
  • 1-[2-[(3-methoxyphenyl)-phenylsulfonyl-amino]acetyl]isonipecotamide
  • 1-[2-[(3-methoxyphenyl)-phenylsulfonyl-amino]ethanoyl]piperidine-4-carboxamide
  • ZINC00785267
  • STK014541
  • 1-{2-[Benzenesulfonyl-(3-methoxy-phenyl)-amino]-acetyl}-piperidine-4-carboxylic
  • BAS 04920470

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.017 0.0059
Echinococcus granulosus dna polymerase eta 0.0205 0.256 0.3691
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3761 0.3653
Brugia malayi mbt repeat family protein 0.0049 0.0283 0.0132
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0999 0.1253
Brugia malayi ImpB/MucB/SamB family protein 0.0129 0.1446 0.149
Loa Loa (eye worm) hypothetical protein 0.0073 0.0626 0.0716
Trichomonas vaginalis set domain proteins, putative 0.0713 1 1
Echinococcus multilocularis protein patched 0.0041 0.017 0.0245
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.017 0.0245
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0129 0.1446 0.2085
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0903 0.1112
Trypanosoma cruzi DNA polymerase eta, putative 0.0116 0.1262 0.2989
Echinococcus multilocularis cpg binding protein 0.0091 0.089 0.1283
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0626 0.0331
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0283 0.0409
Plasmodium vivax deoxyuridine 5'-triphosphate nucleotidohydrolase, putative 0.017 0.2058 1
Giardia lamblia DINP protein human, muc B family 0.0135 0.154 0.3854
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0056 0.0383 0.0552
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0195
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3761 0.3653
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0626 0.0704
Schistosoma mansoni DNA polymerase eta 0.0205 0.256 0.3554
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0626 0.1283
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0626 0.0902
Mycobacterium ulcerans glutaminase 0.0266 0.3466 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0095 0.0956 0.2169
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0135 0.154 0.3737
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0116 0.1262 0.5831
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0283 0.0409
Mycobacterium ulcerans DNA polymerase IV 0.0154 0.1826 0.5058
Plasmodium falciparum deoxyuridine 5'-triphosphate nucleotidohydrolase 0.017 0.2058 1
Trichomonas vaginalis deoxyuridine 5'-triphosphate nucleotidohydrolase, putative 0.017 0.2058 0.1921
Brugia malayi polk-prov protein 0.0066 0.0527 0.0417
Loa Loa (eye worm) hypothetical protein 0.0091 0.0903 0.1033
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.017 0.0059
Onchocerca volvulus 0.0091 0.0903 0.0637
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0091 0.0903 0.1301
Echinococcus granulosus cpg binding protein 0.0091 0.089 0.1283
Brugia malayi beta-lactamase family protein 0.0073 0.0626 0.0532
Entamoeba histolytica deoxycytidyl transferase, putative 0.0129 0.1446 0.3052
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0626 0.0704
Echinococcus multilocularis protein dispatched 1 0.0047 0.0256 0.0369
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0129 0.1446 0.1913
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0626 0.1283
Trichomonas vaginalis glutaminase, putative 0.0266 0.3466 0.3353
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0129 0.1446 0.1655
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.3761 1
Mycobacterium tuberculosis Conserved protein 0.0073 0.0626 0.0331
Toxoplasma gondii hypothetical protein 0.0047 0.0259 0.0581
Mycobacterium tuberculosis Conserved protein 0.0073 0.0626 0.0331
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.1604 0.3907
Trypanosoma brucei DNA polymerase IV, putative 0.0154 0.1826 0.4502
Trichomonas vaginalis DNA polymerase eta, putative 0.0154 0.1826 0.1685
Brugia malayi mbt repeat family protein 0.0049 0.0283 0.0132
Brugia malayi Pre-SET motif family protein 0.0626 0.8736 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0095 0.0956 0.2169
Brugia malayi beta-lactamase 0.0073 0.0626 0.0532
Echinococcus granulosus dna polymerase kappa 0.0154 0.1826 0.2632
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.017 0.0059
Mycobacterium leprae Probable lipase LipE 0.0073 0.0626 0.1657
Onchocerca volvulus 0.0086 0.0818 0.055
Trypanosoma brucei DNA polymerase kappa, putative 0.0154 0.1826 0.4502
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0626 0.0331
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor, putative 0.017 0.2058 0.4889
Echinococcus multilocularis muscleblind protein 0.0152 0.1785 0.2574
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.1583 0.2282
Mycobacterium leprae conserved hypothetical protein 0.0073 0.0626 0.1657
Leishmania major hypothetical protein, conserved 0.0073 0.0626 0.1283
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0294 0.3875 1
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0626 0.0331
Onchocerca volvulus 0.0073 0.0626 0.0352
Brugia malayi ImpB/MucB/SamB family protein 0.0205 0.256 0.279
Trichomonas vaginalis esterase, putative 0.0073 0.0626 0.0464
Entamoeba histolytica hypothetical protein 0.0111 0.1192 0.2289
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0903 0.1112
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0977 0.1408
Trypanosoma brucei DNA polymerase kappa, putative 0.0095 0.0956 0.2169
Loa Loa (eye worm) glutaminase 2 0.0266 0.3466 0.3967
Trypanosoma cruzi DNA polymerase kappa, putative 0.0154 0.1826 0.4502
Wolbachia endosymbiont of Brugia malayi dUTPase 0.017 0.2058 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0154 0.1826 0.4502
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.017 0.2058 0.4889
Loa Loa (eye worm) hypothetical protein 0.0097 0.0977 0.1118
Loa Loa (eye worm) hypothetical protein 0.0056 0.0383 0.0439
Echinococcus multilocularis dna polymerase kappa 0.0154 0.1826 0.2632
Echinococcus granulosus Protein patched homolog 1 0.0041 0.017 0.0245
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0626 0.0464
Loa Loa (eye worm) hypothetical protein 0.0051 0.0306 0.0351
Trypanosoma brucei DNA polymerase kappa, putative 0.0135 0.154 0.3737
Brugia malayi glutaminase DH11.1 0.0266 0.3466 0.3847
Schistosoma mansoni hypothetical protein 0.0303 0.3995 0.5667
Trypanosoma cruzi DNA polymerase eta, putative 0.0205 0.256 0.6473
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0977 0.0942
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0626 0.0331
Loa Loa (eye worm) hypothetical protein 0.0073 0.0626 0.0716
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3761 0.3653
Echinococcus granulosus geminin 0.0503 0.6936 1
Echinococcus multilocularis dna polymerase eta 0.0205 0.256 0.3691
Schistosoma mansoni glutaminase 0.0266 0.3466 0.4888
Toxoplasma gondii ABC1 family protein 0.0073 0.0626 0.2502
Loa Loa (eye worm) hypothetical protein 0.0073 0.0626 0.0716
Onchocerca volvulus 0.0073 0.0626 0.0352
Schistosoma mansoni cpg binding protein 0.0091 0.089 0.1093
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0626 0.0716
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0129 0.1446 0.2085
Brugia malayi Muscleblind-like protein 0.0152 0.1785 0.1886
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.1614 0.2
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0626 0.0464
Entamoeba histolytica hypothetical protein 0.017 0.2058 0.4889
Brugia malayi dUTP diphosphatase 0.017 0.2058 0.2204
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0056 0.0383 0.0249
Schistosoma mansoni cpg binding protein 0.0091 0.089 0.1093
Loa Loa (eye worm) beta-lactamase 0.0073 0.0626 0.0716
Trypanosoma brucei DNA polymerase kappa, putative 0.0154 0.1826 0.4502
Echinococcus multilocularis geminin 0.0503 0.6936 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0154 0.1826 0.4502
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0283 0.02
Loa Loa (eye worm) hypothetical protein 0.0073 0.0626 0.0716
Leishmania major mitochondrial DNA polymerase beta 0.0294 0.3875 1
Trypanosoma brucei unspecified product 0.0089 0.0862 0.1916
Echinococcus multilocularis dnaJ subfamily B 0.0399 0.5402 0.7789
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.3761 1
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0626 0.2502
Mycobacterium ulcerans DNA polymerase IV 0.0154 0.1826 0.5058
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0626 0.1441
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.017 0.0195
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0135 0.154 0.1876
Loa Loa (eye worm) hypothetical protein 0.0073 0.0626 0.0716
Giardia lamblia Fructose-bisphosphate aldolase 0.0287 0.3761 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0283 0.0324
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3761 0.3653
Mycobacterium ulcerans beta-lactamase 0.0073 0.0626 0.1441
Mycobacterium tuberculosis Conserved protein 0.0073 0.0626 0.0331
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.017 0.2058 0.4889
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor, putative 0.017 0.2058 0.4889
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0626 0.0464
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0139 0.1604 0.3907
Trypanosoma brucei DNA polymerase kappa, putative 0.0154 0.1826 0.4502
Trypanosoma brucei unspecified product 0.0089 0.0862 0.1916
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0283 0.02
Loa Loa (eye worm) hypothetical protein 0.0205 0.256 0.2931
Trypanosoma brucei DNA polymerase IV, putative 0.0148 0.1732 0.425
Trypanosoma cruzi DNA polymerase kappa, putative 0.0154 0.1826 0.4502
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0903 0.1112
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0977 0.1408
Trypanosoma brucei DNA polymerase eta, putative 0.0205 0.256 0.6473
Mycobacterium ulcerans hypothetical protein 0.0073 0.0626 0.1441
Trypanosoma brucei DNA polymerase IV, putative 0.0154 0.1826 0.4502
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.017 0.2058 0.4889
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0626 0.1441
Schistosoma mansoni terminal deoxycytidyl transferase 0.0129 0.1446 0.1913
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.1604 0.3907
Loa Loa (eye worm) MBCTL1 0.0056 0.0383 0.0439
Trypanosoma brucei DNA polymerase kappa, putative 0.0154 0.1826 0.4502
Echinococcus granulosus histone lysine methyltransferase setb 0.0091 0.0903 0.1301
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0091 0.0903 0.1112
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.1583 0.2282
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0056 0.0383 0.0552
Entamoeba histolytica hypothetical protein 0.0111 0.1192 0.2289
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0626 0.0331
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0626 0.0464
Brugia malayi Pre-SET motif family protein 0.0091 0.0903 0.0855
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0626 0.0331
Chlamydia trachomatis deoxyuridine 5'-triphosphate nucleotidohydrolase 0.017 0.2058 1
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0626 0.0464
Loa Loa (eye worm) glutaminase 0.0266 0.3466 0.3967
Brugia malayi CXXC zinc finger family protein 0.0086 0.0818 0.0757
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0086 0.0827 0.1192
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0977 0.1642
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0463 0.6351 1
Loa Loa (eye worm) hypothetical protein 0.0152 0.1785 0.2043
Echinococcus multilocularis muscleblind protein 1 0.0152 0.1785 0.2574
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0046 0.0242 0.0493
Schistosoma mansoni hypothetical protein 0.0503 0.6936 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0185 0.2273 0.3131
Echinococcus granulosus histone acetyltransferase MYST2 0.0056 0.0383 0.0552
Echinococcus granulosus dnaJ subfamily B 0.0399 0.5402 0.7789
Toxoplasma gondii histone lysine methyltransferase SET1 0.0166 0.1989 0.9637
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0197 0.2455 0.354
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0283 0.02
Schistosoma mansoni patched 1 0.0041 0.017 0.0033
Trypanosoma brucei unspecified product 0.0148 0.1732 0.425
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0197 0.2455 0.354
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0283 0.0409
Mycobacterium ulcerans hypothetical protein 0.0155 0.1834 0.5083
Trypanosoma brucei DNA polymerase kappa, putative 0.0154 0.1826 0.4502
Trypanosoma brucei DNA polymerase kappa, putative 0.0154 0.1826 0.4502
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.1614 1
Schistosoma mansoni hypothetical protein 0.0399 0.5402 0.774
Trypanosoma brucei DNA polymerase kappa, putative 0.0154 0.1826 0.4502
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0626 0.1283
Mycobacterium ulcerans deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0059 0.043 0.0849
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0154 0.1826 0.1685
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.017 0.2058 0.4889
Leishmania major DNA polymerase eta, putative 0.0205 0.256 0.6473
Loa Loa (eye worm) CXXC zinc finger family protein 0.0086 0.0818 0.0937
Echinococcus multilocularis expressed conserved protein 0.0091 0.0891 0.1285
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0626 0.0902
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.3875 1
Leishmania major DNA polymerase kappa, putative 0.0135 0.154 0.3737
Trypanosoma brucei DNA polymerase kappa, putative 0.0154 0.1826 0.4502
Leishmania major DNA polymerase eta, putative 0.0116 0.1262 0.2989
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3761 0.3653
Loa Loa (eye worm) hypothetical protein 0.0066 0.0527 0.0604
Schistosoma mansoni deoxyuridine 5'-triphosphate nucleotidohydrolase 0.017 0.2058 0.2814
Mycobacterium tuberculosis Conserved hypothetical protein 0.0129 0.1446 0.1717
Echinococcus multilocularis histone acetyltransferase MYST2 0.0056 0.0383 0.0552
Schistosoma mansoni myelin transcription factor 1 myt1 0.0056 0.0383 0.0347
Echinococcus granulosus dUTP pyrophosphatase 0.017 0.2058 0.2967
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0283 0.0409
Schistosoma mansoni cpg binding protein 0.0086 0.0818 0.0988
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3761 0.3653
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0283 0.0324
Treponema pallidum fructose-bisphosphate aldolase 0.0287 0.3761 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0626 0.0532
Trypanosoma cruzi DNA polymerase kappa, putative 0.0154 0.1826 0.4502
Loa Loa (eye worm) hypothetical protein 0.0152 0.1785 0.2043
Mycobacterium ulcerans deoxycytidine triphosphate deaminase 0.0059 0.043 0.0849
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3761 0.3653
Brugia malayi beta-lactamase family protein 0.0073 0.0626 0.0532
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.017 0.0245
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.0903 0.1301
Onchocerca volvulus 0.0073 0.0626 0.0352
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.1614 0.4419
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.3875 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0626 0.0331
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.017 0.0059
Plasmodium vivax SET domain protein, putative 0.0091 0.0903 0.3951
Loa Loa (eye worm) hypothetical protein 0.0073 0.0626 0.0716
Echinococcus granulosus expressed conserved protein 0.0091 0.0891 0.1285
Mycobacterium tuberculosis Conserved hypothetical protein 0.0155 0.1834 0.2372
Toxoplasma gondii deoxyuridine 5'-triphosphate nucleotidohydrolase, putative 0.017 0.2058 1
Mycobacterium ulcerans lipase LipD 0.0073 0.0626 0.1441
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.0903 0.3951
Trypanosoma brucei DNA polymerase kappa, putative 0.0066 0.0527 0.1019
Loa Loa (eye worm) dUTP diphosphatase 0.017 0.2058 0.2356
Echinococcus granulosus muscleblind protein 0.0152 0.1785 0.2574
Trypanosoma brucei DNA polymerase kappa, putative 0.0066 0.0527 0.1019
Echinococcus multilocularis dUTP pyrophosphatase 0.017 0.2058 0.2967
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0302 0.0414
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0626 0.8736 1
Schistosoma mansoni hypothetical protein 0.0503 0.6936 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.3761 0.3653
Entamoeba histolytica hypothetical protein 0.017 0.2058 0.4889

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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