Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0081 | 0.1272 | 0.1185 |
Schistosoma mansoni | zinc finger protein | 0.0015 | 0.0127 | 0.0623 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0089 | 0.1418 | 0.1332 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0031 | 0.0398 | 0.0914 |
Mycobacterium tuberculosis | Conserved protein | 0.0031 | 0.0398 | 0.0302 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0018 | 0.0169 | 0.1329 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.001 | 0.0036 | 0.0083 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.038 | 0.0873 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0168 | 0.0387 |
Plasmodium falciparum | glutathione reductase | 0.0039 | 0.0545 | 0.3798 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.0443 | 0.3482 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0158 | 0.1241 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0031 | 0.0398 | 0.1945 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0195 | 0.082 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0018 | 0.0169 | 0.1329 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0525 | 0.1207 |
Mycobacterium ulcerans | hypothetical protein | 0.0031 | 0.0398 | 0.0302 |
Onchocerca volvulus | 0.0031 | 0.0398 | 0.0044 | |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0033 | 0.0442 | 0.2159 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0687 | 0.1578 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0089 | 0.1418 | 0.1332 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.1272 | 0.1185 |
Mycobacterium tuberculosis | Conserved protein | 0.0031 | 0.0398 | 0.0302 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0089 | 0.1418 | 0.1332 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0031 | 0.0398 | 0.6709 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0169 | 0.0827 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0282 | 0.138 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0039 | 0.0545 | 0.045 |
Brugia malayi | beta-lactamase | 0.0031 | 0.0398 | 0.0914 |
Loa Loa (eye worm) | inositol-1 | 0.0034 | 0.0457 | 0.105 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.1684 | 0.3866 |
Leishmania major | hypothetical protein, conserved | 0.0015 | 0.0127 | 0.0639 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0031 | 0.0398 | 0.8346 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0687 | 0.5401 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0195 | 0.0954 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0034 | 0.0457 | 0.3053 |
Trypanosoma brucei | trypanothione reductase | 0.0039 | 0.0545 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0039 | 0.0545 | 0.125 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0089 | 0.1418 | 0.1108 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0443 | 0.2165 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0398 | 0.0914 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0031 | 0.0398 | 0.8346 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.022 | 0.0505 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0195 | 0.2159 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0034 | 0.0457 | 1 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0039 | 0.0545 | 0.3798 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0033 | 0.0442 | 0.3472 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0195 | 0.082 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0023 | 0.018 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0195 | 0.0097 |
Loa Loa (eye worm) | hypothetical protein | 0.0258 | 0.4355 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0196 | 0.3282 | 0.3215 |
Onchocerca volvulus | 0.0258 | 0.4355 | 1 | |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 0.1877 | 0.4311 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0158 | 0.0771 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0127 | 0.0623 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0031 | 0.0395 | 0.0299 |
Onchocerca volvulus | Huntingtin homolog | 0.0104 | 0.1684 | 0.3279 |
Onchocerca volvulus | 0.0031 | 0.0398 | 0.0044 | |
Toxoplasma gondii | thioredoxin reductase | 0.0039 | 0.0545 | 0.045 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0031 | 0.0398 | 0.0302 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0034 | 0.0457 | 0.8039 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0081 | 0.1272 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0031 | 0.0398 | 0.3128 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0031 | 0.0398 | 0.8346 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0195 | 0.2686 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0127 | 0.0639 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.038 | 0.0873 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.0884 | 0.0793 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0925 | 0.7273 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0039 | 0.0545 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0039 | 0.0545 | 0.125 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0485 | 0.3808 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0195 | 0.2686 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.1272 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0039 | 0.0545 | 0.3798 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0398 | 0.0914 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0099 | 0.1592 | 0.1288 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.022 | 0.1074 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0687 | 0.5401 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.1272 | 0.1185 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0081 | 0.1272 | 0.0957 |
Mycobacterium leprae | conserved hypothetical protein | 0.0031 | 0.0398 | 0.0051 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0195 | 0.082 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.063 | 0.1447 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.0323 | 0.0742 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.1684 | 0.3866 |
Trichomonas vaginalis | esterase, putative | 0.0031 | 0.0398 | 0.8346 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0398 | 0.0914 |
Brugia malayi | hypothetical protein | 0.0104 | 0.1684 | 0.3866 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0031 | 0.0398 | 0.8346 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0023 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0568 | 0.1303 |
Mycobacterium ulcerans | beta-lactamase | 0.0031 | 0.0398 | 0.0302 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0099 | 0.1592 | 0.1507 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0034 | 0.0457 | 0.3593 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0687 | 0.5401 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0081 | 0.1272 | 0.1185 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 0.1877 | 0.4311 |
Brugia malayi | Inositol-1 | 0.0034 | 0.0457 | 0.105 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.1272 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0031 | 0.0398 | 0.1945 |
Toxoplasma gondii | pantoate-beta-alanine ligase | 0.0581 | 1 | 1 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0053 | 0.0787 | 0.6183 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0031 | 0.0398 | 0.6709 |
Brugia malayi | Probable ClpP-like protease | 0.0081 | 0.1272 | 0.2921 |
Brugia malayi | hypothetical protein | 0.0258 | 0.4355 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0031 | 0.0398 | 0.0051 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0053 | 0.0787 | 0.0454 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.1272 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0687 | 0.3358 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0014 | 0.0099 | 0.0227 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0031 | 0.0398 | 0.0302 |
Entamoeba histolytica | hypothetical protein | 0.0033 | 0.0442 | 0.9411 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0031 | 0.0398 | 0.3128 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0442 | 0.1014 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0034 | 0.0457 | 0.8039 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0011 | 0.0054 | 0.0124 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0034 | 0.0457 | 0.3593 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0443 | 0.2165 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0034 | 0.0457 | 0.0362 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.0231 | 0.1816 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0034 | 0.0457 | 0.8039 |
Entamoeba histolytica | hypothetical protein | 0.0033 | 0.0442 | 0.9411 |
Leishmania major | trypanothione reductase | 0.0039 | 0.0545 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0031 | 0.0398 | 0.0914 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0231 | 0.1129 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0099 | 0.1592 | 0.1507 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.004 | 0.0554 | 0.4352 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0099 | 0.1592 | 0.1507 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0063 | 0.0961 | 0.4695 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0031 | 0.0398 | 0.0302 |
Plasmodium vivax | hypothetical protein, conserved | 0.0031 | 0.0398 | 0.2548 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0081 | 0.1272 | 1 |
Plasmodium vivax | glutathione reductase, putative | 0.0039 | 0.0545 | 0.3798 |
Onchocerca volvulus | 0.0031 | 0.0398 | 0.0044 | |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0195 | 0.082 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0527 | 0.1209 |
Mycobacterium tuberculosis | Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) | 0.0581 | 1 | 1 |
Trypanosoma brucei | ISWI complex protein | 0.0015 | 0.0127 | 0.0639 |
Entamoeba histolytica | hypothetical protein | 0.0033 | 0.0442 | 0.9411 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0028 | 0.0348 | 0.2125 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0398 | 0.0914 |
Mycobacterium tuberculosis | Conserved protein | 0.0031 | 0.0398 | 0.0302 |
Schistosoma mansoni | inositol monophosphatase | 0.0034 | 0.0457 | 0.2234 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0442 | 0.2159 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0081 | 0.1272 | 1 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.001 | 0.0036 | 0.0083 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0925 | 0.7273 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0031 | 0.0398 | 0.8346 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0053 | 0.0787 | 0.6183 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0195 | 0.1534 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0034 | 0.0457 | 0.0362 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0034 | 0.0457 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0169 | 0.0827 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.1272 | 0.2921 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0195 | 0.0097 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0028 | 0.0348 | 0.2125 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0031 | 0.0395 | 0.0048 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0195 | 0.2159 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0158 | 0.1241 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0195 | 0.0448 |
Toxoplasma gondii | hypothetical protein | 0.0028 | 0.0348 | 0.0252 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0687 | 0.1578 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.038 | 0.1859 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0398 | 0.0914 |
Brugia malayi | MH2 domain containing protein | 0.0116 | 0.1877 | 0.4311 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0014 | 0.0099 | 0.0778 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0031 | 0.0398 | 0.0914 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.1272 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0031 | 0.0398 | 0.6709 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0023 | 0.018 |
Toxoplasma gondii | ABC1 family protein | 0.0031 | 0.0398 | 0.0302 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0195 | 1 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.1272 | 1 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0028 | 0.0348 | 0.2125 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0053 | 0.0787 | 0.0695 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0031 | 0.0398 | 0.0302 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0089 | 0.1418 | 0.1332 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0014 | 0.0099 | 0.0778 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0031 | 0.0398 | 0.0302 |
Mycobacterium ulcerans | lipase LipD | 0.0031 | 0.0398 | 0.0302 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0195 | 0.2159 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0089 | 0.1418 | 0.1332 |
Loa Loa (eye worm) | beta-lactamase | 0.0031 | 0.0398 | 0.0914 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0034 | 0.0457 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0687 | 0.5401 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0053 | 0.0787 | 0.0695 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0081 | 0.1272 | 0.6218 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0031 | 0.0398 | 0.0302 |
Schistosoma mansoni | inositol monophosphatase | 0.0034 | 0.0457 | 0.2234 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0195 | 0.2159 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0031 | 0.0398 | 0.0302 |
Brugia malayi | beta-lactamase family protein | 0.0031 | 0.0398 | 0.0914 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0398 | 0.0914 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0687 | 0.3358 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0031 | 0.0398 | 0.0302 |
Onchocerca volvulus | Huntingtin homolog | 0.0104 | 0.1684 | 0.3279 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0195 | 0.0448 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0158 | 0.0771 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0031 | 0.0398 | 0.0302 |
Brugia malayi | glutathione reductase | 0.0039 | 0.0545 | 0.125 |
Mycobacterium tuberculosis | Probable reductase | 0.0089 | 0.1418 | 0.1332 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0014 | 0.0099 | 0.0484 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0282 | 0.2219 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0039 | 0.0545 | 0.125 |
Brugia malayi | Bromodomain containing protein | 0.0076 | 0.119 | 0.2732 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1087 | 0.2495 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0033 | 0.0442 | 0.3472 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0034 | 0.0457 | 0.8039 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.0443 | 0.3482 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0169 | 0.0388 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0195 | 0.0954 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0485 | 0.3808 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.004 | 0.0554 | 0.4352 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0195 | 0.0097 |
Mycobacterium ulcerans | pantoate--beta-alanine ligase | 0.0581 | 1 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0034 | 0.0457 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0031 | 0.0398 | 0.6709 |
Entamoeba histolytica | hypothetical protein | 0.0033 | 0.0442 | 0.9411 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0127 | 0.0639 |
Schistosoma mansoni | bromodomain containing protein | 0.0065 | 0.0987 | 0.4825 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0687 | 0.3358 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0282 | 0.2219 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0195 | 0.1534 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.0231 | 0.1816 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.