Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0041 | 0.0548 | 0.5 | |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0548 | 0.1008 |
Schistosoma mansoni | choline o-acyltransferase | 0.0041 | 0.0548 | 1 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0 | 0.5 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.002 | 0 | 0.5 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0041 | 0.0548 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.016 | 0.0294 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0041 | 0.0548 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.016 | 0.2914 |
Trypanosoma cruzi | carnitine O-acetyltransferase, putative | 0.0041 | 0.0548 | 0.1008 |
Loa Loa (eye worm) | choline O-acetyltransferase | 0.0041 | 0.0548 | 0.0548 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0548 | 0.0548 |
Onchocerca volvulus | 0.0041 | 0.0548 | 0.5 | |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0 | 0.5 |
Brugia malayi | Choline O-acetyltransferase | 0.0041 | 0.0548 | 0.0548 |
Trypanosoma cruzi | carnitine/choline acetyltransferase, putative | 0.0041 | 0.0548 | 0.1008 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0041 | 0.0548 | 0.0548 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.016 | 0.016 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0548 | 0.1008 |
Echinococcus granulosus | carnitine O palmitoyltransferase 2 | 0.0041 | 0.0548 | 0.1008 |
Echinococcus granulosus | choline O acetyltransferase | 0.0041 | 0.0548 | 0.1008 |
Loa Loa (eye worm) | hypothetical protein | 0.0392 | 1 | 1 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 2 | 0.0041 | 0.0548 | 0.1008 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0548 | 0.1008 |
Leishmania major | carnitine/choline acetyltransferase, putative | 0.0041 | 0.0548 | 0.1008 |
Trypanosoma cruzi | carnitine O-palmitoyltransferase II, putative | 0.0041 | 0.0548 | 0.1008 |
Trypanosoma brucei | carnitine O-acetyltransferase, putative | 0.0041 | 0.0548 | 1 |
Brugia malayi | Choline O-acetyltransferase | 0.0041 | 0.0548 | 0.0548 |
Schistosoma mansoni | choline o-acyltransferase | 0.0041 | 0.0548 | 1 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0041 | 0.0548 | 0.1008 |
Echinococcus granulosus | carnitine O palmitoyltransferase 1 liver | 0.0222 | 0.5441 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0548 | 0.1008 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0548 | 0.1008 |
Leishmania major | choline/Carnitine o-acyltransferase-like protein | 0.0222 | 0.5441 | 1 |
Leishmania major | carnitine palmitoyltransferase-like protein | 0.0041 | 0.0548 | 0.1008 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0 | 0.5 |
Onchocerca volvulus | 0.0041 | 0.0548 | 0.5 | |
Trypanosoma brucei | carnitine O-palmitoyltransferase, putative | 0.0041 | 0.0548 | 1 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0222 | 0.5441 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.016 | 1 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0041 | 0.0548 | 1 |
Loa Loa (eye worm) | carnitine O-palmitoyltransferase I isoform | 0.0041 | 0.0548 | 0.0548 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.016 | 1 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0041 | 0.0548 | 0.0548 |
Trypanosoma cruzi | choline/carnitine O-acetyltransferase, putative | 0.0041 | 0.0548 | 0.1008 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.002 | 0 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.016 | 0.0294 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.002 | 0 | 0.5 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.016 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.016 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.016 | 0.0294 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0222 | 0.5441 | 1 |
Echinococcus multilocularis | choline O acetyltransferase | 0.0041 | 0.0548 | 0.1008 |
Onchocerca volvulus | 0.0041 | 0.0548 | 0.5 | |
Loa Loa (eye worm) | choline/Carnitine O-acyltransferase | 0.0041 | 0.0548 | 0.0548 |
Trypanosoma cruzi | carnitine/choline acetyltransferase, putative | 0.0041 | 0.0548 | 0.1008 |
Brugia malayi | hypothetical protein | 0.0026 | 0.016 | 0.016 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 1, liver | 0.0222 | 0.5441 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.