Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.003 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.003 | 0.0083 |
Mycobacterium tuberculosis | Probable reductase | 0.0589 | 0.704 | 0.8958 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0589 | 0.704 | 0.8958 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0655 | 0.7857 | 1 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0589 | 0.704 | 0.8958 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0258 | 0.2923 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0064 | 0.0508 | 0.172 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0062 | 0.0479 | 0.1623 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0033 | 0.0122 | 0.0399 |
Loa Loa (eye worm) | intermediate filament protein | 0.0062 | 0.0479 | 0.1623 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.003 | 0.0083 |
Schistosoma mansoni | bromodomain containing protein | 0.0075 | 0.0647 | 0.0647 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0089 | 0.0824 | 0.2803 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0064 | 0.0508 | 0.172 |
Echinococcus granulosus | pyridine nucleotide disulfide oxidoreductase | 0.0024 | 0.0006 | 0.002 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0589 | 0.704 | 0.8958 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0039 | 0.0193 | 0.064 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0082 | 0.0259 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0089 | 0.0824 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0064 | 0.0508 | 0.0508 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0089 | 0.0824 | 0.2803 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0089 | 0.0824 | 0.2803 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0143 | 0.2728 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0089 | 0.0824 | 0.2777 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.0153 | 0.0505 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0089 | 0.0824 | 0.2803 |
Loa Loa (eye worm) | glutathione reductase | 0.0258 | 0.2923 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0141 | 0.147 | 1 |
Echinococcus multilocularis | musashi | 0.0062 | 0.0479 | 0.1616 |
Onchocerca volvulus | 0.0062 | 0.0479 | 0.3234 | |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0016 | 0.0016 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.0153 | 0.0505 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0416 | 0.1405 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0064 | 0.0508 | 0.172 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0089 | 0.0824 | 0.2803 |
Plasmodium falciparum | glutathione reductase | 0.0258 | 0.2923 | 1 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0064 | 0.0508 | 0.1711 |
Echinococcus granulosus | NADPH:adrenodoxin oxidoreductase | 0.0024 | 0.0006 | 0.002 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.0153 | 0.0517 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0067 | 0.0211 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0089 | 0.0824 | 0.2803 |
Echinococcus multilocularis | sulfide:quinone oxidoreductase | 0.0024 | 0.0006 | 0.002 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.016 | 0.1706 | 0.5828 |
Echinococcus granulosus | sulfide:quinone oxidoreductase | 0.0024 | 0.0006 | 0.002 |
Schistosoma mansoni | glutamate synthase | 0.0024 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0465 | 0.1575 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0153 | 0.1801 |
Trypanosoma brucei | trypanothione reductase | 0.0258 | 0.2923 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0153 | 0.1801 |
Echinococcus multilocularis | glutamate synthase | 0.0024 | 0.0006 | 0.002 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0025 | 0.0016 | 0.0033 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0089 | 0.0824 | 0.2803 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0089 | 0.0824 | 0.2803 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0153 | 0.1801 |
Brugia malayi | hypothetical protein | 0.0141 | 0.147 | 0.5018 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0089 | 0.0824 | 0.2777 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0089 | 0.0824 | 1 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0064 | 0.0508 | 0.172 |
Schistosoma mansoni | alpha-glucosidase | 0.0138 | 0.1428 | 0.1428 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0589 | 0.704 | 0.8958 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0089 | 0.0824 | 0.2803 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0089 | 0.0824 | 0.1042 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.016 | 0.1706 | 0.5752 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0589 | 0.704 | 0.8958 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0248 | 0.2801 | 0.9581 |
Plasmodium falciparum | glutathione reductase | 0.0089 | 0.0824 | 0.2803 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0655 | 0.7857 | 1 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.0153 | 0.0153 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0262 | 0.2966 | 1 |
Echinococcus multilocularis | lamin | 0.0062 | 0.0479 | 0.1616 |
Schistosoma mansoni | ap endonuclease | 0.0064 | 0.0508 | 0.0508 |
Brugia malayi | Thioredoxin reductase | 0.0258 | 0.2923 | 1 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0089 | 0.0824 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0062 | 0.0479 | 0.1616 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0193 | 0.0193 |
Leishmania major | trypanothione reductase | 0.0258 | 0.2923 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.0138 | 0.1428 | 0.1428 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0248 | 0.2801 | 0.9581 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.0153 | 0.0505 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0089 | 0.0824 | 0.2803 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.003 | 0.0083 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0143 | 0.2728 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.01 | 0.0955 | 0.3218 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0089 | 0.0824 | 0.2803 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0089 | 0.0824 | 0.2803 |
Brugia malayi | Bromodomain containing protein | 0.0089 | 0.082 | 0.279 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0033 | 0.0122 | 0.0399 |
Brugia malayi | MH2 domain containing protein | 0.0248 | 0.2801 | 0.9581 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0089 | 0.0824 | 0.0824 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0064 | 0.0508 | 0.172 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0143 | 0.0143 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0258 | 0.2923 | 0.3716 |
Treponema pallidum | NADH oxidase | 0.0089 | 0.0824 | 1 |
Schistosoma mansoni | glutamate synthase | 0.0024 | 0.0006 | 0.0006 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.0153 | 0.1801 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0027 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.01 | 0.0955 | 0.3252 |
Echinococcus multilocularis | NADPH:adrenodoxin oxidoreductase | 0.0024 | 0.0006 | 0.002 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0153 | 0.2936 |
Schistosoma mansoni | glutamate synthase | 0.0024 | 0.0006 | 0.0006 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0262 | 0.2966 | 1 |
Schistosoma mansoni | lamin | 0.0062 | 0.0479 | 0.0479 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0089 | 0.0824 | 0.2803 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0089 | 0.0824 | 0.2803 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.0153 | 0.1801 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0153 | 0.0505 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.01 | 0.0955 | 0.3218 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0193 | 0.064 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0153 | 0.1801 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0089 | 0.0824 | 1 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0064 | 0.0508 | 0.0639 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0153 | 0.2936 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0589 | 0.704 | 0.8958 |
Echinococcus granulosus | lamin dm0 | 0.0062 | 0.0479 | 0.1616 |
Echinococcus multilocularis | apoptosis inducing factor 1 mitochondrial | 0.0024 | 0.0006 | 0.002 |
Schistosoma mansoni | sulfide quinone reductase | 0.0024 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.147 | 0.5018 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0067 | 0.0211 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0153 | 0.0505 |
Brugia malayi | hypothetical protein | 0.0026 | 0.003 | 0.0083 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0143 | 0.2728 |
Schistosoma mansoni | disulfide oxidoreductase | 0.0024 | 0.0006 | 0.0006 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0027 | 0.0044 | 0.0148 |
Echinococcus granulosus | apoptosis inducing factor 1 mitochondrial | 0.0024 | 0.0006 | 0.002 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.01 | 0.0955 | 0.3218 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0313 | 0.1053 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0089 | 0.0824 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.003 | 0.0083 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0066 | 0.0528 | 0.179 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0089 | 0.0824 | 0.2803 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0024 | 0.0006 | 0.002 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0064 | 0.0508 | 0.172 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0153 | 0.1801 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0057 | 0.0416 | 0.1405 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0089 | 0.0824 | 0.2803 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0064 | 0.0508 | 0.6135 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0057 | 0.0416 | 0.1405 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.016 | 0.1706 | 0.5752 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.01 | 0.0955 | 0.3252 |
Schistosoma mansoni | lamin | 0.0062 | 0.0479 | 0.0479 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0043 | 0.0242 | 0.0816 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.147 | 0.5018 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0062 | 0.0479 | 0.1623 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0027 | 0.0044 | 0.0148 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0089 | 0.0824 | 0.2803 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0089 | 0.0824 | 0.2803 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0655 | 0.7857 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0089 | 0.0824 | 0.2803 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0153 | 0.1801 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0143 | 0.0482 |
Toxoplasma gondii | thioredoxin reductase | 0.0258 | 0.2923 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0089 | 0.0824 | 0.2803 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0258 | 0.2923 | 1 |
Toxoplasma gondii | exonuclease III APE | 0.0064 | 0.0508 | 0.172 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0024 | 0.0006 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0757 | 0.2573 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0089 | 0.0824 | 1 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0064 | 0.0508 | 0.6135 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0071 | 0.0594 | 0.2001 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0064 | 0.0508 | 0.6135 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0143 | 0.0482 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0064 | 0.0508 | 0.6135 |
Schistosoma mansoni | sulfide quinone reductase | 0.0024 | 0.0006 | 0.0006 |
Brugia malayi | Bromodomain containing protein | 0.0046 | 0.0277 | 0.0929 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0153 | 0.0505 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0064 | 0.0508 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0655 | 0.7857 | 1 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.003 | 0.0082 | 0.0275 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0066 | 0.0528 | 0.179 |
Echinococcus granulosus | intermediate filament protein | 0.0062 | 0.0479 | 0.1616 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0064 | 0.0508 | 0.6135 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0024 | 0.0006 | 0.002 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.01 | 0.0955 | 0.0955 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0089 | 0.0824 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0143 | 0.2728 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.003 | 0.0082 | 0.0275 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0143 | 0.0143 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0064 | 0.0508 | 0.172 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0024 | 0.0006 | 0.002 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.0079 | 0.025 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0089 | 0.0824 | 0.2803 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0089 | 0.0824 | 0.2803 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.01 | 0.0955 | 0.0955 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.01 | 0.0955 | 0.3218 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0064 | 0.0508 | 0.6135 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0064 | 0.0508 | 0.1711 |
Echinococcus granulosus | lamin | 0.0062 | 0.0479 | 0.1616 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0089 | 0.0824 | 0.2803 |
Plasmodium vivax | glutathione reductase, putative | 0.0258 | 0.2923 | 1 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0143 | 0.0469 |
Echinococcus multilocularis | pyridine nucleotide disulfide oxidoreductase | 0.0024 | 0.0006 | 0.002 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0089 | 0.0824 | 0.2803 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0089 | 0.0824 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.003 | 0.0083 |
Brugia malayi | intermediate filament protein | 0.0062 | 0.0479 | 0.1623 |
Schistosoma mansoni | intermediate filament proteins | 0.0062 | 0.0479 | 0.0479 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.0153 | 0.0505 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0064 | 0.0508 | 0.172 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0089 | 0.0824 | 0.2803 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0057 | 0.0416 | 0.1405 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0258 | 0.2923 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.003 | 0.0083 |
Echinococcus granulosus | glutamate synthase | 0.0024 | 0.0006 | 0.002 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.003 | 0.0083 |
Brugia malayi | glutathione reductase | 0.0258 | 0.2923 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0071 | 0.0594 | 0.2001 |
Onchocerca volvulus | 0.0062 | 0.0479 | 0.3234 | |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0089 | 0.0824 | 1 |
Onchocerca volvulus | 0.0093 | 0.0865 | 0.5866 | |
Onchocerca volvulus | Huntingtin homolog | 0.0141 | 0.147 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0043 | 0.0242 | 0.0816 |
Plasmodium falciparum | thioredoxin reductase | 0.0258 | 0.2923 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0479 | 0.1623 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0006 | 0.0006 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.0153 | 0.0517 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.016 | 0.1706 | 0.5752 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0341 | 0.115 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0278 | 0.0933 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.003 | 0.0083 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.016 | 0.1706 | 0.5828 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0153 | 0.1801 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.01 | 0.0955 | 0.0955 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 31.6228 uM | PubChem BioAssay. qHTS Assay for Inhibitors of the HIV-1 protein Vpr. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 32.6427 uM | PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.