Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0582 | 0.9856 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0582 | 0.9856 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0582 | 0.9856 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0582 | 0.9856 | 1 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.0169 | 0.2317 | 0.2351 |
Echinococcus granulosus | aldehyde reductase | 0.0413 | 0.6782 | 0.6881 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.059 | 1 | 1 |
Onchocerca volvulus | 0.0582 | 0.9856 | 1 | |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0169 | 0.2317 | 0.2351 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0582 | 0.9856 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0582 | 0.9856 | 0.9856 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0169 | 0.2317 | 0.2351 |
Echinococcus multilocularis | aldo keto reductase | 0.0582 | 0.9856 | 1 |
Echinococcus multilocularis | aldehyde reductase | 0.0413 | 0.6782 | 0.6881 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0582 | 0.9856 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0582 | 0.9856 | 1 |
Mycobacterium leprae | Possible oxidoreductase | 0.0169 | 0.2317 | 0.2351 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0582 | 0.9856 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0582 | 0.9856 | 1 |
Brugia malayi | NADH-dependent xylose reductase | 0.0169 | 0.2317 | 0.2351 |
Loa Loa (eye worm) | oxidoreductase | 0.0582 | 0.9856 | 1 |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0042 | 0 | 0.5 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0582 | 0.9856 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0582 | 0.9856 | 1 |
Leishmania major | prostaglandin f synthase, putative | 0.0582 | 0.9856 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0582 | 0.9856 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0582 | 0.9856 | 1 |
Toxoplasma gondii | oxidoreductase, aldo/keto reductase family protein | 0.0169 | 0.2317 | 0.2351 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0582 | 0.9856 | 1 |
Onchocerca volvulus | 0.0582 | 0.9856 | 1 | |
Plasmodium falciparum | aldo-keto reductase, putative | 0.0169 | 0.2317 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0582 | 0.9856 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0582 | 0.9856 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0582 | 0.9856 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0582 | 0.9856 | 1 |
Leishmania major | aldo-keto reductase-like protein | 0.0582 | 0.9856 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0582 | 0.9856 | 1 |
Schistosoma mansoni | potassium channel beta | 0.0169 | 0.2317 | 0.2351 |
Toxoplasma gondii | aldo/keto reductase family oxidoreductase | 0.0169 | 0.2317 | 0.2351 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0582 | 0.9856 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0582 | 0.9856 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0582 | 0.9856 | 1 |
Onchocerca volvulus | 0.0169 | 0.2317 | 0.2351 | |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.0169 | 0.2317 | 1 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0548 | 0.9242 | 0.9378 |
Echinococcus granulosus | aldo keto reductase | 0.0582 | 0.9856 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0582 | 0.9856 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0582 | 0.9856 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0582 | 0.9856 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0582 | 0.9856 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0582 | 0.9856 | 1 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.0169 | 0.2317 | 0.2351 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.0169 | 0.2317 | 0.2351 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0582 | 0.9856 | 1 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0582 | 0.9856 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0582 | 0.9856 | 1 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0582 | 0.9856 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0582 | 0.9856 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0582 | 0.9856 | 1 |
Onchocerca volvulus | 0.0582 | 0.9856 | 1 | |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0169 | 0.2317 | 0.2351 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0582 | 0.9856 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0582 | 0.9856 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0582 | 0.9856 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0582 | 0.9856 | 1 |
Trypanosoma cruzi | aldo-keto reductase | 0.0582 | 0.9856 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0582 | 0.9856 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0582 | 0.9856 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0582 | 0.9856 | 1 |
Schistosoma mansoni | pol-related | 0.0582 | 0.9856 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0582 | 0.9856 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0582 | 0.9856 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0582 | 0.9856 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0582 | 0.9856 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0582 | 0.9856 | 1 |
Onchocerca volvulus | 0.0582 | 0.9856 | 1 | |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0582 | 0.9856 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0582 | 0.9856 | 1 |
Onchocerca volvulus | 0.0582 | 0.9856 | 1 | |
Entamoeba histolytica | aldose reductase, putative | 0.0582 | 0.9856 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0582 | 0.9856 | 1 |
Leishmania major | aldo/keto reductase, putative,aldo/keto reductase family-like protein | 0.0169 | 0.2317 | 0.2351 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0582 | 0.9856 | 1 |
Giardia lamblia | Aldose reductase | 0.0582 | 0.9856 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0169 | 0.2317 | 0.2317 |
Plasmodium vivax | aldehyde reductase, putative | 0.0169 | 0.2317 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0582 | 0.9856 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0169 | 0.2317 | 0.2351 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0582 | 0.9856 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0582 | 0.9856 | 1 |
Toxoplasma gondii | aldose reductase, putative | 0.0582 | 0.9856 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0413 | 0.6782 | 0.6881 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0582 | 0.9856 | 1 |
Plasmodium falciparum | aldehyde reductase, putative | 0.0169 | 0.2317 | 1 |
Onchocerca volvulus | 0.0582 | 0.9856 | 1 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0582 | 0.9856 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0582 | 0.9856 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0582 | 0.9856 | 1 |
Giardia lamblia | Aldose reductase | 0.0582 | 0.9856 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0582 | 0.9856 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0582 | 0.9856 | 1 |
Toxoplasma gondii | aldo-keto reductase | 0.0169 | 0.2317 | 0.2351 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0582 | 0.9856 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0582 | 0.9856 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0582 | 0.9856 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0582 | 0.9856 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0582 | 0.9856 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0582 | 0.9856 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.