Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | steroid hormone receptor | 0.0038 | 0.035 | 0.0456 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0021 | 0.0031 | 0.0031 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0043 | 0.0456 | 0.0594 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0038 | 0.035 | 0.0456 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0466 | 0.0608 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.035 | 0.0456 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.0043 | 0.0456 | 0.0456 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0192 | 0.3413 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0038 | 0.035 | 0.035 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0021 | 0.0031 | 0.0041 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0192 | 0.3413 | 0.3552 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0021 | 0.0031 | 0.5 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0022 | 0.0052 | 0.0068 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0021 | 0.0031 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0043 | 0.0466 | 0.1286 |
Echinococcus granulosus | neuroglian | 0.0022 | 0.0052 | 0.0052 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0038 | 0.035 | 0.0456 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0038 | 0.035 | 0.0456 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0038 | 0.035 | 0.035 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0038 | 0.035 | 0.0456 |
Echinococcus granulosus | peroxidasin | 0.0022 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0038 | 0.035 | 0.0456 |
Plasmodium falciparum | glutathione reductase | 0.0062 | 0.083 | 1 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0022 | 0.0052 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0456 | 0.0594 |
Giardia lamblia | Flap structure-specific endonuclease | 0.0025 | 0.0107 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0038 | 0.035 | 0.0456 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0062 | 0.083 | 0.083 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0021 | 0.0028 | 0.0037 |
Schistosoma mansoni | cell adhesion molecule | 0.0022 | 0.0052 | 0.0052 |
Echinococcus granulosus | tar DNA binding protein | 0.0061 | 0.0822 | 0.0822 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0021 | 0.0031 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0038 | 0.035 | 0.035 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0038 | 0.035 | 0.0364 |
Echinococcus multilocularis | basic fibroblast growth factor receptor 1 A | 0.0393 | 0.7387 | 0.7689 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0025 | 0.0107 | 0.0224 |
Echinococcus granulosus | roundabout 2 | 0.0065 | 0.09 | 0.09 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.035 | 0.0456 |
Schistosoma mansoni | coup transcription factor | 0.0038 | 0.035 | 0.035 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0038 | 0.035 | 0.0364 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.035 | 0.0456 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0062 | 0.083 | 0.0864 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0038 | 0.035 | 0.0456 |
Schistosoma mansoni | thyroid hormone receptor | 0.0038 | 0.035 | 0.035 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0052 | 0.0068 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0485 | 0.0505 |
Schistosoma mansoni | vesicular amine transporter | 0.0043 | 0.0456 | 0.0456 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0298 | 0.0298 |
Treponema pallidum | NADH oxidase | 0.0021 | 0.0031 | 0.5 |
Leishmania major | trypanothione reductase | 0.0062 | 0.083 | 0.2361 |
Leishmania major | DNA polymerase eta, putative | 0.0043 | 0.0466 | 0.1286 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0038 | 0.035 | 0.0456 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0615 | 0.0801 |
Echinococcus multilocularis | dna polymerase eta | 0.0043 | 0.0466 | 0.0485 |
Schistosoma mansoni | neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule | 0.0022 | 0.0052 | 0.0052 |
Plasmodium vivax | glutathione reductase, putative | 0.0062 | 0.083 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0038 | 0.035 | 0.0364 |
Plasmodium falciparum | flap endonuclease 1 | 0.0025 | 0.0107 | 0.095 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0506 | 0.9608 | 1 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.003 | 0.0211 | 0.2252 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0298 | 0.0298 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0038 | 0.035 | 0.0456 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0038 | 0.035 | 0.0456 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.2856 | 0.2856 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.09 | 0.1173 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0051 | 0.0615 | 0.0615 |
Echinococcus multilocularis | roundabout 2 | 0.0022 | 0.0052 | 0.0055 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0038 | 0.035 | 0.0456 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.035 | 0.0456 |
Schistosoma mansoni | roundabout | 0.0022 | 0.0052 | 0.0052 |
Echinococcus multilocularis | Immunoglobulin | 0.0043 | 0.0456 | 0.0474 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0091 | 0.0119 |
Brugia malayi | Prion-like- | 0.0022 | 0.0052 | 0.0068 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0021 | 0.0031 | 0.5 |
Plasmodium falciparum | thioredoxin reductase | 0.0062 | 0.083 | 1 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0192 | 0.3413 | 0.4448 |
Schistosoma mansoni | septate junction protein | 0.0022 | 0.0052 | 0.0052 |
Echinococcus multilocularis | Immunoglobulin | 0.0043 | 0.0456 | 0.0474 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0022 | 0.0052 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0456 | 0.0594 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.003 | 0.0211 | 0.0532 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0052 | 0.0068 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0038 | 0.035 | 0.035 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.022 | 0.396 | 0.5161 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0485 | 0.0485 |
Schistosoma mansoni | cell adhesion molecule | 0.0022 | 0.0052 | 0.0052 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0043 | 0.0456 | 0.0474 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0038 | 0.035 | 0.0364 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0298 | 0.0576 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0192 | 0.3413 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0038 | 0.035 | 0.0456 |
Schistosoma mansoni | neuroglian | 0.0022 | 0.0052 | 0.0052 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.0485 | 0.0632 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.0091 | 0.0177 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0025 | 0.0107 | 0.095 |
Echinococcus granulosus | fibroblast growth factor receptor 4 | 0.0393 | 0.7387 | 0.7387 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0052 | 0.0068 |
Echinococcus granulosus | basic fibroblast growth factor receptor 1 A | 0.0393 | 0.7387 | 0.7387 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0192 | 0.3413 | 1 |
Schistosoma mansoni | septate junction protein | 0.0022 | 0.0052 | 0.0052 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0022 | 0.0052 | 0.0052 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0022 | 0.0052 | 0.0068 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0038 | 0.035 | 0.035 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0062 | 0.083 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0038 | 0.035 | 0.035 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0485 | 0.0485 |
Echinococcus multilocularis | roundabout 2 | 0.0022 | 0.0052 | 0.0055 |
Echinococcus granulosus | Immunoglobulin | 0.0043 | 0.0456 | 0.0456 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.0485 | 0.0632 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0022 | 0.0052 | 0.0068 |
Brugia malayi | glutathione reductase | 0.0062 | 0.083 | 0.1081 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0038 | 0.035 | 0.035 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0111 | 0.181 | 0.181 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0062 | 0.083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0052 | 0.0068 |
Echinococcus granulosus | twitchin | 0.0057 | 0.0741 | 0.0741 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0025 | 0.0107 | 0.0224 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0192 | 0.3413 | 1 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0192 | 0.3413 | 0.4448 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0192 | 0.3413 | 0.3413 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0038 | 0.035 | 0.0364 |
Schistosoma mansoni | cell adhesion molecule | 0.0051 | 0.0615 | 0.0615 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0022 | 0.0052 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0456 | 0.0594 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0408 | 0.7673 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0456 | 0.0594 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0111 | 0.181 | 0.1884 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.022 | 0.396 | 0.5161 |
Toxoplasma gondii | thioredoxin reductase | 0.0062 | 0.083 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0038 | 0.035 | 0.0456 |
Brugia malayi | TAR-binding protein | 0.0061 | 0.0822 | 0.1072 |
Schistosoma mansoni | tyrosine kinase | 0.0393 | 0.7387 | 0.7387 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0022 | 0.0052 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.035 | 0.0456 |
Echinococcus multilocularis | tyrosine protein kinase otk | 0.0022 | 0.0052 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.035 | 0.0456 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0043 | 0.0456 | 0.0594 |
Echinococcus multilocularis | lachesin | 0.0022 | 0.0052 | 0.0055 |
Echinococcus granulosus | hemicentin 1 | 0.0022 | 0.0052 | 0.0052 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0038 | 0.035 | 0.0456 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0298 | 0.0576 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0298 | 0.0388 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0485 | 0.0485 |
Echinococcus granulosus | neuroglian | 0.0057 | 0.0741 | 0.0741 |
Loa Loa (eye worm) | glutathione reductase | 0.0062 | 0.083 | 0.1081 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0038 | 0.035 | 0.035 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0038 | 0.035 | 0.0364 |
Brugia malayi | Thioredoxin reductase | 0.0062 | 0.083 | 0.1081 |
Echinococcus granulosus | tyrosine protein kinase otk | 0.0022 | 0.0052 | 0.0052 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0526 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0038 | 0.035 | 0.0364 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.0025 | 0.0107 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0485 | 0.0485 |
Schistosoma mansoni | titin | 0.0022 | 0.0052 | 0.0052 |
Echinococcus multilocularis | roundabout 2 | 0.0065 | 0.09 | 0.0937 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0456 | 0.0594 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.035 | 0.0456 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0822 | 0.0822 |
Echinococcus granulosus | dna polymerase eta | 0.0043 | 0.0466 | 0.0466 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0022 | 0.0052 | 0.0068 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0091 | 0.0119 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0038 | 0.035 | 0.0456 |
Echinococcus granulosus | flap endonuclease 1 | 0.0025 | 0.0107 | 0.0107 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.0091 | 0.0749 |
Brugia malayi | Flap endonuclease-1 | 0.0025 | 0.0107 | 0.014 |
Echinococcus multilocularis | neurotracting:lsamp:neurotrimin:obcam | 0.0022 | 0.0052 | 0.0055 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0038 | 0.035 | 0.035 |
Brugia malayi | nuclear hormone receptor | 0.0038 | 0.035 | 0.0456 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0062 | 0.083 | 0.2361 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0052 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.035 | 0.0456 |
Echinococcus multilocularis | hemicentin 1 | 0.0022 | 0.0052 | 0.0055 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0061 | 0.0822 | 0.1072 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0022 | 0.0052 | 0.0052 |
Echinococcus granulosus | FTZ F1 alpha | 0.0038 | 0.035 | 0.035 |
Echinococcus granulosus | geminin | 0.0164 | 0.2856 | 0.2856 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0038 | 0.035 | 0.0934 |
Echinococcus multilocularis | contactin neuroglian septate junction protein | 0.0022 | 0.0052 | 0.0055 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0024 | 0.0091 | 0.0749 |
Echinococcus multilocularis | geminin | 0.0164 | 0.2856 | 0.2973 |
Echinococcus granulosus | defective proboscis extension response | 0.0043 | 0.0456 | 0.0456 |
Schistosoma mansoni | nephrin | 0.0022 | 0.0052 | 0.0052 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0822 | 0.0822 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0061 | 0.0822 | 0.1072 |
Brugia malayi | RNA binding protein | 0.0061 | 0.0822 | 0.1072 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0038 | 0.035 | 0.0456 |
Brugia malayi | nuclear receptor NHR-88 | 0.0038 | 0.035 | 0.0456 |
Brugia malayi | hypothetical protein | 0.0043 | 0.0456 | 0.0594 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0038 | 0.035 | 0.0934 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0025 | 0.0107 | 0.0112 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0022 | 0.0052 | 0.0068 |
Schistosoma mansoni | flap endonuclease-1 | 0.0023 | 0.0059 | 0.0059 |
Plasmodium vivax | flap endonuclease 1, putative | 0.0025 | 0.0107 | 0.095 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0192 | 0.3413 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.2856 | 0.2856 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0038 | 0.035 | 0.0364 |
Echinococcus granulosus | lachesin | 0.0022 | 0.0052 | 0.0052 |
Echinococcus multilocularis | neuroglian | 0.0022 | 0.0052 | 0.0055 |
Schistosoma mansoni | DNA polymerase eta | 0.0043 | 0.0466 | 0.0466 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0062 | 0.083 | 0.1081 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.0091 | 0.0749 |
Echinococcus multilocularis | tyrosine protein kinase transmembrane receptor | 0.0021 | 0.0028 | 0.0029 |
Schistosoma mansoni | tyrosine kinase | 0.0029 | 0.0187 | 0.0187 |
Loa Loa (eye worm) | TAR-binding protein | 0.0061 | 0.0822 | 0.1072 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0038 | 0.035 | 0.0456 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0043 | 0.0466 | 0.1286 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0298 | 0.0298 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0022 | 0.0052 | 0.0068 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0024 | 0.0091 | 0.0177 |
Echinococcus multilocularis | peroxidasin | 0.0022 | 0.0052 | 0.0055 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0024 | 0.0091 | 0.0749 |
Schistosoma mansoni | thyroid hormone receptor | 0.0038 | 0.035 | 0.035 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0022 | 0.0052 | 0.0068 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0025 | 0.0107 | 0.0224 |
Schistosoma mansoni | nephrin | 0.0057 | 0.0741 | 0.0741 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0038 | 0.035 | 0.0456 |
Brugia malayi | Peroxidasin | 0.0022 | 0.0052 | 0.0068 |
Brugia malayi | ecdysteroid receptor | 0.0038 | 0.035 | 0.0456 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0038 | 0.035 | 0.035 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.0184 | 0.3239 | 1 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0021 | 0.0031 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.0091 | 0.0177 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0038 | 0.035 | 0.0456 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0021 | 0.0031 | 0.0031 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0038 | 0.035 | 0.0934 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0052 | 0.0068 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0038 | 0.035 | 0.035 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0298 | 0.0576 |
Echinococcus multilocularis | neuroglian | 0.0057 | 0.0741 | 0.0772 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0052 | 0.0068 |
Schistosoma mansoni | cell adhesion molecule | 0.0022 | 0.0052 | 0.0052 |
Echinococcus granulosus | tyrosine protein kinase transmembrane receptor | 0.0021 | 0.0028 | 0.0028 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0022 | 0.0052 | 0.0068 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0485 | 0.0485 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0.0091 | 0.0177 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0038 | 0.035 | 0.0364 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0038 | 0.035 | 0.035 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0021 | 0.0031 | 0.0033 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0043 | 0.0466 | 0.0608 |
Echinococcus granulosus | roundabout 2 | 0.0022 | 0.0052 | 0.0052 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0022 | 0.0052 | 0.0068 |
Loa Loa (eye worm) | TK protein kinase | 0.0408 | 0.7673 | 1 |
Echinococcus multilocularis | fibroblast growth factor receptor 4 | 0.0393 | 0.7387 | 0.7689 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0022 | 0.0052 | 0.0055 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0038 | 0.035 | 0.035 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0038 | 0.035 | 0.0456 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0456 | 0.0594 |
Onchocerca volvulus | 0.0038 | 0.035 | 0.0934 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0822 | 0.0822 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0038 | 0.035 | 0.035 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0025 | 0.0107 | 0.014 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0052 | 0.0068 |
Echinococcus granulosus | contactin | 0.0022 | 0.0052 | 0.0052 |
Leishmania major | DNA polymerase eta, putative | 0.003 | 0.0211 | 0.0532 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0485 | 0.0505 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.0043 | 0.0456 | 0.0456 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0298 | 0.0576 |
Loa Loa (eye worm) | RNA binding protein | 0.0061 | 0.0822 | 0.1072 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0192 | 0.3413 | 0.3413 |
Onchocerca volvulus | 0.0162 | 0.2819 | 0.8682 | |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0298 | 0.031 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0022 | 0.0052 | 0.0068 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0038 | 0.035 | 0.035 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0038 | 0.035 | 0.035 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0038 | 0.035 | 0.0456 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0038 | 0.035 | 0.0456 |
Echinococcus granulosus | roundabout 2 | 0.0022 | 0.0052 | 0.0052 |
Echinococcus multilocularis | hemicentin 1 | 0.0022 | 0.0052 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.09 | 0.1173 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0822 | 0.0822 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0038 | 0.035 | 0.0456 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0021 | 0.0031 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0822 | 0.0822 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0038 | 0.035 | 0.0456 |
Echinococcus multilocularis | tar DNA binding protein | 0.0061 | 0.0822 | 0.0856 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0022 | 0.0052 | 0.0068 |
Trypanosoma brucei | trypanothione reductase | 0.0062 | 0.083 | 0.2361 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0021 | 0.0031 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 2 uM | Inhibition of Staphylococcus aureus 7,8-dihydroneopterin aldolase | ChEMBL. | 15027862 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.