Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0062 | 0.1287 | 0.1282 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0045 | 0.0861 | 0.2215 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0059 | 0.1226 | 0.1224 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0006 | 0.0005 |
Brugia malayi | jmjC domain containing protein | 0.0059 | 0.1226 | 0.1857 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0011 | 0.0019 | 0.0006 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0013 | 0.0069 | 0.0075 |
Schistosoma mansoni | patched 1 | 0.0068 | 0.1446 | 0.1441 |
Onchocerca volvulus | 0.0041 | 0.0785 | 0.1367 | |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0059 | 0.1226 | 0.1224 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0035 | 0.0616 | 0.1588 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.002 | 0.0249 | 0.2756 |
Schistosoma mansoni | DNA polymerase eta | 0.0015 | 0.0115 | 0.011 |
Trypanosoma cruzi | metacaspase, putative | 0.0045 | 0.0861 | 0.2215 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.002 | 0.0249 | 0.2756 |
Trypanosoma brucei | Metacaspase-4 | 0.0045 | 0.0861 | 0.2221 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0384 | 0.098 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0006 | 0.0009 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0006 | 0.0005 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.0249 | 0.192 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0066 | 0.1407 | 0.3633 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0224 | 0.255 |
Echinococcus multilocularis | protein patched | 0.0068 | 0.1446 | 0.1444 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0006 | 0.0005 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0384 | 0.098 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0513 | 0.0508 |
Schistosoma mansoni | glutaminase | 0.0275 | 0.6601 | 0.6599 |
Onchocerca volvulus | 0.0029 | 0.0472 | 0.0819 | |
Onchocerca volvulus | Eukaryotic initiation factor 4A homolog | 0.0011 | 0.0017 | 0.0019 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0011 | 0.0019 | 0.0006 |
Echinococcus multilocularis | caspase 3 | 0.0073 | 0.1575 | 0.1572 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0513 | 0.0508 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0224 | 0.0218 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0045 | 0.0861 | 0.1196 |
Giardia lamblia | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0.0078 | 0.1683 | 0.236 |
Echinococcus multilocularis | caspase 2 | 0.0086 | 0.1893 | 0.1891 |
Plasmodium falciparum | LCCL domain-containing protein | 0.002 | 0.0247 | 0.2725 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0066 | 0.1407 | 0.1402 |
Schistosoma mansoni | jumonji domain containing protein | 0.0016 | 0.0146 | 0.014 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0152 | 0.3525 | 0.5338 |
Chlamydia trachomatis | two component regulatory system sensor histidine kinase | 0.0013 | 0.0069 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0006 | 0.0009 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0016 | 0.0146 | 0.0143 |
Schistosoma mansoni | DNA helicase recq1 | 0.002 | 0.0249 | 0.0244 |
Schistosoma mansoni | subfamily C14A unassigned peptidase (C14 family) | 0.0045 | 0.0861 | 0.0856 |
Plasmodium falciparum | metacaspase-like protein | 0.0045 | 0.0861 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0861 | 0.1196 |
Schistosoma mansoni | hypothetical protein | 0.0412 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0006 | 0.0003 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0146 | 0.3384 | 0.338 |
Echinococcus multilocularis | dna polymerase kappa | 0.0041 | 0.0782 | 0.0779 |
Leishmania major | cytochrome p450-like protein | 0.002 | 0.0238 | 0.0576 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.002 | 0.0247 | 0.0244 |
Brugia malayi | Doublecortin family protein | 0.002 | 0.0247 | 0.0374 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0006 | 0.0003 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0006 | 0.0003 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0015 | 0.0115 | 0.0113 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0006 | 0.0009 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.002 | 0.0249 | 0.0246 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0165 | 0.3866 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0017 | 0.0021 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0015 | 0.0115 | 0.0298 |
Trichomonas vaginalis | protein kinase inhibitor, putative | 0.0062 | 0.1287 | 0.18 |
Schistosoma mansoni | tyrosine kinase | 0.0059 | 0.1219 | 0.1214 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.002 | 0.0238 | 0.0333 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0115 | 0.017 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0011 | 0.0019 | 0.0006 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0068 | 0.1446 | 0.1441 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0078 | 0.1683 | 0.236 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0066 | 0.1407 | 0.361 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0006 | 0.0005 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.0086 | 0.1893 | 0.3313 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0146 | 0.0216 |
Leishmania major | protein kinase, putative | 0.0013 | 0.0069 | 0.0137 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0294 | 0.7075 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.002 | 0.0238 | 0.0602 |
Schistosoma mansoni | jumonji domain containing protein | 0.0059 | 0.1226 | 0.1221 |
Brugia malayi | mucosa associated lymphoid tissue lymphoma translocation protein 1 | 0.0045 | 0.0861 | 0.1304 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0006 | 0.0009 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0039 | 0.0732 | 0.1013 |
Brugia malayi | glutaminase DH11.1 | 0.0275 | 0.6601 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0006 | 0.0009 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.002 | 0.0249 | 0.0638 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0861 | 0.1196 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0294 | 0.7075 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0.0516 | 0.0514 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0294 | 0.7075 | 1 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0045 | 0.0861 | 0.1196 |
Trypanosoma cruzi | metacaspase, putative | 0.0045 | 0.0861 | 0.2215 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0224 | 0.0626 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0006 | 0.0003 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0006 | 0.0003 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.0165 | 0.3866 | 0.5845 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0006 | 0.0009 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0006 | 0.0003 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.021 | 0.4982 | 0.7547 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0016 | 0.0146 | 0.1103 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0011 | 0.0019 | 0.0033 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0078 | 0.1683 | 0.236 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0516 | 0.0514 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0056 | 0.1136 | 0.1133 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0013 | 0.0069 | 0.0165 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.0146 | 0.0221 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0516 | 0.0514 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0165 | 0.3866 | 1 |
Onchocerca volvulus | 0.0239 | 0.5703 | 1 | |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0473 | 0.047 |
Echinococcus granulosus | bloom syndrome protein | 0.002 | 0.0249 | 0.0246 |
Echinococcus multilocularis | RUN | 0.002 | 0.0247 | 0.0244 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0016 | 0.0146 | 0.014 |
Giardia lamblia | DINP protein human, muc B family | 0.0021 | 0.0281 | 0.0374 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0294 | 0.7075 | 1 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0068 | 0.1446 | 0.1444 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0187 | 0.4397 | 0.6659 |
Echinococcus granulosus | phd:f box containing protein | 0.0016 | 0.0146 | 0.0143 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0294 | 0.7075 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0006 | 0.0003 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0006 | 0.0003 |
Onchocerca volvulus | 0.0036 | 0.0655 | 0.1139 | |
Echinococcus multilocularis | eukaryotic initiation factor 4A III | 0.0011 | 0.0017 | 0.0014 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0068 | 0.1446 | 0.2026 |
Echinococcus multilocularis | bloom syndrome protein | 0.002 | 0.0249 | 0.0246 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0011 | 0.0019 | 0.0016 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.002 | 0.0247 | 0.2817 |
Schistosoma mansoni | loxhd1 | 0.002 | 0.0247 | 0.0241 |
Mycobacterium leprae | Possible regulatory protein | 0.0013 | 0.0069 | 0.0153 |
Echinococcus granulosus | apoptotic protease activating factor 1 | 0.0041 | 0.0785 | 0.0782 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0011 | 0.0019 | 0.0102 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0045 | 0.0861 | 0.6743 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0049 | 0.0971 | 0.0966 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0013 | 0.0069 | 0.0165 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0006 | 0.0003 |
Trypanosoma brucei | cytochrome P450, putative | 0.002 | 0.0238 | 0.0609 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.0249 | 0.0378 |
Onchocerca volvulus | 0.002 | 0.0247 | 0.0423 | |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0782 | 0.2009 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0006 | 0.0003 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0062 | 0.1287 | 0.1926 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.002 | 0.0247 | 0.0244 |
Schistosoma mansoni | tyrosine kinase | 0.01 | 0.2236 | 0.2231 |
Trypanosoma cruzi | cytochrome P450, putative | 0.002 | 0.0238 | 0.0602 |
Schistosoma mansoni | lipoxygenase | 0.002 | 0.0247 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.3841 | 0.5818 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0011 | 0.0031 | 0.0195 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0013 | 0.0069 | 0.0075 |
Echinococcus granulosus | dnaJ subfamily C 6 | 0.0062 | 0.1287 | 0.1285 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0068 | 0.1446 | 0.1444 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.0165 | 0.3866 | 0.3863 |
Loa Loa (eye worm) | doublecortin family protein | 0.002 | 0.0247 | 0.037 |
Entamoeba histolytica | recQ family helicase, putative | 0.002 | 0.0249 | 0.0344 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0006 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0006 | 0.0005 |
Schistosoma mansoni | thyroid hormone receptor | 0.0137 | 0.316 | 0.3156 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0016 | 0.0146 | 0.0143 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0006 | 0.0009 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0861 | 0.1196 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0861 | 0.1196 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.1306 | 0.1301 |
Trypanosoma brucei | metacaspase 5, putative | 0.0045 | 0.0861 | 0.2221 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0224 | 0.0565 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0782 | 0.2016 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0059 | 0.1226 | 0.1224 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0066 | 0.1407 | 0.1981 |
Schistosoma mansoni | phd/f-box containing protein | 0.0016 | 0.0146 | 0.014 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0045 | 0.0861 | 0.1196 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0011 | 0.0019 | 0.0006 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0011 | 0.0017 | 0.0011 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0062 | 0.1287 | 0.1284 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0247 | 0.037 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0006 | 0.0005 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0782 | 0.2016 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0068 | 0.1446 | 0.2188 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0006 | 0.0005 |
Schistosoma mansoni | tyrosine kinase | 0.01 | 0.2236 | 0.2231 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0015 | 0.0115 | 0.0155 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0045 | 0.0861 | 0.1196 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0086 | 0.1893 | 0.1888 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.1274 | 0.1269 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0045 | 0.0861 | 0.1196 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0006 | 0.0005 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0011 | 0.0019 | 0.0033 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0412 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0006 | 0.0009 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0061 | 0.1274 | 0.3795 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0059 | 0.1219 | 0.1843 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0782 | 0.2016 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.002 | 0.0247 | 0.0244 |
Loa Loa (eye worm) | acetyltransferase | 0.0146 | 0.3384 | 0.5124 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0011 | 0.0019 | 0.0006 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0861 | 0.1196 |
Leishmania major | cytochrome p450-like protein | 0.0011 | 0.0019 | 0.0006 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0782 | 0.2016 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0011 | 0.0019 | 0.0006 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0066 | 0.1407 | 0.3628 |
Echinococcus granulosus | caspase 3 apoptosis cysteine peptidase | 0.0118 | 0.2683 | 0.2681 |
Trypanosoma brucei | metacaspase | 0.0045 | 0.0861 | 0.2221 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.0146 | 0.0216 |
Echinococcus multilocularis | apoptotic protease activating factor 1 | 0.0041 | 0.0785 | 0.0782 |
Brugia malayi | Protein kinase domain containing protein | 0.0059 | 0.1219 | 0.1846 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0006 | 0.0009 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0041 | 0.0782 | 0.1084 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0017 | 0.0187 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0249 | 0.0373 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.002 | 0.0249 | 0.0604 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0059 | 0.1219 | 0.1216 |
Brugia malayi | Pre-SET motif family protein | 0.021 | 0.4982 | 0.7548 |
Echinococcus multilocularis | caspase | 0.0118 | 0.2683 | 0.2681 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0006 | 0.0009 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0041 | 0.0782 | 0.1159 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0045 | 0.0861 | 0.1196 |
Schistosoma mansoni | tyrosine kinase | 0.0187 | 0.4397 | 0.4393 |
Leishmania major | hypothetical protein, conserved | 0.0016 | 0.0146 | 0.0335 |
Loa Loa (eye worm) | glutaminase | 0.0275 | 0.6601 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0861 | 0.1196 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0782 | 0.2016 |
Leishmania major | DNA polymerase kappa, putative | 0.0021 | 0.0281 | 0.0686 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0013 | 0.0069 | 0.0075 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0068 | 0.1446 | 0.1444 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0061 | 0.1267 | 0.1916 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 0.1274 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0224 | 0.0294 |
Echinococcus granulosus | eukaryotic initiation factor 4A | 0.0011 | 0.0017 | 0.0014 |
Trypanosoma brucei | metacaspase MCA3 | 0.0045 | 0.0861 | 0.2221 |
Schistosoma mansoni | single-minded | 0.0049 | 0.0971 | 0.0966 |
Brugia malayi | Bloom's syndrome protein homolog | 0.002 | 0.0249 | 0.0378 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0224 | 0.0572 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0472 | 0.0711 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0031 | 0.0531 | 0.1368 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.0249 | 0.0378 |
Schistosoma mansoni | caspase-3 (C14 family) | 0.0118 | 0.2683 | 0.2679 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0011 | 0.0019 | 0.0006 |
Brugia malayi | CHE-14 protein | 0.0068 | 0.1446 | 0.2191 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0015 | 0.0115 | 0.011 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0384 | 0.0955 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0224 | 0.0539 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0168 | 0.0428 |
Brugia malayi | DnaJ domain containing protein | 0.0062 | 0.1287 | 0.195 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0015 | 0.0115 | 0.0284 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0011 | 0.0019 | 0.0033 |
Loa Loa (eye worm) | cytochrome P450 | 0.0011 | 0.0019 | 0.0024 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0785 | 0.1189 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0247 | 0.037 |
Plasmodium vivax | metacaspase 1, putative | 0.0045 | 0.0861 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0782 | 0.2009 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0043 | 0.0821 | 0.1139 |
Echinococcus multilocularis | caspase 8 | 0.0045 | 0.0861 | 0.0858 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0011 | 0.0019 | 0.0006 |
Onchocerca volvulus | 0.0013 | 0.0069 | 0.0112 | |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0015 | 0.0115 | 0.0175 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0472 | 0.0467 |
Trichomonas vaginalis | set domain proteins, putative | 0.0239 | 0.5703 | 0.8056 |
Echinococcus multilocularis | 0.0058 | 0.1198 | 0.1196 | |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0513 | 0.0511 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0384 | 0.4425 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0782 | 0.2016 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.1274 | 0.1907 |
Echinococcus multilocularis | dna polymerase eta | 0.0015 | 0.0115 | 0.0113 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0011 | 0.0019 | 0.0006 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0016 | 0.0146 | 0.037 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0165 | 0.3866 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0384 | 0.2984 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0127 | 0.2907 | 0.2905 |
Leishmania major | protein kinase, putative | 0.0013 | 0.0069 | 0.0137 |
Schistosoma mansoni | thyroid hormone receptor | 0.0137 | 0.316 | 0.3156 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0049 | 0.0975 | 0.1473 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0061 | 0.1274 | 0.1271 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.1446 | 0.2188 |
Brugia malayi | PAS domain containing protein | 0.0049 | 0.0971 | 0.1472 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0782 | 0.2016 |
Plasmodium vivax | hypothetical protein, conserved | 0.0045 | 0.0861 | 1 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0017 | 0.0187 | 0.0184 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0006 | 0.0003 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0006 | 0.0009 |
Loa Loa (eye worm) | glutaminase 2 | 0.0275 | 0.6601 | 1 |
Trypanosoma cruzi | metacaspase, putative | 0.0045 | 0.0861 | 0.2215 |
Schistosoma mansoni | tyrosine kinase | 0.01 | 0.2236 | 0.2231 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0054 | 0.1093 | 0.1652 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0013 | 0.0069 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0785 | 0.1185 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0013 | 0.0069 | 0.0165 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0281 | 0.0719 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0016 | 0.0146 | 0.0143 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0247 | 0.0241 |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.0013 | 0.0069 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0531 | 0.0801 |
Schistosoma mansoni | polycystin 1-related | 0.002 | 0.0247 | 0.0241 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0021 | 0.0281 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0006 | 0.0005 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0146 | 0.3384 | 0.3382 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0785 | 0.078 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0384 | 0.0578 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0013 | 0.0069 | 0.0075 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0165 | 0.3866 | 1 |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.0013 | 0.0069 | 0.0067 |
Schistosoma mansoni | lipoxygenase | 0.0056 | 0.1136 | 0.1131 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0294 | 0.7075 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0061 | 0.1274 | 0.3266 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0011 | 0.0019 | 0.0006 |
Schistosoma mansoni | hypothetical protein | 0.0127 | 0.2907 | 0.2903 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0056 | 0.1136 | 0.1133 |
Brugia malayi | eukaryotic initiation factor 4A | 0.0011 | 0.0017 | 0.0025 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0066 | 0.1407 | 0.1404 |
Brugia malayi | Cytochrome P450 family protein | 0.002 | 0.0238 | 0.0361 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0068 | 0.1446 | 0.1444 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0062 | 0.1287 | 0.1284 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0384 | 0.0582 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.002 | 0.0249 | 0.0373 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0045 | 0.0861 | 0.6743 |
Mycobacterium ulcerans | glutaminase | 0.0275 | 0.6601 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0069 | 0.0101 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.0146 | 0.0221 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.002 | 0.0249 | 0.0246 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0224 | 0.0312 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0006 | 0.0005 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0011 | 0.0019 | 0.0006 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0011 | 0.0019 | 0.0006 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0472 | 0.0715 |
Schistosoma mansoni | tyrosine kinase | 0.01 | 0.2236 | 0.2231 |
Echinococcus granulosus | caspase 3 | 0.0073 | 0.1575 | 0.1572 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0021 | 0.0281 | 0.0797 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0224 | 0.0309 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0168 | 0.0428 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0066 | 0.1407 | 0.3628 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0011 | 0.0017 | 0.0028 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0011 | 0.0019 | 0.0006 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.0013 | 0.0069 | 0.0101 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.1274 | 0.1907 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0011 | 0.0019 | 0.0041 |
Brugia malayi | Cytochrome P450 family protein | 0.002 | 0.0238 | 0.0361 |
Leishmania major | cytochrome p450-like protein | 0.0011 | 0.0019 | 0.0006 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.0165 | 0.3866 | 0.3865 |
Echinococcus granulosus | insulin receptor | 0.0059 | 0.1219 | 0.1216 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0013 | 0.0069 | 0.0165 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0045 | 0.0861 | 0.1196 |
Brugia malayi | jmjC domain containing protein | 0.0061 | 0.1267 | 0.192 |
Echinococcus granulosus | caspase 8 | 0.0045 | 0.0861 | 0.0858 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0016 | 0.0146 | 0.0362 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.002 | 0.0238 | 0.0357 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0224 | 0.0294 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0006 | 0.0003 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.002 | 0.0247 | 0.0244 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0006 | 0.0003 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0224 | 0.0309 |
Brugia malayi | polk-prov protein | 0.0031 | 0.0531 | 0.0805 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0006 | 0.0005 |
Brugia malayi | Cytochrome P450 family protein | 0.0049 | 0.0975 | 0.1477 |
Brugia malayi | cytochrome P450 | 0.0011 | 0.0019 | 0.0028 |
Onchocerca volvulus | 0.0031 | 0.0516 | 0.0896 | |
Plasmodium vivax | JmjC domain containing protein | 0.0016 | 0.0146 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0516 | 0.0778 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0146 | 0.0216 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0516 | 0.0782 |
Echinococcus granulosus | dna polymerase eta | 0.0015 | 0.0115 | 0.0113 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1893 | 0.2865 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0062 | 0.1287 | 0.1949 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0061 | 0.1267 | 0.1262 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0015 | 0.0115 | 0.017 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0006 | 0.0009 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0015 | 0.0115 | 0.0175 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0016 | 0.0146 | 0.0362 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0006 | 0.0003 |
Echinococcus granulosus | RUN | 0.002 | 0.0247 | 0.0244 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0006 | 0.0005 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0782 | 0.2016 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0016 | 0.0146 | 0.1529 |
Schistosoma mansoni | tyrosine kinase | 0.01 | 0.2236 | 0.2231 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0016 | 0.0146 | 0.0143 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 0.1274 | 0.1271 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0045 | 0.0861 | 0.6743 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0069 | 0.0075 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0043 | 0.0821 | 0.9528 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0015 | 0.0115 | 0.0113 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0062 | 0.1287 | 0.1282 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0011 | 0.0019 | 0.0006 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0039 | 0.0732 | 0.8468 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0224 | 0.0294 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0224 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0146 | 0.0216 |
Echinococcus granulosus | epidermal growth factor receptor | 0.01 | 0.2236 | 0.2233 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.1274 | 0.1907 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0069 | 0.0075 |
Trichomonas vaginalis | glutaminase, putative | 0.0275 | 0.6601 | 0.9329 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0011 | 0.0036 | 0.0033 |
Onchocerca volvulus | 0.002 | 0.0247 | 0.0423 | |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0294 | 0.7075 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0011 | 0.0019 | 0.0006 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0294 | 0.7075 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.0146 | 0.0216 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0294 | 0.7075 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0137 | 0.316 | 0.3158 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0006 | 0.0009 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0062 | 0.1287 | 0.3299 |
Brugia malayi | hypothetical protein | 0.0164 | 0.3841 | 0.5819 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0013 | 0.0069 | 0.0067 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0011 | 0.0017 | 0.0028 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0013 | 0.0069 | 0.0075 |
Brugia malayi | Cell death protein 3 precursor | 0.0086 | 0.1893 | 0.2868 |
Brugia malayi | hypoxia-induced factor 1 | 0.0152 | 0.3525 | 0.534 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0019 | 0.0013 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0782 | 0.2016 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0041 | 0.0782 | 0.1084 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0516 | 0.0511 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0294 | 0.7075 | 1 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0224 | 0.0339 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.002 | 0.0249 | 0.033 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0006 | 0.0005 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0187 | 0.4397 | 0.4395 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0144 | 0.333 | 1 |
Echinococcus granulosus | single minded 2 | 0.0036 | 0.0655 | 0.0652 |
Echinococcus granulosus | eukaryotic initiation factor 4A III | 0.0011 | 0.0017 | 0.0014 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.01 | 0.2236 | 0.2233 |
Echinococcus multilocularis | protein dispatched 1 | 0.0068 | 0.1446 | 0.1444 |
Schistosoma mansoni | rab6-interacting | 0.002 | 0.0247 | 0.0241 |
Trypanosoma cruzi | metacaspase, putative | 0.0045 | 0.0861 | 0.2215 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0038 | 0.071 | 0.0707 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.002 | 0.0249 | 0.033 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0006 | 0.0009 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0782 | 0.2009 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0516 | 0.4026 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0043 | 0.0821 | 0.1139 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.002 | 0.0249 | 0.0631 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0066 | 0.1407 | 0.1404 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.002 | 0.0249 | 0.033 |
Brugia malayi | hypothetical protein | 0.002 | 0.0247 | 0.0374 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0043 | 0.0821 | 0.6425 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0861 | 0.13 |
Echinococcus granulosus | dna polymerase kappa | 0.0041 | 0.0782 | 0.0779 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.0146 | 0.0221 |
Treponema pallidum | ATP-dependent RNA helicase | 0.0011 | 0.0017 | 0.0015 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0006 | 0.0009 |
Echinococcus multilocularis | eukaryotic initiation factor 4A | 0.0011 | 0.0017 | 0.0014 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0069 | 0.0075 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0006 | 0.0009 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0011 | 0.0019 | 0.0006 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0011 | 0.0017 | 0.0011 |
Plasmodium vivax | RNA helicase-1, putative | 0.0011 | 0.0017 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0006 | 0.0004 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0011 | 0.0019 | 0.0006 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.0146 | 0.0221 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0036 | 0.0655 | 0.0652 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0006 | 0.0005 |
Leishmania major | DNA polymerase eta, putative | 0.0015 | 0.0115 | 0.0257 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.01 | 0.2236 | 0.2233 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0016 | 0.0146 | 0.014 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0006 | 0.0009 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0013 | 0.0069 | 0.0075 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0011 | 0.0019 | 0.0006 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0146 | 0.3384 | 0.5126 |
Brugia malayi | bHLH-PAS transcription factor | 0.0036 | 0.0655 | 0.0992 |
Brugia malayi | Hydroxymethylglutaryl-coenzyme A reductase family protein | 0.0165 | 0.3866 | 0.5857 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0006 | 0.0009 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.002 | 0.0249 | 0.0246 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0031 | 0.0531 | 0.1368 |
Brugia malayi | hypothetical protein | 0.002 | 0.0247 | 0.0374 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0061 | 0.1267 | 0.1262 |
Loa Loa (eye worm) | RecQ helicase | 0.002 | 0.0249 | 0.0373 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0187 | 0.4397 | 0.4395 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0015 | 0.0115 | 0.0291 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0013 | 0.0069 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0006 | 0.0004 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0066 | 0.1407 | 0.2127 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0224 | 0.5 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.002 | 0.0247 | 0.0244 |
Schistosoma mansoni | rab6-interacting | 0.002 | 0.0247 | 0.0241 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0384 | 0.4354 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0041 | 0.0782 | 0.1159 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0011 | 0.0019 | 0.0006 |
Plasmodium falciparum | metacaspase 1 | 0.0045 | 0.0861 | 1 |
Schistosoma mansoni | protein phosphatase 2C | 0.0016 | 0.0146 | 0.014 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0066 | 0.1407 | 0.2131 |
Brugia malayi | hypothetical protein | 0.0016 | 0.016 | 0.0243 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0006 | 0.0003 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0516 | 0.0511 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0144 | 0.333 | 1 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0039 | 0.0732 | 0.1027 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.3866 | 0.5855 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0016 | 0.0146 | 0.0143 |
Echinococcus multilocularis | 0.0011 | 0.0019 | 0.0016 | |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.002 | 0.0247 | 0.0244 |
Echinococcus multilocularis | phd:f box containing protein | 0.0016 | 0.0146 | 0.0143 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0142 | 0.3282 | 0.328 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.0249 | 0.192 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0013 | 0.0069 | 0.0165 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0068 | 0.1446 | 0.1444 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0224 | 0.2455 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0011 | 0.0036 | 0.0033 |
Mycobacterium ulcerans | putative regulatory protein | 0.0036 | 0.0655 | 0.0966 |
Leishmania major | metacaspase, putative | 0.0045 | 0.0861 | 0.2193 |
Echinococcus multilocularis | dnaJ subfamily C 6 | 0.0062 | 0.1287 | 0.1285 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0036 | 0.003 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.0146 | 0.0216 |
Echinococcus granulosus | caspase | 0.0118 | 0.2683 | 0.2681 |
Schistosoma mansoni | DNA helicase recq5 | 0.002 | 0.0249 | 0.0244 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0038 | 0.071 | 0.0707 |
Echinococcus granulosus | caspase 2 | 0.0086 | 0.1893 | 0.1891 |
Toxoplasma gondii | eukaryotic initiation factor-4A, putative | 0.0011 | 0.0017 | 0.0085 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0782 | 0.2016 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0513 | 0.0511 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.1274 | 0.1269 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0045 | 0.0861 | 0.1196 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0294 | 0.7075 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0294 | 0.7075 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0224 | 0.0335 |
Schistosoma mansoni | cytochrome P450 | 0.0011 | 0.0019 | 0.0013 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.002 | 0.0238 | 0.0357 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0043 | 0.0821 | 0.0818 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.002 | 0.0249 | 0.033 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0006 | 0.0003 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0224 | 0.0218 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0782 | 0.2009 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0224 | 0.172 |
Loa Loa (eye worm) | CYP4Cod1 | 0.002 | 0.0238 | 0.0357 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0059 | 0.1219 | 0.1216 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0062 | 0.1287 | 0.1926 |
Echinococcus multilocularis | caspase 3, apoptosis cysteine peptidase | 0.0118 | 0.2683 | 0.2681 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0516 | 0.0511 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0061 | 0.1267 | 0.1265 |
Loa Loa (eye worm) | DnaJ domain-containing protein | 0.0062 | 0.1287 | 0.1947 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0006 | 0.0009 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0224 | 0.0221 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0043 | 0.0821 | 0.6425 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0016 | 0.0146 | 0.0143 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0006 | 0.0009 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.0013 | 0.0069 | 0.0137 |
Trypanosoma brucei | unspecified product | 0.0035 | 0.0616 | 0.1588 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.1232 | 0.9672 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0016 | 0.0146 | 0.1103 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0062 | 0.1287 | 0.3834 |
Echinococcus multilocularis | insulin receptor | 0.0059 | 0.1219 | 0.1216 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0118 | 0.2683 | 0.2679 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.0165 | 0.3866 | 0.3865 |
Brugia malayi | Cytochrome P450 family protein | 0.0011 | 0.0019 | 0.0028 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0384 | 0.0987 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0013 | 0.0069 | 0.0075 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0384 | 0.4354 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0516 | 0.0511 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0168 | 0.0428 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.002 | 0.0249 | 0.0246 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0011 | 0.0019 | 0.0006 |
Trypanosoma brucei | Eukaryotic initiation factor 4A-1 | 0.0011 | 0.0017 | 0.0036 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0006 | 0.0005 |
Schistosoma mansoni | tyrosine kinase | 0.0059 | 0.1219 | 0.1214 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0006 | 0.0003 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0782 | 0.2016 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0011 | 0.0019 | 0.0006 |
Plasmodium vivax | SET domain protein, putative | 0.0031 | 0.0516 | 0.597 |
Entamoeba histolytica | DEAD/DEAH box helicase, putative | 0.0011 | 0.0017 | 0.0015 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0045 | 0.0861 | 0.2215 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0144 | 0.333 | 0.503 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0078 | 0.1683 | 0.236 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0127 | 0.2907 | 0.2905 |
Trichomonas vaginalis | adenylate cyclase, type VII, putative | 0.0013 | 0.0069 | 0.0075 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0045 | 0.0861 | 0.1196 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0224 | 0.0221 |
Trypanosoma brucei | metacaspase MCA2 | 0.0045 | 0.0861 | 0.2221 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0015 | 0.0115 | 0.011 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0187 | 0.4397 | 0.666 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 1 uM | Inhibition of solubilized, partially purified rat liver HMG-CoA reductase | ChEMBL. | 3950901 |
Relative potency (binding) | = 3.3 | Relative potency to inhibit solubilized, partially purified rat liver HMG-CoA reductase compared with that of compactin. | ChEMBL. | 3950901 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.