Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 1 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.5371 | 0.5371 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.5929 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.5929 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.5929 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.5929 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.5929 | 0.5 |
Brugia malayi | hypothetical protein | 0.0036 | 0.5929 | 0.5929 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.5929 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.5929 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.5371 | 0.906 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.5371 | 0.5371 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.5929 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.