Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | short chain dehydrogenase | 0.0012 | 0.0096 | 0.0104 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0174 | 0.0141 |
Brugia malayi | Cytochrome P450 family protein | 0.0011 | 0.0051 | 0.0087 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0168 | 0.4053 | 0.9131 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0183 | 0.4434 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.114 | 0.2486 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0012 | 0.0096 | 0.0058 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1023 | 0.1763 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0012 | 0.0096 | 0.0104 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.1054 | 0.128 |
Loa Loa (eye worm) | cytochrome P450 | 0.0011 | 0.0051 | 0.0082 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0033 | 0.0031 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.129 | 0.2826 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0012 | 0.0096 | 0.0104 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0012 | 0.0096 | 0.0104 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0907 | 0.0877 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0174 | 0.0171 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0016 | 0.019 | 0.0187 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0011 | 0.0051 | 0.0048 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0012 | 0.0096 | 0.0104 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0033 | 0.0031 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.129 | 0.2826 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.1341 | 0.1312 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0033 | 0.0058 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0033 | 0.0053 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.129 | 0.2826 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0012 | 0.0096 | 0.0104 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0033 | 0.0053 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0174 | 0.0141 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.005 | 0.1054 | 0.1051 |
Loa Loa (eye worm) | RNA binding protein | 0.0061 | 0.1341 | 0.2313 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0033 | 0.0031 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0174 | 0.0171 |
Echinococcus multilocularis | 0.0011 | 0.0051 | 0.0048 | |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.019 | 0.0157 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0411 | 0.0459 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0033 | 0.0058 |
Mycobacterium leprae | POSSIBLE OXIDOREDUCTASE | 0.0012 | 0.0096 | 0.0104 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0016 | 0.019 | 0.0187 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0033 | 0.0053 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.019 | 0.0329 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0033 | 0.0053 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0183 | 0.4434 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0411 | 0.0725 |
Trypanosoma brucei | protein kinase, putative | 0.005 | 0.1054 | 0.128 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0174 | 0.0296 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0016 | 0.019 | 0.0187 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0033 | 0.0031 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0012 | 0.0096 | 0.0104 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0012 | 0.0096 | 0.0104 |
Onchocerca volvulus | 0.0012 | 0.0096 | 0.0662 | |
Mycobacterium ulcerans | 20-beta-hydroxysteroid dehydrogenase FabG3 | 0.0012 | 0.0096 | 0.0104 |
Onchocerca volvulus | 0.0012 | 0.0096 | 0.0662 | |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0012 | 0.0096 | 0.0104 |
Echinococcus granulosus | geminin | 0.0334 | 0.8276 | 0.8275 |
Schistosoma mansoni | hypothetical protein | 0.0334 | 0.8276 | 0.827 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0011 | 0.0063 | 0.006 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0033 | 0.0053 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0033 | 0.0031 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0907 | 0.0905 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0012 | 0.0096 | 0.0104 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0498 | 0.0861 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0016 | 0.019 | 0.0324 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0033 | 0.0053 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.005 | 0.1054 | 0.128 |
Brugia malayi | Cytochrome P450 family protein | 0.0011 | 0.0051 | 0.0087 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0033 | 0.0058 |
Echinococcus granulosus | mitogen activated protein kinase | 0.005 | 0.1054 | 0.1051 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0033 | 0.0031 |
Mycobacterium ulcerans | oxidoreductase | 0.0012 | 0.0096 | 0.0104 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0012 | 0.0096 | 0.0161 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0012 | 0.0096 | 0.0104 |
Trypanosoma brucei | pteridine reductase 1 | 0.0012 | 0.0096 | 0.0058 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0033 | 0.0058 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0033 | 0.0031 |
Brugia malayi | hypothetical protein | 0.0231 | 0.5657 | 0.9772 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0012 | 0.0096 | 0.0058 |
Giardia lamblia | Kinase, CMGC MAPK | 0.005 | 0.1054 | 0.5 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0012 | 0.0096 | 0.0104 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0907 | 0.0877 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.019 | 0.0329 |
Schistosoma mansoni | Smad4 | 0.0016 | 0.019 | 0.0157 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0411 | 0.0459 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.129 | 0.158 |
Toxoplasma gondii | hypothetical protein | 0.0051 | 0.1089 | 0.2369 |
Toxoplasma gondii | short chain dehydrogenase family protein, putative | 0.0012 | 0.0096 | 0.0104 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0183 | 0.4434 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0907 | 0.0905 |
Brugia malayi | cytochrome P450 | 0.0011 | 0.0051 | 0.0087 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.0012 | 0.0096 | 0.0093 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0183 | 0.4434 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0174 | 0.0171 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.129 | 0.1287 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0033 | 0.0031 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0012 | 0.0096 | 0.0104 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0011 | 0.0051 | 0.0082 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0174 | 0.0141 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0061 | 0.1341 | 0.2316 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0012 | 0.0096 | 0.0104 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0012 | 0.0096 | 0.0104 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0011 | 0.0063 | 0.006 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0539 | 0.0508 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.005 | 0.1054 | 0.1051 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.063 | 0.0599 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0096 | 0.0161 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0033 | 0.0053 |
Mycobacterium tuberculosis | Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) | 0.0012 | 0.0096 | 0.0104 |
Echinococcus multilocularis | tar DNA binding protein | 0.0061 | 0.1341 | 0.1338 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.003 | 0.0535 | 0.092 |
Loa Loa (eye worm) | nuclear factor I | 0.0009 | 0.0007 | 0.0008 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.0012 | 0.0096 | 0.0093 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0016 | 0.019 | 0.0324 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0183 | 0.4434 | 1 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0033 | 0.0058 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0033 | 0.0058 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0402 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.005 | 0.1054 | 0.1024 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0012 | 0.0096 | 0.0104 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0016 | 0.019 | 0.0157 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0174 | 0.0171 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.1341 | 0.1312 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0033 | 0.0031 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.129 | 0.2826 |
Loa Loa (eye worm) | Smad1 | 0.0016 | 0.019 | 0.0324 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.005 | 0.1054 | 0.128 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase | 0.0012 | 0.0096 | 0.0058 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.005 | 0.1054 | 0.128 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0012 | 0.0096 | 0.0104 |
Leishmania major | pteridine reductase 1 | 0.0012 | 0.0096 | 0.0058 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0907 | 0.0905 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0411 | 0.0459 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0033 | 0.0031 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0174 | 0.03 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0012 | 0.0096 | 0.0058 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0539 | 0.0537 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0411 | 0.0821 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0012 | 0.0096 | 0.0104 |
Toxoplasma gondii | 3-ketoacyl-(acyl-carrier-protein) reductase | 0.0012 | 0.0096 | 0.0104 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0012 | 0.0096 | 0.0104 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0033 | 0.0031 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0012 | 0.0096 | 0.0104 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0012 | 0.0096 | 0.0104 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.0012 | 0.0096 | 0.0063 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.063 | 0.1084 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0033 | 0.0058 |
Mycobacterium leprae | 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI | 0.0012 | 0.0096 | 0.0104 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.129 | 0.126 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0007 | 0.0012 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0411 | 0.0725 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.0907 | 0.1563 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.1341 | 0.1312 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0012 | 0.0096 | 0.0104 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0007 | 0.0012 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.005 | 0.1054 | 0.1051 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0033 | 0.0031 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0012 | 0.0096 | 0.0104 |
Brugia malayi | RNA binding protein | 0.0061 | 0.1341 | 0.2316 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0011 | 0.0051 | 0.0082 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0411 | 0.0709 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0151 | 0.362 | 0.4552 |
Brugia malayi | MAP kinase sur-1 | 0.005 | 0.1054 | 0.1821 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0045 | 0.0921 | 0.1111 |
Schistosoma mansoni | cytochrome P450 | 0.0011 | 0.0051 | 0.0017 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.129 | 0.1287 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0033 | 0.0058 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0012 | 0.0096 | 0.0104 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0012 | 0.0096 | 0.0058 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0012 | 0.0096 | 0.0104 |
Echinococcus granulosus | tar DNA binding protein | 0.0061 | 0.1341 | 0.1338 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.005 | 0.1054 | 0.128 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0236 | 0.5789 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0012 | 0.0096 | 0.0104 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0012 | 0.0096 | 0.0166 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0033 | 0.0031 |
Brugia malayi | Cytochrome P450 family protein | 0.0011 | 0.0051 | 0.0087 |
Echinococcus multilocularis | geminin | 0.0334 | 0.8276 | 0.8275 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.1341 | 0.1312 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.129 | 0.2826 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0411 | 0.0459 |
Mycobacterium ulcerans | hypothetical protein | 0.0168 | 0.4053 | 0.9131 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0045 | 0.0921 | 0.1111 |
Schistosoma mansoni | hypothetical protein | 0.0334 | 0.8276 | 0.827 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0319 | 0.7892 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0011 | 0.0051 | 0.0082 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0045 | 0.0921 | 0.1111 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 0.5657 | 0.9771 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.019 | 0.0157 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.1054 | 0.128 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0033 | 0.0058 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0231 | 0.5657 | 0.5655 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0236 | 0.5789 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0033 | 0.0053 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0033 | 0.0031 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.1341 | 0.1312 |
Trichomonas vaginalis | hypothetical protein | 0.0183 | 0.4434 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0033 | 0.0053 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0051 | 0.0017 |
Onchocerca volvulus | 0.0047 | 0.0979 | 1 | |
Mycobacterium tuberculosis | Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) | 0.0012 | 0.0096 | 0.0104 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0174 | 0.03 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0033 | 0.0058 |
Onchocerca volvulus | 0.0028 | 0.0498 | 0.4916 | |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.005 | 0.1054 | 0.128 |
Leishmania major | 3-oxoacyl-ACP reductase, putative | 0.0012 | 0.0096 | 0.0058 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0183 | 0.4434 | 1 |
Brugia malayi | Smad1 | 0.0016 | 0.019 | 0.0329 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0012 | 0.0096 | 0.0104 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0151 | 0.362 | 0.4552 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0319 | 0.7892 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0319 | 0.7892 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0033 | 0.0058 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0012 | 0.0096 | 0.0166 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0012 | 0.0096 | 0.0104 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.005 | 0.1054 | 0.1817 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0063 | 0.003 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0411 | 0.0725 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0183 | 0.4434 | 1 |
Leishmania major | oxidoreductase-like protein | 0.0012 | 0.0096 | 0.0058 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0187 | 0.0324 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0033 | 0.0058 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.1023 | 0.1763 |
Brugia malayi | Cytochrome P450 family protein | 0.003 | 0.0535 | 0.0925 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0174 | 0.0141 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0033 | 0.0058 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0012 | 0.0096 | 0.0104 |
Brugia malayi | MH2 domain containing protein | 0.0236 | 0.5789 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0907 | 0.0905 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0033 | 0.0058 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0979 | 0.0949 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0033 | 0.0058 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0016 | 0.019 | 0.0187 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0174 | 0.0171 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0061 | 0.1341 | 0.2313 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.019 | 0.0329 |
Echinococcus multilocularis | Smad4 | 0.0016 | 0.019 | 0.0187 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0012 | 0.0096 | 0.0104 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0033 | 0.0058 |
Schistosoma mansoni | dihydropteridine reductase | 0.0012 | 0.0096 | 0.0063 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.019 | 0.0329 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0151 | 0.362 | 0.4552 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0012 | 0.0096 | 0.0058 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.0012 | 0.0096 | 0.0161 |
Schistosoma mansoni | smad | 0.0016 | 0.019 | 0.0157 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.1303 | 0.1274 |
Entamoeba histolytica | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0012 | 0.0096 | 0.5 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0012 | 0.0096 | 0.0104 |
Schistosoma mansoni | hypothetical protein | 0.0402 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0033 | 0.0031 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.005 | 0.1054 | 0.2289 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0979 | 0.1692 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0498 | 0.0467 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0539 | 0.0537 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0033 | 0.0053 |
Brugia malayi | TAR-binding protein | 0.0061 | 0.1341 | 0.2316 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0012 | 0.0096 | 0.0104 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.1023 | 0.1767 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.1023 | 0.1767 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0979 | 0.0949 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0033 | 0.0058 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0033 | 0.0058 |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.0183 | 0.4434 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0033 | 0.0031 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0231 | 0.5657 | 0.5655 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0033 | 0.0031 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0012 | 0.0096 | 0.0104 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0539 | 0.0508 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.063 | 0.1088 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0007 | 0.0008 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.0907 | 0.1567 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0411 | 0.0705 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0907 | 0.0877 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0033 | 0.0053 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0033 | 0.0053 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0174 | 0.0296 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0319 | 0.7892 | 1 |
Echinococcus multilocularis | smad | 0.0016 | 0.019 | 0.0187 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0055 | 0.1171 | 0.1429 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0033 | 0.0053 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0012 | 0.0096 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0033 | 0.0053 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0012 | 0.0096 | 0.0058 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0033 | 0.0058 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0174 | 0.0171 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0012 | 0.0096 | 0.0104 |
Loa Loa (eye worm) | TAR-binding protein | 0.0061 | 0.1341 | 0.2313 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0045 | 0.0921 | 0.1111 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.019 | 0.0157 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0033 | 0.0031 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0012 | 0.0096 | 0.0104 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.129 | 0.126 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0033 | 0.0053 |
Echinococcus granulosus | Smad4 | 0.0016 | 0.019 | 0.0187 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0498 | 0.0856 |
Loa Loa (eye worm) | oxidoreductase | 0.0012 | 0.0096 | 0.0161 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0033 | 0.0053 |
Echinococcus granulosus | smad | 0.0016 | 0.019 | 0.0187 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0033 | 0.0058 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.