Detailed information for compound 68115

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 516.381 | Formula: C25H26BrNO6--
  • H donors: 0 H acceptors: 5 LogP: 4.45 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(C(c1ccc(cc1)Br)C)OC1CC2CCC(C1)N2Cc1ccccc1.[O-]C(=O)C(=O)[O-]
  • InChi: 1S/C23H26BrNO2.C2H2O4/c1-16(18-7-9-19(24)10-8-18)23(26)27-22-13-20-11-12-21(14-22)25(20)15-17-5-3-2-4-6-17;3-1(4)2(5)6/h2-10,16,20-22H,11-15H2,1H3;(H,3,4)(H,5,6)/p-2
  • InChiKey: HLTFBPFCSHOPMV-UHFFFAOYSA-L  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi NADH dehydrogenase, putative 0.0053 0.0508 0.0965
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0047 0.0427 0.0502
Schistosoma mansoni lamin 0.0028 0.0211 0.0248
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0632 0.1812
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0011 0.0006 0.0001
Schistosoma mansoni voltage-gated potassium channel 0.0053 0.0508 0.0598
Brugia malayi hypothetical protein 0.0039 0.0339 0.064
Trichomonas vaginalis conserved hypothetical protein 0.0303 0.3466 0.8248
Trichomonas vaginalis Ferredoxin 1 0.0012 0.0013 0.0018
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0074 0.007
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0053 0.0508 0.1196
Brugia malayi GnHR receptor homolog 0.0039 0.0339 0.064
Brugia malayi RE15519p 0.0039 0.0339 0.064
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0303 0.3466 0.8248
Schistosoma mansoni adenoreceptor 0.0039 0.0339 0.0399
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0063 0.0626 0.119
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0095 0.0261
Loa Loa (eye worm) hypothetical protein 0.0026 0.0182 0.0331
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.3524 0.8385
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.031 0.3554 1
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0279 0.3182 0.6095
Plasmodium vivax glutathione reductase, putative 0.045 0.5217 1
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0047 0.0426 0.0502
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0062 0.0073
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0053 0.0508 0.0593
Echinococcus multilocularis neuropeptides capa receptor 0.0039 0.0339 0.0335
Loa Loa (eye worm) hypothetical protein 0.0016 0.007 0.0127
Mycobacterium ulcerans hypothetical protein 0.0021 0.0126 0.0349
Brugia malayi hypothetical protein 0.0039 0.0339 0.064
Leishmania major protein kinase, putative 0.0014 0.0037 0.0063
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0126 0.0349
Echinococcus granulosus phd:f box containing protein 0.0016 0.007 0.0077
Brugia malayi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0064 0.0638 0.1214
Trypanosoma brucei developmentally regulated phosphoprotein 0.0015 0.0056 0.0098
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0435 0.0826
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0303 0.3466 0.8248
Entamoeba histolytica P-glycoprotein-1 0.0011 0.0006 0.0016
Leishmania major Bem46-like serine peptidase,Serine peptidase, Clan SC, Family S09X 0.0026 0.0182 0.0341
Echinococcus granulosus neuropeptide s receptor 0.0523 0.6084 0.7163
Schistosoma mansoni hypothetical protein 0.0053 0.0508 0.0598
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0015 0.0056 0.0061
Leishmania major cytochrome p450-like protein 0.0024 0.016 0.0298
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0016 0.0066 0.0268
Loa Loa (eye worm) voltage-dependent calcium channel 0.0076 0.0772 0.1401
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0336 0.0635
Leishmania major heat shock protein 83-1 0.0015 0.0056 0.0098
Trypanosoma brucei monoglyceride lipase, putative 0.0303 0.3466 0.6641
Plasmodium vivax metacaspase 1, putative 0.0047 0.0426 0.0817
Brugia malayi Uncoordinated protein 44 0.0015 0.0053 0.0092
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0053 0.0508 0.1452
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0032 0.0052
Schistosoma mansoni family S9 unassigned peptidase (S09 family) 0.0026 0.0182 0.0215
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0176 0.0407
Brugia malayi Tachykinin-like peptides receptor 99D 0.0039 0.0339 0.064
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0053 0.0508 0.0504
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0015 0.0056 0.0069
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.007 0.07 0.2009
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Brugia malayi nuclear receptor RXR 0.0015 0.0052 0.009
Echinococcus multilocularis neuropeptide receptor A26 0.0523 0.6084 0.6082
Echinococcus granulosus neuropeptide Y receptor 0.0039 0.0339 0.0394
Brugia malayi jmjC domain containing protein 0.0016 0.007 0.0123
Schistosoma mansoni sulfide quinone reductase 0.0053 0.0508 0.0598
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.0026 0.0182 0.035
Brugia malayi G-protein coupled receptor 0.0039 0.0339 0.064
Mycobacterium leprae putative cytochrome p450 0.0015 0.0051 0.0054
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.051 0.1203
Trypanosoma brucei trypanothione reductase 0.045 0.5217 1
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0435 0.0512
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0201 0.2261 0.4329
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.3524 0.8385
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0014 0.0035 0.0037
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0053 0.0508 0.0593
Echinococcus multilocularis caspase 0.0123 0.1334 0.1331
Loa Loa (eye worm) hypothetical protein 0.0015 0.0052 0.0095
Loa Loa (eye worm) hypothetical protein 0.0128 0.1399 0.2539
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0336 0.0395
Onchocerca volvulus 0.0039 0.0339 0.1176
Loa Loa (eye worm) hypothetical protein 0.0045 0.0405 0.0735
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0071 0.0127
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0364 0.4201 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0126 0.0228
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0015 0.0051 0.0087
Trypanosoma brucei heat shock protein, putative 0.0015 0.0056 0.0098
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Trypanosoma brucei heat shock protein 90, putative 0.0015 0.0056 0.0098
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0053 0.0508 0.0965
Echinococcus granulosus muscleblind protein 0.0157 0.1739 0.2044
Echinococcus granulosus abhydrolase domain containing protein 13 0.0026 0.0182 0.021
Loa Loa (eye worm) hypothetical protein 0.0015 0.0052 0.0095
Brugia malayi glutathione reductase 0.045 0.5217 1
Loa Loa (eye worm) hypothetical protein 0.0157 0.1739 0.3157
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0053 0.0508 0.0973
Brugia malayi putative neuropeptide receptor NPR1 0.0039 0.0339 0.064
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0051 0.0088
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0252 0.0248
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.012 0.0137
Toxoplasma gondii ferodoxin FD 0.0012 0.0013 0.0025
Echinococcus granulosus caspase 2 0.009 0.0941 0.1104
Echinococcus granulosus neuropeptides capa receptor 0.0039 0.0339 0.0394
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0063 0.0626 0.12
Brugia malayi voltage-dependent calcium channel 0.0014 0.0035 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0032 0.0062
Brugia malayi Carboxylesterase family protein 0.0047 0.0427 0.0808
Trypanosoma cruzi DNA polymerase kappa, putative 0.0063 0.0628 0.1195
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0053 0.0508 0.0965
Loa Loa (eye worm) endoplasmin 0.0015 0.0056 0.0102
Echinococcus granulosus dna polymerase eta 0.0036 0.0296 0.0343
Mycobacterium tuberculosis Possible oxygenase 0.0012 0.0013 0.0014
Brugia malayi ImpB/MucB/SamB family protein 0.0036 0.0296 0.0557
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0095 0.0173
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0015 0.0056 0.0148
Echinococcus granulosus cytochrome P450 2K1 0.0015 0.0051 0.0055
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0032 0.0028
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0426 0.1003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0176 0.0407
Schistosoma mansoni rab6-interacting 0.0021 0.012 0.0141
Giardia lamblia [2Fe-2S] ferredoxin 0.0012 0.0013 0.0023
Schistosoma mansoni flap endonuclease-1 0.0025 0.0168 0.0198
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0252 0.0297
Mycobacterium ulcerans hypothetical protein 0.0026 0.0182 0.0513
Brugia malayi Inositol-1 0.0039 0.0335 0.0632
Mycobacterium tuberculosis Possible two component sensor kinase 0.0015 0.0056 0.0097
Leishmania major mitochondrial DNA polymerase beta 0.0318 0.3645 0.6985
Echinococcus granulosus BC026374 protein S09 family 0.0047 0.0427 0.0498
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0435 0.1024
Plasmodium vivax DNA repair protein REV1, putative 0.0011 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0475 0.5509 1
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0016 0.0066 0.0078
Echinococcus granulosus single minded 2 0.0041 0.0366 0.0426
Treponema pallidum fructose-bisphosphate aldolase 0.0307 0.3524 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.007 0.0125
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0071 0.0067
Brugia malayi CXXC zinc finger family protein 0.003 0.0232 0.0436
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0053 0.0508 0.0973
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.3524 0.8385
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0426 0.1003
Toxoplasma gondii hypothetical protein 0.0016 0.0066 0.0127
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0323 0.0381
Brugia malayi DNA topoisomerase III beta-1 0.0016 0.0063 0.0109
Echinococcus granulosus apoptotic protease activating factor 1 0.0043 0.0388 0.0453
Echinococcus multilocularis g protein coupled receptor 0.0039 0.0339 0.0335
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0015 0.0051 0.0087
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0064 0.0638 0.1216
Loa Loa (eye worm) hypothetical protein 0.0062 0.061 0.1108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0062 0.0135
Trypanosoma brucei metacaspase 5, putative 0.0047 0.0426 0.0809
Loa Loa (eye worm) hypothetical protein 0.0032 0.0252 0.0458
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0201 0.2261 0.4334
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0012 0.0013 0.0014
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0189 0.0353
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0053 0.0508 0.22
Chlamydia trachomatis ferredoxin 0.0012 0.0013 0.0033
Entamoeba histolytica 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0105 0.1121 0.3154
Plasmodium falciparum ferrodoxin reductase-like protein 0.0053 0.0508 0.0965
Schistosoma mansoni hypothetical protein 0.0021 0.012 0.0141
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0047 0.0427 0.0808
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0015 0.0013
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.0252 0.0297
Echinococcus granulosus tm gpcr rhodopsin 0.0039 0.0339 0.0394
Loa Loa (eye worm) hypothetical protein 0.0015 0.0052 0.0095
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0006 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0339 0.0335
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.017 0.0477
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0053 0.0508 0.1452
Schistosoma mansoni adrenodoxin 0.0012 0.0013 0.0015
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0052 0.009
Echinococcus multilocularis sodium and chloride dependent glycine 0.0016 0.0066 0.0062
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.0252 0.0297
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0011 0.0006 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0177 0.0408
Chlamydia trachomatis acyltransferase family protein 0.0026 0.0182 0.0784
Schistosoma mansoni coup transcription factor 0.0032 0.0252 0.0297
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0015 0.0051 0.0087
Trypanosoma cruzi heat shock protein 85, putative 0.0015 0.0056 0.0098
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0335 0.0785
Schistosoma mansoni cytochrome P450 0.0015 0.0051 0.006
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.007 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0291 0.0681
Treponema pallidum thioredoxin reductase (trxB) 0.0053 0.0508 0.144
Echinococcus granulosus tachykinin peptides receptor 99D 0.0039 0.0339 0.0394
Leishmania major developmentally regulated phosphoprotein-like protein 0.0015 0.0056 0.0098
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0016 0.0066 0.0078
Brugia malayi AMP-binding enzyme family protein 0.0025 0.017 0.0315
Schistosoma mansoni zinc finger protein 0.0015 0.0052 0.0062
Plasmodium vivax ferredoxin, putative 0.0012 0.0013 0.0025
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0039 0.0339 0.0399
Plasmodium falciparum alpha/beta hydrolase, putative 0.0026 0.0182 0.0341
Echinococcus multilocularis two pore calcium channel protein 1 0.0014 0.0035 0.0031
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.012
Plasmodium falciparum multidrug resistance protein 1 0.0011 0.0006 0.0001
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0015 0.0056 0.0148
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0632 0.1812
Trypanosoma cruzi DNA polymerase kappa, putative 0.0063 0.0628 0.1195
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0014 0.0035 0.0037
Onchocerca volvulus 0.0015 0.0057 0.0182
Leishmania major heat shock protein 83-1 0.0015 0.0056 0.0098
Echinococcus multilocularis somatostatin receptor 0.0039 0.0339 0.0335
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.0252 0.0474
Brugia malayi Cell death protein 3 precursor 0.009 0.0941 0.1794
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0019 0.0096 0.0109
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0404 0.0766
Brugia malayi follicle stimulating hormone receptor 0.0281 0.3211 0.6151
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0015 0.0056 0.0097
Schistosoma mansoni neuropeptide f receptor 76f 0.0039 0.0339 0.0399
Echinococcus granulosus 7TM GPCR rhodopsin 0.0039 0.0339 0.0394
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0063 0.0626 0.2726
Leishmania major cytochrome p450-like protein 0.0015 0.0051 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0435 0.1024
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0015 0.0056 0.0098
Entamoeba histolytica P-glycoprotein-2 0.0011 0.0006 0.0016
Plasmodium falciparum lysophospholipase, putative 0.0303 0.3466 0.6641
Brugia malayi nuclear receptor RXR 0.0017 0.0074 0.0131
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.007 0.07 0.1333
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0336 0.0633
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0039 0.0339 0.0399
Echinococcus granulosus G protein coupled receptor 139 0.0039 0.0339 0.0394
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.051 0.097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0062 0.0135
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0182 0.0422
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0053 0.0508 0.1196
Mycobacterium ulcerans monoxygenase 0.0053 0.0508 0.1452
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0107 0.0196
Echinococcus granulosus abhydrolase domain containing 3 0.0026 0.0182 0.021
Entamoeba histolytica deoxycytidyl transferase, putative 0.0036 0.0296 0.0832
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0015 0.0056 0.012
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.0252 0.0293
Echinococcus granulosus nuclear receptor nhr 48 0.0015 0.0052 0.0057
Brugia malayi intermediate filament protein 0.0028 0.0211 0.0394
Plasmodium falciparum prodrug activation and resistance esterase 0.0026 0.0182 0.0341
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.017 0.0392
Brugia malayi nuclear receptor NHR-67 0.0015 0.0052 0.009
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0026 0.0182 0.0422
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0162 0.18 0.3444
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0508 0.0965
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0014 0.0035 0.0031
Echinococcus multilocularis neuropeptide Y receptor 0.0039 0.0339 0.0335
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0064
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0096 0.0113
Echinococcus granulosus geminin 0.0178 0.199 0.234
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0015 0.0056 0.0097
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0016 0.0066 0.0073
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0339 0.0394
Brugia malayi Carboxylesterase family protein 0.0047 0.0427 0.0808
Loa Loa (eye worm) calcium channel 0.0128 0.1399 0.2539
Brugia malayi conserved hypotetical protein 0.0015 0.0052 0.009
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0015 0.0051 0.0133
Loa Loa (eye worm) hypothetical protein 0.0017 0.0074 0.0134
Brugia malayi polk-prov protein 0.0039 0.0337 0.0636
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0014 0.0035 0.0031
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0335 0.0785
Schistosoma mansoni acetylcholinesterase 0.0047 0.0427 0.0502
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0201 0.2261 0.4329
Onchocerca volvulus 0.0095 0.1006 0.3529
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0014 0.0035 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0209 0.0485
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0015 0.0051 0.0087
Echinococcus multilocularis sodium leak channel non selective protein 0.0014 0.0035 0.0031
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Schistosoma mansoni jumonji domain containing protein 0.0062 0.0608 0.0716
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0071 0.0067
Echinococcus granulosus multidrug resistance protein 1 0.0011 0.0006 0.0002
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0026 0.0182 0.0422
Loa Loa (eye worm) DR-78 0.0015 0.0052 0.0095
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0035 0.0031
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0638 0.0635
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0036 0.0032
Plasmodium falciparum glutathione reductase 0.0201 0.2261 0.4329
Chlamydia trachomatis hydrolase 0.0026 0.0182 0.0784
Schistosoma mansoni hypothetical protein 0.0178 0.199 0.2343
Onchocerca volvulus 0.0021 0.012 0.0404
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0339 0.0394
Schistosoma mansoni voltage-gated cation channel 0.0128 0.1399 0.1647
Mycobacterium leprae Probable two-component sensor kinase 0.0015 0.0056 0.0069
Echinococcus granulosus voltage gated potassium channel 0.0014 0.0035 0.0037
Trypanosoma cruzi serine peptidase, putative 0.0026 0.0182 0.0341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.032 0.075
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0032 0.0062
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.0252 0.0297
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0014 0.0035 0.0037
Brugia malayi hypothetical protein 0.0016 0.0066 0.0116
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0053 0.0508 0.0965
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0039 0.0339 0.0399
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.017 0.0392
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0336 0.0635
Echinococcus granulosus dnaJ subfamily B 0.043 0.4982 0.5865
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0015 0.0051 0.0087
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0035 0.0037
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0035 0.0042
Mycobacterium ulcerans dehydrogenase 0.0053 0.0508 0.1452
Echinococcus multilocularis thyroid hormone receptor alpha 0.0164 0.1825 0.1821
Onchocerca volvulus 0.0032 0.0252 0.0871
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0199 0.0382
Echinococcus multilocularis serotonin transporter 0.0095 0.1006 0.1002
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0172 0.1913 0.3666
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0078 0.0092
Entamoeba histolytica hypothetical protein 0.0038 0.0323 0.0909
Plasmodium falciparum endoplasmin, putative 0.0015 0.0056 0.0098
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.052 0.0989
Entamoeba histolytica hypothetical protein 0.0026 0.0182 0.0513
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0096 0.0175
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0053 0.0508 0.0965
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0039 0.0339 0.064
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0189 0.0353
Trypanosoma cruzi serine peptidase, putative 0.0026 0.0182 0.0341
Entamoeba histolytica P-glyco protein 6, putative 0.0011 0.0006 0.0016
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0335 0.0634
Loa Loa (eye worm) hypothetical protein 0.0021 0.0121 0.022
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0232 0.0422
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0053 0.0508 0.1351
Echinococcus granulosus lamin dm0 0.0028 0.0211 0.0243
Trypanosoma brucei DNA polymerase IV, putative 0.0063 0.0628 0.1195
Mycobacterium tuberculosis Probable oxidoreductase 0.0012 0.0013 0.0014
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0128 0.1399 0.1395
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.017 0.0477
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0128 0.1399 0.1643
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0307 0.3524 0.9913
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0026 0.0182 0.0341
Toxoplasma gondii hypothetical protein 0.0016 0.0066 0.0127
Schistosoma mansoni hypothetical protein 0.0038 0.0323 0.0381
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0323 0.061
Onchocerca volvulus 0.0016 0.0063 0.0201
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0019 0.0096 0.0109
Loa Loa (eye worm) hypothetical protein 0.0157 0.1739 0.3157
Brugia malayi cation channel family protein 0.0014 0.0035 0.0058
Entamoeba histolytica P-glycoprotein-5 0.0011 0.0006 0.0016
Schistosoma mansoni terminal deoxycytidyl transferase 0.0036 0.0296 0.0348
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0066 0.0127
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0053 0.0508 0.0965
Echinococcus granulosus microtubule associated protein 2 0.0726 0.8491 1
Echinococcus granulosus sex peptide receptor 0.0039 0.0339 0.0394
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0047 0.0427 0.0502
Plasmodium vivax PST-A protein 0.0026 0.0182 0.035
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0435 0.0826
Mycobacterium ulcerans lysophospholipase 0.0303 0.3466 1
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0199 0.0373
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.0252 0.0248
Chlamydia trachomatis DNA gyrase subunit A 0.0063 0.0626 0.275
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0053 0.0508 0.0965
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0121 0.0117
Trypanosoma brucei DNA polymerase IV, putative 0.0057 0.0545 0.1037
Trypanosoma brucei heat shock protein, putative 0.0015 0.0056 0.0098
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0638 0.1831
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0182 0.0422
Loa Loa (eye worm) hypothetical protein 0.0047 0.0427 0.0774
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0064
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Loa Loa (eye worm) hypothetical protein 0.0032 0.0254 0.0462
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0035 0.0042
Plasmodium falciparum transporter, putative 0.0016 0.0066 0.0118
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0435 0.079
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0012 0.0013 0.0033
Onchocerca volvulus 0.0039 0.0339 0.1176
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0081 0.0831 0.1593
Echinococcus multilocularis rho GTPase activating protein 20 0.0016 0.0063 0.0058
Loa Loa (eye worm) nuclear hormone receptor 0.0015 0.0052 0.0095
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0339 0.0394
Schistosoma mansoni protein phosphatase 2C 0.0016 0.007 0.0082
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0037 0.0033
Loa Loa (eye worm) hypothetical protein 0.0276 0.3145 0.5708
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0121 0.0224
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0199 0.2237 0.7868
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0336 0.0944
Echinococcus granulosus calcium activated potassium channel 0.0014 0.0041 0.0044
Chlamydia trachomatis thioredoxin reductase 0.0053 0.0508 0.2226
Schistosoma mansoni polycystin 1-related 0.0021 0.012 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0426 0.1003
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.0252 0.0474
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0172 0.1913 0.5428
Leishmania major DNA topoisomerase III, putative 0.0016 0.0063 0.0111
Brugia malayi tailless protein 0.0015 0.0052 0.009
Schistosoma mansoni intermediate filament proteins 0.0028 0.0211 0.0248
Echinococcus granulosus sodium and chloride dependent glycine 0.0016 0.0066 0.0073
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0062 0.011
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0632 0.1812
Trichomonas vaginalis set domain proteins, putative 0.025 0.284 0.6755
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0015 0.0051 0.0133
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0035 0.0037
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0015 0.0051 0.0133
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0006 0.0001
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.051 0.097
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0435 0.0826
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0016 0.0063 0.0136
Toxoplasma gondii heat shock protein 90, putative 0.0015 0.0056 0.0107
Echinococcus granulosus sodium channel protein 0.0051 0.0474 0.0553
Mycobacterium ulcerans hypothetical protein 0.0303 0.3466 1
Echinococcus granulosus two pore calcium channel protein 2 0.0014 0.0035 0.0037
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.017 0.0317
Entamoeba histolytica disulphide oxidoreductase, putative 0.0053 0.0508 0.1428
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Echinococcus granulosus multidrug resistance protein 1 0.0011 0.0006 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0032 0.0062
Entamoeba histolytica heat shock protein 90, putative 0.0015 0.0056 0.0158
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0096 0.0109
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0201 0.2261 0.6518
Plasmodium falciparum esterase, putative 0.0303 0.3466 0.6641
Trypanosoma cruzi DNA polymerase eta, putative 0.0036 0.0296 0.0558
Brugia malayi jmjC domain containing protein 0.0016 0.007 0.0123
Brugia malayi Dopamine receptor protein 2 0.0039 0.0339 0.064
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0035 0.0042
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0335 0.0642
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.0252 0.0871
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.007 0.0127
Leishmania major hypothetical protein, conserved 0.0016 0.007 0.0125
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0012 0.0013 0.0024
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0021 0.0121 0.0138
Plasmodium vivax multidrug resistance protein 1, putative 0.0011 0.0006 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0378 0.0716
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0026 0.0182 0.0422
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0053 0.0508 0.0963
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0074 0.0087
Plasmodium falciparum lysophospholipase, putative 0.0303 0.3466 0.6641
Echinococcus multilocularis voltage gated potassium channel 0.0022 0.0139 0.0135
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0019 0.0096 0.0092
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.0252 0.0474
Leishmania major heat shock protein 83-1 0.0015 0.0056 0.0098
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0018 0.0087 0.0167
Brugia malayi glutamate synthase 0.0053 0.0508 0.0963
Brugia malayi PAS domain containing protein 0.0051 0.0481 0.0913
Loa Loa (eye worm) heat shock protein 90 0.0015 0.0056 0.0102
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.012
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0021 0.0121 0.0138
Echinococcus granulosus sodium leak channel non selective protein 0.0014 0.0035 0.0037
Onchocerca volvulus 0.0052 0.0491 0.1714
Trypanosoma brucei cytochrome P450, putative 0.0024 0.016 0.0298
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0254 0.03
Brugia malayi Transient-receptor-potential like protein 0.0014 0.0035 0.0058
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0016 0.0066 0.012
Echinococcus multilocularis short transient receptor potential channel 6 0.0014 0.0035 0.0031
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0095 0.1006 0.1185
Schistosoma mansoni hypothetical protein 0.0039 0.0339 0.0399
Plasmodium falciparum glutathione reductase 0.045 0.5217 1
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0062 0.0058
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0014 0.0035 0.0042
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0053 0.0508 0.0963
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0015 0.0056 0.012
Echinococcus granulosus cpg binding protein 0.0032 0.0253 0.0293
Loa Loa (eye worm) hypothetical protein 0.012 0.1296 0.2352
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0039 0.0339 0.0615
Echinococcus granulosus heat shock protein 90 0.0015 0.0056 0.0061
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0294 0.337 0.3368
Schistosoma mansoni 60S ribosomal protein L21 0.0017 0.0078 0.0092
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0035 0.0037
Entamoeba histolytica thioredoxin reductase, putative 0.0053 0.0508 0.1428
Schistosoma mansoni cpg binding protein 0.003 0.0232 0.0274
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0335 0.039
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.007 0.0066
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0015 0.0051 0.0133
Loa Loa (eye worm) hypothetical protein 0.0199 0.224 0.4066
Loa Loa (eye worm) hypothetical protein 0.0032 0.0252 0.0458
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0077 0.0782 0.2131
Trypanosoma cruzi DNA polymerase kappa, putative 0.0063 0.0628 0.1195
Onchocerca volvulus 0.0039 0.0339 0.1176
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0096 0.0092
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0201 0.2261 0.4328
Trypanosoma cruzi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0017 0.0078 0.014
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.017 0.0315
Trypanosoma brucei DNA topoisomerase IA, putative 0.0016 0.0063 0.0111
Echinococcus multilocularis musashi 0.0028 0.0211 0.0207
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0339 0.0394
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0035 0.0068
Trypanosoma brucei Serine peptidase, Clan SC, Family S09X 0.0026 0.0182 0.0341
Brugia malayi hypothetical protein 0.0039 0.0339 0.064
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0335 0.0634
Trichomonas vaginalis Ferredoxin 6 0.0012 0.0013 0.0018
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0335 0.0943
Echinococcus granulosus hypothetical protein 0.0039 0.0339 0.0394
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.0032 0.0062
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0096 0.0109
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0016 0.0066 0.0062
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0148 0.1627 0.3112
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0032 0.0028
Schistosoma mansoni neuroligin 3 (S09 family) 0.0047 0.0427 0.0502
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0339 0.0335
Loa Loa (eye worm) hypothetical protein 0.0095 0.1006 0.1826
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0035 0.0042
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0012 0.0013 0.0014
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0109 0.0199
Trypanosoma brucei heat shock protein, putative 0.0015 0.0056 0.0098
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Brugia malayi Pre-SET motif family protein 0.022 0.2481 0.4749
Schistosoma mansoni myosin xvIII 0.0039 0.0339 0.0399
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0014 0.0035 0.0037
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0199 0.2237 0.7868
Echinococcus multilocularis 0.0015 0.0051 0.0047
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0303 0.3466 0.8248
Loa Loa (eye worm) hypothetical protein 0.0015 0.0052 0.0095
Toxoplasma gondii exonuclease III APE 0.002 0.0109 0.0208
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0406 0.0778
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0053 0.0508 0.1452
Echinococcus multilocularis G-protein coupled receptor, putative 0.0039 0.0339 0.0335
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0339 0.0399
Loa Loa (eye worm) hypothetical protein 0.0013 0.003 0.0055
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0039 0.0339 0.0615
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0039 0.0339 0.064
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0015 0.0051 0.0133
Loa Loa (eye worm) hypothetical protein 0.0026 0.0182 0.0331
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0062 0.011
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0426 0.1003
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0632 0.0744
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0035 0.0068
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0052 0.0048
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0036 0.0296 0.0348
Echinococcus multilocularis serotonin receptor 0.0039 0.0339 0.0335
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0201 0.2261 0.4329
Trypanosoma brucei heat shock protein, putative 0.0015 0.0056 0.0098
Brugia malayi nuclear receptor NHR-88 0.0032 0.0252 0.0474
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.017 0.0477
Echinococcus multilocularis sex peptide receptor 0.0039 0.0339 0.0335
Loa Loa (eye worm) hypothetical protein 0.0015 0.0053 0.0097
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0337 0.0637
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0015 0.0051 0.0133
Onchocerca volvulus 0.0043 0.0388 0.135
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0016 0.0066 0.0116
Loa Loa (eye worm) hypothetical protein 0.0028 0.0211 0.0382
Echinococcus granulosus allatostatin A receptor 0.0039 0.0339 0.0394
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0035 0.0031
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0123 0.1335 0.3843
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0035 0.0037
Loa Loa (eye worm) hypothetical protein 0.0047 0.0427 0.0774
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0015 0.0056 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0291 0.0681
Brugia malayi neuropeptide F receptor 0.0039 0.0339 0.064
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0254 0.03
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0039 0.0339 0.0399
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0053 0.0508 0.0965
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.3524 0.8385
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0247 0.0465
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0062 0.0068
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0126 0.023
Plasmodium falciparum flap endonuclease 1 0.0027 0.0199 0.0373
Loa Loa (eye worm) hypothetical protein 0.0015 0.0052 0.0095
Brugia malayi Cytochrome P450 family protein 0.0024 0.016 0.0296
Onchocerca volvulus 0.0032 0.0254 0.0878
Echinococcus multilocularis para nitrobenzyl esterase 0.0047 0.0427 0.0423
Loa Loa (eye worm) hypothetical protein 0.0039 0.0337 0.0611
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0201 0.2261 0.2659
Schistosoma mansoni neuropeptide receptor 0.0039 0.0339 0.0399
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0064
Schistosoma mansoni opsin-like receptor 0.0039 0.0339 0.0399
Mycobacterium ulcerans carboxylesterase, LipT 0.0047 0.0427 0.1219
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0053 0.0508 0.1452
Brugia malayi cytochrome P450 0.0015 0.0051 0.0087
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0062 0.0608 0.0712
Echinococcus multilocularis RUN 0.0021 0.012 0.0116
Schistosoma mansoni lipoxygenase 0.0124 0.1347 0.1586
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0071 0.0127
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0364 0.4201 1
Schistosoma mansoni heat shock protein 0.0015 0.0056 0.0066
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0015 0.0051 0.0133
Treponema pallidum NADH oxidase 0.0201 0.2261 0.6417
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0035 0.0042
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0012 0.0013 0.0024
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0335 0.0634
Echinococcus multilocularis neuropeptide Y receptor 0.0039 0.0339 0.0335
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0039 0.0339 0.0335
Loa Loa (eye worm) hypothetical protein 0.0015 0.0052 0.0095
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0039 0.0339 0.0394
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0362 0.1015
Entamoeba histolytica 2,3-bisphosphoglycerate-independentphosphoglycerate mutase, putative 0.0058 0.0561 0.1578
Mycobacterium ulcerans oxygenase 0.0012 0.0013 0.0024
Schistosoma mansoni amine GPCR 0.0039 0.0339 0.0399
Loa Loa (eye worm) hypothetical protein 0.0047 0.0427 0.0774
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0039 0.0339 0.0394
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0339 0.0399
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0053 0.0508 0.0973
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0189 0.0353
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.0252 0.0458
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0643
Trypanosoma brucei DNA polymerase kappa, putative 0.0063 0.0628 0.1195
Schistosoma mansoni sodium/chloride dependent transporter 0.0017 0.0072 0.0085
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0096 0.0092
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.045 0.5217 1
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0182 0.0422
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0035 0.0037
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0039 0.0339 0.0335
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0014 0.0035 0.0037
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0071 0.0126
Echinococcus granulosus tumor protein p63 0.0355 0.4093 0.4818
Brugia malayi G-protein coupled receptor 0.0039 0.0339 0.064
Trichomonas vaginalis spcc417.12 protein, putative 0.0047 0.0427 0.1003
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0047 0.0427 0.0808
Echinococcus granulosus neuropeptide FF receptor 2 0.0039 0.0339 0.0394
Trypanosoma cruzi heat shock protein 85, putative 0.0015 0.0056 0.0098
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0014 0.0035 0.0106
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0053 0.0508 0.0921
Chlamydia trachomatis DNA topoisomerase I 0.0016 0.0063 0.0253
Brugia malayi orphan nuclear receptor NR2E1 0.0015 0.0052 0.009
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0643
Plasmodium falciparum DNA gyrase subunit A 0.0063 0.0626 0.1192
Trypanosoma brucei protein kinase, putative 0.0054 0.051 0.097
Trichomonas vaginalis DNA polymerase eta, putative 0.0063 0.0628 0.1483
Schistosoma mansoni single-minded 0.0051 0.0481 0.0567
Schistosoma mansoni hypothetical protein 0.0012 0.0015 0.0018
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0126 0.023
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0053 0.0508 0.0965
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0064
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0201 0.2261 0.6518
Leishmania major DNA topoisomerase ii 0.0279 0.3182 0.6095
Entamoeba histolytica hypothetical protein 0.0038 0.0323 0.0909
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0012 0.0013 0.0014
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0053 0.0049
Schistosoma mansoni glutamate synthase 0.0053 0.0508 0.0598
Mycobacterium tuberculosis Conserved hypothetical protein 0.0167 0.186 0.3559
Mycobacterium tuberculosis Conserved hypothetical protein 0.0036 0.0296 0.0557
Trypanosoma brucei unspecified product 0.0024 0.0165 0.0307
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0406 0.0778
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0032 0.0052
Toxoplasma gondii peptidase S15, putative 0.0026 0.0182 0.035
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.0252 0.0474
Mycobacterium ulcerans epimerase 0.0021 0.0126 0.0349
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0006 0.0001
Loa Loa (eye worm) glutathione reductase 0.045 0.5217 0.947
Mycobacterium tuberculosis Possible lysophospholipase 0.0303 0.3466 0.6641
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0182 0.0422
Echinococcus granulosus Ankyrin 0.0015 0.0055 0.006
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0632 0.0744
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0054 0.0094
Wolbachia endosymbiont of Brugia malayi phosphoglyceromutase 0.0105 0.1121 0.4929
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0139 0.0258
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0083 0.0149
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.007 0.0082
Loa Loa (eye worm) nuclear receptor NHR-67 0.0015 0.0052 0.0095
Mycobacterium ulcerans electron transfer protein FdxB 0.0012 0.0013 0.0024
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0015 0.0056 0.0148
Echinococcus multilocularis lysine specific demethylase 5A 0.0062 0.0608 0.0604
Mycobacterium tuberculosis Probable dehydrogenase 0.0162 0.18 0.3444
Schistosoma mansoni aryl hydrocarbon receptor 0.0051 0.0481 0.0567
Echinococcus granulosus multidrug resistance protein 1 0.0011 0.0006 0.0002
Schistosoma mansoni transient receptor potential channel 0.0014 0.0035 0.0042
Leishmania major heat shock protein 83-1 0.0015 0.0056 0.0098
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.012
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0032 0.0062
Toxoplasma gondii DNA topoisomerase 2, putative 0.0294 0.337 0.646
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0053 0.0058
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0053 0.0508 0.1196
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0026 0.0182 0.0422
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0632 0.1212
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0121 0.0233
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0189 0.0362
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0016 0.0063 0.0136
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0015 0.0056 0.0148
Trypanosoma cruzi metacaspase, putative 0.0047 0.0426 0.0809
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0016 0.0066 0.0078
Schistosoma mansoni voltage-gated ion channel 0.0014 0.0035 0.0042
Brugia malayi hypothetical protein 0.0015 0.0052 0.009
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0014 0.0035 0.0042
Loa Loa (eye worm) acetylcholinesterase 1 0.0276 0.3145 0.5708
Leishmania major heat shock protein 83-1 0.0015 0.0056 0.0098
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Schistosoma mansoni sodium/chloride dependent transporter 0.0095 0.1006 0.1185
Plasmodium vivax thioredoxin reductase, putative 0.045 0.5217 1
Echinococcus multilocularis caspase 8 0.0047 0.0426 0.0422
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0121 0.0224
Schistosoma mansoni loxhd1 0.0021 0.012 0.0141
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0176 0.0407
Giardia lamblia DNA topoisomerase III 0.0016 0.0063 0.0164
Toxoplasma gondii hypothetical protein 0.0026 0.0182 0.035
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0026 0.0182 0.0341
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0287 0.0724
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0035 0.0031
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0006 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0015 0.0051 0.0087
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0109 0.0198
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0015 0.0051 0.0087
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0109 0.0295
Giardia lamblia Thioredoxin reductase 0.0053 0.0508 0.1429
Brugia malayi hypothetical protein 0.0039 0.0339 0.064
Trichomonas vaginalis conserved hypothetical protein 0.0303 0.3466 0.8248
Echinococcus multilocularis apoptotic protease activating factor 1 0.0043 0.0388 0.0384
Onchocerca volvulus 0.0039 0.0339 0.1176
Giardia lamblia Glutamate synthase 0.0053 0.0508 0.1429
Loa Loa (eye worm) hypothetical protein 0.0025 0.017 0.0308
Echinococcus granulosus monoacylglycerol lipase abhd12 0.0026 0.0182 0.021
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0337 0.0637
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0128 0.1399 0.1395
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0426 0.1003
Echinococcus granulosus potassium large conductance calcium activated 0.0014 0.0035 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0247 0.0465
Entamoeba histolytica hypothetical protein 0.0026 0.0182 0.0513
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0035 0.0037
Leishmania major heat shock protein 83-1 0.0015 0.0056 0.0098
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.016 0.029
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.0426 0.0817
Schistosoma mansoni microtubule-associated protein tau 0.0726 0.8491 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0039 0.0339 0.0394
Brugia malayi ecdysone receptor 0.0015 0.0052 0.009
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0252 0.0474
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0053 0.0508 0.1351
Mycobacterium leprae Probable two component sensor kinase MprB 0.0015 0.0056 0.0069
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.007 0.0134
Mycobacterium tuberculosis Conserved hypothetical protein 0.0026 0.0182 0.0339
Leishmania major DNA polymerase eta, putative 0.0036 0.0296 0.0558
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0052 0.0166
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0201 0.2261 0.4329
Mycobacterium tuberculosis Conserved protein 0.0015 0.0056 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.032 0.075
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0016 0.0066 0.0078
Brugia malayi heat shock protein 90 0.0015 0.0056 0.0097
Trypanosoma brucei DNA polymerase IV, putative 0.0063 0.0628 0.1195
Leishmania major ferredoxin 2fe-2s-like protein 0.0012 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.012
Echinococcus multilocularis nuclear receptor nhr 48 0.0015 0.0052 0.0048
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.005 0.0466 0.0462
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0016 0.0066 0.0078
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0014 0.0035 0.0042
Loa Loa (eye worm) carboxylesterase 0.0047 0.0427 0.0774
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0199 0.0461
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0339 0.0335
Loa Loa (eye worm) hypothetical protein 0.0017 0.0074 0.0134
Trichomonas vaginalis glutamate synthase, putative 0.0053 0.0508 0.1196
Trypanosoma brucei unspecified product 0.0024 0.0165 0.0307
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0015 0.0052 0.0062
Brugia malayi Cytochrome P450 family protein 0.0015 0.0051 0.0087
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0071 0.0136
Leishmania major hypothetical protein, conserved 0.0015 0.0056 0.0098
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0336 0.0391
Loa Loa (eye worm) hypothetical protein 0.0014 0.0037 0.0067
Plasmodium vivax PST-A protein 0.0026 0.0182 0.035
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0032 0.0062
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0039 0.0339 0.0615
Entamoeba histolytica heat shock protein 90, putative 0.0015 0.0056 0.0158
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0035 0.0031
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0039 0.0339 0.0399
Loa Loa (eye worm) DNA topoisomerase III 0.0016 0.0063 0.0113
Brugia malayi Cytochrome P450 family protein 0.0035 0.0289 0.0544
Echinococcus granulosus somatostatin receptor 0.0039 0.0339 0.0394
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.007 0.0125
Schistosoma mansoni hypothetical protein 0.0178 0.199 0.2343
Echinococcus multilocularis serotonin receptor 0.0039 0.0339 0.0335
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0173
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0026 0.0182 0.0341
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0172 0.1914 0.3662
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0053 0.0508 0.1428
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.0252 0.0293
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0021 0.0121 0.0117
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0039 0.0339 0.0394
Brugia malayi ImpB/MucB/SamB family protein 0.0036 0.0296 0.0557
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0026 0.0182 0.0422
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0053 0.0508 0.0965
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0331 0.3798 0.7278
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0121 0.0233
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0012 0.0013 0.0024
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0426 0.1003
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0014 0.0035 0.0042
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0053 0.0508 0.0504
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0053 0.0508 0.0973
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0291 0.0681
Plasmodium falciparum lysophospholipase, putative 0.0026 0.0182 0.0341
Brugia malayi Protein C20orf22 0.0026 0.0182 0.0339
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0252 0.0474
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0053 0.0508 0.0973
Loa Loa (eye worm) hypothetical protein 0.0334 0.3835 0.6962
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0039 0.0339 0.0399
Trypanosoma cruzi trypanothione reductase, putative 0.045 0.5217 1
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0291 0.0558
Echinococcus granulosus voltage dependent calcium channel 0.0128 0.1399 0.1643
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0096 0.0113
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0252 0.0474
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0095 0.0397
Chlamydia trachomatis endonuclease IV 0.0081 0.0831 0.366
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0201 0.2261 0.4328
Trypanosoma brucei NADH dehydrogenase 0.0053 0.0508 0.0965
Trypanosoma brucei Heat shock protein 83, putative 0.0015 0.0056 0.0098
Trypanosoma cruzi Serine peptidase, Clan SC, Family S09X, putative 0.0026 0.0182 0.0341
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0039 0.0339 0.064
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0013 0.0016
Brugia malayi MGC79044 protein 0.0026 0.0182 0.0339
Loa Loa (eye worm) carboxylesterase 0.0047 0.0427 0.0774
Toxoplasma gondii endonuclease IV APN 0.0081 0.0831 0.1593
Trypanosoma brucei heat shock protein, putative 0.0015 0.0056 0.0098
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0015 0.0051 0.0087
Giardia lamblia Fructose-bisphosphate aldolase 0.0307 0.3524 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0074 0.0134
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0071 0.0126
Brugia malayi Cytochrome P450 family protein 0.0024 0.016 0.0296
Schistosoma mansoni transient receptor potential channel 0.0014 0.0037 0.0044
Loa Loa (eye worm) TOPoisomerase family member 0.0294 0.337 0.6117
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0339 0.0399
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.051 0.0596
Onchocerca volvulus 0.0015 0.0052 0.0166
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0014 0.0035 0.0042
Leishmania major heat shock protein 83-1 0.0015 0.0056 0.0098
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0035 0.0042
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0303 0.3466 0.9752
Brugia malayi nuclear receptor NHR-88 0.0015 0.0052 0.009
Entamoeba histolytica hypothetical protein 0.0038 0.0323 0.0909
Echinococcus granulosus voltage gated hydrogen channel 1 0.0014 0.0035 0.0037
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0109 0.0306
Brugia malayi G protein-coupled receptor 0.0039 0.0339 0.064
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0014 0.0035 0.0058
Mycobacterium ulcerans hypothetical protein 0.0053 0.0508 0.1452
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0339 0.0335
Schistosoma mansoni DNA polymerase eta 0.0036 0.0296 0.0348
Trypanosoma brucei DNA topoisomerase III, putative 0.0016 0.0063 0.0111
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0252 0.0293
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0096 0.0216
Echinococcus granulosus neuropeptide Y receptor 0.0039 0.0339 0.0394
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0015 0.0051 0.0133
Brugia malayi jmjC domain containing protein 0.0016 0.007 0.0123
Leishmania major hypothetical protein, conserved 0.0027 0.0189 0.0353
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0632 0.1202
Echinococcus multilocularis carboxylesterase 5A 0.0276 0.3145 0.3142
Plasmodium vivax DNA gyrase subunit A, putative 0.0063 0.0626 0.12
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0121 0.0276
Echinococcus granulosus serotonin receptor 0.0039 0.0339 0.0394
Brugia malayi MAP kinase sur-1 0.0054 0.051 0.0968
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0015 0.0056 0.0148
Echinococcus granulosus acetylcholinesterase 0.0276 0.3145 0.3701
Onchocerca volvulus 0.003 0.0232 0.08
Brugia malayi hypothetical protein 0.0039 0.0339 0.064
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0063 0.0628 0.1483
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0199 0.0195
Trypanosoma brucei metacaspase 0.0047 0.0426 0.0809
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0211 0.0382
Loa Loa (eye worm) voltage-gated calcium channel 0.0014 0.0035 0.0064
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0053 0.0508 0.1196
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.022 0.2481 0.4503
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0071 0.0127
Trichomonas vaginalis heat shock protein, putative 0.0015 0.0056 0.012
Entamoeba histolytica DNA topoisomerase III, putative 0.0016 0.0063 0.0176
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.0252 0.0474
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0052 0.0062
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.0252 0.0458
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0063 0.0626 0.1776
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Loa Loa (eye worm) hypothetical protein 0.0015 0.0052 0.0095
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0353 0.0828
Trypanosoma cruzi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0105 0.1121 0.2142
Schistosoma mansoni multidrug resistance protein 0.0011 0.0006 0.0007
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0053 0.0508 0.0965
Plasmodium vivax DNA topoisomerase 3, putative 0.0016 0.0063 0.012
Onchocerca volvulus 0.0047 0.0427 0.1485
Treponema pallidum oxidoreductase 0.0053 0.0508 0.144
Schistosoma mansoni caspase-7 (C14 family) 0.009 0.0941 0.1108
Trichomonas vaginalis Ferredoxin 4 0.0012 0.0013 0.0018
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0016 0.0066 0.0073
Trypanosoma brucei heat shock protein, putative 0.0015 0.0056 0.0098
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Leishmania major hypothetical protein, conserved 0.0026 0.0182 0.0341
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0199 0.0373
Loa Loa (eye worm) hypothetical protein 0.0015 0.0052 0.0095
Echinococcus multilocularis cpg binding protein 0.0032 0.0253 0.0249
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.007 0.0127
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0071 0.0136
Trypanosoma cruzi metacaspase, putative 0.0047 0.0426 0.0809
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0254 0.025
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0053 0.0508 0.1452
Brugia malayi hypothetical protein 0.0014 0.0035 0.0058
Loa Loa (eye worm) hypoxia-induced factor 1 0.0158 0.1754 0.3184
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0206 0.0477
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0012 0.0013 0.0016
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0015 0.0051 0.0133
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0052 0.0057
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0076 0.0772 0.1472
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0039 0.0339 0.0394
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0435 0.0824
Loa Loa (eye worm) hypothetical protein 0.0047 0.0427 0.0774
Loa Loa (eye worm) hypothetical protein 0.0017 0.0074 0.0134
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.051 0.0926
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0.0035 0.0042
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0053 0.0508 0.1428
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.0793 0.079
Brugia malayi hypothetical protein 0.0017 0.0077 0.0137
Echinococcus multilocularis dro:myosuppressin receptor 0.0039 0.0339 0.0335
Trichomonas vaginalis mercuric reductase, putative 0.0201 0.2261 0.5376
Echinococcus granulosus thyroid hormone receptor alpha 0.0015 0.0052 0.0057
Onchocerca volvulus 0.0039 0.0339 0.1176
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0015 0.0056 0.0107
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0096 0.0216
Chlamydia trachomatis DNA gyrase subunit A 0.0063 0.0626 0.275
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0014 0.0035 0.0058
Plasmodium falciparum BEM46-like protein, putative 0.0026 0.0182 0.0341
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0201 0.2261 1
Onchocerca volvulus 0.0021 0.012 0.0404
Mycobacterium ulcerans DNA gyrase subunit A 0.0063 0.0626 0.1794
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0052 0.009
Trypanosoma cruzi monoglyceride lipase, putative 0.0303 0.3466 0.6641
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0323 0.0921
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0294 0.337 0.6456
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0303 0.3466 0.8248
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0062 0.011
Echinococcus multilocularis sodium channel protein 0.0051 0.0474 0.047
Echinococcus granulosus tm gpcr rhodopsin 0.0039 0.0339 0.0394
Brugia malayi hypothetical protein 0.0021 0.012 0.022
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0109 0.0199
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0053 0.0508 0.0963
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0015 0.0056 0.0098
Schistosoma mansoni heat shock protein 0.0015 0.0056 0.0066
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0173
Trypanosoma brucei heat shock protein 90, putative 0.0015 0.0056 0.0098
Trichomonas vaginalis endoplasmin, putative 0.0015 0.0056 0.012
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0011 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.001
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0201 0.2261 0.4329
Brugia malayi Flap endonuclease-1 0.0027 0.0199 0.0371
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0014 0.0035 0.0058
Plasmodium vivax DNA topoisomerase II, putative 0.0294 0.337 0.646
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0362 0.1018
Loa Loa (eye worm) hypothetical protein 0.0081 0.0831 0.1508
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0173
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0052 0.0057
Echinococcus granulosus two pore calcium channel protein 1 0.0014 0.0035 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0209 0.0485
Echinococcus multilocularis Phospholipase carboxylesterase 0.0026 0.0182 0.0178
Echinococcus granulosus g protein coupled receptor 0.0039 0.0339 0.0394
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0201 0.2261 0.4329
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0172 0.1914 0.5516
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0014 0.0035 0.0031
Echinococcus granulosus carboxylesterase 5A 0.0276 0.3145 0.3701
Echinococcus multilocularis caspase 2 0.009 0.0941 0.0937
Trypanosoma brucei unspecified product 0.0057 0.0545 0.1037
Brugia malayi acetyltransferase, GNAT family protein 0.0152 0.1684 0.322
Schistosoma mansoni neuropeptide receptor 0.0039 0.0339 0.0399
Brugia malayi olfactory channel protein osm-9 0.0014 0.0037 0.006
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0015 0.0051 0.0133
Onchocerca volvulus Neuropeptide F receptor homolog 0.0039 0.0339 0.1176
Trypanosoma cruzi adrenodoxin precursor, putative 0.0012 0.0013 0.0016
Echinococcus multilocularis heat shock protein 90 0.0015 0.0056 0.0052
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0035 0.0031
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0096 0.0113
Schistosoma mansoni two-pore calcium channel 0.0014 0.0035 0.0042
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0014 0.0035 0.0042
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0241 0.274 0.7903
Schistosoma mansoni peptidase 0.0026 0.0182 0.0215
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0074 0.0131
Onchocerca volvulus 0.0012 0.0013 0.0026
Onchocerca volvulus 0.0047 0.0427 0.1485
Loa Loa (eye worm) hypothetical protein 0.0095 0.1006 0.1826
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0016 0.0066 0.0127
Trichomonas vaginalis glutamate synthase, putative 0.0053 0.0508 0.1196
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.015 0.1659 0.3173
Echinococcus granulosus neuropeptide receptor A26 0.0523 0.6084 0.7163
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0611 0.1172
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0304 0.0712
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0331 0.3798 0.7278
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0426 0.1003
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.012
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0047 0.0427 0.0498
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0039 0.0339 0.064
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0132 0.1446 0.1442
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.0252 0.0297
Onchocerca volvulus 0.0016 0.0066 0.0214
Chlamydia trachomatis DNA gyrase subunit B 0.0136 0.1485 0.6558
Schistosoma mansoni hypothetical protein 0.0043 0.0388 0.0457
Trypanosoma brucei DNA polymerase kappa, putative 0.0063 0.0628 0.1195
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0039 0.0339 0.0335
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0254 0.0488
Echinococcus multilocularis potassium voltage gated channel protein 0.0014 0.0035 0.0031
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0287 0.054
Brugia malayi GRF zinc finger family protein 0.0016 0.0063 0.0109
Schistosoma mansoni calcium-activated potassium channel 0.0014 0.0035 0.0042
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0128 0.1399 0.2673
Trypanosoma brucei DNA polymerase kappa, putative 0.0063 0.0628 0.1195
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0064
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0339 0.0335
Trichomonas vaginalis DNA topoisomerase II, putative 0.0294 0.337 0.8019
Echinococcus granulosus heat shock protein 0.0015 0.0056 0.0061
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0035 0.0037
Leishmania major hypothetical protein, conserved 0.0014 0.0035 0.0059
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0016 0.0066 0.0116
Onchocerca volvulus 0.0039 0.0339 0.1176
Echinococcus granulosus voltage dependent calcium channel 0.0076 0.0772 0.0905
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0039 0.0339 0.0399
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0247 0.0465
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0335 0.0634
Treponema pallidum hypothetical protein 0.0059 0.0577 0.1638
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.007 0.0125
Mycobacterium ulcerans hypothetical protein 0.0059 0.0577 0.1654
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0096 0.0113
Onchocerca volvulus 0.025 0.2841 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0201 0.2261 0.4334
Schistosoma mansoni histamine h1 receptor 0.0039 0.0339 0.0399
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Giardia lamblia NADH oxidase lateral transfer candidate 0.0201 0.2261 0.6412
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.0252 0.0293
Echinococcus granulosus Phospholipase carboxylesterase 0.0026 0.0182 0.021
Mycobacterium ulcerans ferredoxin reductase 0.0053 0.0508 0.1452
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.051 0.097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.032 0.075
Brugia malayi nuclear hormone receptor 0.0015 0.0052 0.009
Echinococcus multilocularis voltage dependent calcium channel 0.0128 0.1399 0.1395
Echinococcus granulosus biogenic amine 5HT receptor 0.0039 0.0339 0.0394
Toxoplasma gondii hypothetical protein 0.0026 0.0182 0.035
Mycobacterium tuberculosis Probable two component sensor kinase 0.0015 0.0056 0.0097
Schistosoma mansoni hypothetical protein 0.0109 0.1166 0.1373
Plasmodium falciparum alpha/beta hydrolase, putative 0.0026 0.0182 0.0341
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0015 0.0056 0.0148
Brugia malayi MGC83647 protein 0.0026 0.0182 0.0339
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0083 0.0149
Plasmodium vivax alpha/beta hydrolase, putative 0.0026 0.0182 0.035
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0339 0.0399
Schistosoma mansoni hypothetical protein 0.0039 0.0339 0.0399
Echinococcus multilocularis calcium activated potassium channel 0.0014 0.0041 0.0037
Loa Loa (eye worm) hypothetical protein 0.0032 0.0252 0.0458
Schistosoma mansoni phd/f-box containing protein 0.0016 0.007 0.0082
Brugia malayi nuclear hormone receptor 0.0032 0.0252 0.0474
Toxoplasma gondii esterase/lipase/thioesterase domain-containing protein 0.0026 0.0182 0.035
Toxoplasma gondii DNA topoisomerase family protein 0.0016 0.0063 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0032 0.0062
Trypanosoma cruzi metacaspase 5, putative 0.0047 0.0426 0.0809
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0014 0.0035 0.0042
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0035 0.0042
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0015 0.0051 0.0088
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.012 0.0116
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0426 0.1003
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0006 0.0001
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0132 0.1446 0.1699
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.031 0.3554 0.6808
Schistosoma mansoni sodium-dependent amino acid transporter 0.0016 0.0066 0.0078
Schistosoma mansoni amine GPCR 0.0562 0.6543 0.7706
Trypanosoma brucei heat shock protein, putative 0.0015 0.0056 0.0098
Brugia malayi STAT protein, DNA binding domain containing protein 0.0138 0.1516 0.2899
Toxoplasma gondii selenide, water dikinase 0.0053 0.0508 0.0973
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0206 0.0477
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0109 0.0123
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0071 0.0129
Brugia malayi AMP-binding enzyme family protein 0.0025 0.017 0.0315
Echinococcus granulosus folate receptor beta 0.0108 0.1152 0.1353
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0053 0.0508 0.0504
Brugia malayi ORL1-like opioid receptor 0.0039 0.0339 0.064
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0053 0.0508 0.0963
Echinococcus granulosus biogenic amine 5HT receptor 0.0039 0.0339 0.0394
Schistosoma mansoni neuropeptide F-like receptor 0.0039 0.0339 0.0399
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0053 0.0508 0.1428
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0053 0.0508 0.1196
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0294 0.337 0.6456
Entamoeba histolytica DNA topoisomerase II, putative 0.0294 0.337 0.9482
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.051 0.0978
Plasmodium falciparum DNA topoisomerase 2 0.0294 0.337 0.6457
Loa Loa (eye worm) doublecortin family protein 0.0021 0.012 0.0218
Mycobacterium tuberculosis Probable reductase 0.0162 0.18 0.3444
Plasmodium vivax amine transporter, putative 0.0016 0.0066 0.0127
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0252 0.0474
Trichomonas vaginalis 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0105 0.1121 0.2659
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0173
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.0252 0.0458
Echinococcus granulosus flap endonuclease 1 0.0027 0.0199 0.023
Schistosoma mansoni netrin receptor unc5 0.0015 0.0053 0.0063
Schistosoma mansoni nuclear receptor nhr-48 0.0015 0.0052 0.0062
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.051 0.097
Echinococcus granulosus Adrenodoxin mitochondrial 0.0012 0.0013 0.001
Schistosoma mansoni glutamate synthase 0.0053 0.0508 0.0598
Trypanosoma cruzi trypanothione reductase, putative 0.0201 0.2261 0.4329
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0128 0.1399 0.1395
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0336 0.094
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0435 0.0431
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0014 0.0035 0.0031
Brugia malayi kinase, mitochondrial precursor 0.0015 0.0056 0.0097
Trichomonas vaginalis sensor histidine kinase, putative 0.0015 0.0056 0.012
Echinococcus multilocularis acetylcholinesterase 0.0276 0.3145 0.3142
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0014 0.0035 0.0058
Plasmodium vivax JmjC domain containing protein 0.0016 0.007 0.0134
Echinococcus granulosus ryanodine receptor 44f 0.0014 0.0035 0.0037
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0051 0.0474 0.09
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.017 0.0478
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0121 0.0222
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0064
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0281 0.3211 0.5829
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0199 0.0361
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0039 0.0339 0.0335
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0182 0.0422
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0015 0.0052 0.0048
Trypanosoma cruzi Heat shock protein 83, putative 0.0015 0.0056 0.0098
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0406 0.0474
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0014 0.0035 0.0037
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0035 0.0037
Brugia malayi Thioredoxin reductase 0.045 0.5217 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.3524 0.8385
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0015 0.0051 0.0133
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0035 0.0042
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0006 0.0002
Loa Loa (eye worm) cytochrome P450 0.0015 0.0051 0.0092
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0435 0.0826
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0039 0.0339 0.0335
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0053 0.0508 0.0963
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0053 0.0508 0.1452
Loa Loa (eye worm) hypothetical protein 0.009 0.0941 0.1708
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Trichomonas vaginalis Ferredoxin 2 0.0012 0.0013 0.0018
Schistosoma mansoni adrenodoxin 0.0012 0.0013 0.0015
Leishmania major DNA topoisomerase III, putative 0.0016 0.0063 0.0111
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0162 0.18 0.5021
Onchocerca volvulus 0.0039 0.0339 0.1176
Toxoplasma gondii hypothetical protein 0.0108 0.1152 0.2209
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0162 0.18 0.3444
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0035 0.0031
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0016 0.0063 0.0069
Brugia malayi Muscleblind-like protein 0.0157 0.1739 0.3327
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0335 0.0331
Brugia malayi Endoplasmin precursor 0.0015 0.0056 0.0097
Echinococcus multilocularis conserved hypothetical protein 0.0014 0.0035 0.0031
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0162 0.18 0.3444
Onchocerca volvulus 0.0039 0.0339 0.1176
Schistosoma mansoni sodium/chloride dependent transporter 0.0016 0.0066 0.0078
Loa Loa (eye worm) hypothetical protein 0.0026 0.0182 0.0331
Leishmania major hypothetical protein, conserved 0.0026 0.0182 0.0341
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0109 0.0426
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0109 0.0199
Toxoplasma gondii transporter, cation channel family protein 0.0014 0.0035 0.0068
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0053 0.0508 0.1196
Loa Loa (eye worm) hypothetical protein 0.0017 0.0074 0.0134
Mycobacterium tuberculosis Probable oxidoreductase 0.031 0.3554 0.6808
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.017 0.0317
Echinococcus multilocularis thioredoxin glutathione reductase 0.045 0.5217 0.5215
Giardia lamblia 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0105 0.1121 0.3173
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0064
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0047 0.0427 0.0423
Mycobacterium ulcerans oxidoreductase 0.0012 0.0013 0.0024
Schistosoma mansoni transient receptor potential channel 0.0014 0.0035 0.0042
Echinococcus granulosus glutamate synthase 0.0053 0.0508 0.0593
Plasmodium vivax endoplasmin, putative 0.0015 0.0056 0.0107
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0233 0.027
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0335 0.1433
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0047 0.0427 0.0502
Brugia malayi ecdysteroid receptor 0.0032 0.0252 0.0474
Brugia malayi hypothetical protein 0.0015 0.0052 0.009
Brugia malayi Carboxylesterase family protein 0.0047 0.0427 0.0808
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0339 0.0394
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0053 0.0508 0.1452
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0015 0.0011
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0015 0.0051 0.0133
Loa Loa (eye worm) hypothetical protein 0.0475 0.5509 1
Schistosoma mansoni neuropeptide F-like receptor 0.0039 0.0339 0.0399
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0318 0.3645 0.6985
Loa Loa (eye worm) programmed cell death 8 0.0053 0.0508 0.0921
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0629 0.074
Entamoeba histolytica P-glycoprotein-2 0.0011 0.0006 0.0016
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0336 0.0332
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0016 0.0066 0.0078
Echinococcus granulosus orexin receptor type 2 0.0039 0.0339 0.0394
Plasmodium falciparum epoxide hydrolase 2 0.0026 0.0182 0.0341
Plasmodium falciparum exported lipase 1 0.0026 0.0182 0.0341
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0632 0.0628
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0039 0.0339 0.0335
Loa Loa (eye worm) norepinephrine transporter 0.0095 0.1006 0.1826
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0095 0.0172
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0252 0.0248
Trypanosoma cruzi metacaspase 5, putative 0.0047 0.0426 0.0809
Trypanosoma brucei DNA polymerase kappa, putative 0.0063 0.0628 0.1195
Loa Loa (eye worm) TYRA-2 protein 0.0039 0.0339 0.0615
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0123 0.1335 0.3843
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0339 0.0335
Brugia malayi hypothetical protein 0.0017 0.0074 0.0131
Trypanosoma cruzi heat shock protein 90, putative 0.0015 0.0056 0.0098
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0014 0.0035 0.0106
Echinococcus multilocularis shaker cognate 0.0014 0.0035 0.0031
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0039 0.0339 0.0399
Leishmania major hypothetical protein, unknown function 0.0014 0.0035 0.0059
Onchocerca volvulus 0.0016 0.0066 0.0214
Echinococcus multilocularis muscleblind protein 1 0.0157 0.1739 0.1736
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.0032 0.0062
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0071 0.0127
Onchocerca volvulus 0.0047 0.0427 0.1485
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0109 0.0198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0177 0.0408
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0211 0.0394
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0039 0.0339 0.0394
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0006 0.0002
Brugia malayi Melatonin receptor type 1A 0.0039 0.0339 0.064
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0362 0.0685
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0012 0.0013 0.0014
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0015 0.0056 0.0097
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0053 0.0508 0.0593
Schistosoma mansoni opsin-like receptor 0.0039 0.0339 0.0399
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0321 0.0606
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0036 0.0296 0.0292
Loa Loa (eye worm) acetyltransferase 0.0152 0.1684 0.3056
Echinococcus multilocularis fmrfamide receptor 0.0039 0.0339 0.0335
Plasmodium falciparum thioredoxin reductase 0.045 0.5217 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0015 0.0052 0.009
Echinococcus granulosus caspase 3 0.0076 0.0782 0.0917
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0435 0.0508
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0252 0.0297
Schistosoma mansoni glutamate synthase 0.0053 0.0508 0.0598
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.0252 0.0458
Brugia malayi Carboxylesterase family protein 0.0276 0.3145 0.6024
Brugia malayi nuclear hormone receptor family member odr-7 0.0015 0.0052 0.009
Trypanosoma brucei Metacaspase-4 0.0047 0.0426 0.0809
Brugia malayi hypothetical protein 0.0038 0.0323 0.0609
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.3524 0.8385
Loa Loa (eye worm) hypothetical protein 0.0047 0.0427 0.0774
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0015 0.0051 0.0133
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0015 0.0052 0.0095
Echinococcus granulosus sodium and chloride dependent glycine 0.0016 0.0066 0.0073
Schistosoma mansoni ryanodine receptor related 0.0014 0.0035 0.0042
Leishmania major monoglyceride lipase, putative 0.0303 0.3466 0.6641
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0037 0.0063
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0336 0.0635
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0011 0.0005 0.0009
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0083 0.0149
Echinococcus granulosus ferredoxin 0.0012 0.0013 0.001
Toxoplasma gondii transporter, cation channel family protein 0.0014 0.0035 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0024 0.0045
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.012
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0648 0.0763
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.0032 0.0062
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0064
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0323 0.032
Brugia malayi hypoxia-induced factor 1 0.0158 0.1754 0.3355
Brugia malayi AMP-binding enzyme family protein 0.0025 0.017 0.0315
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0053 0.0508 0.0593
Brugia malayi hypothetical protein 0.0021 0.012 0.022
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0128 0.1399 0.1643
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0074 0.0131
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0629 0.074
Loa Loa (eye worm) serotonin transporter b 0.0095 0.1006 0.1826
Plasmodium falciparum alpha/beta hydrolase fold domain containing protein, putative 0.0026 0.0182 0.0341
Leishmania major heat shock protein 83-1 0.0015 0.0056 0.0098
Trypanosoma brucei hypothetical protein, conserved 0.0053 0.0508 0.0965
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0051 0.0088
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0016 0.0066 0.0116
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0189 0.0362
Schistosoma mansoni biogenic amine (5HT) receptor 0.0039 0.0339 0.0399
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0016 0.0063 0.0113
Brugia malayi hypothetical protein 0.0039 0.0339 0.064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0062 0.0135
Loa Loa (eye worm) hypothetical protein 0.0017 0.0074 0.0134
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0108 0.1157 0.3328
Onchocerca volvulus 0.0016 0.0066 0.0214
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0254 0.0295
Schistosoma mansoni cpg binding protein 0.0032 0.0253 0.0298
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0035 0.0031
Echinococcus granulosus short transient receptor potential channel 6 0.0014 0.0037 0.0039
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0014 0.0035 0.0058
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0053 0.0508 0.0504
Loa Loa (eye worm) hypothetical protein 0.0047 0.0427 0.0774
Entamoeba histolytica P-glycoprotein-2, putative 0.0011 0.0006 0.0016
Toxoplasma gondii transporter, cation channel family protein 0.0076 0.0772 0.148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0291 0.0681
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0074 0.0087
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0095 0.0182
Echinococcus granulosus acetylcholinesterase 0.0276 0.3145 0.3701
Plasmodium vivax hypothetical protein, conserved 0.0047 0.0426 0.0817
Brugia malayi sulfakinin receptor protein 0.0039 0.0339 0.064
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0014 0.0035 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0182 0.0422
Onchocerca volvulus 0.0039 0.0339 0.1176
Brugia malayi larval opioid receptor 0.0039 0.0339 0.064
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0426 0.1003
Schistosoma mansoni gliotactin 0.0047 0.0427 0.0502
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0339 0.0394
Echinococcus multilocularis voltage dependent calcium channel 0.0128 0.1399 0.1395
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0053 0.0508 0.1196
Leishmania major mitochondrial DNA topoisomerase II 0.0331 0.3798 0.7278
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0053 0.0508 0.1196
Brugia malayi Dopamine receptor protein 1 0.0039 0.0339 0.064
Loa Loa (eye worm) CYP4Cod1 0.0024 0.016 0.029
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0071 0.0136
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0083 0.0149
Echinococcus granulosus g protein coupled receptor 0.0039 0.0339 0.0394
Schistosoma mansoni amine GPCR 0.0039 0.0339 0.0399
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.0252 0.0871
Toxoplasma gondii hypothetical protein 0.0026 0.0182 0.035
Plasmodium vivax lysophospholipase, putative 0.0026 0.0182 0.035
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0015 0.0056 0.0097
Loa Loa (eye worm) hypothetical protein 0.0043 0.0388 0.0705
Plasmodium falciparum metacaspase-like protein 0.0047 0.0426 0.0809
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0016 0.0066 0.0078
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0053 0.0508 0.1351
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Echinococcus multilocularis neuroligin 0.0047 0.0427 0.0423
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0039 0.0339 0.0615
Schistosoma mansoni nuclear receptor 0.0015 0.0052 0.0062
Leishmania major heat shock protein 83-1 0.0015 0.0056 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.0252 0.0474
Schistosoma mansoni DNA polymerase IV / kappa 0.0011 0.0005 0.0006
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0015 0.0056 0.0191
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.012 0.0137
Giardia lamblia Heat shock protein HSP 90-alpha 0.0015 0.0056 0.0146
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0053 0.0508 0.0963
Treponema pallidum hypothetical protein 0.0049 0.0453 0.1286
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0177 0.0408
Schistosoma mansoni caspase-7 (C14 family) 0.0123 0.1334 0.1571
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0016 0.0066 0.0127
Plasmodium vivax PST-A protein 0.0303 0.3466 0.6644
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0318 0.3645 0.6985
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.031 0.3554 0.6808
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0032 0.0062
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0336 0.0395
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0032 0.0052
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.017 0.0477
Onchocerca volvulus 0.0047 0.0427 0.1485
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.017 0.0477
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.0252 0.0248
Mycobacterium ulcerans two component regulator - sensor kinase 0.0015 0.0056 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0291 0.0681
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.017 0.0477
Trypanosoma cruzi hypothetical protein, conserved 0.0053 0.0508 0.0965
Mycobacterium leprae conserved hypothetical protein 0.0021 0.0126 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0426 0.1003
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0128 0.1399 0.1647
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0109 0.0105
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0303 0.3466 0.8248
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0201 0.2261 0.2663
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0254 0.03
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0172 0.1914 0.5516
Brugia malayi Death domain containing protein 0.0015 0.0053 0.0092
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.031 0.3555 1
Brugia malayi hypothetical protein 0.0039 0.0339 0.064
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0182 0.035
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0026 0.0182 0.0341
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0109 0.0199
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0019 0.0096 0.0092
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0404 0.0766
Mycobacterium ulcerans DNA gyrase subunit B 0.0172 0.1913 0.5512
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0062 0.0113
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0047 0.0427 0.1003
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0321 0.0606
Plasmodium vivax lysophospholipase, putative 0.0026 0.0182 0.035
Toxoplasma gondii hypothetical protein 0.0062 0.061 0.117
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.015 0.1659 0.3173
Plasmodium vivax DNA gyrase subunit B, putative 0.0172 0.1913 0.3666
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0426 0.1003
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0121 0.0276
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0201 0.2261 0.4329
Echinococcus granulosus g-protein coupled receptor 0.0039 0.0339 0.0394
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.025 0.0583
Brugia malayi hypothetical protein 0.0027 0.0189 0.0351
Trypanosoma cruzi DNA topoisomerase III, putative 0.0016 0.0063 0.0111
Mycobacterium leprae Conserved hypothetical protein 0.0015 0.0051 0.0054
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0189 0.0353
Schistosoma mansoni biogenic amine receptor 0.0039 0.0339 0.0399
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0109 0.03
Mycobacterium tuberculosis Carboxylesterase LipT 0.0047 0.0427 0.0808
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0307 0.3524 0.9913
Echinococcus multilocularis muscleblind protein 0.0157 0.1739 0.1736
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.001
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0015 0.0056 0.0191
Trypanosoma cruzi hydrolase, alpha/beta fold family, putative 0.0026 0.0182 0.0341
Loa Loa (eye worm) hypothetical protein 0.0076 0.0772 0.1401
Plasmodium vivax SET domain protein, putative 0.0032 0.0254 0.0488
Brugia malayi neuropeptide F receptor 0.0039 0.0339 0.064
Loa Loa (eye worm) RecQ helicase 0.0021 0.0121 0.022
Giardia lamblia DNA topoisomerase III 0.0016 0.0063 0.0164
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0201 0.2261 0.4329
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0199 0.0382
Echinococcus granulosus FTZ F1 alpha 0.0032 0.0252 0.0293
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0304 0.0712
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0629 0.0736
Echinococcus granulosus tm gpcr rhodopsin 0.0039 0.0339 0.0394
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0039 0.0339 0.0335
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.3524 0.8385
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0064
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0021 0.0121 0.0224
Trypanosoma brucei monoglyceride lipase, putative 0.0303 0.3466 0.6641
Schistosoma mansoni sulfide quinone reductase 0.0053 0.0508 0.0598
Loa Loa (eye worm) hypothetical protein 0.0276 0.3145 0.5708
Echinococcus multilocularis lamin 0.0028 0.0211 0.0207
Mycobacterium ulcerans hypothetical protein 0.0026 0.0182 0.0513
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0037 0.0063
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0015 0.0056 0.0052
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0294 0.337 0.3966
Schistosoma mansoni hypothetical protein 0.0132 0.1446 0.1703
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0014 0.0035 0.0059
Onchocerca volvulus 0.0039 0.0339 0.1176
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0032 0.0033
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0015 0.0056 0.0069
Brugia malayi Protein kinase domain containing protein 0.0016 0.0059 0.0103
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0039 0.0339 0.0399
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0053 0.0097
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0012 0.0013 0.0016
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0037 0.0063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0339 0.0399
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0252 0.0474
Echinococcus multilocularis neuropeptide receptor 0.0039 0.0339 0.0335
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0015 0.0051 0.0087
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0053 0.0508 0.0965
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.016 0.029
Echinococcus multilocularis glutamate synthase 0.0053 0.0508 0.0504
Onchocerca volvulus 0.0039 0.0339 0.1176
Loa Loa (eye worm) hypothetical protein 0.0021 0.012 0.0218
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0016 0.0063 0.0111
Trichomonas vaginalis aldehyde oxidase, putative 0.0364 0.4201 1
Giardia lamblia Cgi67 serine protease precursor-like protein 0.0026 0.0182 0.0505
Leishmania major hypothetical protein, conserved 0.0053 0.0508 0.0965
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0062 0.011
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0016 0.0063 0.022
Brugia malayi Doublecortin family protein 0.0021 0.012 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0177 0.0408
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.015 0.1659 0.3173
Schistosoma mansoni caspase-3 (C14 family) 0.0123 0.1334 0.1571
Schistosoma mansoni ap endonuclease 0.002 0.0109 0.0128
Leishmania major 2,3-bisphosphoglycerate-independent phosphoglycerate mutase-like 0.0017 0.0078 0.014
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0096 0.0175
Trypanosoma cruzi adrenodoxin precursor, putative 0.0012 0.0013 0.0016
Leishmania major heat shock protein 83-1 0.0015 0.0056 0.0098
Echinococcus multilocularis phd:f box containing protein 0.0016 0.007 0.0066
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.3524 0.8385
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0064 0.0638 0.1214
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0339 0.0335
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0053 0.0169
Schistosoma mansoni hypothetical protein 0.0039 0.0339 0.0399
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.0252 0.0293
Toxoplasma gondii thioredoxin reductase 0.045 0.5217 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0152 0.1684 0.1983
Plasmodium vivax alpha/beta hydrolase, putative 0.0026 0.0182 0.035
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.051 0.097
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0014 0.0035 0.0058
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0039 0.0339 0.0335
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0014 0.0035 0.0042
Entamoeba histolytica recQ family helicase, putative 0.0021 0.0121 0.0341
Loa Loa (eye worm) hypothetical protein 0.0015 0.0052 0.0095
Brugia malayi isocitrate dehydrogenase 0.0017 0.0071 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0209 0.0485
Brugia malayi Carboxylesterase family protein 0.0276 0.3145 0.6024
Toxoplasma gondii phospholipase 0.0026 0.0182 0.035
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0053 0.0508 0.0963
Trypanosoma cruzi DNA topoisomerase II, putative 0.0279 0.3182 0.6095
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0015 0.0051 0.0133
Echinococcus multilocularis neuropeptide receptor 0.0039 0.0339 0.0335
Echinococcus multilocularis two pore calcium channel protein 2 0.0014 0.0035 0.0031
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0016 0.0063 0.0111
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.051 0.097
Trichomonas vaginalis Ferredoxin 3 0.0012 0.0013 0.0018
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0096 0.0109
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0035 0.0037
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0062 0.011
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0015 0.0051 0.0087
Schistosoma mansoni BC026374 protein (S09 family) 0.0047 0.0427 0.0502
Echinococcus multilocularis heat shock protein 0.0015 0.0056 0.0052
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Brugia malayi hypothetical protein 0.0043 0.0388 0.0735
Echinococcus multilocularis Ankyrin 0.0015 0.0055 0.0051
Brugia malayi DNA topoisomerase III 0.0016 0.0063 0.0109
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0039 0.0339 0.1176
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0055 0.0065
Schistosoma mansoni hypothetical protein 0.0039 0.0339 0.0399
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0336 0.0391
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0128 0.1399 0.1643
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0201 0.2261 0.4329
Loa Loa (eye worm) hypothetical protein 0.0019 0.0096 0.0175
Leishmania major trypanothione reductase 0.045 0.5217 1
Treponema pallidum sodium- and chloride- dependent transporter 0.0095 0.1006 0.2855
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0015 0.0056 0.0098
Mycobacterium ulcerans electron transfer protein 0.0012 0.0013 0.0024
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0015 0.0051 0.0087
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.0252 0.0297
Trypanosoma cruzi DNA polymerase kappa, putative 0.0063 0.0628 0.1195
Trypanosoma brucei DNA polymerase kappa, putative 0.0063 0.0628 0.1195
Echinococcus multilocularis geminin 0.0178 0.199 0.1987
Loa Loa (eye worm) hypothetical protein 0.0039 0.0336 0.0609
Mycobacterium ulcerans two component sensor kinase MprB 0.0015 0.0056 0.0148
Leishmania major heat shock protein 83-1 0.0015 0.0056 0.0098
Toxoplasma gondii hypothetical protein 0.0051 0.0482 0.0924
Trypanosoma cruzi heat shock protein 90, putative 0.0015 0.0056 0.0098
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0252 0.0293
Brugia malayi putative neuropeptide receptor 0.0039 0.0339 0.064
Mycobacterium ulcerans hydrolase 0.0026 0.0182 0.0513
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0011 0.0005 0.0009
Echinococcus multilocularis BC026374 protein (S09 family) 0.0047 0.0427 0.0423
Trypanosoma brucei DNA topoisomerase ii 0.0331 0.3798 0.7278
Plasmodium falciparum exported lipase 2 0.0026 0.0182 0.0341
Onchocerca volvulus Cell death protein 3 homolog 0.009 0.0941 0.3298
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0015 0.0051 0.0087
Loa Loa (eye worm) voltage-gated potassium channel 0.0014 0.0035 0.0064
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0199 0.0552
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0121 0.0222
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.017 0.0477
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.0252 0.0474
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.0793 0.093
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0015 0.0051 0.0133
Trypanosoma cruzi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0017 0.0078 0.014
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.007 0.0066
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.016 0.0298
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0303 0.3466 0.9752
Onchocerca volvulus 0.0039 0.0339 0.1176
Echinococcus multilocularis acetylcholinesterase 0.0276 0.3145 0.3142
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0182 0.0422
Leishmania major heat shock protein 83-1 0.0015 0.0056 0.0098
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0039 0.0339 0.0399
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0026 0.0182 0.0422
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0015 0.0056 0.0098
Loa Loa (eye worm) hypothetical protein 0.0172 0.1912 0.347
Mycobacterium ulcerans DNA topoisomerase I 0.0016 0.0063 0.0167
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0254 0.03
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0019 0.0096 0.0092
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0109 0.0199
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0014 0.0035 0.0037
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.0252 0.0297
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0015 0.0056 0.012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0062 0.0135
Loa Loa (eye worm) hypothetical protein 0.0036 0.0296 0.0537
Echinococcus multilocularis transient receptor potential cation channel 0.0014 0.0037 0.0033
Echinococcus multilocularis transfer RNA-Gly 0.0014 0.0035 0.0031
Echinococcus multilocularis potassium large conductance calcium activated 0.0014 0.0035 0.0031
Plasmodium falciparum lysophospholipase, putative 0.031 0.3555 0.681
Leishmania major heat shock protein 83-1 0.0015 0.0056 0.0098
Loa Loa (eye worm) G-protein coupled receptor 0.0039 0.0339 0.0615
Trypanosoma cruzi NADH dehydrogenase, putative 0.0053 0.0508 0.0965
Trypanosoma brucei metacaspase MCA2 0.0047 0.0426 0.0809
Echinococcus granulosus neuropeptide receptor 0.0039 0.0339 0.0394
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0032 0.0058
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0015 0.0051 0.0087
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0096 0.0113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0291 0.0681
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0201 0.2261 0.6518
Trypanosoma cruzi DNA topoisomerase III, putative 0.0016 0.0063 0.0111
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0109 0.0246
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0016 0.0063 0.0087
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0339 0.0399
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.012 0.0116
Echinococcus granulosus short transient receptor potential channel 6 0.0014 0.0035 0.0037
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0199 0.0373
Entamoeba histolytica ;Alias 0.0026 0.0182 0.0513
Plasmodium falciparum amino acid transporter, putative 0.0016 0.0066 0.0118
Schistosoma mansoni biogenic amine receptor 0.0039 0.0339 0.0399
Brugia malayi jmjC domain containing protein 0.0062 0.0608 0.1157
Onchocerca volvulus 0.0039 0.0339 0.1176
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.051 0.0601
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.0252 0.0458
Echinococcus multilocularis voltage gated potassium channel 0.0014 0.0035 0.0031
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.0339 0.0335
Plasmodium falciparum esterase, putative 0.031 0.3555 0.681
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0201 0.2261 0.4329
Trichomonas vaginalis apoptosis inducing factor, putative 0.0053 0.0508 0.1196
Plasmodium falciparum lysophospholipase, putative 0.0303 0.3466 0.6641
Trypanosoma brucei metacaspase MCA3 0.0047 0.0426 0.0809
Echinococcus granulosus para nitrobenzyl esterase 0.0047 0.0427 0.0498
Trypanosoma cruzi DNA topoisomerase II, putative 0.0279 0.3182 0.6095
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0062 0.0108
Echinococcus multilocularis dna polymerase eta 0.0036 0.0296 0.0292
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0016 0.0063 0.0074
Schistosoma mansoni nuclear receptor 0.0015 0.0052 0.0062
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0211 0.0382
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0015 0.0056 0.0052
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0015 0.0051 0.0133
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0056 0.0107
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0632 0.1204
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0016 0.0063 0.012
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0022 0.0139 0.0255
Schistosoma mansoni multidrug resistance protein 0.0011 0.0006 0.0007
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0109 0.0197
Schistosoma mansoni family S9 unassigned peptidase (S09 family) 0.0026 0.0182 0.0215
Schistosoma mansoni hypothetical protein 0.0015 0.0051 0.006
Leishmania major protein kinase, putative 0.0019 0.0098 0.018
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0071 0.0084
Plasmodium falciparum alpha/beta hydrolase, putative 0.0026 0.0182 0.0341
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0011 0.0006 0.0011
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0081 0.0831 0.2269
Schistosoma mansoni biogenic amine receptor 0.0039 0.0339 0.0399
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0016 0.0063 0.0069
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0015 0.0056 0.012
Loa Loa (eye worm) hypothetical protein 0.0015 0.0056 0.0102
Mycobacterium ulcerans endonuclease IV 0.0081 0.0831 0.2387
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0128 0.1399 0.1395
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0007
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0015 0.0056 0.0097
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0021 0.0121 0.0224
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.0252 0.0248
Plasmodium vivax PST-A protein 0.0026 0.0182 0.035
Leishmania major ferredoxin, 2fe-2s-like protein 0.0012 0.0013 0.0016
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0095 0.1006 0.192
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0053 0.0508 0.0593
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0201 0.2261 0.4334
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0064
Echinococcus multilocularis ryanodine receptor 44f 0.0014 0.0035 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0336 0.0787
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0064
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0335 0.0954
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0014 0.0035 0.0058
Plasmodium vivax unspecified product 0.0026 0.0182 0.035
Echinococcus multilocularis folate receptor beta 0.0108 0.1152 0.1149
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0015 0.0051 0.0087
Echinococcus granulosus death domain containing protein 0.0015 0.0053 0.0058
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0039 0.0339 0.0335
Echinococcus granulosus transient receptor potential gamma protein 0.0014 0.0035 0.0037
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0015 0.0056 0.0148
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0039 0.0339 0.0335
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0053 0.0508 0.0963
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0339 0.0399
Loa Loa (eye worm) independent phosphoglycerate mutase isoform 2 0.0105 0.1121 0.2035
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0201 0.2261 0.4329
Loa Loa (eye worm) hypothetical protein 0.0019 0.0095 0.0173
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0022 0.0139 0.0159
Leishmania major heat shock protein 83-1 0.0015 0.0056 0.0098
Trichomonas vaginalis receptor histidine kinase, putative 0.0015 0.0056 0.012
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.015 0.1657 0.4614
Onchocerca volvulus 0.0047 0.0427 0.1485
Trypanosoma cruzi metacaspase, putative 0.0047 0.0426 0.0809
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0053 0.0508 0.0504
Mycobacterium ulcerans glutamate synthase subunit beta 0.0053 0.0508 0.1452
Trypanosoma brucei DNA polymerase kappa, putative 0.0063 0.0628 0.1195
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0029 0.0214 0.0924
Echinococcus multilocularis abhydrolase domain containing 3 0.0026 0.0182 0.0178
Loa Loa (eye worm) hypothetical protein 0.0032 0.0252 0.0458
Schistosoma mansoni voltage-dependent calcium channel 0.0014 0.0035 0.0042
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.007 0.0066
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.012 0.0116
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0121 0.0276
Giardia lamblia GTOR 0.0047 0.0435 0.1223
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0012 0.0013 0.0025
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0039 0.0339 0.0399
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0189 0.0353
Echinococcus multilocularis neuropeptide s receptor 0.0523 0.6084 0.6082
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0051 0.0474 0.0553
Loa Loa (eye worm) carboxylesterase 0.0276 0.3145 0.5708
Loa Loa (eye worm) hypothetical protein 0.0015 0.0052 0.0095
Echinococcus granulosus dro:myosuppressin receptor 0.0039 0.0339 0.0394
Onchocerca volvulus 0.0039 0.0339 0.1176
Echinococcus multilocularis monoacylglycerol lipase abhd12 0.0026 0.0182 0.0178
Brugia malayi G protein-coupled receptor F59B2.13 0.0039 0.0339 0.064
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0064
Loa Loa (eye worm) hypothetical protein 0.0062 0.061 0.1108
Onchocerca volvulus 0.0038 0.0323 0.1121
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0071 0.0127
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0435 0.1224
Toxoplasma gondii cytochrome p450 superfamily protein 0.0015 0.0051 0.0097
Onchocerca volvulus 0.0028 0.0211 0.0723
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0289 0.0524
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0022 0.0139 0.0135
Echinococcus granulosus dna polymerase kappa 0.0063 0.0628 0.0735
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0638 0.1831
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0053 0.0508 0.1428
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.0252 0.0458
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0321 0.0606
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0199 0.2237 0.7868
Trypanosoma cruzi heat shock protein 85, putative 0.0015 0.0056 0.0098
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0039 0.0339 0.0335
Onchocerca volvulus 0.0014 0.0035 0.0106
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0014 0.0035 0.0058
Plasmodium vivax ferrodoxin reductase, putative 0.0053 0.0508 0.0973
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0109 0.0246
Mycobacterium ulcerans NADH dehydrogenase 0.0053 0.0508 0.1452
Echinococcus multilocularis fmrfamide receptor 0.0039 0.0339 0.0335
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.012 0.0221
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.017 0.0478
Leishmania major DNA topoisomerase 1A 0.0016 0.0063 0.0111
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0053 0.0508 0.1428
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0053 0.0508 0.0973
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0139 0.0163
Loa Loa (eye worm) ion channel NompC 0.0014 0.0035 0.0064
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0026 0.0182 0.0422
Echinococcus granulosus thioredoxin glutathione reductase 0.045 0.5217 0.6142
Schistosoma mansoni lamin 0.0028 0.0211 0.0248
Plasmodium falciparum ferredoxin, putative 0.0012 0.0013 0.0016
Brugia malayi nuclear hormone receptor family member nhr-6 0.0015 0.0052 0.009
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0201 0.2261 1
Echinococcus multilocularis g protein coupled receptor 0.0039 0.0339 0.0335
Loa Loa (eye worm) hypothetical protein 0.0032 0.0252 0.0458
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.0426 0.0817
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0426 0.1003
Toxoplasma gondii protein c14orf29, putative 0.0026 0.0182 0.035
Loa Loa (eye worm) hypothetical protein 0.0199 0.224 0.4066
Loa Loa (eye worm) solute carrier family 6 member 4 0.0095 0.1006 0.1826
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.005 0.0466 0.0883
Loa Loa (eye worm) hypothetical protein 0.0016 0.007 0.0127
Echinococcus multilocularis transient receptor potential gamma protein 0.0014 0.0035 0.0031
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0015 0.0056 0.012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0201 0.2261 0.4329
Leishmania major NADH dehydrogenase, putative 0.0053 0.0508 0.0965
Loa Loa (eye worm) hypothetical protein 0.0047 0.0426 0.0774
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0015 0.0056 0.0148
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.007 0.0077
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0252 0.0474
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0015 0.0051 0.0133
Trichomonas vaginalis Clan SC, family S9, unassigned serine peptidase 0.0026 0.0182 0.0422
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0014 0.0035 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.0252 0.0474
Echinococcus multilocularis lamin dm0 0.0028 0.0211 0.0207
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.0252 0.0458
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0201 0.2261 0.4329
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0064 0.0638 0.0752
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0054 0.0098
Schistosoma mansoni amine GPCR 0.0039 0.0339 0.0399
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0014 0.0035 0.0031
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0071 0.0127
Giardia lamblia Pms1-like protein 0.0015 0.0056 0.0146
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.007 0.0127
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0053 0.0508 0.1429
Schistosoma mansoni endoplasmin 0.0015 0.0056 0.0066
Brugia malayi Probable DNA topoisomerase II 0.0294 0.337 0.6456
Echinococcus granulosus neuroligin 0.0047 0.0427 0.0498
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0109 0.0208
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0053 0.0508 0.1351
Brugia malayi Serotonin receptor 0.0039 0.0339 0.064
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.012 0.023
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0336 0.0787
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0016 0.0066 0.0073
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0426 0.1003
Echinococcus granulosus shaker cognate 0.0014 0.0035 0.0037
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0336 0.0391
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0336 0.0635
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0491 0.0579
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0015 0.0051 0.0087
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0071 0.0067
Trypanosoma cruzi DNA topoisomerase III, putative 0.0016 0.0063 0.0111
Echinococcus granulosus lamin 0.0028 0.0211 0.0243
Mycobacterium ulcerans oxidoreductase 0.0012 0.0013 0.0024
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0047 0.0426 0.0807
Leishmania major p-glycoprotein 0.0011 0.0006 0.0001
Schistosoma mansoni inositol monophosphatase 0.0039 0.0335 0.0395
Trypanosoma cruzi Alpha/beta hydrolase family, putative 0.0026 0.0182 0.0341
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0015 0.0056 0.0097
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0015 0.0051 0.0133
Loa Loa (eye worm) hypothetical protein 0.0032 0.0252 0.0458
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0053 0.0092
Treponema pallidum quinoline 2-oxidoreductase 0.0058 0.0561 0.1592
Plasmodium falciparum DNA gyrase subunit B 0.0172 0.1913 0.366
Leishmania major heat shock protein 83-1 0.0015 0.0056 0.0098
Echinococcus granulosus neuropeptide receptor 0.0039 0.0339 0.0394
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.0126 0.0423
Loa Loa (eye worm) hypothetical protein 0.0022 0.0139 0.0252
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0039 0.0339 0.0399
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0015 0.0051 0.0088
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0021 0.0121 0.022
Echinococcus granulosus caspase 8 0.0047 0.0426 0.0497
Schistosoma mansoni pyruvate dehydrogenase 0.0015 0.0056 0.0066
Brugia malayi hypothetical protein 0.0128 0.1394 0.2664
Toxoplasma gondii phospholipase/carboxylesterase 0.0026 0.0182 0.035
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0638 0.0747
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0172 0.1913 0.3659
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0016 0.0066 0.0073
Echinococcus granulosus neuropeptides capa receptor 0.0039 0.0339 0.0394
Loa Loa (eye worm) neuropeptide F receptor 0.0039 0.0339 0.0615
Trypanosoma brucei 2,3-bisphosphoglycerate-independent phosphoglycerate mutase-like protein, putative 0.0017 0.0078 0.014
Loa Loa (eye worm) hypothetical protein 0.0095 0.1006 0.1826
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0035 0.0042
Schistosoma mansoni DNA helicase recq5 0.0021 0.0121 0.0143
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0015 0.0052 0.0048
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0026 0.0182 0.0422
Schistosoma mansoni neuropeptide receptor 0.0039 0.0339 0.0399
Brugia malayi hypothetical protein 0.0017 0.0074 0.0131
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0406 0.0955
Loa Loa (eye worm) STAT protein 0.0138 0.1516 0.2752
Trichomonas vaginalis heat shock protein, putative 0.0015 0.0056 0.012
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.051 0.1436
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.015 0.1657 0.3168
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0015 0.0051 0.0087
Plasmodium vivax lysophospholipase, putative 0.031 0.3555 0.6813
Brugia malayi hypothetical protein 0.0172 0.1912 0.3658
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0053 0.0508 0.0973
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0052 0.0166
Loa Loa (eye worm) hypothetical protein 0.0015 0.0055 0.01
Onchocerca volvulus 0.0039 0.0339 0.1176
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0062 0.0135
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.051 0.1203
Loa Loa (eye worm) hypothetical protein 0.0015 0.0052 0.0095
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0406 0.0778
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0182 0.035
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Echinococcus granulosus serotonin transporter 0.0095 0.1006 0.1181
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0039 0.0339 0.0335
Onchocerca volvulus 0.0013 0.0032 0.0092
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0036 0.0296 0.0343
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0053 0.0049
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0016 0.0066 0.0078
Leishmania major heat shock protein 83-1 0.0015 0.0056 0.0098
Schistosoma mansoni lipoxygenase 0.0087 0.0903 0.1064
Loa Loa (eye worm) hypothetical protein 0.0025 0.017 0.0308
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.015 0.1657 0.4772
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0012 0.0013 0.0016
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0015 0.0051 0.0087
Schistosoma mansoni smdr2 0.0011 0.0006 0.0007
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0042 0.0378 0.0715
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0052 0.0048
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0021 0.0121 0.0117
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0152 0.1684 0.168
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0053 0.0508 0.22
Schistosoma mansoni disulfide oxidoreductase 0.0053 0.0508 0.0598
Schistosoma mansoni cpg binding protein 0.0032 0.0253 0.0298
Schistosoma mansoni neuropeptide receptor 0.0039 0.0339 0.0399
Entamoeba histolytica hypothetical protein 0.0038 0.0323 0.0909
Echinococcus granulosus fmrfamide receptor 0.0039 0.0339 0.0394
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0336 0.0787
Loa Loa (eye worm) hypothetical protein 0.0015 0.0052 0.0095
Echinococcus multilocularis neuropeptide FF receptor 2 0.0039 0.0339 0.0335
Trypanosoma brucei heat shock protein, putative 0.0015 0.0056 0.0098
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.012 0.0137
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0052 0.0057
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0201 0.2261 0.2258
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0081 0.0831 0.1584
Schistosoma mansoni thyroid hormone receptor 0.0164 0.1825 0.2149
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0053 0.0063
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.017 0.0478
Loa Loa (eye worm) neuropeptide F receptor 0.0039 0.0339 0.0615
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0339 0.0399
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0172 0.1913 0.845
Echinococcus multilocularis multidrug resistance protein 1 0.0011 0.0006 0.0001
Echinococcus granulosus histone acetyltransferase KAT2B 0.0148 0.1633 0.1919
Giardia lamblia Sgs1 DNA helicase, putative 0.0021 0.0121 0.0331
Loa Loa (eye worm) hypothetical protein 0.0026 0.0182 0.0331
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0121 0.0224
Mycobacterium ulcerans DNA polymerase IV 0.0063 0.0628 0.1799
Plasmodium vivax heat shock protein 86, putative 0.0015 0.0056 0.0107
Loa Loa (eye worm) hypothetical protein 0.012 0.1296 0.2352
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0006 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0063 0.0628 0.1195
Echinococcus multilocularis allatostatin A receptor 0.0039 0.0339 0.0335
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0014 0.0035 0.0058
Brugia malayi Carboxylesterase family protein 0.0047 0.0427 0.0808
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0015 0.0051 0.0087
Brugia malayi jmjC domain containing protein 0.0064 0.0629 0.1196
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0063 0.0628 0.1195
Plasmodium vivax unspecified product 0.031 0.3555 0.6813
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.0339 0.0399
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Trypanosoma brucei 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0105 0.1121 0.2142
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0062 0.011
Schistosoma mansoni hypothetical protein 0.0014 0.0035 0.0042
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0064 0.0638 0.1214
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0201 0.2261 0.4329
Echinococcus granulosus 7tm_1 domain containing protein 0.0039 0.0339 0.0394
Plasmodium falciparum alpha/beta-hydrolase, putative 0.0026 0.0182 0.0341
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.007 0.0134
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0426 0.1003
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0124 0.1347 0.1343
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0053 0.0508 0.0963
Leishmania major cytochrome p450-like protein 0.0015 0.0051 0.0088
Plasmodium falciparum metacaspase 1 0.0047 0.0426 0.0809
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0014 0.0035 0.0031
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0024 0.016 0.0449
Echinococcus multilocularis neuropeptides capa receptor 0.0039 0.0339 0.0335
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.017 0.0317
Trypanosoma brucei DNA polymerase eta, putative 0.0036 0.0296 0.0558
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0032 0.0033
Echinococcus multilocularis tumor protein p63 0.0355 0.4093 0.4091
Schistosoma mansoni DNA helicase recq1 0.0021 0.0121 0.0143
Loa Loa (eye worm) hypothetical protein 0.0053 0.0508 0.0921
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0016 0.0066 0.0062
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0071 0.0067
Brugia malayi Serotonin receptor 0.0039 0.0339 0.064
Echinococcus granulosus potassium voltage gated channel subfamily H 0.005 0.0466 0.0544
Plasmodium falciparum DNA topoisomerase 3, putative 0.0016 0.0063 0.0111
Loa Loa (eye worm) multidrug resistance protein 3 0.0011 0.0006 0.001
Schistosoma mansoni endoplasmin 0.0015 0.0056 0.0066
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.007 0.0082
Toxoplasma gondii hydrolase, alpha/beta fold family protein 0.0026 0.0182 0.035
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0015 0.0051 0.0087
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0032 0.0062
Loa Loa (eye worm) hypothetical protein 0.0026 0.0182 0.0331
Chlamydia trachomatis DNA gyrase subunit B 0.0172 0.1913 0.8455
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0015 0.0052 0.0057
Onchocerca volvulus 0.0028 0.0211 0.0723
Onchocerca volvulus 0.0039 0.0339 0.1176
Toxoplasma gondii ferredoxin, putative 0.0012 0.0013 0.0025
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0062 0.0608 0.0604
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0053 0.0058
Trypanosoma brucei DNA polymerase kappa, putative 0.0063 0.0628 0.1195
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0015 0.0051 0.0088
Schistosoma mansoni hypothetical protein 0.043 0.4982 0.5867
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0047 0.0426 0.0817
Brugia malayi Pre-SET motif family protein 0.0032 0.0254 0.0478
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0012 0.0013 0.0016
Toxoplasma gondii NADPH-glutathione reductase 0.0201 0.2261 0.4334
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0124 0.1347 0.1582
Echinococcus multilocularis dna polymerase kappa 0.0063 0.0628 0.0624
Leishmania major heat shock protein 83-1 0.0015 0.0056 0.0098
Loa Loa (eye worm) hypothetical protein 0.0013 0.003 0.0055
Giardia lamblia DINP protein human, muc B family 0.0042 0.0378 0.1061
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.0252 0.0474
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0071 0.0067
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0542 0.0984
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0435 0.1224
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0291 0.0681
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Onchocerca volvulus 0.0025 0.017 0.058
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0053 0.0508 0.1196
Plasmodium falciparum heat shock protein 90 0.0015 0.0056 0.0098
Schistosoma mansoni biogenic amine (5HT) receptor 0.0039 0.0339 0.0399
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.0252 0.0297
Toxoplasma gondii hypothetical protein 0.031 0.3555 0.6813
Trichomonas vaginalis conserved hypothetical protein 0.031 0.3555 0.8458
Schistosoma mansoni hypothetical protein 0.0015 0.0053 0.0063
Loa Loa (eye worm) hypothetical protein 0.0015 0.0052 0.0095
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0123 0.1334 0.1331
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0629 0.1141
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0035 0.0042
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0036 0.0038
Echinococcus granulosus intermediate filament protein 0.0028 0.0211 0.0243
Echinococcus granulosus transient receptor potential cation channel 0.0014 0.0037 0.0039
Plasmodium falciparum alpha/beta hydrolase, putative 0.0026 0.0182 0.0341
Onchocerca volvulus 0.0053 0.0508 0.177
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0039 0.0339 0.064
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0404 0.0766
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.032 0.075
Echinococcus multilocularis orexin receptor type 2 0.0039 0.0339 0.0335
Echinococcus multilocularis sodium and chloride dependent glycine 0.0016 0.0066 0.0062
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.005 0.0466 0.0845
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.0252 0.0248
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.016 0.0298
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.0252 0.0248
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.0252 0.0458
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Trichomonas vaginalis Ferredoxin 7 0.0012 0.0013 0.0018
Loa Loa (eye worm) hypothetical protein 0.0025 0.017 0.0308
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0128 0.1399 0.1647
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0335 0.0785
Echinococcus multilocularis dnaJ subfamily B 0.043 0.4982 0.498
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0632 0.074
Schistosoma mansoni transient receptor potential channel 4 0.0014 0.0035 0.0042
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0081 0.0831 0.1584
Trypanosoma cruzi adrenodoxin precursor, putative 0.0012 0.0013 0.0016
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0035 0.0042
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0015 0.0056 0.0097
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.007 0.07 0.2009
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0303 0.3466 0.9752
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.007 0.0125
Echinococcus granulosus bloom syndrome protein 0.0021 0.0121 0.0138
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0053 0.0508 0.0593
Loa Loa (eye worm) voltage-gated potassium channel 0.0014 0.0035 0.0064
Mycobacterium ulcerans putative regultory protein 0.0015 0.0056 0.0148
Loa Loa (eye worm) hypothetical protein 0.0052 0.0491 0.0892
Echinococcus multilocularis short transient receptor potential channel 6 0.0014 0.0037 0.0033
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0279 0.3182 0.6095
Toxoplasma gondii hypothetical protein 0.0014 0.0035 0.0068
Brugia malayi Dopamine receptor 0.0039 0.0339 0.064
Leishmania major 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0105 0.1121 0.2142
Entamoeba histolytica P-glycoprotein 5, putative 0.0011 0.0006 0.0016
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0016 0.0066 0.0127
Onchocerca volvulus 0.0039 0.0339 0.1176
Echinococcus multilocularis g-protein coupled receptor 0.0039 0.0339 0.0335
Entamoeba histolytica DNA topoisomerase III, putative 0.0016 0.0063 0.0176
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0042 0.0378 0.0716
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.0252 0.0293
Brugia malayi AKH receptor 0.0039 0.0339 0.064
Echinococcus granulosus caspase 0.0123 0.1334 0.1567
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0276 0.3145 0.3704
Leishmania major hypothetical protein, conserved 0.0053 0.0508 0.0965
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.0252 0.0297
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.017 0.0315
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.0252 0.0871
Schistosoma mansoni vesicular amine transporter 0.0014 0.0035 0.0042
Echinococcus multilocularis caspase 3 0.0076 0.0782 0.0778
Leishmania major metacaspase, putative 0.0047 0.0426 0.0809
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0071 0.0079
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0015 0.0051 0.0087
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0053 0.0508 0.0504
Echinococcus granulosus hypothetical protein 0.0014 0.0035 0.0037
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.051 0.0596
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0336 0.0332
Toxoplasma gondii heat shock protein HSP90 0.0015 0.0056 0.0107
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0018 0.009 0.0086
Trichomonas vaginalis 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0017 0.0078 0.0172
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0039 0.0339 0.0399
Giardia lamblia DNA topoisomerase II 0.0279 0.3188 0.9047
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0096 0.0109
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0109 0.0309
Schistosoma mansoni jumonji domain containing protein 0.0016 0.007 0.0082
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0016 0.0063 0.0058
Leishmania major hypothetical protein, conserved 0.0012 0.0013 0.0016
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.051 0.1203
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0036 0.0296 0.0537
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0047 0.0426 0.1003
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0016 0.0066 0.0062
Echinococcus multilocularis g protein coupled receptor 0.0039 0.0339 0.0335
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0015 0.0056 0.0097
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0039 0.0339 0.0335
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0039 0.0339 0.0394
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0096 0.0113
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Brugia malayi hypothetical protein 0.0039 0.0339 0.064
Plasmodium falciparum alpha/beta hydrolase, putative 0.0026 0.0182 0.0341
Loa Loa (eye worm) hypothetical protein 0.0027 0.0189 0.0342
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0148 0.1627 0.3112
Schistosoma mansoni growth hormone secretagogue receptor 0.0039 0.0339 0.0399
Loa Loa (eye worm) ryanodine receptor 0.0014 0.0035 0.0064
Echinococcus multilocularis ferredoxin adrenodoxin 0.0012 0.0013 0.0009
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0015 0.0052 0.0062
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0064
Brugia malayi ion channel NompC 0.0014 0.0035 0.0058
Loa Loa (eye worm) hypothetical protein 0.0032 0.0252 0.0458
Schistosoma mansoni multidrug resistance protein 0.0011 0.0006 0.0007
Echinococcus granulosus g protein coupled receptor 0.0039 0.0339 0.0394
Loa Loa (eye worm) hypothetical protein 0.0013 0.0032 0.0058
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0182 0.035
Plasmodium falciparum thioredoxin reductase 0.0201 0.2261 0.4329
Brugia malayi jmjC domain containing protein 0.0016 0.007 0.0123
Mycobacterium ulcerans hypothetical protein 0.0167 0.186 0.5361
Mycobacterium ulcerans hypothetical protein 0.0025 0.017 0.0477
Loa Loa (eye worm) hypothetical protein 0.0016 0.007 0.0127
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0323 0.0319
Loa Loa (eye worm) hypothetical protein 0.0014 0.0036 0.0066
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Loa Loa (eye worm) thioredoxin reductase 0.045 0.5217 0.947
Echinococcus granulosus TRP transient receptor potential channel 0.0014 0.0035 0.0037
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.051 0.1203
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0238 0.0554
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.032 0.075
Plasmodium vivax PST-A protein 0.0026 0.0182 0.035
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0074 0.0082
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0014 0.0035 0.0058
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0123 0.1334 0.1567
Plasmodium vivax PST-A protein 0.0026 0.0182 0.035
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0303 0.3466 0.8248
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.0339 0.0394
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0336 0.0332
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0053 0.0508 0.0965
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0037 0.0063
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0064
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0052 0.0062
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0015 0.0056 0.0159
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0139 0.0163
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0014 0.0035 0.0058
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0254 0.025
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.012
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0015 0.0056 0.0097
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0039 0.0339 0.0335
Echinococcus multilocularis multidrug resistance protein 1 0.0011 0.0006 0.0001
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0076 0.0772 0.1472
Loa Loa (eye worm) melatonin receptor type 1A 0.0039 0.0339 0.0615
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0016 0.0066 0.0116
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.0252 0.0248
Loa Loa (eye worm) hypothetical protein 0.0021 0.012 0.0218
Trichomonas vaginalis glutathione reductase, putative 0.0201 0.2261 0.5376
Schistosoma mansoni voltage-gated potassium channel 0.0053 0.0508 0.0598
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0123 0.1335 0.2551
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0015 0.0056 0.0107
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0252 0.0474
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0012 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.004 0.0354 0.0643
Loa Loa (eye worm) hypothetical protein 0.0028 0.0204 0.0371
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0162 0.18 0.3444
Loa Loa (eye worm) hypothetical protein 0.0047 0.0427 0.0774
Trichomonas vaginalis receptor histidine kinase, putative 0.0015 0.0056 0.012
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0201 0.2261 0.4329
Schistosoma mansoni amine GPCR 0.0039 0.0339 0.0399
Echinococcus multilocularis G protein coupled receptor 139 0.0039 0.0339 0.0335
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0435 0.0826
Echinococcus granulosus voltage gated potassium channel 0.0022 0.0139 0.0159
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0021 0.0121 0.0222
Schistosoma mansoni ap endonuclease 0.002 0.0109 0.0128
Toxoplasma gondii hypothetical protein 0.0014 0.0035 0.0068
Trypanosoma cruzi metacaspase, putative 0.0047 0.0426 0.0809
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.051 0.097
Schistosoma mansoni inositol monophosphatase 0.0039 0.0335 0.0395
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0404 0.0766
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0201 0.2261 1
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0014 0.0035 0.0058
Echinococcus multilocularis microtubule associated protein 2 0.0726 0.8491 0.8491
Trypanosoma brucei electron transfer protein, putative 0.0012 0.0013 0.0016
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0014 0.0035 0.0031
Mycobacterium ulcerans DNA polymerase IV 0.0063 0.0628 0.1799
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0016 0.0066 0.012
Brugia malayi hypothetical protein 0.0039 0.0339 0.064
Echinococcus granulosus RUN 0.0021 0.012 0.0137
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0201 0.2261 0.4329
Echinococcus granulosus potassium voltage gated channel protein 0.0014 0.0035 0.0037
Brugia malayi Cyclic-nucleotide gated cation channel 0.0019 0.0096 0.0174
Brugia malayi steroid hormone receptor 0.0032 0.0252 0.0474
Loa Loa (eye worm) G-protein coupled receptor 0.0039 0.0339 0.0615
Loa Loa (eye worm) hypothetical protein 0.0039 0.0339 0.0615
Brugia malayi hypothetical protein 0.0039 0.0339 0.064
Brugia malayi hypothetical protein 0.0047 0.0427 0.0808
Onchocerca volvulus 0.0015 0.0052 0.0166
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0016 0.0063 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0435 0.1024
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0323 0.0376
Schistosoma mansoni alpha-1 adrenergic receptor 0.0039 0.0339 0.0399
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0182 0.0422
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0201 0.2261 0.4329
Leishmania major hypothetical protein, conserved 0.0053 0.0508 0.0965
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0012 0.0013 0.0009
Brugia malayi cation channel family protein 0.0014 0.0035 0.0058
Loa Loa (eye worm) hypothetical protein 0.0032 0.0252 0.0458
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0015 0.0051 0.0133
Schistosoma mansoni DNA topoisomerase II 0.0294 0.337 0.3969
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0081 0.0831 0.1585
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0006 0.0002
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0035 0.0042
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.051 0.0506
Trypanosoma brucei DNA topoisomerase III, putative 0.0016 0.0063 0.0111
Schistosoma mansoni rab6-interacting 0.0021 0.012 0.0141
Echinococcus granulosus alpha 1A adrenergic receptor 0.0039 0.0339 0.0394
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0053 0.0508 0.22
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0318 0.3645 0.6985
Schistosoma mansoni opsin-like receptor 0.0039 0.0339 0.0399
Leishmania major DNA polymerase kappa, putative 0.0042 0.0378 0.0716
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0052 0.0048
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0018 0.009 0.0101
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0053 0.0508 0.0965
Schistosoma mansoni thyroid hormone receptor 0.0164 0.1825 0.2149
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0406 0.0955
Loa Loa (eye worm) inositol-1 0.0039 0.0335 0.0608
Treponema pallidum DNA topoisomerase I (topA) 0.0016 0.0063 0.0177
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0053 0.0508 0.1196
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0199 0.056
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.007 0.0077
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.0252 0.0293
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0435 0.0826
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0201 0.2261 0.4329
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0015 0.0051 0.0133
Plasmodium falciparum esterase, putative 0.031 0.3555 0.681
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.051 0.0506

Activities

Activity type Activity value Assay description Source Reference
Analgesic efficacy (functional) = 34 % Analagesic activity as percentage analgesic efficacy on male albino swiss-webster mice with the hot-plate test ChEMBL. 8201605
ED50 (functional) = 28 mg kg-1 Analagesic activity after subcutaneous administration in male albino swiss-webster mice with the hot-plate test ChEMBL. 8201605

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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