Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.6421 | 0.6421 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.7367 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.7367 | 0.7367 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 1 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.7367 | 0.7367 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Onchocerca volvulus | 0.0024 | 1 | 1 | |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.7367 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.6421 | 0.6421 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.7367 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.7367 | 0.7367 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.6421 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.7367 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.6421 | 0.6421 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.379 | 0.5145 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 1 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.7367 | 1 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0007 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.7367 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.5844 | 0.5844 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 1 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.6421 | 0.6421 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.7367 | 0.7367 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 1 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.379 | 0.5145 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.7367 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.379 | 0.5145 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.7367 | 0.7367 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.7367 | 0.7367 |
Trypanosoma brucei | unspecified product | 0.0013 | 0.379 | 0.5145 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 1 | 1 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.7367 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.7367 | 1 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.7367 | 1 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.7367 | 0.7367 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.7367 | 0.7367 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.7367 | 0.7367 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.7367 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 1 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.5844 | 0.5844 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0007 | 0 | 0.5 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.7367 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 1 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.6421 | 0.6421 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 1 | 1 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.7367 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.6421 | 0.6421 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.5844 | 0.5844 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 1 | 1 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0024 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.7367 | 1 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.7367 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.7367 | 0.7367 |
Toxoplasma gondii | propionate-CoA ligase | 0.0007 | 0 | 0.5 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.7367 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.5844 | 0.5844 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.6421 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.6421 | 0.5 |
Trypanosoma brucei | unspecified product | 0.0013 | 0.379 | 0.5145 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 1 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.7367 | 0.7367 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.7367 | 0.7367 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.6421 | 0.6421 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 1 | 1 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.7367 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 1 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 1 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.7367 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.