Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.042 | 0.084 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0002 | 0.0004 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.0701 | 0.0701 |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.032 | 0.3832 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0134 | 0.0645 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0039 | 0.0039 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0043 | 0.0439 | 0.0878 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.0671 | 0.1342 |
Trypanosoma cruzi | dihydroorotate dehydrogenase (fumarate), putative | 0.032 | 0.3832 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0024 | 0.0048 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.032 | 0.3832 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0039 | 0.0039 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0039 | 0.0078 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0701 | 0.1402 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0039 | 0.0102 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0361 | 0.0722 |
Schistosoma mansoni | dihydroorotate dehydrogenase | 0.032 | 0.3832 | 0.7662 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0039 | 0.0102 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0208 | 0.0544 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0039 | 0.0078 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.059 | 0.154 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0002 | 0.0002 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0361 | 0.1739 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0134 | 0.0645 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0039 | 0.0102 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.0701 | 0.338 |
Leishmania major | macrophage migration inhibitory factor-like protein | 0.0177 | 0.2075 | 0.5415 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0177 | 0.2075 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0122 | 0.0318 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0208 | 0.0544 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0189 |
Schistosoma mansoni | hypothetical protein | 0.0203 | 0.2398 | 0.4794 |
Onchocerca volvulus | Serine\/threonine protein kinase homolog | 0.0156 | 0.1826 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0039 | 0.0102 |
Wolbachia endosymbiont of Brugia malayi | dihydroorotate dehydrogenase 2 | 0.032 | 0.3832 | 0.5 |
Giardia lamblia | Macrophage migration inhibitory factor | 0.0177 | 0.2075 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0533 | 0.1392 |
Echinococcus granulosus | dnaJ subfamily B | 0.0416 | 0.5001 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0189 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0533 | 0.2571 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.0701 | 0.338 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0208 | 0.1004 |
Mycobacterium tuberculosis | Probable dihydroorotate dehydrogenase PyrD | 0.032 | 0.3832 | 1 |
Toxoplasma gondii | dihydroorotate dehydrogenase reveal, putative | 0.032 | 0.3832 | 1 |
Mycobacterium ulcerans | dihydroorotate dehydrogenase 2 | 0.032 | 0.3832 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0039 | 0.0189 |
Echinococcus multilocularis | tumor protein p63 | 0.0343 | 0.4116 | 0.4116 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0125 | 0.1444 | 0.2886 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0291 | 0.0582 |
Echinococcus multilocularis | proto oncogene serine:threonine protein kinase | 0.0156 | 0.1826 | 0.1826 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0039 | 0.0078 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0701 | 0.1402 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.011 | 0.0219 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0143 | 0.1664 | 0.1664 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.0134 | 0.0349 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0039 | 0.0078 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0039 | 0.0078 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0189 |
Plasmodium falciparum | dihydroorotate dehydrogenase | 0.032 | 0.3832 | 1 |
Echinococcus granulosus | expressed conserved protein | 0.0094 | 0.1064 | 0.2127 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0039 | 0.0078 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0189 |
Loa Loa (eye worm) | CAMK/PIM protein kinase | 0.0156 | 0.1826 | 0.8799 |
Leishmania major | macrophage migration inhibitory factor-like protein | 0.0177 | 0.2075 | 0.5415 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0337 | 0.0674 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0039 | 0.0102 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0125 | 0.1444 | 0.6956 |
Brugia malayi | RNA binding protein | 0.0064 | 0.0701 | 0.183 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0533 | 0.2571 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.005 | 0.0529 | 0.1057 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0039 | 0.0102 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.0125 | 0.1444 | 0.6956 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0208 | 0.1004 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0039 | 0.0102 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.011 | 0.0219 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0361 | 0.1739 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.0208 | 0.0544 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.0208 | 0.0544 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0039 | 0.0102 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.032 | 0.3832 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0208 | 0.1004 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.011 | 0.0528 |
Brugia malayi | Zinc finger, C2H2 type family protein | 0.0125 | 0.1444 | 0.3767 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0039 | 0.0078 |
Loa Loa (eye worm) | CAMK/PIM protein kinase | 0.0156 | 0.1826 | 0.8799 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0189 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0134 | 0.0645 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0439 | 0.2115 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.042 | 0.084 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0529 | 0.2547 |
Echinococcus multilocularis | protein patched | 0.0043 | 0.0439 | 0.0439 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0361 | 0.0942 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0134 | 0.0349 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0557 | 0.2685 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0024 | 0.0115 |
Plasmodium vivax | dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.032 | 0.3832 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.011 | 0.0219 |
Trypanosoma brucei | dihydroorotate dehydrogenase (fumarate) | 0.032 | 0.3832 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.042 | 0.084 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0143 | 0.1664 | 0.3326 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.011 | 0.0219 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0701 | 0.1402 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.0701 | 0.183 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.011 | 0.011 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0039 | 0.0102 |
Schistosoma mansoni | hypothetical protein | 0.0416 | 0.5001 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0039 | 0.0039 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.0208 | 0.0544 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0039 | 0.0078 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0125 | 0.1444 | 0.6956 |
Loa Loa (eye worm) | macrophage migration inhibitory factor 2 | 0.0075 | 0.0836 | 0.4027 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0533 | 0.1392 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0361 | 0.0361 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0208 | 0.0544 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0122 | 0.0318 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0208 | 0.1004 |
Plasmodium falciparum | macrophage migration inhibitory factor | 0.0177 | 0.2075 | 0.5415 |
Onchocerca volvulus | 0.001 | 0.0039 | 0.0214 | |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0002 | 0.0004 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.0134 | 0.0349 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0208 | 0.0544 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0156 | 0.1826 | 0.3651 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0271 | 0.1304 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0189 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0701 | 0.1402 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0039 | 0.0078 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0023 | 0.0059 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.01 | 0.1138 | 0.1138 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.011 | 0.011 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0122 | 0.0318 |
Mycobacterium leprae | Probable dihydroorotate dehydrogenase PyrD | 0.032 | 0.3832 | 1 |
Echinococcus granulosus | tumor protein p63 | 0.0343 | 0.4116 | 0.8231 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0039 | 0.0189 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0043 | 0.0439 | 0.0878 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0361 | 0.0722 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0208 | 0.1004 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0039 | 0.0078 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0039 | 0.0039 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0039 | 0.0078 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.011 | 0.0219 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0039 | 0.0078 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0039 | 0.0078 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0039 | 0.0102 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0002 | 0.0004 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0271 | 0.0706 |
Onchocerca volvulus | 0.0029 | 0.0271 | 0.1482 | |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0039 | 0.0102 |
Trypanosoma brucei | RNA helicase, putative | 0.0203 | 0.2398 | 0.6257 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0134 | 0.0645 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.0208 | 0.0544 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0361 | 0.1739 |
Echinococcus multilocularis | expressed conserved protein | 0.0094 | 0.1064 | 0.1064 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0134 | 0.5 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.01 | 0.1138 | 0.5484 |
Loa Loa (eye worm) | macrophage migration inhibitory factor | 0.0177 | 0.2075 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0039 | 0.0189 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0039 | 0.0102 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0208 | 0.0544 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0271 | 0.0541 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0291 | 0.0582 |
Echinococcus granulosus | proto oncogene serine:threonine protein kinase | 0.0156 | 0.1826 | 0.3651 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0125 | 0.1444 | 0.2886 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0122 | 0.0318 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0125 | 0.1444 | 0.1444 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0039 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.011 | 0.0528 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0039 | 0.0214 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0125 | 0.1444 | 0.6956 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0208 | 0.0544 |
Schistosoma mansoni | patched 1 | 0.0043 | 0.0439 | 0.0878 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0208 | 0.0544 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0134 | 0.0349 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0039 | 0.0189 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0134 | 0.0645 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0039 | 0.0102 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.011 | 0.0286 |
Entamoeba histolytica | macrophage migration inhibitory factor-like protein | 0.0177 | 0.2075 | 1 |
Leishmania major | dihydroorotate dehydrogenase | 0.032 | 0.3832 | 1 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0102 | 0.1157 | 0.2313 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.0701 | 0.183 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.0701 | 0.338 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0039 | 0.0039 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0024 | 0.0024 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0039 | 0.0078 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0043 | 0.0439 | 0.2115 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0125 | 0.1444 | 0.3767 |
Echinococcus multilocularis | protein dispatched 1 | 0.0049 | 0.0513 | 0.0513 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0337 | 0.088 |
Brugia malayi | Bm-MIF-1, identical | 0.0177 | 0.2075 | 0.5415 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0039 | 0.0078 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0291 | 0.0582 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.011 | 0.011 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0039 | 0.0078 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0039 | 0.0102 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0039 | 0.0102 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0039 | 0.0214 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.011 | 0.0219 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.011 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0337 | 0.1625 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0039 | 0.0189 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0039 | 0.0078 |
Brugia malayi | CHE-14 protein | 0.0043 | 0.0439 | 0.1145 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0039 | 0.0078 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.0208 | 0.0544 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0361 | 0.1739 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0208 | 0.0544 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0039 | 0.0039 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.0701 | 0.1402 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0416 | 0.5001 | 0.5001 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0039 | 0.0102 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0125 | 0.1444 | 0.6956 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0024 | 0.0208 | 0.1004 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0208 | 0.0544 |
Brugia malayi | Serine/threonine-protein kinase Pim-3 | 0.0156 | 0.1826 | 0.4765 |
Loa Loa (eye worm) | macrophage migration inhibitory factor 2 | 0.0075 | 0.0836 | 0.4027 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0701 | 0.1402 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0039 | 0.0189 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0125 | 0.1444 | 0.6956 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.042 | 0.084 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0039 | 0.0078 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0208 | 0.0544 |
Trichomonas vaginalis | macrophage migration inhibitory factor, mif, putative | 0.0177 | 0.2075 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0039 | 0.0189 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0043 | 0.0439 | 0.0439 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0361 | 0.0722 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1138 | 0.5484 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0189 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0039 | 0.0078 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0039 | 0.0078 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.0208 | 0.0544 |
Plasmodium vivax | macrophage migration inhibitory factor, putative | 0.0177 | 0.2075 | 0.5415 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.011 | 0.0286 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0002 | 0.0002 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0125 | 0.1444 | 0.1444 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0039 | 0.0102 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0039 | 0.0102 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0208 | 0.0544 |
Brugia malayi | Protein kinase domain containing protein | 0.0156 | 0.1826 | 0.4765 |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.032 | 0.3832 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0039 | 0.0214 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0039 | 0.0102 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0039 | 0.0189 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0039 | 0.0039 |
Onchocerca volvulus | 0.005 | 0.0529 | 0.2895 | |
Onchocerca volvulus | 0.0024 | 0.0208 | 0.1141 | |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0208 | 0.0544 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0291 | 0.0291 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.01 | 0.1138 | 0.297 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.01 | 0.1138 | 0.2276 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0125 | 0.1444 | 0.6956 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0189 |
Toxoplasma gondii | macrophage migration inhibitory factor, putative | 0.0177 | 0.2075 | 0.5415 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0039 | 0.0078 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0439 | 0.2115 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.