Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0022 | 0.0139 | 0.0132 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0099 | 0.1682 | 0.1684 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0019 | 0.007 | 0.0105 |
Mycobacterium leprae | conserved hypothetical protein | 0.008 | 0.131 | 0.6632 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.131 | 0.1473 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0022 | 0.0139 | 0.0209 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.011 | 0.0164 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0045 | 0.0608 | 1 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0019 | 0.007 | 0.0105 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0022 | 0.0139 | 0.0159 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.008 | 0.131 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0075 | 0.12 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.0099 | 0.1682 | 0.1684 |
Brugia malayi | Importin beta-1 subunit | 0.0033 | 0.0353 | 0.0403 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0043 | 0.0568 | 0.434 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0513 | 0.9991 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0043 | 0.0568 | 0.434 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0022 | 0.0139 | 0.1065 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0045 | 0.0608 | 0.7416 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0075 | 0.12 | 0.9164 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.011 | 0.0837 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0.011 | 0.0837 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.0022 | 0.0139 | 0.1065 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.011 | 0.0837 |
Brugia malayi | beta-lactamase | 0.008 | 0.131 | 0.1497 |
Mycobacterium ulcerans | hypothetical protein | 0.008 | 0.131 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0022 | 0.013 | 0.0195 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0075 | 0.12 | 1 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0052 | 0.0744 | 0.1114 |
Brugia malayi | MH2 domain containing protein | 0.0019 | 0.007 | 0.008 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.013 | 0.0993 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.004 | 0.0502 | 0.0751 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0022 | 0.0139 | 0.0139 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0062 | 0.0949 | 0.142 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0143 | 0.2571 | 0.3848 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.013 | 0.0993 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0022 | 0.013 | 0.0993 |
Onchocerca volvulus | 0.0065 | 0.0997 | 0.087 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.013 | 0.0993 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0024 | 0.0036 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0746 | 0.1117 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0139 | 0.1065 |
Onchocerca volvulus | 0.0075 | 0.12 | 0.1076 | |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0.011 | 0.0837 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0024 | 0.0036 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0022 | 0.013 | 0.0149 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0139 | 0.0159 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.014 | 0.2505 | 0.3749 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.011 | 0.0125 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0056 | 0.082 | 1 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0024 | 0.018 | 0.1375 |
Echinococcus granulosus | zinc finger protein | 0.0026 | 0.0219 | 0.0328 |
Echinococcus multilocularis | dna polymerase kappa | 0.0022 | 0.013 | 0.0195 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0099 | 0.1682 | 0.1684 |
Mycobacterium tuberculosis | Conserved protein | 0.008 | 0.131 | 0.1311 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0139 | 0.0159 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0024 | 0.018 | 0.0269 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0139 | 0.1065 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0065 | 0.0997 | 0.1492 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0075 | 0.12 | 0.6011 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0727 | 0.0831 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0065 | 0.0997 | 0.7612 |
Echinococcus granulosus | smad | 0.0019 | 0.007 | 0.0105 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.013 | 0.0993 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0084 | 0.1378 | 0.2063 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0022 | 0.0139 | 0.014 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0727 | 0.0806 |
Echinococcus granulosus | snurportin 1 | 0.0348 | 0.6681 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0075 | 0.12 | 0.9164 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0053 | 0.0759 | 0.076 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0139 | 0.1065 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.0464 | 0.0694 |
Schistosoma mansoni | hypothetical protein | 0.013 | 0.2296 | 0.3437 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0022 | 0.0139 | 0.014 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0022 | 0.013 | 0.0993 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0033 | 0.0353 | 0.2693 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0024 | 0.0036 |
Mycobacterium leprae | Probable lipase LipE | 0.008 | 0.131 | 0.6632 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.12 | 0.1348 |
Trypanosoma brucei | hypothetical protein, conserved | 0.008 | 0.131 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0022 | 0.013 | 0.013 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0022 | 0.0139 | 0.1065 |
Leishmania major | hypothetical protein, conserved | 0.008 | 0.131 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.008 | 0.131 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0139 | 0.1065 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.002 | 0.011 | 0.0837 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0053 | 0.0759 | 0.076 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.013 | 0.0121 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.011 | 0.0164 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.008 | 0.131 | 0.196 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0171 | 0.3127 | 0.468 |
Leishmania major | DNA polymerase kappa, putative | 0.0022 | 0.013 | 0.0993 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0735 | 0.0814 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0022 | 0.0139 | 0.014 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0171 | 0.3127 | 0.468 |
Schistosoma mansoni | DNA polymerase eta | 0.0022 | 0.013 | 0.0195 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.016 | 0.0239 |
Brugia malayi | Cytochrome P450 family protein | 0.0024 | 0.0174 | 0.0199 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.008 | 0.131 | 0.1311 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0143 | 0.2571 | 0.3848 |
Plasmodium vivax | hypothetical protein, conserved | 0.008 | 0.131 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0451 | 0.875 | 1 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0019 | 0.007 | 0.0105 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0272 | 0.5153 | 0.5878 |
Brugia malayi | hypothetical protein | 0.0256 | 0.4835 | 0.5526 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.013 | 0.0993 |
Schistosoma mansoni | smad1 5 8 and | 0.0019 | 0.007 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0256 | 0.4835 | 0.5514 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0022 | 0.0139 | 0.1065 |
Loa Loa (eye worm) | acetyltransferase | 0.0171 | 0.3127 | 0.3556 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0075 | 0.12 | 0.1201 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.008 | 0.131 | 0.196 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0025 | 0.0203 | 0.0303 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0139 | 0.0159 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.011 | 0.1904 | 1 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0022 | 0.0139 | 0.0209 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0084 | 0.1378 | 0.2063 |
Schistosoma mansoni | bromodomain containing protein | 0.0075 | 0.1196 | 0.179 |
Schistosoma mansoni | smad | 0.0019 | 0.007 | 0.0105 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.013 | 0.0993 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0348 | 0.6681 | 0.763 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.013 | 0.0993 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0022 | 0.0139 | 0.1065 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0033 | 0.0353 | 0.2693 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0139 | 0.1065 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0022 | 0.0139 | 0.1065 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.011 | 0.1336 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0256 | 0.4835 | 0.7237 |
Plasmodium falciparum | importin beta, putative | 0.0033 | 0.0353 | 0.4299 |
Schistosoma mansoni | importin beta-1 | 0.0033 | 0.0353 | 0.0528 |
Schistosoma mansoni | ran | 0.0024 | 0.018 | 0.0269 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0052 | 0.0744 | 0.5682 |
Schistosoma mansoni | survival motor neuron protein | 0.0052 | 0.0746 | 0.1117 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.011 | 0.1904 | 0.1906 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.008 | 0.131 | 0.131 |
Giardia lamblia | DINP protein human, muc B family | 0.0022 | 0.013 | 0.2137 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.011 | 0.1904 | 0.1906 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.018 | 0.2959 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.013 | 0.0993 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0139 | 0.1065 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0464 | 0.3247 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.013 | 0.0993 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.008 | 0.131 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.008 | 0.131 | 0.131 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.008 | 0.131 | 0.131 |
Leishmania major | GTP-binding protein, putative | 0.0024 | 0.018 | 0.1375 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0099 | 0.1682 | 0.1684 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0075 | 0.12 | 0.9164 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0143 | 0.2571 | 0.3848 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.082 | 0.0913 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0139 | 0.0132 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.013 | 0.0993 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0041 | 0.0061 |
Leishmania major | trypanothione reductase | 0.0043 | 0.0568 | 0.434 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0272 | 0.5153 | 0.5878 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.131 | 0.1473 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0022 | 0.0139 | 0.014 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0019 | 0.007 | 0.0053 |
Brugia malayi | MH2 domain containing protein | 0.0019 | 0.007 | 0.008 |
Brugia malayi | beta-lactamase family protein | 0.008 | 0.131 | 0.1497 |
Echinococcus multilocularis | Smad4 | 0.0019 | 0.007 | 0.0105 |
Mycobacterium ulcerans | beta-lactamase | 0.008 | 0.131 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.008 | 0.131 | 1 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0022 | 0.0139 | 0.014 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0464 | 0.3247 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0022 | 0.0139 | 0.0132 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.004 | 0.0502 | 0.0751 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0022 | 0.0139 | 0.0273 |
Brugia malayi | MH2 domain containing protein | 0.0272 | 0.5153 | 0.5889 |
Echinococcus multilocularis | snurportin 1 | 0.0348 | 0.6681 | 1 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0022 | 0.0139 | 0.014 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0024 | 0.0036 |
Schistosoma mansoni | zinc finger protein | 0.0017 | 0.0041 | 0.0061 |
Onchocerca volvulus | 0.0169 | 0.3084 | 0.2986 | |
Brugia malayi | Thioredoxin reductase | 0.0043 | 0.0568 | 0.065 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0022 | 0.013 | 0.0187 |
Trypanosoma brucei | ISWI complex protein | 0.0017 | 0.0041 | 0.031 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0071 | 0.1116 | 0.167 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.131 | 0.1473 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0024 | 0.0176 | 0.0174 |
Brugia malayi | AMP-binding enzyme family protein | 0.0075 | 0.12 | 0.1372 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0053 | 0.0759 | 0.076 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0022 | 0.0139 | 0.1065 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0075 | 0.12 | 0.9164 |
Onchocerca volvulus | 0.008 | 0.131 | 0.1187 | |
Trypanosoma cruzi | ISWI complex protein | 0.0017 | 0.0041 | 0.031 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0402 | 0.0433 |
Echinococcus multilocularis | smad | 0.0019 | 0.007 | 0.0105 |
Plasmodium vivax | SET domain protein, putative | 0.0065 | 0.0997 | 0.7612 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0143 | 0.2571 | 0.3848 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0052 | 0.0744 | 0.0744 |
Mycobacterium tuberculosis | PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0019 | 0.0078 | 0.0078 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0143 | 0.2571 | 0.2939 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.008 | 0.131 | 0.131 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0019 | 0.008 | 0.0119 |
Leishmania major | importin beta-1 subunit, putative | 0.0026 | 0.0229 | 0.1749 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.013 | 0.0993 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0022 | 0.0139 | 0.1065 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.011 | 0.1904 | 0.1906 |
Brugia malayi | hypothetical protein | 0.0169 | 0.3084 | 0.3524 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.013 | 0.0993 |
Brugia malayi | MH1 domain containing protein | 0.0019 | 0.007 | 0.008 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0024 | 0.018 | 0.0269 |
Brugia malayi | MH1 domain containing protein | 0.0019 | 0.007 | 0.008 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0024 | 0.0174 | 0.0172 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.011 | 0.0837 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0022 | 0.0139 | 0.1065 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0099 | 0.1682 | 0.8745 |
Mycobacterium ulcerans | lipase LipD | 0.008 | 0.131 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.013 | 0.0993 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0024 | 0.0036 |
Brugia malayi | Pre-SET motif family protein | 0.0065 | 0.0997 | 0.1139 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0022 | 0.0139 | 0.1065 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0143 | 0.2571 | 0.3848 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0139 | 0.1065 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0022 | 0.0139 | 0.17 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0139 | 0.0132 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0026 | 0.0229 | 0.1749 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.128 | 0.1439 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0019 | 0.007 | 0.0105 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.008 | 0.131 | 0.1311 |
Schistosoma mansoni | Smad4 | 0.0019 | 0.007 | 0.0105 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.008 | 0.131 | 0.196 |
Trichomonas vaginalis | ran, putative | 0.0024 | 0.018 | 0.018 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0043 | 0.0568 | 0.0569 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0022 | 0.013 | 0.0993 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0033 | 0.0353 | 0.2693 |
Loa Loa (eye worm) | oxidoreductase | 0.0022 | 0.0139 | 0.0132 |
Plasmodium falciparum | thioredoxin reductase | 0.0043 | 0.0568 | 0.6927 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0022 | 0.013 | 0.0149 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0022 | 0.0139 | 0.0139 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0022 | 0.0139 | 0.1065 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0164 | 0.2979 | 0.4459 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.0022 | 0.0139 | 0.1065 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0019 | 0.008 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.082 | 0.0913 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.013 | 0.0993 |
Echinococcus multilocularis | zinc finger protein | 0.0026 | 0.0219 | 0.0328 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.011 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0056 | 0.082 | 1 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.018 | 0.0206 |
Schistosoma mansoni | thyroid hormone receptor | 0.014 | 0.2505 | 0.3749 |
Trichomonas vaginalis | importin beta-1, putative | 0.0026 | 0.0229 | 0.0229 |
Schistosoma mansoni | smad1 5 8 and | 0.0019 | 0.007 | 0.0105 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0139 | 0.1065 |
Brugia malayi | RNA, U transporter 1 | 0.0093 | 0.1559 | 0.1781 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0727 | 0.0831 |
Brugia malayi | Smad1 | 0.0019 | 0.007 | 0.008 |
Loa Loa (eye worm) | beta-lactamase | 0.008 | 0.131 | 0.1473 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.008 | 0.131 | 0.1311 |
Brugia malayi | AMP-binding enzyme family protein | 0.0075 | 0.12 | 0.1372 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0464 | 0.3247 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0065 | 0.0997 | 0.1492 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0075 | 0.12 | 0.9164 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.011 | 0.011 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0033 | 0.0353 | 0.0528 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.013 | 0.0993 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0024 | 0.018 | 0.1375 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0019 | 0.007 | 0.0053 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0256 | 0.4835 | 0.7237 |
Loa Loa (eye worm) | glutathione reductase | 0.0043 | 0.0568 | 0.0624 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0143 | 0.2571 | 0.3848 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.0464 | 0.0694 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.008 | 0.131 | 0.1473 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0024 | 0.018 | 0.1375 |
Brugia malayi | Bromodomain containing protein | 0.0088 | 0.1458 | 0.1666 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.013 | 0.0993 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0019 | 0.007 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.131 | 0.1473 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0084 | 0.1378 | 0.2063 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.011 | 0.0098 |
Leishmania major | DNA polymerase eta, putative | 0.0022 | 0.013 | 0.0993 |
Brugia malayi | beta-lactamase family protein | 0.008 | 0.131 | 0.1497 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0022 | 0.0139 | 0.1065 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.0464 | 0.0694 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0023 | 0.016 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0353 | 0.0377 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0022 | 0.013 | 0.013 |
Echinococcus multilocularis | dna polymerase eta | 0.0022 | 0.013 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.12 | 0.1348 |
Onchocerca volvulus | 0.008 | 0.131 | 0.1187 | |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0139 | 0.1065 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0143 | 0.2571 | 0.3848 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0139 | 0.1065 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0075 | 0.12 | 0.6011 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0052 | 0.0746 | 0.0853 |
Leishmania major | hypothetical protein, conserved | 0.0017 | 0.0041 | 0.031 |
Schistosoma mansoni | zinc finger protein | 0.0026 | 0.0219 | 0.0328 |
Brugia malayi | glutathione reductase | 0.0043 | 0.0568 | 0.065 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0692 | 0.0765 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0402 | 0.0601 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0043 | 0.0568 | 0.0624 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0139 | 0.1065 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0024 | 0.0036 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0026 | 0.0229 | 0.0229 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.008 | 0.131 | 0.1497 |
Schistosoma mansoni | ran | 0.0024 | 0.018 | 0.0269 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0075 | 0.12 | 0.9164 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0022 | 0.013 | 0.013 |
Trypanosoma cruzi | ISWI complex protein | 0.0017 | 0.0041 | 0.031 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0044 | 0.058 | 0.0868 |
Loa Loa (eye worm) | Smad1 | 0.0019 | 0.007 | 0.0053 |
Entamoeba histolytica | hypothetical protein | 0.0026 | 0.0229 | 0.1095 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.082 | 0.0913 |
Onchocerca volvulus | 0.008 | 0.131 | 0.1187 | |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.082 | 0.0913 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.013 | 0.2296 | 0.3437 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.018 | 0.2194 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0099 | 0.1682 | 0.1684 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0071 | 0.1116 | 0.167 |
Trichomonas vaginalis | set domain proteins, putative | 0.0514 | 1 | 1 |
Trichomonas vaginalis | esterase, putative | 0.008 | 0.131 | 0.131 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0075 | 0.12 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0043 | 0.0568 | 0.6927 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0024 | 0.0036 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0044 | 0.058 | 0.0868 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.131 | 0.1473 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0019 | 0.008 | 0.0119 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.008 | 0.131 | 0.1311 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0024 | 0.0028 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.008 | 0.131 | 0.131 |
Schistosoma mansoni | thyroid hormone receptor | 0.014 | 0.2505 | 0.3749 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.082 | 0.0913 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.12 | 0.1348 |
Mycobacterium ulcerans | hypothetical protein | 0.0075 | 0.12 | 0.9164 |
Schistosoma mansoni | smad1 5 8 and | 0.0019 | 0.007 | 0.0105 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0024 | 0.018 | 0.1375 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0056 | 0.082 | 0.6265 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0026 | 0.0229 | 0.0229 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0052 | 0.0744 | 0.0744 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0084 | 0.1378 | 0.2063 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0022 | 0.013 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.1378 | 0.1552 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.0022 | 0.0139 | 0.1065 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.002 | 0.011 | 0.1802 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.013 | 0.2296 | 0.3437 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0139 | 0.014 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0022 | 0.0139 | 0.1065 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0019 | 0.008 | 0.0119 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0022 | 0.013 | 0.0121 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.011 | 0.011 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0099 | 0.1682 | 0.1684 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0727 | 0.0806 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0043 | 0.0568 | 0.434 |
Entamoeba histolytica | Ran family GTPase | 0.0024 | 0.018 | 0.0646 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0022 | 0.0139 | 0.014 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0025 | 0.0203 | 0.0303 |
Onchocerca volvulus | 0.0052 | 0.0746 | 0.0615 | |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.008 | 0.131 | 0.196 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0056 | 0.082 | 0.6265 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0075 | 0.12 | 0.1201 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0024 | 0.0036 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0143 | 0.2571 | 0.2919 |
Toxoplasma gondii | propionate-CoA ligase | 0.0022 | 0.0139 | 0.1065 |
Brugia malayi | Bromodomain containing protein | 0.0047 | 0.0637 | 0.0729 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0053 | 0.0759 | 0.076 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.018 | 0.0179 |
Toxoplasma gondii | thioredoxin reductase | 0.0043 | 0.0568 | 0.434 |
Mycobacterium tuberculosis | Probable hydrolase | 0.008 | 0.131 | 0.1311 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.008 | 0.131 | 1 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0171 | 0.3127 | 0.3573 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.008 | 0.131 | 0.1311 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0556 | 0.061 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0022 | 0.0139 | 0.0209 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.008 | 0.131 | 0.1311 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0139 | 0.014 |
Plasmodium vivax | importin-beta 2, putative | 0.0033 | 0.0353 | 0.2693 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0024 | 0.018 | 0.1375 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0022 | 0.013 | 0.0993 |
Mycobacterium tuberculosis | Conserved protein | 0.008 | 0.131 | 0.1311 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.011 | 1 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0139 | 0.014 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0045 | 0.0608 | 0.4575 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0052 | 0.0744 | 0.5682 |
Echinococcus granulosus | dna polymerase kappa | 0.0022 | 0.013 | 0.0195 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0022 | 0.013 | 0.0195 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0022 | 0.013 | 0.0195 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0025 | 0.0203 | 0.0303 |
Schistosoma mansoni | hypothetical protein | 0.0348 | 0.6681 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0024 | 0.0036 |
Brugia malayi | Pre-SET motif family protein | 0.0451 | 0.875 | 1 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0464 | 0.053 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0075 | 0.12 | 0.9164 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.011 | 0.0837 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0075 | 0.12 | 0.9164 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.013 | 0.0993 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0139 | 0.0159 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0139 | 0.1065 |
Mycobacterium tuberculosis | Conserved protein | 0.008 | 0.131 | 0.1311 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0024 | 0.0036 |
Echinococcus granulosus | importin subunit beta 1 | 0.0033 | 0.0353 | 0.0528 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0024 | 0.0028 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.011 | 0.011 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.011 | 0.0164 |
Plasmodium vivax | glutathione reductase, putative | 0.0043 | 0.0568 | 0.434 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0402 | 0.0459 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0022 | 0.013 | 0.0993 |
Brugia malayi | PHD-finger family protein | 0.0032 | 0.0338 | 0.0386 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0464 | 0.3247 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0052 | 0.0744 | 0.5682 |
Echinococcus granulosus | dna polymerase eta | 0.0022 | 0.013 | 0.0195 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0022 | 0.0139 | 0.0159 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.011 | 0.0164 |
Echinococcus granulosus | Smad4 | 0.0019 | 0.007 | 0.0105 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0464 | 0.0694 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0075 | 0.12 | 0.9164 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0139 | 0.014 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0075 | 0.12 | 0.9164 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0022 | 0.013 | 0.013 |
Brugia malayi | AMP-binding enzyme family protein | 0.0075 | 0.12 | 0.1372 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.131 | 0.1473 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0056 | 0.082 | 0.0821 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0022 | 0.0139 | 0.1065 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0065 | 0.0997 | 0.1492 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0022 | 0.0139 | 0.1065 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.3084 | 0.3506 |
Trypanosoma brucei | unspecified product | 0.0022 | 0.013 | 0.0993 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.