Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0274 | 0.3031 | 0.4598 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0554 | 0.6591 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0274 | 0.3031 | 0.4598 |
Entamoeba histolytica | protein kinase, putative | 0.0274 | 0.3031 | 0.3031 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0554 | 0.6591 | 1 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0554 | 0.6591 | 1 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0274 | 0.3031 | 0.2954 |
Trichomonas vaginalis | AGC family protein kinase | 0.0297 | 0.3318 | 0.0514 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0554 | 0.6591 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0526 | 0.6229 | 0.9451 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0274 | 0.3031 | 0.4598 |
Schistosoma mansoni | atypical protein kinase C | 0.0274 | 0.3031 | 0.4598 |
Trichomonas vaginalis | AGC family protein kinase | 0.0822 | 1 | 1 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0532 | 0.6305 | 0.9565 |
Entamoeba histolytica | protein kinase 2, putative | 0.0532 | 0.6305 | 0.6305 |
Echinococcus granulosus | NDR protein kinase | 0.0274 | 0.3031 | 0.4598 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0109 | 0.0165 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0274 | 0.3031 | 0.4598 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0554 | 0.6591 | 0.6591 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.0526 | 0.6229 | 0.9451 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0274 | 0.3031 | 0.4598 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0274 | 0.3031 | 0.4598 |
Trichomonas vaginalis | AGC family protein kinase | 0.0822 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0822 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0822 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0822 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0822 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0274 | 0.3031 | 0.4598 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0109 | 0.0165 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0526 | 0.6229 | 0.9451 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0822 | 1 | 0.5 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0274 | 0.3031 | 0.2954 |
Brugia malayi | Protein kinase domain containing protein | 0.0274 | 0.3031 | 0.3031 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0274 | 0.3031 | 0.4598 |
Trichomonas vaginalis | AGC family protein kinase | 0.0274 | 0.3031 | 0.0107 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0274 | 0.3031 | 0.4598 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0109 | 0.0165 |
Brugia malayi | Protein kinase domain containing protein | 0.0274 | 0.3031 | 0.3031 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0274 | 0.3031 | 0.4598 |
Echinococcus granulosus | protein kinase c iota type | 0.0274 | 0.3031 | 0.4598 |
Giardia lamblia | Kinase, AGC PKA | 0.0532 | 0.6305 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0109 | 0.0165 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.0532 | 0.6305 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0274 | 0.3031 | 0.4598 |
Echinococcus granulosus | nervana 2 | 0.0526 | 0.6229 | 0.9451 |
Echinococcus multilocularis | protein kinase c iota type | 0.0274 | 0.3031 | 0.4598 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0554 | 0.6591 | 1 |
Schistosoma mansoni | serine/threonine kinase | 0.0274 | 0.3031 | 0.4598 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0274 | 0.3031 | 0.4598 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.0109 | 0.0109 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0274 | 0.3031 | 0.4598 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0532 | 0.6305 | 0.9565 |
Loa Loa (eye worm) | hypothetical protein | 0.0274 | 0.3031 | 0.2954 |
Toxoplasma gondii | AGC kinase | 0.08 | 0.9713 | 0.5 |
Echinococcus granulosus | protein kinase C gamma type | 0.0274 | 0.3031 | 0.4598 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0526 | 0.6229 | 0.9451 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.08 | 0.9713 | 0.9713 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.0526 | 0.6229 | 0.9451 |
Trichomonas vaginalis | AGC family protein kinase | 0.0274 | 0.3031 | 0.0107 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0274 | 0.3031 | 0.4598 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0274 | 0.3031 | 0.2954 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0274 | 0.3031 | 0.4598 |
Trypanosoma cruzi | Protein kinase B | 0.0554 | 0.6591 | 1 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0274 | 0.3031 | 0.4598 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0274 | 0.3031 | 0.2954 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0274 | 0.3031 | 0.4598 |
Trichomonas vaginalis | AGC family protein kinase | 0.0822 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0109 | 0.0165 |
Entamoeba histolytica | protein kinase, putative | 0.0822 | 1 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0274 | 0.3031 | 0.4598 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0274 | 0.3031 | 0.2954 |
Brugia malayi | protein kinase C II. | 0.0274 | 0.3031 | 0.3031 |
Echinococcus multilocularis | nervana 2 | 0.0526 | 0.6229 | 0.9451 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0274 | 0.3031 | 0.4598 |
Entamoeba histolytica | protein kinase, putative | 0.08 | 0.9713 | 0.9713 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0274 | 0.3031 | 0.4598 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.08 | 0.9713 | 0.971 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.0532 | 0.6305 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0274 | 0.3031 | 0.4598 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0274 | 0.3031 | 0.4598 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0554 | 0.6591 | 0.6591 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0109 | 0.0165 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0274 | 0.3031 | 0.2954 |
Trichomonas vaginalis | AGC family protein kinase | 0.0274 | 0.3031 | 0.0107 |
Brugia malayi | Hr1 repeat family protein | 0.0274 | 0.3031 | 0.3031 |
Echinococcus granulosus | nervana 2 | 0.0526 | 0.6229 | 0.9451 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0822 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0109 | 0.0165 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0532 | 0.6305 | 0.9565 |
Trichomonas vaginalis | AGC family protein kinase | 0.0822 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.