Detailed information for compound 681535

Basic information

Technical information
  • TDR Targets ID: 681535
  • Name: 2,5-difluoro-N-(1-thiophen-2-ylsulfonyl-3,4-d ihydro-2H-quinolin-7-yl)benzenesulfonamide
  • MW: 470.533 | Formula: C19H16F2N2O4S3
  • H donors: 1 H acceptors: 4 LogP: 3.76 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(c(c1)S(=O)(=O)Nc1ccc2c(c1)N(CCC2)S(=O)(=O)c1cccs1)F
  • InChi: 1S/C19H16F2N2O4S3/c20-14-6-8-16(21)18(11-14)29(24,25)22-15-7-5-13-3-1-9-23(17(13)12-15)30(26,27)19-4-2-10-28-19/h2,4-8,10-12,22H,1,3,9H2
  • InChiKey: IVDBHOZKNIGQQR-UHFFFAOYSA-N  

Network

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Synonyms

  • 2,5-difluoro-N-[1-(2-thienylsulfonyl)-3,4-dihydro-2H-quinolin-7-yl]benzenesulfonamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0514 0.0514
Brugia malayi F/Y-rich N-terminus family protein 0.0039 0.0588 0.0588
Schistosoma mansoni cpg binding protein 0.0031 0.0387 0.0387
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0024 0.0236 0.0236
Schistosoma mansoni phd/f-box containing protein 0.0029 0.0357 0.0357
Loa Loa (eye worm) TYRA-2 protein 0.0024 0.0236 0.0236
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0024 0.0236 0.0236
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0236 0.0236
Echinococcus multilocularis peregrin 0.009 0.1724 0.1724
Echinococcus multilocularis importin subunit beta 1 0.003 0.038 0.038
Echinococcus multilocularis para nitrobenzyl esterase 0.0078 0.1445 0.1445
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Echinococcus granulosus serotonin receptor 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Mycobacterium ulcerans short chain dehydrogenase 0.0449 0.9748 1
Echinococcus granulosus neuropeptide Y receptor 0.0024 0.0236 0.0236
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0649 0.0823
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0236 0.0236
Schistosoma mansoni alpha-1 adrenergic receptor 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.015 0.3062 0.3062
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0236 0.0236
Brugia malayi hypothetical protein 0.0024 0.0236 0.0236
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0024 0.0236 0.0236
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0296 0.6318 0.6318
Schistosoma mansoni opsin-like receptor 0.0024 0.0236 0.0236
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0365 0.7098
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Schistosoma mansoni cpg binding protein 0.0029 0.035 0.035
Mycobacterium tuberculosis Conserved protein 0.0036 0.0514 0.0527
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0031 0.0393 0.0393
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0514 1
Mycobacterium ulcerans beta-lactamase 0.0036 0.0514 0.0527
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0024 0.0236 0.0236
Onchocerca volvulus 0.0078 0.1445 0.2405
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0108 0.0204
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0236 0.0236
Echinococcus multilocularis acetylcholinesterase 0.0461 1 1
Brugia malayi Serotonin receptor 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Schistosoma mansoni neuropeptide F-like receptor 0.0024 0.0236 0.0236
Mycobacterium leprae Probable lipase LipE 0.0036 0.0514 0.5
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Echinococcus granulosus neuropeptide receptor A26 0.0024 0.0236 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0583 0.1108
Echinococcus granulosus jumonji domain containing protein 0.0126 0.2515 0.2515
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.003 0.0365 0.2117
Echinococcus multilocularis fmrfamide receptor 0.0024 0.0236 0.0236
Echinococcus multilocularis neuroligin 0.0078 0.1445 0.1445
Loa Loa (eye worm) hypothetical protein 0.0078 0.1445 0.1445
Plasmodium vivax importin-beta 2, putative 0.003 0.038 0.2201
Echinococcus multilocularis phd:f box containing protein 0.0029 0.0357 0.0357
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0236 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0326 0.0621
Echinococcus granulosus lysine specific demethylase 5A 0.0111 0.2186 0.2186
Echinococcus granulosus fmrfamide receptor 0.0024 0.0236 0.0236
Schistosoma mansoni neuropeptide receptor 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0108 0.0204
Plasmodium vivax hypothetical protein, conserved 0.009 0.1724 1
Echinococcus granulosus g protein coupled receptor 0.0024 0.0236 0.0236
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0236 0.0236
Echinococcus multilocularis neuropeptides capa receptor 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0078 0.1445 0.1445
Brugia malayi chromobox protein homolog 3 0.0039 0.0583 0.0583
Brugia malayi jmjC domain containing protein 0.0029 0.0357 0.0357
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0236 0.0236
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0236 0.0236
Echinococcus multilocularis neuropeptide receptor A26 0.0024 0.0236 0.0236
Brugia malayi jmjC domain containing protein 0.0029 0.0357 0.0357
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0514 0.5
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0036 0.0514 0.0514
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0514 0.0514
Echinococcus granulosus geminin 0.017 0.3513 0.3513
Trichomonas vaginalis set domain proteins, putative 0.0249 0.526 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0417 0.0417
Echinococcus granulosus neuropeptide receptor 0.0024 0.0236 0.0236
Echinococcus multilocularis dro:myosuppressin receptor 0.0024 0.0236 0.0236
Brugia malayi hypothetical protein 0.0078 0.1445 0.1445
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0514 0.0527
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0108 0.0204
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0365 0.7098
Echinococcus granulosus peregrin 0.009 0.1724 0.1724
Echinococcus multilocularis neuropeptide Y receptor 0.0024 0.0236 0.0236
Brugia malayi Dopamine receptor protein 2 0.0024 0.0236 0.0236
Brugia malayi neuropeptide F receptor 0.0024 0.0236 0.0236
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0108 0.0204
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0024 0.0236 0.0236
Schistosoma mansoni hypothetical protein 0.009 0.1724 0.1724
Schistosoma mansoni amine GPCR 0.0024 0.0236 0.0236
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0461 1 1
Leishmania major hypothetical protein, conserved 0.0036 0.0514 1
Brugia malayi Pre-SET motif family protein 0.0032 0.0417 0.0417
Echinococcus multilocularis muscleblind protein 1 0.015 0.3062 0.3062
Echinococcus multilocularis allatostatin A receptor 0.0024 0.0236 0.0236
Schistosoma mansoni hypothetical protein 0.003 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Toxoplasma gondii PHD-finger domain-containing protein 0.009 0.1724 1
Echinococcus granulosus lysine specific demethylase 6a 0.0029 0.0357 0.0357
Schistosoma mansoni tar DNA-binding protein 0.0055 0.094 0.094
Schistosoma mansoni biogenic amine receptor 0.0024 0.0236 0.0236
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0024 0.0236 0.0236
Plasmodium vivax JmjC domain containing protein 0.0029 0.0357 0.2069
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0236 0.0236
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0236 0.0236
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0649 0.1235
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0024 0.0236 0.0236
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0043 0.0674 0.0674
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Brugia malayi Carboxylesterase family protein 0.0078 0.1445 0.1445
Brugia malayi jmjC domain containing protein 0.0029 0.0357 0.0357
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0236 0.0236
Loa Loa (eye worm) jmjC domain-containing protein 0.0111 0.2186 0.2186
Plasmodium falciparum importin beta, putative 0.003 0.038 0.2201
Echinococcus multilocularis chromobox protein 1 0.007 0.1271 0.1271
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0236 0.0236
Schistosoma mansoni tar DNA-binding protein 0.0055 0.094 0.094
Schistosoma mansoni importin beta-1 0.003 0.038 0.038
Onchocerca volvulus 0.0036 0.0514 0.0554
Brugia malayi larval opioid receptor 0.0024 0.0236 0.0236
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0108 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0326 0.0621
Brugia malayi hypothetical protein 0.0024 0.0236 0.0236
Echinococcus multilocularis jumonji domain containing 1A 0.0029 0.0357 0.0357
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0514 0.0527
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0514 0.0514
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0236 0.0236
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0514 0.0977
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0108 0.0204
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Brugia malayi Bromodomain containing protein 0.009 0.1724 0.1724
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0024 0.0236 0.0236
Schistosoma mansoni hypothetical protein 0.0024 0.0236 0.0236
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0108 0.0204
Echinococcus multilocularis snurportin 1 0.0322 0.6905 0.6905
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0024 0.0236 0.0236
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0357 0.0357
Schistosoma mansoni hypothetical protein 0.0024 0.0236 0.0236
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0236 0.0236
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0236 0.0236
Giardia lamblia PHD finger protein 15 0.009 0.1724 1
Echinococcus granulosus carboxylesterase 5A 0.0461 1 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0201 0.1168
Leishmania major GTP-binding protein, putative 0.0022 0.0201 0.3918
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0514 0.0527
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Echinococcus multilocularis neuropeptide s receptor 0.0024 0.0236 0.0236
Brugia malayi sulfakinin receptor protein 0.0024 0.0236 0.0236
Loa Loa (eye worm) PHD-finger family protein 0.009 0.1724 0.1724
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0024 0.0236 0.0236
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0024 0.0236 0.0236
Brugia malayi Pre-SET motif family protein 0.0218 0.4587 0.4587
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Echinococcus multilocularis lysine specific demethylase 5A 0.0109 0.2149 0.2149
Brugia malayi Dopamine receptor 0.0024 0.0236 0.0236
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0201 0.3918
Schistosoma mansoni biogenic amine receptor 0.0024 0.0236 0.0236
Trichomonas vaginalis ran, putative 0.0022 0.0201 0.0383
Brugia malayi RE15519p 0.0024 0.0236 0.0236
Loa Loa (eye worm) acetylcholinesterase 1 0.0461 1 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0024 0.0236 0.0236
Echinococcus granulosus muscleblind protein 0.015 0.3062 0.3062
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0357 0.0357
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0583 0.1108
Schistosoma mansoni hypothetical protein 0.017 0.3513 0.3513
Echinococcus multilocularis G-protein coupled receptor, putative 0.0024 0.0236 0.0236
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0024 0.0236 0.0236
Mycobacterium ulcerans carboxylesterase, LipT 0.0078 0.1445 0.1482
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0236 0.0236
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0024 0.0236 0.0236
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0024 0.0236 0.0236
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0029 0.0357 0.6938
Brugia malayi beta-lactamase 0.0036 0.0514 0.0514
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0038 0.0551 0.0551
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0029 0.0357 0.0357
Schistosoma mansoni amine GPCR 0.0024 0.0236 0.0236
Brugia malayi follicle stimulating hormone receptor 0.0024 0.0236 0.0236
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0514 0.0977
Schistosoma mansoni neuropeptide f receptor 76f 0.0024 0.0236 0.0236
Schistosoma mansoni opsin-like receptor 0.0024 0.0236 0.0236
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0514 0.0527
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0024 0.0236 0.0236
Onchocerca volvulus 0.0078 0.1445 0.2405
Trichomonas vaginalis chromobox protein, putative 0.007 0.1271 0.2416
Brugia malayi GnHR receptor homolog 0.0024 0.0236 0.0236
Echinococcus granulosus 7TM GPCR rhodopsin 0.0024 0.0236 0.0236
Echinococcus granulosus tachykinin peptides receptor 99D 0.0024 0.0236 0.0236
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0514 0.0977
Echinococcus granulosus JmjC domain containing protein 4 0.0029 0.0357 0.0357
Echinococcus granulosus neuropeptide FF receptor 2 0.0024 0.0236 0.0236
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.038 0.2201
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0236 0.0236
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0231 0.4874 0.5
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0417 0.2421
Schistosoma mansoni neuropeptide receptor 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0417 0.0417
Brugia malayi Importin beta-1 subunit 0.003 0.038 0.038
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0583 0.069
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0514 0.0527
Loa Loa (eye worm) hypothetical protein 0.0036 0.0514 0.0514
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0514 0.0977
Echinococcus granulosus biogenic amine 5HT receptor 0.0024 0.0236 0.0236
Echinococcus granulosus sex peptide receptor 0.0024 0.0236 0.0236
Echinococcus multilocularis tar DNA binding protein 0.0055 0.094 0.094
Loa Loa (eye worm) carboxylesterase 0.0078 0.1445 0.1445
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0514 0.2982
Echinococcus multilocularis neuropeptide receptor 0.0024 0.0236 0.0236
Trichomonas vaginalis chromobox protein, putative 0.007 0.1271 0.2416
Echinococcus granulosus phd:f box containing protein 0.0029 0.0357 0.0357
Loa Loa (eye worm) hypothetical protein 0.0155 0.3167 0.3167
Schistosoma mansoni hypothetical protein 0.017 0.3513 0.3513
Schistosoma mansoni tar DNA-binding protein 0.0055 0.094 0.094
Brugia malayi G protein-coupled receptor 0.0024 0.0236 0.0236
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0078 0.1445 0.1445
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0236 0.0236
Loa Loa (eye worm) neuropeptide F receptor 0.0024 0.0236 0.0236
Echinococcus granulosus tar DNA binding protein 0.0055 0.094 0.094
Loa Loa (eye worm) TAR-binding protein 0.0055 0.094 0.094
Echinococcus multilocularis neuropeptide FF receptor 2 0.0024 0.0236 0.0236
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0218 0.4587 0.4587
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Leishmania major hypothetical protein, conserved 0.0029 0.0357 0.6938
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0236 0.0236
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0201 0.0201
Mycobacterium tuberculosis Conserved protein 0.0036 0.0514 0.0527
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Schistosoma mansoni adenoreceptor 0.0024 0.0236 0.0236
Schistosoma mansoni myosin xvIII 0.0024 0.0236 0.0236
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0108 0.0204
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Echinococcus granulosus PHD finger protein rhinoceros 0.009 0.1724 0.1724
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Brugia malayi Serotonin receptor 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0036 0.0514 0.0514
Schistosoma mansoni amine GPCR 0.0024 0.0236 0.0236
Loa Loa (eye worm) RNA binding protein 0.0055 0.094 0.094
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Brugia malayi Carboxylesterase family protein 0.0078 0.1445 0.1445
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0236 0.0236
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0024 0.0236 0.0236
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0236 0.0236
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0029 0.0357 0.2069
Echinococcus granulosus snurportin 1 0.0322 0.6905 0.6905
Brugia malayi RNA recognition motif domain containing protein 0.0055 0.094 0.094
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.004 0.0076
Loa Loa (eye worm) G-protein coupled receptor 0.0024 0.0236 0.0236
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0417 0.0417
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0322 0.6905 0.6905
Echinococcus granulosus neuropeptides capa receptor 0.0024 0.0236 0.0236
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0024 0.0236 0.0236
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0024 0.0236 0.0236
Schistosoma mansoni amine GPCR 0.0024 0.0236 0.0236
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0031 0.0394 0.0394
Echinococcus multilocularis fmrfamide receptor 0.0024 0.0236 0.0236
Brugia malayi jmjC domain containing protein 0.0111 0.2186 0.2186
Onchocerca volvulus Alhambra homolog 0.009 0.1724 0.2962
Brugia malayi neuropeptide F receptor 0.0024 0.0236 0.0236
Echinococcus granulosus dnaJ subfamily B 0.0411 0.8897 0.8897
Echinococcus multilocularis serotonin receptor 0.0024 0.0236 0.0236
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0024 0.0236 0.0236
Brugia malayi Carboxylesterase family protein 0.0078 0.1445 0.1445
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0201 0.0201
Echinococcus granulosus somatostatin receptor 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Brugia malayi hypothetical protein 0.0024 0.0236 0.0236
Entamoeba histolytica Ran family GTPase 0.0022 0.0201 0.7995
Schistosoma mansoni hypothetical protein 0.0024 0.0236 0.0236
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0461 1 1
Schistosoma mansoni acetylcholinesterase 0.0078 0.1445 0.1445
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0031 0.0404 0.2345
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0201 0.1168
Brugia malayi jmjC domain containing protein 0.0296 0.6318 0.6318
Brugia malayi TAR-binding protein 0.0055 0.094 0.094
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0417 0.0417
Loa Loa (eye worm) hypothetical protein 0.0078 0.1445 0.1445
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0236 0.0236
Loa Loa (eye worm) neuropeptide F receptor 0.0024 0.0236 0.0236
Schistosoma mansoni opsin-like receptor 0.0024 0.0236 0.0236
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0201 0.3918
Echinococcus multilocularis sex peptide receptor 0.0024 0.0236 0.0236
Schistosoma mansoni ran 0.0022 0.0201 0.0201
Echinococcus granulosus biogenic amine 5HT receptor 0.0024 0.0236 0.0236
Schistosoma mansoni biogenic amine (5HT) receptor 0.0024 0.0236 0.0236
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.038 0.7381
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0236 0.0236
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0417 0.0417
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Echinococcus granulosus g protein coupled receptor 0.0024 0.0236 0.0236
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0514 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0024 0.0236 0.0236
Brugia malayi RNA, U transporter 1 0.0086 0.1623 0.1623
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0024 0.0236 0.0236
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0024 0.0236 0.0236
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0252 0.0479
Echinococcus multilocularis carboxylesterase 5A 0.0461 1 1
Loa Loa (eye worm) carboxylesterase 0.0078 0.1445 0.1445
Brugia malayi Dopamine receptor protein 1 0.0024 0.0236 0.0236
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0024 0.0236 0.0236
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0024 0.0236 0.0236
Schistosoma mansoni tar DNA-binding protein 0.0055 0.094 0.094
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0201 0.1168
Brugia malayi beta-lactamase family protein 0.0036 0.0514 0.0514
Echinococcus multilocularis PHD finger protein rhinoceros 0.009 0.1724 0.1724
Brugia malayi PHD-finger family protein 0.0031 0.0402 0.0402
Echinococcus multilocularis BC026374 protein (S09 family) 0.0078 0.1445 0.1445
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0055 0.094 0.094
Loa Loa (eye worm) hypothetical protein 0.003 0.038 0.038
Echinococcus granulosus chromobox protein 1 0.007 0.1271 0.1271
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0078 0.1445 0.1445
Brugia malayi putative neuropeptide receptor 0.0024 0.0236 0.0236
Echinococcus granulosus 7tm_1 domain containing protein 0.0024 0.0236 0.0236
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0029 0.0357 0.6938
Plasmodium falciparum JmjC domain-containing protein, putative 0.0029 0.0357 0.2069
Schistosoma mansoni ran 0.0022 0.0201 0.0201
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0024 0.0236 0.0236
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0029 0.0357 0.2069
Echinococcus multilocularis serotonin receptor 0.0024 0.0236 0.0236
Brugia malayi putative neuropeptide receptor NPR1 0.0024 0.0236 0.0236
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0024 0.0236 0.0236
Echinococcus granulosus neuroligin 0.0078 0.1445 0.1445
Brugia malayi CXXC zinc finger family protein 0.0029 0.035 0.035
Echinococcus granulosus hypothetical protein 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.015 0.3062 0.3062
Echinococcus granulosus allatostatin A receptor 0.0024 0.0236 0.0236
Schistosoma mansoni hypothetical protein 0.0411 0.8897 0.8897
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0514 0.0527
Brugia malayi Carboxylesterase family protein 0.0078 0.1445 0.1445
Echinococcus granulosus neuropeptide Y receptor 0.0024 0.0236 0.0236
Schistosoma mansoni growth hormone secretagogue receptor 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0078 0.1445 0.1445
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0514 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0357 0.0357
Loa Loa (eye worm) hypothetical protein 0.0031 0.0402 0.0402
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.004 0.0076
Schistosoma mansoni hypothetical protein 0.0322 0.6905 0.6905
Echinococcus granulosus acetylcholinesterase 0.0461 1 1
Echinococcus granulosus g-protein coupled receptor 0.0024 0.0236 0.0236
Echinococcus multilocularis neuropeptide Y receptor 0.0024 0.0236 0.0236
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0514 0.0527
Echinococcus granulosus peptide allatostatin:somatostatin 0.0024 0.0236 0.0236
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0252 0.0479
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.1271 0.1271
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0514 0.0514
Plasmodium vivax SET domain protein, putative 0.0032 0.0417 0.2421
Schistosoma mansoni hypothetical protein 0.0024 0.0236 0.0236
Brugia malayi hypothetical protein 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0029 0.0357 0.0357
Toxoplasma gondii PHD-finger domain-containing protein 0.009 0.1724 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0029 0.0055
Echinococcus granulosus cpg binding protein 0.0031 0.0387 0.0387
Loa Loa (eye worm) hypothetical protein 0.0078 0.1445 0.1445
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0201 0.3918
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0078 0.1445 0.1445
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0252 0.49
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.11 0.11
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0236 0.0236
Brugia malayi hypothetical protein 0.0024 0.0236 0.0236
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0024 0.0236 0.0236
Brugia malayi Muscleblind-like protein 0.015 0.3062 0.3062
Echinococcus multilocularis orexin receptor type 2 0.0024 0.0236 0.0236
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0252 0.0479
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0024 0.0236 0.0236
Echinococcus multilocularis muscleblind protein 0.015 0.3062 0.3062
Loa Loa (eye worm) hypothetical protein 0.0036 0.0514 0.0514
Brugia malayi AF-10 protein 0.003 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Schistosoma mansoni neuropeptide F-like receptor 0.0024 0.0236 0.0236
Echinococcus multilocularis G protein coupled receptor 139 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0649 0.1235
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0024 0.0236 0.0236
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0078 0.1445 0.1445
Echinococcus multilocularis dnaJ subfamily B 0.0411 0.8897 0.8897
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0404 0.2345
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0236 0.0236
Echinococcus granulosus para nitrobenzyl esterase 0.0078 0.1445 0.1445
Brugia malayi Melatonin receptor type 1A 0.0024 0.0236 0.0236
Echinococcus granulosus dro:myosuppressin receptor 0.0024 0.0236 0.0236
Brugia malayi AKH receptor 0.0024 0.0236 0.0236
Echinococcus granulosus neuropeptide s receptor 0.0024 0.0236 0.0236
Echinococcus granulosus acetylcholinesterase 0.0461 1 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0031 0.0394 0.0394
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0514 0.0514
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0236 0.0236
Schistosoma mansoni jumonji/arid domain-containing protein 0.0111 0.2186 0.2186
Onchocerca volvulus 0.0036 0.0514 0.0554
Brugia malayi ORL1-like opioid receptor 0.0024 0.0236 0.0236
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0078 0.1445 0.1445
Mycobacterium tuberculosis Conserved protein 0.0036 0.0514 0.0527
Onchocerca volvulus 0.0031 0.0393 0.0313
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0236 0.0236
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0201 0.0201
Schistosoma mansoni neuroligin 3 (S09 family) 0.0078 0.1445 0.1445
Brugia malayi SET domain containing protein 0.0013 0.0001 0.0001
Mycobacterium ulcerans lipase LipD 0.0036 0.0514 0.0527
Echinococcus multilocularis neuropeptide receptor 0.0024 0.0236 0.0236
Onchocerca volvulus 0.0249 0.526 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0378 0.0378
Echinococcus multilocularis cpg binding protein 0.0031 0.0387 0.0387
Loa Loa (eye worm) melatonin receptor type 1A 0.0024 0.0236 0.0236
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0029 0.0357 0.6938
Echinococcus granulosus chromobox protein 1 0.007 0.1271 0.1271
Schistosoma mansoni jumonji/arid domain-containing protein 0.0111 0.2186 0.2186
Schistosoma mansoni tar DNA-binding protein 0.0055 0.094 0.094
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0236 0.0236
Brugia malayi hypothetical protein 0.0024 0.0236 0.0236
Echinococcus multilocularis g-protein coupled receptor 0.0024 0.0236 0.0236
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0024 0.0236 0.0236
Schistosoma mansoni histamine h1 receptor 0.0024 0.0236 0.0236
Schistosoma mansoni protein phosphatase 2C 0.0029 0.0357 0.0357
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0201 0.0201
Schistosoma mansoni jumonji domain containing protein 0.0029 0.0357 0.0357
Onchocerca volvulus 0.0078 0.1445 0.2405
Brugia malayi hypothetical protein 0.0024 0.0236 0.0236
Echinococcus multilocularis jumonji domain containing protein 0.0126 0.2515 0.2515
Plasmodium falciparum phd finger protein, putative 0.009 0.1724 1
Trichomonas vaginalis spcc417.12 protein, putative 0.0078 0.1445 0.2746
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0357 0.0357
Echinococcus granulosus G protein coupled receptor 139 0.0024 0.0236 0.0236
Schistosoma mansoni amine GPCR 0.0024 0.0236 0.0236
Echinococcus granulosus jumonji domain containing 1A 0.0029 0.0357 0.0357
Loa Loa (eye worm) G-protein coupled receptor 0.0024 0.0236 0.0236
Echinococcus granulosus BC026374 protein S09 family 0.0078 0.1445 0.1445
Schistosoma mansoni cpg binding protein 0.0031 0.0387 0.0387
Schistosoma mansoni neuropeptide receptor 0.0024 0.0236 0.0236
Echinococcus granulosus importin subunit beta 1 0.003 0.038 0.038
Entamoeba histolytica hypothetical protein 0.0024 0.0252 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0078 0.1445 0.2746
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0078 0.1445 0.1482
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0514 0.0977
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0417 0.0417
Mycobacterium tuberculosis Carboxylesterase LipT 0.0078 0.1445 0.1482
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0013 0 0.5
Schistosoma mansoni biogenic amine (5HT) receptor 0.0024 0.0236 0.0236
Brugia malayi hypothetical protein 0.0024 0.0236 0.0236
Schistosoma mansoni neuropeptide receptor 0.0024 0.0236 0.0236
Echinococcus multilocularis somatostatin receptor 0.0024 0.0236 0.0236
Brugia malayi PHD-finger family protein 0.009 0.1724 0.1724
Onchocerca volvulus 0.0078 0.1445 0.2405
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0236 0.0236
Mycobacterium ulcerans hypothetical protein 0.0036 0.0514 0.0527
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0514 0.0514
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0296 0.6318 0.6318
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0024 0.0236 0.0236
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0236 0.0236
Echinococcus multilocularis acetylcholinesterase 0.0461 1 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0514 0.0527
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0078 0.1445 0.1445
Trichomonas vaginalis esterase, putative 0.0036 0.0514 0.0977
Mycobacterium tuberculosis Probable oxidoreductase 0.0449 0.9748 1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.009 0.1724 0.1724
Brugia malayi Carboxylesterase family protein 0.0461 1 1
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0078 0.1445 0.1482
Loa Loa (eye worm) beta-lactamase 0.0036 0.0514 0.0514
Echinococcus granulosus neuropeptide receptor 0.0024 0.0236 0.0236
Brugia malayi hypothetical protein 0.0024 0.0236 0.0236
Toxoplasma gondii ABC1 family protein 0.0036 0.0514 0.2982
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0201 0.1168
Schistosoma mansoni BC026374 protein (S09 family) 0.0078 0.1445 0.1445
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0024 0.0236 0.0236
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0514 0.0527
Loa Loa (eye worm) carboxylesterase 0.0461 1 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0036 0.0514 0.0514
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0024 0.0236 0.0236
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.038 0.7381
Echinococcus granulosus alpha 1A adrenergic receptor 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0078 0.1445 0.1445
Loa Loa (eye worm) hypothetical protein 0.009 0.1724 0.1724
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0024 0.0236 0.0236
Onchocerca volvulus 0.0078 0.1445 0.2405
Brugia malayi RNA binding protein 0.0055 0.094 0.094
Echinococcus multilocularis chromobox protein 1 0.007 0.1271 0.1271
Echinococcus granulosus orexin receptor type 2 0.0024 0.0236 0.0236
Onchocerca volvulus 0.0043 0.0674 0.0871
Echinococcus granulosus g protein coupled receptor 0.0024 0.0236 0.0236
Schistosoma mansoni gliotactin 0.0078 0.1445 0.1445
Echinococcus multilocularis neuropeptides capa receptor 0.0024 0.0236 0.0236
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0365 0.2117
Onchocerca volvulus 0.0029 0.035 0.0228
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Schistosoma mansoni biogenic amine receptor 0.0024 0.0236 0.0236
Schistosoma mansoni jumonji domain containing protein 0.0235 0.4959 0.4959
Brugia malayi jmjC domain containing protein 0.0029 0.0357 0.0357
Brugia malayi beta-lactamase family protein 0.0036 0.0514 0.0514
Schistosoma mansoni chromobox protein 0.007 0.1271 0.1271
Treponema pallidum exodeoxyribonuclease (exoA) 0.0013 0 0.5
Echinococcus multilocularis geminin 0.017 0.3513 0.3513
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0036 0.0514 0.0514
Brugia malayi hypothetical protein 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Onchocerca volvulus 0.0036 0.0514 0.0554
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.035 0.035
Loa Loa (eye worm) hypothetical protein 0.0039 0.0583 0.0583
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0024 0.0236 0.0236
Brugia malayi G-protein coupled receptor 0.0024 0.0236 0.0236
Echinococcus multilocularis JmjC domain containing protein 4 0.0029 0.0357 0.0357
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0461 1 1
Brugia malayi Heterochromatin protein 1 0.007 0.1271 0.1271
Loa Loa (eye worm) hypothetical protein 0.0032 0.0417 0.0417
Leishmania major importin beta-1 subunit, putative 0.0024 0.0252 0.49
Schistosoma mansoni phosphatidylserine receptor 0.0029 0.0357 0.0357
Loa Loa (eye worm) jmjC domain-containing protein 0.0187 0.3874 0.3874
Echinococcus granulosus neuropeptides capa receptor 0.0024 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0953 0.553
Schistosoma mansoni chromobox protein 0.007 0.1271 0.1271
Loa Loa (eye worm) hypothetical protein 0.0024 0.0236 0.0236
Echinococcus multilocularis lysine specific demethylase 6a 0.0029 0.0357 0.0357
Brugia malayi G-protein coupled receptor 0.0024 0.0236 0.0236

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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