Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0041 | 0.3161 | 0.3289 |
Echinococcus granulosus | tar DNA binding protein | 0.0052 | 0.4413 | 0.4413 |
Echinococcus multilocularis | tar DNA binding protein | 0.0052 | 0.4413 | 0.4413 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0041 | 0.3161 | 0.3161 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0041 | 0.3161 | 0.3289 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0052 | 0.4413 | 0.4591 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 1 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0099 | 0.9612 | 0.9612 |
Schistosoma mansoni | tar DNA-binding protein | 0.0052 | 0.4413 | 0.4413 |
Schistosoma mansoni | tar DNA-binding protein | 0.0052 | 0.4413 | 0.4413 |
Echinococcus multilocularis | serotonin receptor | 0.0102 | 1 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0028 | 0.1698 | 0.1767 |
Echinococcus multilocularis | serotonin receptor | 0.0102 | 1 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0099 | 0.9612 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0052 | 0.4413 | 0.4413 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0052 | 0.4413 | 0.4413 |
Schistosoma mansoni | tar DNA-binding protein | 0.0052 | 0.4413 | 0.4413 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.1698 | 0.1698 |
Brugia malayi | RNA binding protein | 0.0052 | 0.4413 | 0.4591 |
Schistosoma mansoni | tar DNA-binding protein | 0.0052 | 0.4413 | 0.4413 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0102 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0052 | 0.4413 | 0.4413 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.1698 | 0.1698 |
Brugia malayi | TAR-binding protein | 0.0052 | 0.4413 | 0.4591 |
Loa Loa (eye worm) | RNA binding protein | 0.0052 | 0.4413 | 0.4413 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.3161 | 0.3161 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0099 | 0.9612 | 0.9612 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.