Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | lamin | 0.0028 | 1 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 1 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.9702 | 0.9702 |
Schistosoma mansoni | lamin | 0.0028 | 1 | 1 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.1581 | 0.1581 |
Echinococcus granulosus | lamin | 0.0028 | 1 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.1284 | 0.1284 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.2446 | 0.2446 |
Echinococcus multilocularis | lamin | 0.0028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.1284 | 0.1284 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0015 | 0.2446 | 0.2446 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.1581 | 0.1581 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.1581 | 0.1581 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 1 | 1 |
Echinococcus multilocularis | musashi | 0.0028 | 1 | 1 |
Onchocerca volvulus | 0.0028 | 1 | 1 | |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 1 | 1 |
Onchocerca volvulus | 0.0028 | 1 | 1 | |
Echinococcus granulosus | lamin dm0 | 0.0028 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.