Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.2369 | 0.2369 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.6893 | 0.6897 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.6468 | 0.6468 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.6893 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2369 | 0.237 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.6893 | 0.6897 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.2369 | 0.237 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.6893 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.9994 | 0.9994 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.6893 | 0.6897 |
Onchocerca volvulus | 0.0005 | 0 | 0.5 | |
Onchocerca volvulus | Basement membrane proteoglycan homolog | 0.0005 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2369 | 0.237 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.2369 | 0.237 |
Onchocerca volvulus | Arrow homolog | 0.0005 | 0 | 0.5 |
Onchocerca volvulus | 0.0005 | 0 | 0.5 | |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.2369 | 0.2369 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.2369 | 0.237 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2369 | 0.237 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.6468 | 0.6472 |
Brugia malayi | hypothetical protein | 0.0035 | 0.6893 | 0.6893 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.6468 | 0.6468 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.9994 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.2369 | 0.237 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.6893 | 0.6897 |
Onchocerca volvulus | 0.0005 | 0 | 0.5 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.9994 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.2369 | 0.237 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.9994 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.9994 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.9994 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 1 | 1 |
Onchocerca volvulus | 0.0005 | 0 | 0.5 | |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.6893 | 0.5 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.2369 | 0.2369 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.6893 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.2369 | 0.2369 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.9994 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.9994 | 0.9994 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.2369 | 0.237 |
Onchocerca volvulus | 0.0005 | 0 | 0.5 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.9994 | 1 |
Onchocerca volvulus | Terribly reduced optic lobes homolog | 0.0005 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2369 | 0.237 |
Onchocerca volvulus | 0.0005 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.