Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | zinc finger protein | 0.002 | 0.0345 | 0.0471 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.006 | 0.718 | 0.9789 |
Schistosoma mansoni | bromodomain containing protein | 0.0065 | 0.7959 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.7335 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.4364 | 0.4709 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0062 | 0.7513 | 0.9415 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0862 | 0.0679 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0862 | 0.1148 |
Schistosoma mansoni | jumonji domain containing protein | 0.006 | 0.718 | 0.8978 |
Echinococcus granulosus | zinc finger protein | 0.002 | 0.0345 | 0.046 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.006 | 0.718 | 0.9789 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.3619 | 0.3902 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.3194 | 0.4355 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0062 | 0.7513 | 0.9415 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0062 | 0.7513 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.3607 | 0.2673 |
Brugia malayi | jmjC domain containing protein | 0.0062 | 0.7513 | 0.715 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.3194 | 0.4252 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.9255 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.7335 | 0.9763 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.006 | 0.718 | 0.9557 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0529 | 0.0559 |
Brugia malayi | jmjC domain containing protein | 0.006 | 0.718 | 0.6769 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0529 | 0.0242 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0862 | 0.1175 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0062 | 0.7513 | 0.8116 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.4032 | 0.4348 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.