Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0042 | 0.0669 | 0.0669 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0073 | 0.2758 | 0.5223 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0251 | 0.0251 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0103 | 0.4728 | 0.4728 |
Loa Loa (eye worm) | hypothetical protein | 0.0111 | 0.5281 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0111 | 0.5281 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0111 | 0.5281 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0103 | 0.4728 | 0.4728 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0669 | 0.5 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0 | 0.5 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0035 | 0.0251 | 0.0474 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0251 | 0.0474 |
Schistosoma mansoni | jumonji domain containing protein | 0.0082 | 0.3329 | 0.3329 |
Plasmodium vivax | hypothetical protein, conserved | 0.0031 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.2758 | 0.2758 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.2758 | 0.2758 |
Loa Loa (eye worm) | TAR-binding protein | 0.0073 | 0.2758 | 0.5223 |
Giardia lamblia | PHD finger protein 15 | 0.0031 | 0 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0042 | 0.0669 | 0.0669 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.2758 | 0.2758 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0038 | 0.0437 | 0.0437 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0669 | 0.0669 |
Echinococcus multilocularis | geminin | 0.0183 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0073 | 0.2758 | 0.2758 |
Echinococcus granulosus | jumonji domain containing protein | 0.0044 | 0.0814 | 0.0814 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0038 | 0.0437 | 0.0437 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0251 | 0.0251 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0111 | 0.5281 | 1 |
Onchocerca volvulus | Alhambra homolog | 0.0031 | 0 | 0.5 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0038 | 0.0437 | 0.0437 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0 | 0.5 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0035 | 0.0251 | 0.0474 |
Schistosoma mansoni | hypothetical protein | 0.0183 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0251 | 0.0251 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0669 | 0.1266 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0076 | 0.2953 | 0.5591 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0073 | 0.2758 | 0.5223 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.2953 | 0.5591 |
Loa Loa (eye worm) | RNA binding protein | 0.0073 | 0.2758 | 0.5223 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0669 | 0.5 |
Echinococcus granulosus | GPCR family 2 | 0.0035 | 0.0251 | 0.0251 |
Brugia malayi | jmjC domain containing protein | 0.0038 | 0.0437 | 0.0828 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0038 | 0.0437 | 0.0437 |
Schistosoma mansoni | hypothetical protein | 0.0183 | 1 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0065 | 0.2213 | 0.419 |
Brugia malayi | jmjC domain containing protein | 0.0103 | 0.4728 | 0.8952 |
Brugia malayi | TAR-binding protein | 0.0073 | 0.2758 | 0.5223 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0035 | 0.0251 | 0.0251 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0035 | 0.0251 | 0.0474 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.2758 | 0.2758 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0251 | 0.0251 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0669 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1485 | 0.2811 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0035 | 0.0251 | 0.0251 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.2758 | 0.2758 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0669 | 0.5 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0035 | 0.0251 | 0.0251 |
Plasmodium falciparum | phd finger protein, putative | 0.0031 | 0 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0073 | 0.2758 | 0.2758 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0042 | 0.0669 | 0.0669 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.2953 | 0.2953 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0044 | 0.0814 | 0.0814 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0038 | 0.0437 | 0.0828 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0035 | 0.0251 | 0.0251 |
Brugia malayi | RNA binding protein | 0.0073 | 0.2758 | 0.5223 |
Echinococcus multilocularis | GPCR, family 2 | 0.0035 | 0.0251 | 0.0251 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.