Detailed information for compound 683327

Basic information

Technical information
  • TDR Targets ID: 683327
  • Name: [2-[(4-methylphenyl)amino]-2-oxoethyl] 3-acet ylindolizine-1-carboxylate
  • MW: 350.368 | Formula: C20H18N2O4
  • H donors: 1 H acceptors: 3 LogP: 3.64 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccc(cc1)C)COC(=O)c1cc(n2c1cccc2)C(=O)C
  • InChi: 1S/C20H18N2O4/c1-13-6-8-15(9-7-13)21-19(24)12-26-20(25)16-11-18(14(2)23)22-10-4-3-5-17(16)22/h3-11H,12H2,1-2H3,(H,21,24)
  • InChiKey: VSIQZDFLIIOXIU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [2-[(4-methylphenyl)amino]-2-oxo-ethyl] 3-acetylindolizine-1-carboxylate
  • 3-acetyl-1-indolizinecarboxylic acid [2-[(4-methylphenyl)amino]-2-oxoethyl] ester
  • 3-acetylindolizine-1-carboxylic acid [2-keto-2-[(4-methylphenyl)amino]ethyl] ester
  • [2-[(4-methylphenyl)amino]-2-oxo-ethyl] 3-ethanoylindolizine-1-carboxylate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0181 0.175
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0015 0.0008 0.0008
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0015 0.0008 0.0016
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0088 0.0492 0.0492
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0374 0.2392 0.4009
Loa Loa (eye worm) hypothetical protein 0.0143 0.0854 0.0854
Leishmania major hypothetical protein, conserved 0.0053 0.0256 0.2187
Trichomonas vaginalis glutamate synthase, putative 0.0015 0.0008 0.0016
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0143 0.0295
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0143 0.0295
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0374 0.2392 0.8958
Plasmodium falciparum glutathione reductase 0.0164 0.0997 1
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0148 0.1418
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0026 0.0082 0.0082
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0057 0.0285 1
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.001 0.0016
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0143 0.1188
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0148 0.5057
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0015 0.0008 0.0008
Brugia malayi Carboxylesterase family protein 0.0257 0.1613 0.1613
Loa Loa (eye worm) hypothetical protein 0.0257 0.1613 0.1613
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0015 0.0008 0.0122
Echinococcus multilocularis aryl hydrocarbon receptor 0.0026 0.0082 0.0082
Brugia malayi RNA binding protein 0.0063 0.0325 0.0325
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0015 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0094 0.0532 0.0532
Trichomonas vaginalis glutaminase, putative 0.0302 0.1912 0.3957
Entamoeba histolytica thioredoxin reductase, putative 0.0015 0.0008 0.0122
Schistosoma mansoni transcription factor LCR-F1 0.011 0.0638 0.0638
Echinococcus multilocularis thioredoxin glutathione reductase 0.0166 0.1007 0.1007
Mycobacterium tuberculosis Probable lipase LipD 0.0143 0.0854 0.1423
Schistosoma mansoni ferritin 0.0017 0.0018 0.0018
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0143 0.0854 0.4444
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0001 0.0001
Echinococcus multilocularis neuropeptide receptor A26 0.0925 0.6046 0.6046
Loa Loa (eye worm) hypothetical protein 0.1521 1 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0094 0.0532 0.0532
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0143 0.0143
Mycobacterium ulcerans bacterioferritin BfrA 0.0017 0.0018 0.0053
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0015 0.0008 0.0008
Schistosoma mansoni aldehyde dehydrogenase 0.0186 0.1143 0.1143
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0082 0.0169
Onchocerca volvulus 0.0143 0.0854 0.1767
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0325 0.0325
Schistosoma mansoni neuroligin 3 (S09 family) 0.0257 0.1613 0.1613
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0026 0.0082 0.0169
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0374 0.2392 0.4009
Echinococcus granulosus neuropeptide receptor A26 0.0925 0.6046 0.6046
Mycobacterium tuberculosis Probable lipase LipE 0.0143 0.0854 0.1423
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0143 0.2234
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0256 0.2511
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0257 0.1613 0.2699
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0325 0.0325
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0026 0.0082 0.0082
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.0377 0.0377
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0148 0.0306
Schistosoma mansoni alpha glucosidase 0.0035 0.0143 0.0143
Schistosoma mansoni hypothetical protein 0.0015 0.0008 0.0008
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0302 0.0302
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0057 0.0285 0.2442
Toxoplasma gondii aldehyde dehydrogenase 0.0186 0.1143 1
Trichomonas vaginalis mercuric reductase, putative 0.0057 0.0285 0.059
Leishmania major cytochrome p450-like protein 0.002 0.004 0.0286
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0257 0.1613 0.1613
Loa Loa (eye worm) thioredoxin reductase 0.0164 0.0997 0.0997
Brugia malayi Pre-SET motif family protein 0.0094 0.0532 0.0532
Brugia malayi follicle stimulating hormone receptor 0.023 0.1437 0.1437
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0088 0.0492 0.0492
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0324 0.2058 0.2058
Loa Loa (eye worm) hypothetical protein 0.0143 0.0854 0.0854
Trypanosoma brucei trypanothione reductase 0.0164 0.0997 1
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0015 0.0008 0.0008
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0015 0.0008 0.0122
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0057 0.0285 0.1456
Onchocerca volvulus 0.0257 0.1613 0.3338
Schistosoma mansoni ferritin light chain 0.0017 0.0018 0.0018
Trichomonas vaginalis guanylate cyclase, putative 0.0026 0.0082 0.0169
Echinococcus granulosus acetylcholinesterase 0.1521 1 1
Schistosoma mansoni acetylcholinesterase 0.0257 0.1613 0.1613
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0143 0.0295
Onchocerca volvulus 0.0026 0.0082 0.0169
Schistosoma mansoni ferritin 0.0017 0.0018 0.0018
Trypanosoma cruzi trypanothione reductase, putative 0.0057 0.0285 0.2803
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0713 0.0713
Giardia lamblia NADH oxidase lateral transfer candidate 0.0057 0.0285 1
Brugia malayi PAS domain containing protein 0.0101 0.0577 0.0577
Treponema pallidum bacterioferrin (TpF1) 0.0017 0.0018 0.0365
Echinococcus granulosus lamin dm0 0.0026 0.0082 0.0082
Schistosoma mansoni hypothetical protein 0.0088 0.0492 0.0492
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0015 0.0008 0.0008
Schistosoma mansoni lamin 0.0026 0.0082 0.0082
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0256 0.2511
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0143 0.0295
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0082 0.0169
Schistosoma mansoni sulfide quinone reductase 0.0015 0.0008 0.0008
Brugia malayi hypothetical protein 0.0257 0.1613 0.1613
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0026 0.0082 0.2662
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0057 0.0285 0.2442
Echinococcus multilocularis geminin 0.0823 0.5366 0.5366
Plasmodium vivax glutathione reductase, putative 0.0164 0.0997 1
Echinococcus multilocularis phd:f box containing protein 0.0015 0.001 0.001
Entamoeba histolytica hypothetical protein 0.011 0.0638 1
Echinococcus granulosus carboxylesterase 5A 0.1521 1 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0532 0.0532
Onchocerca volvulus 0.0257 0.1613 0.3338
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.001
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0015 0.0008 0.0008
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0143 0.1188
Loa Loa (eye worm) programmed cell death 8 0.0015 0.0008 0.0008
Schistosoma mansoni intermediate filament proteins 0.0026 0.0082 0.0082
Schistosoma mansoni sulfide quinone reductase 0.0015 0.0008 0.0008
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0064 0.0064
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.004 0.004
Echinococcus multilocularis neuropeptide s receptor 0.0925 0.6046 0.6046
Brugia malayi hypothetical protein 0.0034 0.0133 0.0133
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0143 0.2234
Loa Loa (eye worm) hypothetical protein 0.0257 0.1613 0.1613
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0324 0.2058 0.2058
Mycobacterium tuberculosis Carboxylesterase LipT 0.0257 0.1613 0.2699
Echinococcus multilocularis musashi 0.0026 0.0082 0.0082
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0325 0.0325
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0148 0.0148
Brugia malayi Thioredoxin reductase 0.0164 0.0997 0.0997
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0186 0.1143 0.1909
Schistosoma mansoni hypothetical protein 0.0452 0.2907 0.2907
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0015 0.0008 0.0016
Loa Loa (eye worm) CYP4Cod1 0.002 0.004 0.004
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0057 0.0285 0.0285
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0148 0.0148
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0325 0.0325
Toxoplasma gondii thioredoxin reductase 0.0164 0.0997 0.8711
Schistosoma mansoni aryl hydrocarbon receptor 0.0101 0.0577 0.0577
Echinococcus multilocularis carboxylesterase 5A 0.1521 1 1
Echinococcus granulosus aryl hydrocarbon receptor 0.0026 0.0082 0.0082
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0325 0.0325
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0181 0.0181
Brugia malayi Cytochrome P450 family protein 0.005 0.0241 0.0241
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.014 0.0837 0.0837
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0057 0.0285 0.2803
Onchocerca volvulus 0.0143 0.0854 0.1767
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0057 0.0285 0.1456
Echinococcus granulosus tar DNA binding protein 0.0063 0.0325 0.0325
Echinococcus granulosus thioredoxin glutathione reductase 0.0166 0.1007 0.1007
Schistosoma mansoni protein phosphatase 2C 0.0015 0.001 0.001
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0416 0.2669 1
Trichomonas vaginalis D-aminoacylase, putative 0.0143 0.0854 0.1767
Schistosoma mansoni hypothetical protein 0.0088 0.0492 0.0492
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0057 0.0285 0.2803
Loa Loa (eye worm) hypothetical protein 0.0143 0.0854 0.0854
Leishmania major hypothetical protein, conserved 0.0015 0.001 0.0016
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.001 0.0018
Brugia malayi Pre-SET motif family protein 0.0652 0.4235 0.4235
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0082 0.0082
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.029 0.029
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0143 0.0854 0.0854
Schistosoma mansoni cpg binding protein 0.0034 0.013 0.013
Echinococcus granulosus intermediate filament protein 0.0026 0.0082 0.0082
Brugia malayi Carboxylesterase family protein 0.0257 0.1613 0.1613
Mycobacterium ulcerans aldehyde dehydrogenase 0.0186 0.1143 0.5961
Schistosoma mansoni apoferritin-2 0.0017 0.0018 0.0018
Brugia malayi glutathione reductase 0.0164 0.0997 0.0997
Loa Loa (eye worm) hypothetical protein 0.0257 0.1613 0.1613
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0257 0.1613 0.1613
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0057 0.0285 0.2803
Loa Loa (eye worm) hypothetical protein 0.0257 0.1613 0.1613
Schistosoma mansoni apoptosis regulator bax 0.0088 0.0492 0.0492
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0082 0.0746
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0082 0.0169
Echinococcus granulosus para nitrobenzyl esterase 0.0257 0.1613 0.1613
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0015 0.0008 0.0008
Trichomonas vaginalis esterase, putative 0.0143 0.0854 0.1767
Brugia malayi jmjC domain containing protein 0.0015 0.001 0.001
Brugia malayi glutamate synthase 0.0015 0.0008 0.0008
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0148 0.0148
Mycobacterium leprae conserved hypothetical protein 0.0143 0.0854 0.318
Echinococcus multilocularis acetylcholinesterase 0.1521 1 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0057 0.0285 0.2803
Mycobacterium tuberculosis Conserved protein 0.0143 0.0854 0.1423
Schistosoma mansoni glutamate synthase 0.0015 0.0008 0.0008
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0082 0.0746
Echinococcus granulosus microtubule associated protein 2 0.1402 0.9209 0.9209
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.0811 0.0811
Loa Loa (eye worm) hypothetical protein 0.1521 1 1
Brugia malayi Carboxylesterase family protein 0.0257 0.1613 0.1613
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.011 0.0638 0.0638
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0324 0.2058 0.2058
Trichomonas vaginalis D-aminoacylase, putative 0.0143 0.0854 0.1767
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.001 0.001
Echinococcus granulosus geminin 0.0823 0.5366 0.5366
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0143 0.0854 0.0854
Echinococcus multilocularis neuroligin 0.0257 0.1613 0.1613
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0017 0.0018 0.0017
Echinococcus multilocularis acetylcholinesterase 0.1521 1 1
Brugia malayi beta-lactamase family protein 0.0143 0.0854 0.0854
Schistosoma mansoni apoferritin-2 0.0017 0.0018 0.0018
Onchocerca volvulus 0.0257 0.1613 0.3338
Brugia malayi Cytochrome P450 family protein 0.002 0.004 0.004
Plasmodium falciparum glutathione reductase 0.0057 0.0285 0.2803
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0158 0.5421
Brugia malayi Carboxylesterase family protein 0.0257 0.1613 0.1613
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0026 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0257 0.1613 0.1613
Brugia malayi beta-lactamase 0.0143 0.0854 0.0854
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0257 0.1613 0.2699
Entamoeba histolytica hypothetical protein 0.011 0.0638 1
Echinococcus granulosus BC026374 protein S09 family 0.0257 0.1613 0.1613
Entamoeba histolytica disulphide oxidoreductase, putative 0.0015 0.0008 0.0122
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0057 0.0285 0.2803
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.001 0.001
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0088 0.0492 0.0492
Leishmania major protein kinase, putative 0.0026 0.0082 0.065
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0082 0.0169
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0082 0.0169
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0532 0.0532
Echinococcus multilocularis transfer RNA-Lys 0.0075 0.0403 0.0403
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0256 0.2511
Loa Loa (eye worm) hypothetical protein 0.0257 0.1613 0.1613
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.029 0.029
Loa Loa (eye worm) carboxylesterase 0.0257 0.1613 0.1613
Mycobacterium ulcerans carboxylesterase, LipT 0.0257 0.1613 0.8429
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0057 0.0285 0.2442
Brugia malayi hypothetical protein 0.0338 0.2153 0.2153
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0118 0.0118
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0257 0.1613 0.1613
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0015 0.0008 0.0122
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0022 0.0022
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.029 0.029
Trypanosoma brucei glucosidase, putative 0.0035 0.0143 0.1363
Loa Loa (eye worm) hypothetical protein 0.0036 0.0148 0.0148
Trypanosoma cruzi trypanothione reductase, putative 0.0164 0.0997 1
Echinococcus granulosus lamin 0.0026 0.0082 0.0082
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0181 0.1524
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.009 0.0505 0.0505
Schistosoma mansoni jumonji domain containing protein 0.0058 0.029 0.029
Plasmodium falciparum thioredoxin reductase 0.0164 0.0997 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0324 0.2058 0.2058
Onchocerca volvulus 0.0094 0.0532 0.1101
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0008 0.0016
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0148 0.2318
Trichomonas vaginalis set domain proteins, putative 0.0742 0.4833 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0082 0.0082
Plasmodium vivax SET domain protein, putative 0.0094 0.0532 0.5305
Brugia malayi acetyltransferase, GNAT family protein 0.014 0.0837 0.0837
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0008 0.0016
Echinococcus multilocularis BC026374 protein (S09 family) 0.0257 0.1613 0.1613
Trichomonas vaginalis spcc417.12 protein, putative 0.0257 0.1613 0.3338
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0148 0.0148
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0854 0.8559
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0094 0.0532 0.0532
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0324 0.2058 0.2058
Mycobacterium tuberculosis Probable hydrolase 0.0143 0.0854 0.1423
Mycobacterium tuberculosis Conserved protein 0.0143 0.0854 0.1423
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0057 0.0285 0.2803
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0057 0.0285 0.1456
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.004 0.004
Loa Loa (eye worm) acetylcholinesterase 1 0.1521 1 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0094 0.0532 0.4621
Loa Loa (eye worm) carboxylesterase 0.0257 0.1613 0.1613
Leishmania major protein kinase, putative 0.0026 0.0082 0.065
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0057 0.0285 0.2803
Trichomonas vaginalis ferritin, putative 0.0017 0.0018 0.0037
Brugia malayi CXXC zinc finger family protein 0.0032 0.0118 0.0118
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0008 0.0016
Plasmodium falciparum JmjC domain-containing protein, putative 0.0015 0.001 0.0018
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0257 0.1613 0.1613
Schistosoma mansoni microtubule-associated protein tau 0.1402 0.9209 0.9209
Leishmania major hypothetical protein, conserved 0.0143 0.0854 0.7455
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0057 0.0285 0.0285
Echinococcus multilocularis glutamate synthase 0.0015 0.0008 0.0008
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0181 0.0374
Brugia malayi beta-lactamase family protein 0.0143 0.0854 0.0854
Leishmania major trypanothione reductase 0.0164 0.0997 0.8711
Brugia malayi bHLH-PAS transcription factor 0.0075 0.0403 0.0403
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0324 0.2058 0.2058
Loa Loa (eye worm) apoptosis regulator protein 0.0088 0.0492 0.0492
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0082 0.0746
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0186 0.1143 0.1143
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0148 0.0148
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0256 0.2511
Echinococcus multilocularis para nitrobenzyl esterase 0.0257 0.1613 0.1613
Onchocerca volvulus 0.0075 0.0403 0.0834
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0057 0.0285 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0143 0.0854 0.0854
Schistosoma mansoni ferritin 0.0017 0.0018 0.0018
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.0966 0.0966
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0181 0.0374
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0143 0.0143
Echinococcus granulosus single minded 2 0.0075 0.0403 0.0403
Echinococcus multilocularis lamin dm0 0.0026 0.0082 0.0082
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0057 0.0285 0.0285
Loa Loa (eye worm) glutaminase 2 0.0302 0.1912 0.1912
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0015 0.0008 0.0016
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0164 0.0997 0.1663
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1521 1 1
Loa Loa (eye worm) hypothetical protein 0.0143 0.0854 0.0854
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0374 0.2392 0.4009
Entamoeba histolytica hypothetical protein 0.011 0.0638 1
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0015 0.0008 0.0122
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0256 0.2511
Loa Loa (eye worm) hypothetical protein 0.0026 0.0079 0.0079
Onchocerca volvulus 0.0092 0.052 0.1076
Schistosoma mansoni glutaminase 0.0302 0.1912 0.1912
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0143 0.0295
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0057 0.0285 0.2803
Schistosoma mansoni glutamate synthase 0.0015 0.0008 0.0008
Plasmodium falciparum thioredoxin reductase 0.0057 0.0285 0.2803
Trichomonas vaginalis glutathione reductase, putative 0.0057 0.0285 0.059
Mycobacterium tuberculosis Probable esterase LipL 0.0143 0.0854 0.1423
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0143 0.0143
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0094 0.0532 0.0532
Schistosoma mansoni phd/f-box containing protein 0.0015 0.001 0.001
Loa Loa (eye worm) hypoxia-induced factor 1 0.0312 0.1979 0.1979
Schistosoma mansoni hypothetical protein 0.011 0.0638 0.0638
Onchocerca volvulus 0.0742 0.4833 1
Trypanosoma brucei cytochrome P450, putative 0.002 0.004 0.0328
Mycobacterium ulcerans aldehyde dehydrogenase 0.0186 0.1143 0.5961
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0143 0.0143
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0713 0.0713
Brugia malayi MH2 domain containing protein 0.0121 0.0713 0.0713
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0416 0.2669 0.4475
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0148 0.1418
Onchocerca volvulus 0.0143 0.0854 0.1767
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0015 0.0008 0.0008
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0057 0.0285 0.2442
Brugia malayi TAR-binding protein 0.0063 0.0325 0.0325
Trypanosoma cruzi cytochrome P450, putative 0.002 0.004 0.0328
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0143 0.1363
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0026 0.0082 0.0082
Mycobacterium tuberculosis Conserved protein 0.0143 0.0854 0.1423
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0158 0.2476
Echinococcus granulosus neuroligin 0.0257 0.1613 0.1613
Schistosoma mansoni disulfide oxidoreductase 0.0015 0.0008 0.0008
Onchocerca volvulus 0.0015 0.0008 0.0016
Echinococcus granulosus glutamate synthase 0.0015 0.0008 0.0008
Brugia malayi glutaminase DH11.1 0.0302 0.1912 0.1912
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.002 0.004 0.017
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0064 0.0064
Treponema pallidum NADH oxidase 0.0057 0.0285 1
Toxoplasma gondii NADPH-glutathione reductase 0.0057 0.0285 0.2442
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0324 0.2058 0.2058
Onchocerca volvulus 0.0257 0.1613 0.3338
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0257 0.1613 0.1613
Loa Loa (eye worm) hypothetical protein 0.0338 0.2153 0.2153
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0088 0.0492 0.0492
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0143 0.0295
Loa Loa (eye worm) RNA binding protein 0.0063 0.0325 0.0325
Loa Loa (eye worm) hypothetical protein 0.0088 0.0492 0.0492
Brugia malayi hypothetical protein 0.0053 0.0256 0.0256
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.014 0.0837 0.0837
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0082 0.0746
Loa Loa (eye worm) hypothetical protein 0.0143 0.0854 0.0854
Onchocerca volvulus 0.0257 0.1613 0.3338
Brugia malayi Carboxylesterase family protein 0.1521 1 1
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0015 0.0008 0.0008
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0143 0.0295
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0143 0.0854 0.0854
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0854 0.8559
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0148 0.0306
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0015 0.0008 0.0122
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0042 0.0185 0.0185
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.001 0.001
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0057 0.0285 1
Mycobacterium ulcerans hypothetical protein 0.0143 0.0854 0.4444
Brugia malayi jmjC domain containing protein 0.0058 0.029 0.029
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0148 0.0306
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0094 0.0532 0.0532
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0148 0.0148
Onchocerca volvulus 0.0026 0.0082 0.0169
Mycobacterium ulcerans putative regulatory protein 0.0075 0.0403 0.2075
Schistosoma mansoni hypothetical protein 0.0823 0.5366 0.5366
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.001 0.001
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.001 0.0016
Mycobacterium tuberculosis Probable reductase 0.0374 0.2392 0.4009
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0158 0.152
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0057 0.0285 0.2803
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0017 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.001
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0057 0.0285 0.0285
Schistosoma mansoni aldehyde dehydrogenase 0.0186 0.1143 0.1143
Echinococcus multilocularis microtubule associated protein 2 0.1402 0.9209 0.9209
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0026 0.0082 0.0169
Mycobacterium ulcerans esterase/lipase LipP 0.0143 0.0854 0.4444
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0088 0.0492 0.0492
Loa Loa (eye worm) glutaminase 0.0302 0.1912 0.1912
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.001 0.001
Echinococcus multilocularis cpg binding protein 0.0034 0.013 0.013
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0325 0.0325
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0256 0.2511
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0082 0.0746
Schistosoma mansoni alpha-glucosidase 0.0137 0.0819 0.0819
Plasmodium vivax hypothetical protein, conserved 0.0143 0.0854 0.8559
Brugia malayi jmjC domain containing protein 0.0015 0.001 0.001
Schistosoma mansoni single-minded 0.0101 0.0577 0.0577
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0094 0.0532 0.0532
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0057 0.0285 0.2803
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0001 0.0001
Brugia malayi jmjC domain containing protein 0.0015 0.001 0.001
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0966 0.0966
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0082 0.065
Trichomonas vaginalis guanylate cyclase, putative 0.0026 0.0082 0.0169
Brugia malayi jmjC domain containing protein 0.0015 0.001 0.001
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0017 0.0018 0.0365
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0911 0.5954 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.011 0.0638 0.0638
Schistosoma mansoni jumonji/arid domain-containing protein 0.0059 0.0302 0.0302
Schistosoma mansoni cpg binding protein 0.0032 0.0118 0.0118
Echinococcus granulosus neuropeptide s receptor 0.0925 0.6046 0.6046
Mycobacterium ulcerans aldehyde dehydrogenase 0.0186 0.1143 0.5961
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0966 0.0966
Mycobacterium ulcerans bacterioferritin BfrB 0.0017 0.0018 0.0053
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0015 0.0008 0.0008
Schistosoma mansoni ferritin 0.0017 0.0018 0.0018
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.001 0.001
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0256 0.2187
Echinococcus granulosus ferritin 0.0017 0.0018 0.0018
Loa Loa (eye worm) acetyltransferase 0.014 0.0837 0.0837
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0057 0.0285 0.2803
Schistosoma mansoni gliotactin 0.0257 0.1613 0.1613
Schistosoma mansoni jumonji/arid domain-containing protein 0.0059 0.0302 0.0302
Echinococcus granulosus expressed protein 0.0017 0.0018 0.0018
Echinococcus multilocularis ferritin 0.0017 0.0018 0.0018
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0143 0.0854 0.1423
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0053 0.0256 0.0256
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0057 0.0285 0.2803
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0148 0.0148
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0057 0.0285 0.2803
Echinococcus multilocularis dnaJ subfamily B 0.0452 0.2907 0.2907
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.0966 0.0966
Plasmodium vivax thioredoxin reductase, putative 0.0164 0.0997 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0374 0.2392 0.4009
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0416 0.2669 0.4475
Loa Loa (eye worm) glutathione reductase 0.0164 0.0997 0.0997
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0186 0.1143 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0352 0.3034
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0257 0.1613 0.3338
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0148 0.1235
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0057 0.0285 0.2803
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0143 0.0295
Schistosoma mansoni ferritin light chain 0.0017 0.0018 0.0018
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0017 0.0018 0.0038
Schistosoma mansoni BC026374 protein (S09 family) 0.0257 0.1613 0.1613
Trypanosoma brucei hypothetical protein, conserved 0.0143 0.0854 0.8559
Echinococcus granulosus cpg binding protein 0.0034 0.013 0.013
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.0966 0.0966
Schistosoma mansoni alpha-glucosidase 0.0137 0.0819 0.0819
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0143 0.0854 0.1423
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0143 0.0854 0.0854
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0042 0.0185 0.0185
Loa Loa (eye worm) cytochrome P450 family protein 0.005 0.0241 0.0241
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0082 0.0169
Schistosoma mansoni hypothetical protein 0.0088 0.0492 0.0492
Trichomonas vaginalis D-aminoacylase, putative 0.0143 0.0854 0.1767
Entamoeba histolytica hypothetical protein 0.011 0.0638 1
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0088 0.0492 0.0492
Schistosoma mansoni hypothetical protein 0.0024 0.0064 0.0064
Mycobacterium leprae Possible regulatory protein 0.0026 0.0082 0.0277
Brugia malayi hypothetical protein 0.011 0.0638 0.0638
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0652 0.4235 0.4235
Echinococcus granulosus beta LACTamase domain containing family member 0.0143 0.0854 0.0854
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0057 0.0285 0.2803
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0186 0.1143 0.1143
Loa Loa (eye worm) hypothetical protein 0.0257 0.1613 0.1613
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0181 0.1524
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0022 0.0022
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0057 0.0285 0.2803
Trypanosoma cruzi cytochrome P450, putative 0.002 0.004 0.0328
Trichomonas vaginalis penicillin-binding protein, putative 0.0143 0.0854 0.1767
Onchocerca volvulus 0.0026 0.0082 0.0169
Trichomonas vaginalis glutamate synthase, putative 0.0015 0.0008 0.0016
Brugia malayi jmjC domain containing protein 0.0059 0.0302 0.0302
Trichomonas vaginalis apoptosis inducing factor, putative 0.0015 0.0008 0.0016
Echinococcus multilocularis expressed protein 0.0017 0.0018 0.0018
Mycobacterium leprae Probable lipase LipE 0.0143 0.0854 0.318
Toxoplasma gondii ABC1 family protein 0.0143 0.0854 0.7455
Mycobacterium ulcerans lipase LipD 0.0143 0.0854 0.4444
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0015 0.0008 0.0008
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0082 0.0746
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0148 0.0148
Loa Loa (eye worm) follicle stimulating hormone receptor 0.023 0.1437 0.1437
Echinococcus granulosus phd:f box containing protein 0.0015 0.001 0.001
Brugia malayi Cytochrome P450 family protein 0.002 0.004 0.004
Echinococcus granulosus lysine specific demethylase 5A 0.0059 0.0302 0.0302
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.001 0.001
Trichomonas vaginalis penicillin-binding protein, putative 0.0143 0.0854 0.1767
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0374 0.2392 0.4009
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0325 0.0325
Schistosoma mansoni cpg binding protein 0.0034 0.013 0.013
Mycobacterium tuberculosis Probable oxidoreductase 0.0416 0.2669 0.4475
Loa Loa (eye worm) carboxylesterase 0.1521 1 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0008 0.0016
Echinococcus multilocularis lamin 0.0026 0.0082 0.0082
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0015 0.0008 0.0008
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.001 0.001
Brugia malayi intermediate filament protein 0.0026 0.0082 0.0082
Echinococcus granulosus dnaJ subfamily B 0.0452 0.2907 0.2907
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0057 0.0285 0.2442
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.001
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0324 0.2058 0.2058
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0324 0.2058 0.2058
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0143 0.0295
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0148 0.1418
Plasmodium vivax JmjC domain containing protein 0.0015 0.001 0.0018
Schistosoma mansoni glutamate synthase 0.0015 0.0008 0.0008
Loa Loa (eye worm) beta-lactamase 0.0143 0.0854 0.0854
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0057 0.0285 0.0466
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0143 0.1363
Mycobacterium ulcerans glutaminase 0.0302 0.1912 1
Trichomonas vaginalis adenylate cyclase, putative 0.0026 0.0082 0.0169
Echinococcus granulosus acetylcholinesterase 0.1521 1 1
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0325 0.0325
Schistosoma mansoni lamin 0.0026 0.0082 0.0082
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0008 0.0016
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0148 0.0148
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0015 0.0008 0.0008
Brugia malayi hypoxia-induced factor 1 0.0312 0.1979 0.1979
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0008 0.0016
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.001 0.0018
Schistosoma mansoni hypothetical protein 0.0823 0.5366 0.5366
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0026 0.0082 0.0082
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0015 0.0008 0.0008
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0082 0.0082
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0143 0.0854 0.1423
Schistosoma mansoni jumonji domain containing protein 0.0015 0.001 0.001
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0015 0.0008 0.0008
Mycobacterium ulcerans beta-lactamase 0.0143 0.0854 0.4444
Onchocerca volvulus 0.0032 0.0118 0.0245
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0325 0.0325
Echinococcus multilocularis beta LACTamase domain containing family member 0.0143 0.0854 0.0854

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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