Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.2503 | 0.6502 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0049 | 0.3849 | 0.5 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.3849 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.2503 | 0.6502 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0049 | 0.3849 | 0.3849 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0049 | 0.3849 | 0.5 |
Brugia malayi | MAP kinase sur-1 | 0.0049 | 0.3849 | 0.3849 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.3849 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.2503 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0049 | 0.3849 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.2503 | 0.5 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0049 | 0.3849 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.2503 | 0.6502 |
Brugia malayi | hypothetical protein | 0.0035 | 0.2503 | 0.2503 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.2503 | 0.5 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0049 | 0.3849 | 0.5 |
Trypanosoma brucei | protein kinase, putative | 0.0049 | 0.3849 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0049 | 0.3849 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 1 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0049 | 0.3849 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0049 | 0.3849 | 0.5 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0049 | 0.3849 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.3849 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0049 | 0.3849 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0049 | 0.3849 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.2503 | 0.6502 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0049 | 0.3849 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0049 | 0.3849 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0049 | 0.3849 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.2503 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.3849 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.