Detailed information for compound 686792

Basic information

Technical information
  • TDR Targets ID: 686792
  • Name: 3-chloro-N-[2-dimethylamino-2-(4-fluorophenyl )ethyl]benzamide
  • MW: 320.789 | Formula: C17H18ClFN2O
  • H donors: 1 H acceptors: 1 LogP: 3.49 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(C(c1ccc(cc1)F)CNC(=O)c1cccc(c1)Cl)C
  • InChi: 1S/C17H18ClFN2O/c1-21(2)16(12-6-8-15(19)9-7-12)11-20-17(22)13-4-3-5-14(18)10-13/h3-10,16H,11H2,1-2H3,(H,20,22)
  • InChiKey: SWMWGOHOJPAEKC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis mothers against decapentaplegic 5 0.0009 0.014 0.0073
Echinococcus granulosus neuroligin 0.0021 0.0606 0.1135
Loa Loa (eye worm) MH2 domain-containing protein 0.0128 0.459 0.5975
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0008 0.0108 0.0361
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.1023 0.2085
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.092 0.2803
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0022 0.0627 0.0691
Schistosoma mansoni DNA helicase recq5 0.001 0.0178 0.007
Entamoeba histolytica thioredoxin reductase, putative 0.0008 0.0108 0.3807
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0409 0.104
Schistosoma mansoni tar DNA-binding protein 0.0064 0.2188 0.2102
Schistosoma mansoni acetylcholinesterase 0.0021 0.0606 0.0504
Plasmodium falciparum thioredoxin reductase 0.0086 0.3003 1
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0694 0.1334
Brugia malayi Carboxylesterase family protein 0.0021 0.0606 0.0664
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0195 0.7087 0.8958
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.003 0.092 0.1042
Echinococcus multilocularis smad 0.0009 0.014 0.0073
Onchocerca volvulus 0.0238 0.8687 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0009 0.014 0.0043
Brugia malayi TAR-binding protein 0.0064 0.2188 0.2772
Onchocerca volvulus 0.0021 0.0606 0.0581
Trichomonas vaginalis spcc417.12 protein, putative 0.0021 0.0606 0.0581
Echinococcus multilocularis thioredoxin glutathione reductase 0.0086 0.3022 0.6637
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0178 0.0158
Leishmania major acetoin dehydrogenase e3 component-like protein 0.003 0.092 0.2803
Echinococcus multilocularis tar DNA binding protein 0.0064 0.2188 0.4737
Brugia malayi Pre-SET motif family protein 0.0209 0.761 1
Echinococcus granulosus carboxylesterase 5A 0.0126 0.4498 1
Brugia malayi Smad1 0.0009 0.014 0.0043
Schistosoma mansoni hypothetical protein 0.0032 0.1023 0.0925
Echinococcus granulosus tar DNA binding protein 0.0064 0.2188 0.4737
Leishmania major trypanothione reductase 0.0086 0.3003 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0195 0.7087 0.8958
Schistosoma mansoni hypothetical protein 0.0032 0.1023 0.0925
Mycobacterium tuberculosis Carboxylesterase LipT 0.0021 0.0606 0.0639
Giardia lamblia NADH oxidase lateral transfer candidate 0.003 0.092 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.003 0.092 1
Trichomonas vaginalis glutathione reductase, putative 0.003 0.092 0.0946
Loa Loa (eye worm) hypothetical protein 0.0126 0.4498 0.5852
Loa Loa (eye worm) hypothetical protein 0.0021 0.0606 0.0664
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0694 0.0682
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0195 0.7087 0.8958
Giardia lamblia Sgs1 DNA helicase, putative 0.001 0.0178 0.0857
Schistosoma mansoni smad 0.0009 0.014 0.0033
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.2426 0.3089
Brugia malayi MH2 domain containing protein 0.0009 0.014 0.0043
Loa Loa (eye worm) hypothetical protein 0.0021 0.0606 0.0664
Schistosoma mansoni smad1 5 8 and 0.0009 0.014 0.0033
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0933 0.3108
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0086 0.3003 0.3716
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0009 0.014 0.0073
Onchocerca volvulus 0.0021 0.0606 0.0581
Echinococcus multilocularis acetylcholinesterase 0.0126 0.4498 1
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0008 0.0108 0.0361
Brugia malayi Carboxylesterase family protein 0.0126 0.4498 0.5852
Echinococcus multilocularis neuroligin 0.0021 0.0606 0.1135
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0285 0.0609
Echinococcus multilocularis para nitrobenzyl esterase 0.0021 0.0606 0.1135
Loa Loa (eye worm) hypothetical protein 0.0126 0.4498 0.5852
Loa Loa (eye worm) hypothetical protein 0.0021 0.0606 0.0664
Loa Loa (eye worm) hypothetical protein 0.0021 0.0606 0.0664
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0933 0.0834
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0209 0.761 1
Plasmodium falciparum glutathione reductase 0.003 0.092 0.2803
Toxoplasma gondii thioredoxin reductase 0.0086 0.3003 1
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0178 0.0093
Trichomonas vaginalis mercuric reductase, putative 0.003 0.092 0.0946
Entamoeba histolytica disulphide oxidoreductase, putative 0.0008 0.0108 0.3807
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0217 0.7898 1
Trypanosoma brucei trypanothione reductase 0.0086 0.3003 1
Mycobacterium tuberculosis Probable reductase 0.0195 0.7087 0.8958
Echinococcus granulosus Smad4 0.0009 0.014 0.0073
Brugia malayi Thioredoxin reductase 0.0086 0.3003 0.3859
Schistosoma mansoni smad1 5 8 and 0.0009 0.014 0.0033
Schistosoma mansoni tar DNA-binding protein 0.0064 0.2188 0.2102
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.092 0.2803
Brugia malayi Latrophilin receptor protein 2 0.0032 0.1023 0.122
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.003 0.092 0.2803
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.2188 0.2772
Brugia malayi glutathione reductase 0.0086 0.3003 0.3859
Toxoplasma gondii selenide, water dikinase 0.0008 0.0108 0.0361
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.003 0.092 0.2803
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.003 0.092 0.2803
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.092 0.2803
Loa Loa (eye worm) hypothetical protein 0.0021 0.0606 0.0664
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0021 0.0606 0.0504
Loa Loa (eye worm) RNA binding protein 0.0064 0.2188 0.2772
Schistosoma mansoni hypothetical protein 0.007 0.2426 0.2343
Loa Loa (eye worm) hypothetical protein 0.001 0.0178 0.0093
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.1023 0.122
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0933 0.0834
Plasmodium vivax glutathione reductase, putative 0.0086 0.3003 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0022 0.0627 0.0691
Loa Loa (eye worm) Smad1 0.0009 0.014 0.0043
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0103 0.3634 0.47
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.003 0.092 0.082
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.003 0.092 0.1082
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0021 0.0606 0.0504
Onchocerca volvulus 0.0021 0.0606 0.0581
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0933 0.0834
Schistosoma mansoni tar DNA-binding protein 0.0064 0.2188 0.2102
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.092 0.2803
Echinococcus granulosus smad 0.0009 0.014 0.0073
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0021 0.0606 0.0639
Loa Loa (eye worm) hypothetical protein 0.003 0.0933 0.11
Loa Loa (eye worm) MH2 domain-containing protein 0.0009 0.014 0.0043
Treponema pallidum NADH oxidase 0.003 0.092 1
Echinococcus multilocularis GPCR, family 2 0.0032 0.1023 0.2085
Loa Loa (eye worm) RecQ helicase 0.0024 0.0694 0.078
Schistosoma mansoni BC026374 protein (S09 family) 0.0021 0.0606 0.0504
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0285 1
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0285 0.0205
Loa Loa (eye worm) hypothetical protein 0.0021 0.0606 0.0664
Brugia malayi Carboxylesterase family protein 0.0021 0.0606 0.0664
Loa Loa (eye worm) hypothetical protein 0.0119 0.4238 0.5505
Plasmodium falciparum thioredoxin reductase 0.003 0.092 0.2803
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.003 0.092 0.2803
Onchocerca volvulus 0.003 0.0933 0.0962
Echinococcus granulosus para nitrobenzyl esterase 0.0021 0.0606 0.1135
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0285 0.0609
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0195 0.7087 0.8958
Loa Loa (eye worm) carboxylesterase 0.0021 0.0606 0.0664
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0178 0.0158
Loa Loa (eye worm) hypothetical protein 0.007 0.2426 0.3089
Echinococcus granulosus mothers against decapentaplegic 5 0.0009 0.014 0.0073
Trypanosoma cruzi trypanothione reductase, putative 0.0086 0.3003 1
Echinococcus granulosus bloom syndrome protein 0.0024 0.0694 0.1334
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0178 0.0093
Mycobacterium tuberculosis Probable oxidoreductase 0.0217 0.7898 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.1023 0.2085
Brugia malayi MH2 domain containing protein 0.0009 0.014 0.0043
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.092 0.2803
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.001 0.0178 0.024
Echinococcus granulosus acetylcholinesterase 0.0126 0.4498 1
Schistosoma mansoni neuroligin 3 (S09 family) 0.0021 0.0606 0.0504
Loa Loa (eye worm) carboxylesterase 0.0126 0.4498 0.5852
Schistosoma mansoni smad1 5 8 and 0.0009 0.014 0.0033
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0195 0.7087 0.8958
Echinococcus granulosus acetylcholinesterase 0.0126 0.4498 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.1023 0.122
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0178 0.0093
Mycobacterium ulcerans carboxylesterase, LipT 0.0021 0.0606 0.6138
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0008 0.0108 0.3807
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.003 0.092 0.2803
Schistosoma mansoni tar DNA-binding protein 0.0064 0.2188 0.2102
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0933 0.1879
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.003 0.092 0.2803
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0217 0.7898 1
Echinococcus granulosus BC026374 protein S09 family 0.0021 0.0606 0.1135
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.092 0.2803
Echinococcus granulosus GPCR family 2 0.0032 0.1023 0.2085
Onchocerca volvulus 0.0021 0.0606 0.0581
Loa Loa (eye worm) hypothetical protein 0.0021 0.0606 0.0664
Schistosoma mansoni gliotactin 0.0021 0.0606 0.0504
Schistosoma mansoni hypothetical protein 0.0032 0.1023 0.0925
Loa Loa (eye worm) glutathione reductase 0.0086 0.3003 0.3859
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0285 0.0609
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0021 0.0606 0.0581
Onchocerca volvulus 0.0021 0.0606 0.0581
Brugia malayi MH2 domain containing protein 0.0128 0.459 0.5975
Brugia malayi Carboxylesterase family protein 0.0021 0.0606 0.0664
Echinococcus multilocularis BC026374 protein (S09 family) 0.0021 0.0606 0.1135
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.092 0.2803
Schistosoma mansoni hypothetical protein 0.0032 0.1023 0.0925
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.2188 0.2772
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0933 0.1879
Brugia malayi RNA binding protein 0.0064 0.2188 0.2772
Loa Loa (eye worm) carboxylesterase 0.0021 0.0606 0.0664
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.092 0.2803
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.003 0.092 0.3063
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.092 0.2803
Brugia malayi Carboxylesterase family protein 0.0126 0.4498 0.5852
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0178 0.0158
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0008 0.0108 0.3807
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.092 0.2803
Schistosoma mansoni Smad4 0.0009 0.014 0.0033
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0178 0.0592
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.092 0.2803
Brugia malayi Calcitonin receptor-like protein seb-1 0.0103 0.3634 0.47
Brugia malayi Carboxylesterase family protein 0.0021 0.0606 0.0664
Loa Loa (eye worm) thioredoxin reductase 0.0086 0.3003 0.3859
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0195 0.7087 0.8958
Loa Loa (eye worm) transcription factor SMAD2 0.0128 0.459 0.5975
Loa Loa (eye worm) hypothetical protein 0.0103 0.3634 0.47
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0217 0.7898 1
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0009 0.014 0.0033
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.1023 0.2085
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0892 0.1785
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0933 0.0834
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0694 0.0682
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.1023 0.122
Schistosoma mansoni tar DNA-binding protein 0.0064 0.2188 0.2102
Loa Loa (eye worm) TAR-binding protein 0.0064 0.2188 0.2772
Echinococcus multilocularis Smad4 0.0009 0.014 0.0073
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0008 0.0108 0.0361
Plasmodium vivax SET domain protein, putative 0.003 0.0933 0.285
Brugia malayi hypothetical protein 0.0021 0.0606 0.0664
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0587 0.1654
Toxoplasma gondii NADPH-glutathione reductase 0.003 0.092 0.3063
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0178 0.0158
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.003 0.092 0.2803
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0021 0.0606 0.0639
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0103 0.3634 0.47
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.003 0.092 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.1023 0.2085
Brugia malayi MH1 domain containing protein 0.0009 0.014 0.0043
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0509 0.0405
Loa Loa (eye worm) acetylcholinesterase 1 0.0126 0.4498 0.5852
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0008 0.0108 0.3807
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0021 0.0606 0.1135
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.003 0.092 0.1848
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0178 0.0592
Brugia malayi Pre-SET motif family protein 0.003 0.0933 0.11
Trichomonas vaginalis set domain proteins, putative 0.0238 0.8687 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.003 0.092 0.1848
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0008 0.0108 0.3807
Echinococcus granulosus thioredoxin glutathione reductase 0.0086 0.3022 0.6637
Echinococcus multilocularis acetylcholinesterase 0.0126 0.4498 1
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0008 0.0108 0.0361
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.003 0.092 1
Mycobacterium ulcerans flavoprotein disulfide reductase 0.003 0.092 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0402 0.1339
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0008 0.0108 0.0361
Plasmodium falciparum glutathione reductase 0.0086 0.3003 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.092 0.2803
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0933 0.1879
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0694 0.078
Echinococcus granulosus TGF beta signal transducer SmadC 0.0009 0.014 0.0073
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0008 0.0108 0.3807
Plasmodium vivax thioredoxin reductase, putative 0.0086 0.3003 1
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0021 0.0606 0.1135
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0021 0.0606 0.0504
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.003 0.092 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0126 0.4498 0.4438
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.092 0.2803
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.003 0.092 1
Brugia malayi MH1 domain containing protein 0.0009 0.014 0.0043
Echinococcus multilocularis carboxylesterase 5A 0.0126 0.4498 1
Schistosoma mansoni DNA helicase recq1 0.001 0.0178 0.007

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.