Detailed information for compound 68889

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 298.3 | Formula: C14H14N6O2
  • H donors: 3 H acceptors: 4 LogP: 1.7 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)Nc1nc(N)c2c(n1)nc([nH]2)c1ccccc1
  • InChi: 1S/C14H14N6O2/c1-2-22-14(21)20-13-17-10(15)9-12(19-13)18-11(16-9)8-6-4-3-5-7-8/h3-7H,2H2,1H3,(H4,15,16,17,18,19,20,21)
  • InChiKey: RSOGZRIJNNMDAI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0261 0.1976 0.4167
Echinococcus granulosus rho guanine nucleotide exchange factor 7 0.0128 0.0655 0.138
Loa Loa (eye worm) hypothetical protein 0.013 0.0673 0.0673
Brugia malayi cytokine inducible SH2-containing protein 5 0.0137 0.0744 0.0744
Schistosoma mansoni protein kinase 0.0084 0.0222 0.0554
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Entamoeba histolytica BAR/SH3 domain containing protein 0.0128 0.0655 0.3989
Loa Loa (eye worm) TK/FER protein kinase 0.0203 0.1406 0.1406
Entamoeba histolytica protein kinase, putative 0.022 0.1575 1
Brugia malayi Protein kinase domain containing protein 0.0066 0.0044 0.0044
Schistosoma mansoni protein kinase 0.0186 0.1238 0.309
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.013 0.0673 0.4106
Loa Loa (eye worm) hypothetical protein 0.0157 0.094 0.094
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0137 0.0744 0.1568
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0063 0.0012 0.0014
Echinococcus granulosus c src tyrosine kinase 0.0331 0.2678 0.5646
Entamoeba histolytica protein kinase, putative 0.0067 0.0045 0.0005
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0199 0.1363 0.1363
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0126 0.064 0.064
Entamoeba histolytica hypothetical protein 0.0067 0.0049 0.0033
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0067 0.0045 0.0051
Trichomonas vaginalis AGC family protein kinase 0.0145 0.083 0.6601
Toxoplasma gondii STE kinase 0.0067 0.0045 0.0009
Schistosoma mansoni sorting nexin 0.0128 0.0655 0.1634
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0109 0.0463 0.2739
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0084 0.0222 0.0253
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0137 0.0744 0.1568
Entamoeba histolytica protein kinase domain containing protein 0.0145 0.083 0.5132
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0465 0.4007 0.4574
Schistosoma mansoni hypothetical protein 0.0137 0.0744 0.1856
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0137 0.0744 0.0744
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0092 0.0301 0.0634
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0813 0.2028
Plasmodium falciparum protein kinase, putative 0.0067 0.0045 0.0009
Leishmania major protein kinase, putative 0.0084 0.0222 0.1162
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Schistosoma mansoni protein kinase 0.0261 0.1976 0.4932
Brugia malayi Protein kinase domain containing protein 0.0155 0.0922 0.0922
Entamoeba histolytica protein kinase, putative 0.0067 0.0045 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0128 0.0655 0.513
Schistosoma mansoni suppressor of cytokine signaling 0.0137 0.0744 0.1856
Plasmodium falciparum glycogen synthase kinase 3 0.0126 0.064 0.6789
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0533 0.4688 0.4688
Loa Loa (eye worm) hypothetical protein 0.0128 0.0655 0.0655
Brugia malayi SH2 domain containing protein 0.0137 0.0744 0.0744
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0109 0.0463 0.0529
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Brugia malayi intracellular kinase 0.0126 0.064 0.064
Entamoeba histolytica protein kinase, putative 0.0067 0.0045 0.0005
Echinococcus granulosus tyrosine protein kinase Lyn 0.0483 0.4184 0.8822
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Loa Loa (eye worm) hypothetical protein 0.0115 0.0524 0.0524
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Echinococcus granulosus tyrosine protein kinase Src42A 0.0272 0.2092 0.441
Onchocerca volvulus 0.0067 0.0045 0.0045
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Loa Loa (eye worm) hypothetical protein 0.0157 0.0949 0.0949
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0109 0.0463 0.2739
Entamoeba histolytica tyrosine kinase, putative 0.0067 0.0045 0.0005
Schistosoma mansoni hypothetical protein 0.0137 0.0744 0.1856
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.028 0.217 0.217
Echinococcus granulosus protein kinase c epsilon type 0.0063 0.0008 0.0017
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Echinococcus granulosus tensin 0.0137 0.0744 0.1568
Schistosoma mansoni serine/threonine protein kinase 0.0063 0.0008 0.002
Loa Loa (eye worm) protein kinase domain-containing protein 0.0067 0.0045 0.0045
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Echinococcus multilocularis epidermal growth factor receptor 0.0133 0.0709 0.0809
Entamoeba histolytica protein kinase, putative 0.0067 0.0045 0.0005
Giardia lamblia Kinase, NEK 0.0135 0.0724 0.5715
Entamoeba histolytica protein kinase domain containing protein 0.0075 0.0126 0.0533
Echinococcus multilocularis cyclin dependent kinase 1 0.0066 0.0044 0.005
Entamoeba histolytica protein kinase domain containing protein 0.0069 0.0069 0.0162
Echinococcus granulosus tyrosine protein kinase csk 0.0067 0.0045 0.0095
Echinococcus granulosus insulin receptor 0.0215 0.1519 0.3202
Entamoeba histolytica protein kinase, putative 0.022 0.1575 1
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0084 0.0222 0.2026
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0091 0.0286 0.0604
Entamoeba histolytica hypothetical protein 0.0128 0.0655 0.3989
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0067 0.0045 0.0009
Loa Loa (eye worm) RGC/RGC protein kinase 0.0067 0.0045 0.0045
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0067 0.0045 0.0045
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Echinococcus granulosus tyrosine protein kinase Blk 0.0337 0.2736 0.5768
Schistosoma mansoni protein kinase C mu 0.0104 0.0422 0.1053
Trichomonas vaginalis conserved hypothetical protein 0.0128 0.0655 0.513
Loa Loa (eye worm) SH2 domain-containing protein 0.0137 0.0744 0.0744
Echinococcus multilocularis cyclin dependent kinase 1 0.0066 0.0044 0.005
Trypanosoma cruzi hypothetical protein, conserved 0.013 0.0673 0.4106
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0137 0.0744 0.1856
Onchocerca volvulus 0.0137 0.0744 0.0744
Loa Loa (eye worm) TK protein kinase 0.0067 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0067 0.0045 0.0045
Brugia malayi Variant SH3 domain containing protein 0.0128 0.0655 0.0655
Entamoeba histolytica protein kinase, putative 0.0067 0.0045 0.0005
Brugia malayi Protein kinase domain containing protein 0.0255 0.1918 0.1918
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.1208 0.3015
Echinococcus granulosus contactin 0.0063 0.0012 0.0026
Schistosoma mansoni tyrosine protein kinase 0.0067 0.0045 0.0112
Echinococcus granulosus SH2 domain containing protein 7 0.0137 0.0744 0.1568
Echinococcus granulosus c-Jun N-terminal kinases 0.028 0.217 0.4575
Schistosoma mansoni tyrosine kinase 0.0354 0.2901 0.7238
Echinococcus granulosus TGF beta receptor type 1 0.0099 0.037 0.078
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0482 0.4183 0.8819
Echinococcus granulosus ephrin type A receptor 4 A 0.0067 0.0045 0.0095
Schistosoma mansoni protein kinase 0.0099 0.037 0.0923
Brugia malayi SH2 domain containing protein 0.0137 0.0744 0.0744
Onchocerca volvulus 0.0128 0.0655 0.0655
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0137 0.0744 0.0744
Entamoeba histolytica protein kinase, putative 0.0067 0.0045 0.0005
Trypanosoma brucei Pseudokinase, putative 0.0067 0.0045 0.0005
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0067 0.0045 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0301 0.075
Echinococcus multilocularis raf serine:threonine protein kinase 0.0084 0.0216 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0128 0.0655 0.513
Schistosoma mansoni ephrin receptor 0.0067 0.0045 0.0112
Schistosoma mansoni tyrosine kinase 0.0067 0.0045 0.0112
Loa Loa (eye worm) SH2 domain-containing protein 0.0137 0.0744 0.0744
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0063 0.0012 0.0014
Schistosoma mansoni protein kinase 0.0067 0.0045 0.0112
Schistosoma mansoni tyrosine kinase 0.0067 0.0045 0.0112
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0125 0.063 0.1329
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0067 0.0045 0.0045
Onchocerca volvulus 0.0091 0.0284 0.0284
Echinococcus granulosus tyrosine protein kinase Fyn 0.0465 0.4007 0.8449
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0067 0.0045 0.0112
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0067 0.0045 0.0051
Echinococcus multilocularis dual specificity protein kinase clk2 0.0155 0.0922 0.1052
Entamoeba histolytica protein kinase, putative 0.0067 0.0045 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.101 0.252
Schistosoma mansoni serine/threonine protein kinase 0.0155 0.0922 0.23
Echinococcus multilocularis SH2 motif 0.0137 0.0744 0.0849
Leishmania major protein kinase, putative 0.0067 0.0045 0.0005
Entamoeba histolytica protein kinase domain containing protein 0.022 0.1575 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0201 0.1382 0.1578
Schistosoma mansoni serine/threonine protein kinase 0.0063 0.0008 0.002
Echinococcus multilocularis protein kinase shaggy 0.0126 0.064 0.073
Brugia malayi Protein kinase domain containing protein 0.022 0.1575 0.1575
Echinococcus granulosus Protein kinase C brain isozyme 0.0063 0.0008 0.0017
Schistosoma mansoni shc transforming protein 0.0137 0.0744 0.1856
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0135 0.0724 0.775
Trypanosoma cruzi hypothetical protein, conserved 0.0128 0.0655 0.3989
Schistosoma mansoni protein kinase 0.0067 0.0045 0.0112
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0465 0.4007 0.4574
Brugia malayi hypothetical protein 0.0067 0.0045 0.0045
Schistosoma mansoni vav2 0.0158 0.0954 0.2381
Giardia lamblia Kinase, AGC PKA 0.0109 0.0463 0.3523
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0067 0.0045 0.0112
Schistosoma mansoni protein kinase 0.0148 0.0855 0.2133
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0199 0.1363 0.1556
Trypanosoma cruzi protein kinase, putative 0.0067 0.0045 0.0005
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0155 0.0922 0.5733
Entamoeba histolytica hypothetical protein 0.022 0.1575 1
Brugia malayi probable protein kinase 0.0143 0.0807 0.0807
Schistosoma mansoni C-fyn 0.0128 0.0655 0.1634
Echinococcus granulosus tyrosine protein kinase Src42A 0.0465 0.4007 0.8449
Loa Loa (eye worm) hypothetical protein 0.0087 0.0245 0.0245
Brugia malayi Tyrosine-protein kinase PR2 0.0067 0.0045 0.0045
Brugia malayi ephrin receptor 1 precursor 0.0067 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0063 0.0012 0.0012
Loa Loa (eye worm) AGC/PKA protein kinase 0.0109 0.0463 0.0463
Brugia malayi integrin-linked kinase 0.0067 0.0045 0.0045
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0081 0.0189 0.0189
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0428 0.1069
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0133 0.0709 0.1495
Loa Loa (eye worm) TK/FER protein kinase 0.0067 0.0045 0.0045
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0068 0.0063 0.0133
Echinococcus multilocularis Spectrin alpha actinin 0.0128 0.0655 0.0747
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0067 0.0045 0.0005
Entamoeba histolytica hypothetical protein, conserved 0.0067 0.0045 0.0005
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0265 0.2016 0.2016
Echinococcus granulosus N chimaerin 0.0154 0.0915 0.193
Echinococcus granulosus NCK adaptor protein 0.0265 0.2016 0.425
Entamoeba histolytica tyrosine kinase, putative 0.0067 0.0045 0.0005
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0067 0.0045 0.0005
Schistosoma mansoni hypothetical protein 0.0067 0.0045 0.0112
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Loa Loa (eye worm) hypothetical protein 0.0137 0.0744 0.0744
Trichomonas vaginalis TKL family protein kinase 0.0067 0.005 0.0052
Trichomonas vaginalis p67phox protein, putative 0.0128 0.0655 0.513
Echinococcus multilocularis transfer RNA-Thr 0.0255 0.1918 0.219
Loa Loa (eye worm) hypothetical protein 0.0137 0.0744 0.0744
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0109 0.0463 0.2739
Echinococcus multilocularis death associated protein kinase 1 0.0943 0.8761 1
Schistosoma mansoni protein kinase 0.0143 0.0807 0.2015
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Schistosoma mansoni apoptosis stimulating of P53 0.0128 0.0655 0.1634
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Schistosoma mansoni protein kinase 0.0086 0.0238 0.0594
Brugia malayi Immunoglobulin I-set domain containing protein 0.0063 0.0012 0.0012
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0137 0.0744 0.1568
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0067 0.0045 0.0005
Brugia malayi hypothetical protein 0.0232 0.1695 0.1695
Echinococcus multilocularis SH2 domain containing protein 7 0.0137 0.0744 0.0849
Echinococcus multilocularis neuroglian 0.0063 0.0012 0.0014
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0067 0.0045 0.0045
Entamoeba histolytica protein kinase, putative 0.0067 0.0045 0.0005
Giardia lamblia Kinase, AGC AKT 0.0113 0.0509 0.3906
Echinococcus multilocularis insulin receptor 0.0215 0.1519 0.1734
Loa Loa (eye worm) hypothetical protein 0.0137 0.0744 0.0744
Echinococcus multilocularis tyrosine protein kinase csk 0.0067 0.0045 0.0051
Giardia lamblia Kinase, NEK 0.0135 0.0724 0.5715
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0067 0.0045 0.0112
Echinococcus granulosus roundabout 2 0.0063 0.0012 0.0026
Echinococcus multilocularis protein kinase 0.0067 0.0045 0.0051
Entamoeba histolytica cysteine surface protein, putative 0.0067 0.0045 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Loa Loa (eye worm) hypothetical protein 0.0128 0.0655 0.0655
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0067 0.0045 0.0005
Loa Loa (eye worm) TK/RYK protein kinase 0.0067 0.0045 0.0045
Entamoeba histolytica tyrosine kinase, putative 0.0067 0.0045 0.0005
Schistosoma mansoni tyrosine kinase 0.0302 0.2385 0.5952
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0164 0.101 0.101
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0137 0.0744 0.0849
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Echinococcus granulosus endophilin A3 0.0128 0.0655 0.138
Brugia malayi serine/threonine kinase 12 0.0145 0.083 0.083
Echinococcus multilocularis activated cdc42 kinase 1 0.0255 0.1918 0.219
Schistosoma mansoni cell polarity protein 0.0128 0.0655 0.1634
Echinococcus multilocularis growth factor receptor bound protein 2 0.0265 0.2016 0.2301
Giardia lamblia Kinase, STE STE20 0.0186 0.1234 1
Toxoplasma gondii protein kinase domain-containing protein 0.0067 0.0045 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Loa Loa (eye worm) TK/ALK protein kinase 0.065 0.5846 0.5846
Plasmodium falciparum NIMA related kinase 1 0.0135 0.0724 0.775
Brugia malayi Immunoglobulin I-set domain containing protein 0.0063 0.0012 0.0012
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0105 0.0428 0.0428
Echinococcus multilocularis roundabout 2 0.0063 0.0012 0.0014
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0203 0.1406 0.1605
Loa Loa (eye worm) TK/FER protein kinase 0.0203 0.1406 0.1406
Brugia malayi Variant SH3 domain containing protein 0.0128 0.0655 0.0655
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0063 0.0012 0.0014
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0232 0.1695 0.3574
Schistosoma mansoni tyrosine kinase 0.0179 0.1164 0.2904
Echinococcus granulosus tyrosine protein kinase csk 0.0067 0.0045 0.0095
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Trichomonas vaginalis STE family protein kinase 0.0135 0.0724 0.5715
Echinococcus granulosus activated cdc42 kinase 1 0.0255 0.1918 0.4045
Entamoeba histolytica tyrosin kinase, putative 0.0067 0.0045 0.0005
Echinococcus multilocularis SH2 motif 0.0137 0.0744 0.0849
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0098 0.036 0.0898
Schistosoma mansoni tyrosine kinase 0.0067 0.0045 0.0112
Loa Loa (eye worm) hypothetical protein 0.0067 0.0045 0.0045
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0465 0.4007 0.8449
Echinococcus granulosus cyclin dependent kinase 19 0.0167 0.1039 0.2192
Echinococcus granulosus neuroglian 0.0126 0.0636 0.1342
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Echinococcus multilocularis rho associated protein kinase 0.0183 0.1208 0.1379
Schistosoma mansoni tyrosine kinase 0.0356 0.2929 0.7309
Schistosoma mansoni tyrosine kinase 0.0067 0.0045 0.0112
Entamoeba histolytica protein kinase, putative 0.0155 0.0921 0.5728
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0141 0.0786 0.0786
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0265 0.2016 0.2016
Echinococcus granulosus neuroglian 0.0063 0.0012 0.0026
Loa Loa (eye worm) TK/FER protein kinase 0.0203 0.1406 0.1406
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Brugia malayi Variant SH3 domain containing protein 0.0265 0.2016 0.2016
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0109 0.0463 0.0529
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0148 0.0855 0.0855
Entamoeba histolytica tyrosine kinase, putative 0.0067 0.0045 0.0005
Echinococcus multilocularis mitogen activated protein kinase 14 0.0161 0.0983 0.1123
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0067 0.0045 0.0005
Giardia lamblia Kinase, CMGC GSK 0.0126 0.064 0.5006
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Echinococcus multilocularis protein kinase 0.0067 0.0045 0.0051
Echinococcus granulosus tyrosine protein kinase 0.0067 0.0045 0.0095
Trichomonas vaginalis protein tyrosine kinase, putative 0.0067 0.0045 0.0007
Giardia lamblia Kinase, NEK 0.0135 0.0724 0.5715
Brugia malayi Protein kinase domain containing protein 0.0203 0.1406 0.1406
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0067 0.0045 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Echinococcus granulosus cyclin dependent kinase 0.0066 0.0044 0.0093
Loa Loa (eye worm) TK protein kinase 0.0067 0.0045 0.0045
Onchocerca volvulus 0.0069 0.0074 0.0074
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0154 0.0915 0.2284
Loa Loa (eye worm) hypothetical protein 0.0115 0.0524 0.0524
Echinococcus granulosus mitogen activated protein kinase 14 0.0161 0.0983 0.2074
Echinococcus multilocularis SH2 motif 0.0137 0.0744 0.0849
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Brugia malayi Guanylyl cyclase protein 23 0.0067 0.0045 0.0045
Echinococcus granulosus roundabout 2 0.0161 0.099 0.2086
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0137 0.0744 0.0744
Echinococcus granulosus tyrosine protein kinase Src64B 0.0465 0.4007 0.8449
Echinococcus granulosus dual specificity mitogen activated protein 0.0186 0.1234 0.2602
Entamoeba histolytica hypothetical protein 0.0067 0.0049 0.0033
Echinococcus multilocularis transfer RNA-Ala 0.0128 0.0655 0.0747
Brugia malayi STAT protein, DNA binding domain containing protein 0.0137 0.0744 0.0744
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0104 0.0422 0.0422
Loa Loa (eye worm) TK/FER protein kinase 0.0203 0.1406 0.1406
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0087 0.0251 0.0251
Brugia malayi Protein kinase domain containing protein 0.0167 0.1039 0.1039
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.0128 0.0655 0.0655
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0067 0.0045 0.0005
Brugia malayi SH2 domain containing protein 0.0137 0.0744 0.0744
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Toxoplasma gondii protein kinase 0.0067 0.0045 0.0009
Schistosoma mansoni tyrosine kinase 0.0067 0.0045 0.0112
Schistosoma mansoni tyrosine kinase 0.0067 0.0045 0.0112
Brugia malayi Tyrosine-protein kinase abl-1 0.0421 0.3573 0.3573
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0109 0.0463 0.4777
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0696 0.6308 0.6308
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.1039 0.2594
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0067 0.0045 0.0095
Echinococcus granulosus suppressor of cytokine signaling 6 0.0137 0.0744 0.1568
Echinococcus multilocularis slit robo rho gtpase activating protein 1 0.0128 0.0655 0.0747
Echinococcus granulosus aurora kinase A 0.0145 0.083 0.1749
Loa Loa (eye worm) hypothetical protein 0.0067 0.0045 0.0045
Echinococcus granulosus cyclin dependent kinase 9 0.0078 0.0158 0.0334
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0155 0.0922 0.0922
Schistosoma mansoni tyrosine kinase 0.0067 0.0047 0.0117
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0067 0.0045 0.0051
Schistosoma mansoni sh3-containing grb2-like protein 1 (endophilin II) 0.0128 0.0655 0.1634
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0126 0.064 0.073
Onchocerca volvulus 0.0087 0.0245 0.0245
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0126 0.064 0.6789
Entamoeba histolytica PH domain containing protein kinase, putative 0.0113 0.0502 0.2992
Trichomonas vaginalis AGC family protein kinase 0.0067 0.0045 0.0007
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0153 0.0902 0.1902
Loa Loa (eye worm) p53BP2 0.0128 0.0655 0.0655
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0066 0.0044 0.0093
Echinococcus multilocularis tyrosine protein kinase Blk 0.0337 0.2736 0.3123
Schistosoma mansoni tensin 0.0137 0.0744 0.1856
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0428 0.1069
Brugia malayi Protein kinase domain containing protein 0.0357 0.2935 0.2935
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0161 0.0983 0.6137
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0067 0.0045 0.0112
Brugia malayi Sex muscle abnormal protein 5 0.0265 0.2016 0.2016
Entamoeba histolytica serine/threonine kinase, putative 0.0067 0.0045 0.0005
Entamoeba histolytica hypothetical protein 0.0067 0.0045 0.0005
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0154 0.0915 0.1045
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0067 0.0045 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0067 0.0045 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0045 0.0007
Loa Loa (eye worm) TK/FAK protein kinase 0.0357 0.2935 0.2935
Echinococcus multilocularis protein kinase c iota type 0.0063 0.0008 0.0009
Loa Loa (eye worm) TK/FER protein kinase 0.0203 0.1406 0.1406
Onchocerca volvulus Tyrosine kinase homolog 0.0607 0.5418 0.5418
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0128 0.0655 0.0655
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0104 0.0422 0.0422
Onchocerca volvulus 0.013 0.0673 0.0673
Trichomonas vaginalis AGC family protein kinase 0.0145 0.083 0.6601
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0137 0.0744 0.0849
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0199 0.1363 0.2874
Entamoeba histolytica protein kinase, putative 0.0145 0.083 0.5132
Loa Loa (eye worm) TK protein kinase 0.0067 0.0045 0.0045
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Entamoeba histolytica tyrosine kinase, putative 0.0067 0.0045 0.0005
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0232 0.1695 0.1935
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0067 0.0045 0.0045
Brugia malayi SH2 domain containing protein 0.0203 0.1406 0.1406
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Onchocerca volvulus 0.0137 0.0744 0.0744
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Entamoeba histolytica tyrosine kinase, putative 0.0067 0.0045 0.0005
Entamoeba histolytica tyrosine kinase, putative 0.0067 0.0045 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0045 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Entamoeba histolytica hypothetical protein 0.0128 0.0655 0.3989
Loa Loa (eye worm) TK/FER protein kinase 0.0067 0.0045 0.0045
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Schistosoma mansoni tensin-related 0.0137 0.0744 0.1856
Loa Loa (eye worm) guanylate kinase 0.013 0.0677 0.0677
Echinococcus multilocularis tyrosine kinase 0.0067 0.0045 0.0051
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Echinococcus granulosus natriuretic peptide receptor 1 0.0067 0.0045 0.0095
Onchocerca volvulus 0.0166 0.1031 0.1031
Schistosoma mansoni tyrosine kinase 0.0331 0.2678 0.6682
Echinococcus granulosus protein kinase c iota type 0.0063 0.0008 0.0017
Entamoeba histolytica protein kinase domain containing protein 0.0126 0.064 0.3892
Schistosoma mansoni serine/threonine protein kinase 0.0067 0.0045 0.0112
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Echinococcus multilocularis dual specificity mitogen activated protein 0.0186 0.1234 0.1409
Schistosoma mansoni eps8-related protein 0.0128 0.0655 0.1634
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0199 0.1363 0.1363
Entamoeba histolytica tyrosine kinase, putative 0.0067 0.0045 0.0005
Loa Loa (eye worm) hypothetical protein 0.0137 0.0744 0.0744
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0067 0.0045 0.0095
Giardia lamblia Kinase, NEK 0.0067 0.0045 0.0007
Echinococcus multilocularis kinase suppressor of Ras 1 0.0067 0.0045 0.0051
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Echinococcus multilocularis roundabout 2 0.0161 0.099 0.1129
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0145 0.083 0.1749
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0139 0.0766 0.1616
Echinococcus granulosus mitogen activated protein kinase 11 0.0161 0.0983 0.2074
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0786 0.1961
Echinococcus granulosus tyrosine kinase 0.0067 0.0045 0.0095
Schistosoma mansoni protein tyrosine kinase 0.0067 0.0045 0.0112
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.022 0.1575 1
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0126 0.0636 0.0636
Entamoeba histolytica PH domain containing protein kinase, putative 0.0113 0.0502 0.2992
Loa Loa (eye worm) hypothetical protein 0.0067 0.0045 0.0045
Brugia malayi Variant SH3 domain containing protein 0.0128 0.0655 0.0655
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0045 0.0007
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0137 0.0744 0.0849
Brugia malayi hypothetical protein 0.0203 0.1406 0.1406
Loa Loa (eye worm) hypothetical protein 0.0067 0.0045 0.0045
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Brugia malayi Protein kinase domain containing protein 0.0087 0.0251 0.0251
Echinococcus granulosus intersectin 2 0.013 0.0673 0.1418
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0145 0.083 0.8951
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Echinococcus multilocularis neuroglian 0.0126 0.0636 0.0726
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0199 0.1363 0.1363
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0045 0.0007
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0155 0.0922 0.5733
Brugia malayi Protein kinase domain containing protein 0.0201 0.1382 0.1382
Plasmodium vivax tyrosine kinase-like protein, putative 0.0067 0.0045 0.0009
Onchocerca volvulus 0.0067 0.0045 0.0045
Echinococcus multilocularis receptor type guanylyl cyclase 0.0067 0.0045 0.0051
Schistosoma mansoni tyrosine kinase 0.0133 0.0709 0.1769
Trichomonas vaginalis conserved hypothetical protein 0.0128 0.0655 0.513
Echinococcus granulosus expressed protein 0.0128 0.0655 0.138
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0092 0.0301 0.0343
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0067 0.0045 0.0045
Trypanosoma cruzi aurora B kinase, putative 0.0145 0.083 0.5132
Schistosoma mansoni hypothetical protein 0.0128 0.0655 0.1634
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Loa Loa (eye worm) protein-tyrosine kinase 0.0128 0.0655 0.0655
Schistosoma mansoni protein kinase 0.0186 0.1234 0.3079
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0137 0.0744 0.0849
Trypanosoma cruzi paraflagellar rod protein 5, putative 0.0128 0.0655 0.3989
Echinococcus granulosus epidermal growth factor receptor 0.0133 0.0709 0.1495
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0117 0.0549 0.1158
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0067 0.0045 0.0051
Loa Loa (eye worm) hypothetical protein 0.0069 0.0074 0.0074
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0179 0.1164 0.1328
Entamoeba histolytica protein kinase, putative 0.0067 0.0045 0.0005
Loa Loa (eye worm) TK protein kinase 0.0067 0.0045 0.0045
Loa Loa (eye worm) TK protein kinase 0.0207 0.144 0.144
Leishmania major hypothetical protein, conserved 0.013 0.0673 0.4106
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0063 0.0008 0.0009
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.022 0.1575 1
Echinococcus granulosus tyrosine protein kinase pr2 0.0067 0.0045 0.0095
Echinococcus granulosus SH2 motif 0.0137 0.0744 0.1568
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0155 0.0922 0.5733
Onchocerca volvulus 0.0128 0.0655 0.0655
Brugia malayi Receptor family ligand binding region containing protein 0.0067 0.0045 0.0045
Toxoplasma gondii AGC kinase 0.0109 0.0463 0.4777
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0067 0.0045 0.0007
Plasmodium falciparum protein kinase, putative 0.0084 0.0222 0.2026
Entamoeba histolytica receptor protein kinase, putative 0.0067 0.0045 0.0005
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0109 0.0463 0.2739
Echinococcus multilocularis ephrin type A receptor 4 A 0.0067 0.0045 0.0051
Echinococcus granulosus tyrosine protein kinase Fyn 0.0465 0.4007 0.8449
Plasmodium falciparum serine/threonine protein kinase, putative 0.0145 0.083 0.8951
Schistosoma mansoni atypical protein kinase C 0.0063 0.0008 0.002
Entamoeba histolytica hypothetical protein 0.0067 0.0045 0.0005
Trichomonas vaginalis STE family protein kinase 0.0186 0.1234 1
Brugia malayi Protein kinase domain containing protein 0.0203 0.1406 0.1406
Schistosoma mansoni tyrosine kinase 0.0067 0.0045 0.0112
Loa Loa (eye worm) AUR protein kinase 0.0145 0.083 0.083
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0067 0.0045 0.0045
Echinococcus granulosus activated cdc42 kinase 1 0.0255 0.1918 0.4045
Schistosoma mansoni serine/threonine protein kinase 0.022 0.1575 0.3929
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0149 0.0865 0.0865
Echinococcus granulosus roundabout 2 0.0063 0.0012 0.0026
Loa Loa (eye worm) hypothetical protein 0.0067 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0067 0.0045 0.0045
Loa Loa (eye worm) TK/FER protein kinase 0.0203 0.1406 0.1406
Entamoeba histolytica hypothetical protein 0.0067 0.0049 0.0033
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0067 0.0045 0.0009
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0465 0.4007 0.4574
Brugia malayi tRNA modification GTPase TrmE family protein 0.0137 0.0744 0.0744
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0141 0.0783 0.0783
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0265 0.2016 0.503
Loa Loa (eye worm) TK/CSK protein kinase 0.0067 0.0045 0.0045
Schistosoma mansoni tyrosine kinase 0.0215 0.1519 0.379
Schistosoma mansoni protein kinase 0.0145 0.083 0.207
Loa Loa (eye worm) hypothetical protein 0.0188 0.1256 0.1256
Loa Loa (eye worm) TK protein kinase 0.02 0.1375 0.1375
Onchocerca volvulus 0.0203 0.1406 0.1406
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0084 0.0222 0.1162
Entamoeba histolytica protein kinase, putative 0.0067 0.0045 0.0005
Loa Loa (eye worm) TK protein kinase 0.0067 0.0045 0.0045
Onchocerca volvulus 0.0067 0.0045 0.0045
Brugia malayi protein C17H12.11 0.0069 0.0074 0.0074
Schistosoma mansoni serine/threonine protein kinase 0.0063 0.0008 0.002
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0045 0.0007
Onchocerca volvulus 0.0067 0.0045 0.0045
Schistosoma mansoni ephrin receptor 0.0083 0.0209 0.0521
Echinococcus granulosus SH2 motif 0.0137 0.0744 0.1568
Trichomonas vaginalis conserved hypothetical protein 0.0128 0.0655 0.513
Brugia malayi Immunoglobulin I-set domain containing protein 0.0696 0.6308 0.6308
Trypanosoma brucei Flagellum attachment zone protein 20 0.0067 0.0045 0.0005
Brugia malayi protein-tyrosine kinase 0.0337 0.2736 0.2736
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0045 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0094 0.0321 0.0678
Entamoeba histolytica hypothetical protein 0.0128 0.0655 0.3989
Entamoeba histolytica hypothetical protein 0.0067 0.0045 0.0005
Echinococcus granulosus tyrosine protein kinase HCK 0.02 0.1375 0.2898
Echinococcus granulosus breast cancer anti estrogen resistance protein 0.0128 0.0655 0.138
Echinococcus granulosus tyrosine kinase 0.0203 0.1406 0.2964
Echinococcus multilocularis Immunoglobulin 0.0098 0.036 0.0411
Echinococcus granulosus hypothetical protein 0.0137 0.0744 0.1568
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0094 0.0321 0.0367
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0132 0.0693 0.173
Schistosoma mansoni tyrosine kinase 0.0203 0.1406 0.3509
Leishmania major protein kinase, putative 0.0155 0.0922 0.5733
Loa Loa (eye worm) TK/ABL protein kinase 0.0439 0.3747 0.3747
Echinococcus granulosus hematopoietic lineage cell specific protein 0.0128 0.0655 0.138
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0098 0.036 0.0411
Brugia malayi protein kinase C II. 0.0063 0.0008 0.0008
Entamoeba histolytica protein kinase, putative 0.0067 0.0045 0.0005
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0066 0.0044 0.0044
Echinococcus multilocularis signal transduction protein lnk realted 0.0137 0.0744 0.0849
Onchocerca volvulus 0.0137 0.0744 0.0744
Echinococcus granulosus retinal guanylyl cyclase 2 0.0067 0.0045 0.0095
Echinococcus granulosus slit robo rho gtpase activating protein 1 0.0128 0.0655 0.138
Echinococcus multilocularis tyrosine protein kinase Srms 0.0337 0.2736 0.3123
Onchocerca volvulus LIM and SH3 domain protein homolog 0.0128 0.0656 0.0656
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Entamoeba histolytica hypothetical protein 0.0067 0.0045 0.0005
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Echinococcus granulosus suppressor of cytokine signaling 7 0.0137 0.0744 0.1568
Loa Loa (eye worm) hypothetical protein 0.0157 0.0949 0.0949
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0067 0.0045 0.0112
Entamoeba histolytica hypothetical protein 0.0067 0.0045 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Schistosoma mansoni tyrosine kinase 0.0113 0.0511 0.1275
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.1363 0.3401
Entamoeba histolytica serine/threonine kinase, putative 0.0067 0.0045 0.0005
Loa Loa (eye worm) STAT protein 0.0137 0.0744 0.0744
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0066 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0128 0.0655 0.0655
Onchocerca volvulus 0.0203 0.1406 0.1406
Entamoeba histolytica protein kinase, putative 0.0128 0.0655 0.3989
Giardia lamblia Kinase 0.0067 0.0045 0.0007
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0154 0.0915 0.0915
Trichomonas vaginalis STE family protein kinase 0.0067 0.0045 0.0007
Loa Loa (eye worm) hypothetical protein 0.0125 0.063 0.063
Brugia malayi SH2 domain containing protein 0.0137 0.0744 0.0744
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0084 0.0223 0.047
Schistosoma mansoni slit-robo rho gtpase activating protein 0.0128 0.0655 0.1634
Loa Loa (eye worm) hypothetical protein 0.0137 0.0744 0.0744
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0067 0.0045 0.0005
Entamoeba histolytica hypothetical protein, conserved 0.0128 0.0655 0.3989
Schistosoma mansoni growth factor receptor-bound protein 0.0266 0.2034 0.5075
Loa Loa (eye worm) TK/FER protein kinase 0.0067 0.0045 0.0045
Schistosoma mansoni tyrosine kinase 0.0139 0.0766 0.1912
Toxoplasma gondii aurora kinase 0.0145 0.083 0.8951
Entamoeba histolytica serine/threonine kinase, putative 0.0067 0.0045 0.0005
Leishmania major hypothetical protein, conserved 0.0067 0.0045 0.0005
Entamoeba histolytica hypothetical protein 0.0067 0.0045 0.0005
Loa Loa (eye worm) hypothetical protein 0.0128 0.0655 0.0655
Echinococcus granulosus tyrosine protein kinase csk 0.0067 0.0045 0.0095
Loa Loa (eye worm) hypothetical protein 0.0098 0.036 0.036
Onchocerca volvulus 0.0183 0.1208 0.1208
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0126 0.064 0.1597
Echinococcus granulosus tyrosine protein kinase ABL1 0.0439 0.3747 0.7899
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0161 0.0983 0.6137
Loa Loa (eye worm) TK/EPH protein kinase 0.0067 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0067 0.0045 0.0045
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Brugia malayi Fes/CIP4 homology domain containing protein 0.0128 0.0655 0.0655
Entamoeba histolytica tyrosine kinase, putative 0.0067 0.0045 0.0005
Echinococcus multilocularis dual specificity 0.022 0.1575 0.1797
Echinococcus multilocularis breast cancer anti estrogen resistance protein 0.0128 0.0655 0.0747
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0067 0.0045 0.0045
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0141 0.0786 0.1657
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0063 0.0008 0.0008
Loa Loa (eye worm) TK protein kinase 0.0067 0.0045 0.0045
Schistosoma mansoni formin binding protein and related proteins 0.0128 0.0655 0.1634
Entamoeba histolytica tyrosine kinase, putative 0.0067 0.0045 0.0005
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0067 0.0045 0.0112
Echinococcus multilocularis mitogen activated protein kinase 11 0.0161 0.0983 0.1123
Plasmodium falciparum tyrosine kinase-like protein 0.0067 0.0045 0.0009
Entamoeba histolytica protein kinase , putative 0.0145 0.083 0.5132
Brugia malayi SH2 domain containing protein 0.0137 0.0744 0.0744
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0067 0.0045 0.0095
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0463 0.3523
Leishmania major protein kinase, putative 0.0155 0.0922 0.5733
Echinococcus multilocularis cyclin dependent kinase 7 0.0105 0.0428 0.0489
Loa Loa (eye worm) SH2 domain-containing protein 0.0137 0.0744 0.0744
Schistosoma mansoni tyrosine kinase 0.0084 0.0222 0.0554
Echinococcus multilocularis rho guanine nucleotide exchange factor 7 0.0128 0.0655 0.0747
Giardia lamblia Kinase, CMGC CLK 0.0155 0.0922 0.7374
Loa Loa (eye worm) RGC/RGC protein kinase 0.0067 0.0045 0.0045
Onchocerca volvulus 0.0067 0.0045 0.0045
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0186 0.1238 0.1413
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0482 0.4183 0.4775
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0135 0.0724 0.775
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0067 0.0045 0.0005
Echinococcus granulosus cyclin dependent kinase 9 0.0069 0.0069 0.0145
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0203 0.1406 0.2964
Schistosoma mansoni tyrosine kinase 0.0133 0.0709 0.1769
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0439 0.3747 0.4276
Loa Loa (eye worm) hypothetical protein 0.0137 0.0744 0.0744
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0067 0.0045 0.0007
Onchocerca volvulus 0.0203 0.1406 0.1406
Loa Loa (eye worm) hypothetical protein 0.0069 0.0074 0.0074
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0109 0.0463 0.0529
Echinococcus multilocularis tensin 0.0137 0.0744 0.0849
Entamoeba histolytica protein kinase, putative 0.0067 0.0045 0.0005
Brugia malayi serine/threonine-protein kinase PAK 7 0.0226 0.163 0.163
Loa Loa (eye worm) TK/FER protein kinase 0.0067 0.0045 0.0045
Echinococcus granulosus defective proboscis extension response 0.0098 0.036 0.0759
Echinococcus granulosus fch and double sh3 domains protein 2 0.0128 0.0655 0.138
Schistosoma mansoni protein kinase 0.0067 0.0045 0.0112
Loa Loa (eye worm) TK protein kinase 0.0067 0.0045 0.0045
Loa Loa (eye worm) TK/FER protein kinase 0.0203 0.1406 0.1406
Schistosoma mansoni protein kinase 0.0067 0.0045 0.0112
Trypanosoma brucei protein kinase, putative 0.0126 0.064 0.3892
Plasmodium vivax protein kinase, putative 0.0067 0.0045 0.0009
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Entamoeba histolytica protein kinase, putative 0.0067 0.0045 0.0005
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0137 0.0744 0.0744
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0539 0.4743 1
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0128 0.0655 0.0747
Echinococcus granulosus cyclin dependent kinase 7 0.0105 0.0428 0.0903
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0186 0.1234 0.1234
Onchocerca volvulus 0.0148 0.0854 0.0854
Echinococcus multilocularis natriuretic peptide receptor 1 0.0067 0.0045 0.0051
Echinococcus multilocularis Immunoglobulin 0.0098 0.036 0.0411
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0186 0.1234 0.7774
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0149 0.0865 0.1823
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0231 0.1683 0.1921
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0126 0.064 0.3892
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0179 0.1164 0.1328
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0109 0.0463 0.2739
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0067 0.0045 0.0005
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0167 0.1039 0.1039
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0067 0.0045 0.0005
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0126 0.064 0.064
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0067 0.0045 0.0005
Plasmodium falciparum tyrosine kinase-like protein 0.0067 0.0045 0.0009
Schistosoma mansoni protein kinase 0.0261 0.1976 0.4932
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0153 0.0902 0.0902
Onchocerca volvulus 0.0137 0.0744 0.0744
Trichomonas vaginalis AGC family protein kinase 0.0135 0.0724 0.5715
Schistosoma mansoni growth factor receptor-bound protein 0.0265 0.2016 0.503
Brugia malayi Protein kinase domain containing protein 0.0148 0.0855 0.0855
Entamoeba histolytica BAR/SH3 domain containing protein 0.0128 0.0655 0.3989
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0044 0.011
Brugia malayi Protein kinase domain containing protein 0.0208 0.1453 0.1453
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0201 0.1382 0.1382
Loa Loa (eye worm) hypothetical protein 0.0115 0.0524 0.0524
Trichomonas vaginalis neutrophil cytosolic factor 2, neutrophil NADPH oxidase factor, putative 0.0128 0.0655 0.513
Schistosoma mansoni nephrin 0.0063 0.0012 0.0031
Loa Loa (eye worm) hypothetical protein 0.0073 0.0104 0.0104
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0137 0.0744 0.0849
Onchocerca volvulus 0.1067 1 1
Schistosoma mansoni tyrosine kinase 0.0067 0.0045 0.0112
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0126 0.064 0.1349
Schistosoma mansoni signal transduction protein lnk-related 0.0137 0.0744 0.1856
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0067 0.0049 0.0033
Schistosoma mansoni adapter molecule crk 0.0265 0.2016 0.503
Echinococcus multilocularis tyrosine protein kinase csk 0.0067 0.0045 0.0051
Brugia malayi Raf kinase 0.0067 0.0045 0.0045
Echinococcus multilocularis expressed protein 0.0128 0.0655 0.0747
Entamoeba histolytica hypothetical protein, conserved 0.0128 0.0655 0.3989
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Brugia malayi hypothetical protein 0.0137 0.0744 0.0744
Brugia malayi cyclin-dependent kinase 9 0.0069 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0137 0.0744 0.0744
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0161 0.0983 0.6137
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0067 0.0045 0.0051
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0145 0.083 0.5132
Trichomonas vaginalis conserved hypothetical protein 0.0128 0.0655 0.513
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Echinococcus granulosus protein kinase 0.0086 0.0238 0.0502
Schistosoma mansoni tyrosine kinase 0.0215 0.1519 0.379
Schistosoma mansoni tyrosine kinase 0.0067 0.0045 0.0112
Trichomonas vaginalis STE family protein kinase 0.0186 0.1234 1
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0272 0.2092 0.2387
Brugia malayi serine/threonine-protein kinase 6 0.0145 0.083 0.083
Echinococcus multilocularis SHC transforming protein 3 0.0137 0.0744 0.0849
Schistosoma mansoni neuroglian 0.0063 0.0012 0.0031
Echinococcus granulosus tyrosine protein kinase Fyn 0.0465 0.4007 0.8449
Brugia malayi Spectrin alpha chain 0.0128 0.0655 0.0655
Brugia malayi Variant SH3 domain containing protein 0.0128 0.0655 0.0655
Brugia malayi Protein kinase domain containing protein 0.0199 0.1363 0.1363
Schistosoma mansoni vesicular amine transporter 0.0098 0.036 0.0898
Loa Loa (eye worm) thyroid receptor interactor 0.0128 0.0655 0.0655
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0465 0.4007 0.4574
Echinococcus multilocularis intersectin 2 0.013 0.0673 0.0768
Trichomonas vaginalis protein kinase atn1, putative 0.0067 0.0045 0.0007
Loa Loa (eye worm) TK/FER protein kinase 0.0067 0.0045 0.0045
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Brugia malayi Furin-like cysteine rich region family protein 0.0133 0.0709 0.0709
Echinococcus granulosus TGF-beta receptor type-1 0.0099 0.037 0.078
Brugia malayi Protein kinase domain containing protein 0.0203 0.1406 0.1406
Echinococcus granulosus growth factor receptor bound protein 2 0.0266 0.2034 0.4288
Loa Loa (eye worm) hypothetical protein 0.0137 0.0744 0.0744
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.022 0.1575 1
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0109 0.0463 0.0977
Brugia malayi Protein kinase domain containing protein 0.0215 0.1519 0.1519
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0109 0.0463 0.0529
Brugia malayi serine/threonine protein kinase 6 0.0145 0.083 0.083
Entamoeba histolytica tyrosin kinase, putative 0.0067 0.0045 0.0005
Giardia lamblia Protein 21.1 0.0067 0.0045 0.0007
Loa Loa (eye worm) hypothetical protein 0.0139 0.0766 0.0766
Echinococcus granulosus retinal guanylyl cyclase 2 0.0067 0.0045 0.0095
Entamoeba histolytica cell division protein kinase 2, putative 0.0075 0.0133 0.0583
Giardia lamblia Aurora kinase 0.0145 0.083 0.6601
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0075 0.0129 0.0273
Leishmania major protein kinase, putative 0.0145 0.083 0.5132
Brugia malayi Protein kinase domain containing protein 0.0203 0.1406 0.1406
Loa Loa (eye worm) hypothetical protein 0.0137 0.0745 0.0745
Loa Loa (eye worm) IKK protein kinase 0.1067 1 1
Trichomonas vaginalis STE family protein kinase 0.0186 0.1234 1
Echinococcus multilocularis endophilin A3 0.0128 0.0655 0.0747
Loa Loa (eye worm) hypothetical protein 0.0157 0.0949 0.0949
Loa Loa (eye worm) AUR protein kinase 0.0145 0.083 0.083
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0067 0.0045 0.0007
Onchocerca volvulus 0.0157 0.0949 0.0949
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0045 0.0007
Brugia malayi C-terminal src kinase protein 1 0.0067 0.0045 0.0045
Entamoeba histolytica protein kinase domain containing protein 0.0126 0.064 0.3892
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0044 0.011
Brugia malayi Variant SH3 domain containing protein 0.0128 0.0655 0.0655
Loa Loa (eye worm) hypothetical protein 0.0203 0.1398 0.1398
Brugia malayi Protein kinase domain containing protein 0.0533 0.4688 0.4688
Echinococcus granulosus epidermal growth factor receptor 0.0133 0.0709 0.1495
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0067 0.0045 0.0112
Schistosoma mansoni tyrosine kinase 0.0067 0.0045 0.0112
Brugia malayi Variant SH3 domain containing protein 0.0265 0.2016 0.2016
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.0069 0.0172
Loa Loa (eye worm) TK/FER protein kinase 0.0203 0.1406 0.1406
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0186 0.1234 0.7774
Echinococcus granulosus activin receptor type 0.05 0.4359 0.919
Schistosoma mansoni kinase 0.0069 0.0069 0.0172
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0337 0.2736 0.5768
Schistosoma mansoni protein kinase 0.0186 0.1238 0.309
Echinococcus multilocularis NCK adaptor protein 0.0266 0.2034 0.2321
Brugia malayi Protein kinase domain containing protein 0.065 0.5848 0.5848
Schistosoma mansoni tyrosine kinase 0.0067 0.0045 0.0112
Entamoeba histolytica protein kinase, putative 0.0067 0.0049 0.0033
Brugia malayi Serine/threonine-protein kinase SULU 0.0232 0.1695 0.1695
Onchocerca volvulus 0.0137 0.0744 0.0744
Echinococcus multilocularis tyrosine kinase 0.0203 0.1406 0.1605
Echinococcus multilocularis 0.0137 0.0745 0.085
Echinococcus multilocularis cyclin dependent kinase 19 0.0167 0.1039 0.1186
Brugia malayi Fibronectin type III domain containing protein 0.0115 0.0524 0.0524
Echinococcus multilocularis c src tyrosine kinase 0.0331 0.2678 0.3057
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0084 0.0222 0.1162
Schistosoma mansoni serine/threonine protein kinase 0.0208 0.1453 0.3627
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0067 0.0045 0.0005
Echinococcus multilocularis roundabout 2 0.0063 0.0012 0.0014
Giardia lamblia Kinase, NEK 0.0067 0.0045 0.0007
Loa Loa (eye worm) hypothetical protein 0.0067 0.0045 0.0045
Echinococcus multilocularis tyrosine protein kinase HCK 0.02 0.1375 0.1569
Brugia malayi bone morphogenetic protein type 1 receptor 0.0148 0.0855 0.0855
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0201 0.1382 0.2914
Schistosoma mansoni dreadlocks/dock 0.0128 0.0655 0.1634
Onchocerca volvulus 0.0203 0.1406 0.1406
Schistosoma mansoni signal transducing adapter molecule (stam) 0.0128 0.0655 0.1634
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Onchocerca volvulus 0.0067 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0265 0.2016 0.2016
Brugia malayi hypothetical protein 0.0067 0.0045 0.0045
Echinococcus granulosus dual specificity protein kinase clk2 0.0155 0.0922 0.1943
Echinococcus granulosus integrin linked protein kinase 0.0067 0.0045 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.028 0.217 0.5415
Schistosoma mansoni protein kinase 0.0067 0.0045 0.0112
Echinococcus multilocularis tyrosine protein kinase Abl 0.0421 0.3573 0.4078
Trichomonas vaginalis CMGC family protein kinase 0.0155 0.0922 0.7374
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0137 0.0744 0.0849
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0261 0.1976 0.2256
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0145 0.083 0.5132
Echinococcus multilocularis mitogen activated protein kinase 14 0.0161 0.0983 0.1123
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0109 0.0463 0.2739
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0067 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0175 0.112 0.112
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0109 0.0463 0.0463
Echinococcus granulosus twitchin 0.0144 0.0813 0.1715
Schistosoma mansoni tensin-related 0.0137 0.0744 0.1856
Loa Loa (eye worm) TK/DDR protein kinase 0.0067 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0145 0.0826 0.0826
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Brugia malayi cell division control protein 2 homolog 0.0066 0.0044 0.0044
Brugia malayi Immunoglobulin I-set domain containing protein 0.0063 0.0012 0.0012
Trichomonas vaginalis CMGC family protein kinase 0.0126 0.064 0.5006
Schistosoma mansoni serine/threonine protein kinase 0.0155 0.0922 0.23
Entamoeba histolytica hypothetical protein 0.0128 0.0655 0.3989
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0067 0.0045 0.0045
Schistosoma mansoni nck2/grb4 0.0265 0.2016 0.503
Loa Loa (eye worm) TK/ROR protein kinase 0.0094 0.0321 0.0321
Echinococcus granulosus hypothetical protein 0.0137 0.0745 0.157
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0149 0.0865 0.0865
Echinococcus granulosus Spectrin alpha actinin 0.0128 0.0655 0.138
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0145 0.083 0.0947
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0109 0.0463 0.2739
Entamoeba histolytica tyrosine kinase, putative 0.0067 0.0045 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Echinococcus multilocularis cyclin dependent kinase 0.0066 0.0044 0.005
Loa Loa (eye worm) hypothetical protein 0.0203 0.1406 0.1406
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0463 0.1156
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0109 0.0463 0.4777
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0154 0.0915 0.2284
Echinococcus granulosus rho-associated protein kinase 1 0.0183 0.1208 0.2547
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0149 0.0865 0.0987
Echinococcus multilocularis protein tyrosine kinase 0.0354 0.2901 0.3311
Echinococcus granulosus expressed conserved protein 0.0137 0.0744 0.1568
Brugia malayi SH2 domain containing protein 0.0203 0.1406 0.1406
Loa Loa (eye worm) hypothetical protein 0.0109 0.0463 0.0463
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0463 0.1156
Brugia malayi Guanylate kinase family protein 0.013 0.0677 0.0677
Echinococcus multilocularis activin receptor type 0.05 0.4359 0.4975
Loa Loa (eye worm) TK/FER protein kinase 0.0067 0.0045 0.0045
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0063 0.0012 0.0012
Echinococcus multilocularis N chimaerin 0.0154 0.0915 0.1045
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0086 0.0238 0.0238
Echinococcus multilocularis protein KINase family member (kin 25) 0.0139 0.0766 0.0875
Echinococcus multilocularis 0.0086 0.0238 0.0272
Echinococcus multilocularis cyclin dependent kinase 5 0.0066 0.0044 0.005
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Brugia malayi Peripheral plasma membrane protein CASK 0.013 0.0677 0.0677
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.022 0.1575 0.1575
Echinococcus granulosus cyclin dependent kinase 5 0.0066 0.0044 0.0093
Entamoeba histolytica serine/threonine kinase, putative 0.0067 0.0045 0.0005
Loa Loa (eye worm) TK/Met protein kinase 0.0067 0.0045 0.0045
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0109 0.0463 0.0977
Entamoeba histolytica serine/threonine kinase, putative 0.0067 0.0045 0.0005
Entamoeba histolytica tyrosine kinase, putative 0.0067 0.0045 0.0005
Onchocerca volvulus 0.0128 0.0655 0.0655
Echinococcus granulosus fibroblast growth factor receptor 4 0.0179 0.1164 0.2453
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0137 0.0744 0.0744
Loa Loa (eye worm) hypothetical protein 0.0117 0.0549 0.0549
Schistosoma mansoni protein kinase 0.0067 0.0045 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0128 0.0655 0.513
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0199 0.1363 0.1363
Loa Loa (eye worm) hypothetical protein 0.0128 0.0655 0.0655
Entamoeba histolytica protein kinase, putative 0.0145 0.083 0.5132
Loa Loa (eye worm) RGC/RGC protein kinase 0.0067 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0081 0.0193 0.0193
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0232 0.1695 0.1695
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0141 0.0786 0.0897
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0161 0.0983 0.0983
Echinococcus granulosus SH2 domain containing adapter protein F 0.0137 0.0744 0.1568
Schistosoma mansoni tensin 0.0137 0.0744 0.1856
Trichomonas vaginalis AGC family protein kinase 0.0145 0.083 0.6601
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Loa Loa (eye worm) hypothetical protein 0.0099 0.0364 0.0364
Leishmania major protein kinase A catalytic subunit isoform 1 0.0109 0.0463 0.2739
Brugia malayi Protein kinase domain containing protein 0.0203 0.1406 0.1406
Echinococcus multilocularis cyclin dependent kinase 9 0.0078 0.0158 0.0181
Echinococcus granulosus raf serine:threonine protein kinase 0.0084 0.0216 0.0456
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Loa Loa (eye worm) hypothetical protein 0.0203 0.1398 0.1398
Brugia malayi cyclin-dependent kinase 7 homolog 0.0114 0.0518 0.0518
Loa Loa (eye worm) hypothetical protein 0.0145 0.0826 0.0826
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0126 0.0636 0.0636
Trichomonas vaginalis CMGC family protein kinase 0.0126 0.064 0.5006
Loa Loa (eye worm) hypothetical protein 0.0128 0.0655 0.0655
Echinococcus granulosus protein kinase 0.0067 0.0045 0.0095
Echinococcus granulosus protein tyrosine kinase 0.0354 0.2901 0.6116
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Echinococcus granulosus dual specificity 0.022 0.1575 0.332
Loa Loa (eye worm) TK/INSR protein kinase 0.0215 0.1519 0.1519
Schistosoma mansoni tyrosine kinase 0.0067 0.0047 0.0117
Echinococcus multilocularis FL cytokine receptor 0.0067 0.0045 0.0051
Echinococcus granulosus retinal guanylyl cyclase 2 0.0067 0.0045 0.0095
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0067 0.0045 0.0045
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0226 0.163 0.163
Echinococcus multilocularis integrin linked protein kinase 0.0067 0.0045 0.0051
Loa Loa (eye worm) TK protein kinase 0.0337 0.2736 0.2736
Echinococcus multilocularis nostrin 0.0128 0.0655 0.0747
Schistosoma mansoni SH2A 0.0137 0.0744 0.1856
Brugia malayi RhoGAP domain containing protein 0.0154 0.0915 0.0915
Schistosoma mansoni dynamin-associated protein 0.013 0.0673 0.1678
Onchocerca volvulus 0.0203 0.1406 0.1406
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0186 0.1234 0.7774
Entamoeba histolytica tyrosine kinase, putative 0.0067 0.0045 0.0005
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0186 0.1234 0.1234
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0109 0.0463 0.0977
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0465 0.4007 0.4574
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0067 0.0045 0.0051
Echinococcus granulosus kinase suppressor of Ras 1 0.0067 0.0045 0.0095
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0113 0.0509 0.0509
Echinococcus granulosus src region 0.0128 0.0655 0.138
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0186 0.1238 0.2611
Loa Loa (eye worm) hypothetical protein 0.0203 0.1403 0.1403
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0063 0.0012 0.0026
Entamoeba histolytica protein kinase, putative 0.0067 0.0045 0.0005
Schistosoma mansoni tyrosine kinase 0.0331 0.2678 0.6682
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0067 0.0045 0.0051
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0208 0.1453 0.3063
Entamoeba histolytica serine/threonine kinase, putative 0.0067 0.0045 0.0005
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0066 0.0044 0.0044
Echinococcus multilocularis hematopoietic lineage cell specific protein 0.0128 0.0655 0.0747
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0153 0.0902 0.103
Entamoeba histolytica protein kinase, putative 0.0126 0.064 0.3892
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0075 0.0129 0.0148
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0216 0.054
Trypanosoma cruzi protein kinase, putative 0.0067 0.0045 0.0005
Brugia malayi Tyrosine-protein kinase abl-1 0.0145 0.0828 0.0828
Schistosoma mansoni suppressor of cytokine signaling 0.0137 0.0744 0.1856
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.1695 0.423
Trichomonas vaginalis TK family protein kinase 0.0067 0.0045 0.0007
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0067 0.0045 0.0045
Brugia malayi P38 map kinase family protein 2 0.0161 0.0983 0.0983
Plasmodium falciparum protein serine/threonine kinase-1 0.0155 0.0922 1
Schistosoma mansoni cell adhesion molecule 0.0063 0.0012 0.0031
Loa Loa (eye worm) TK/FER protein kinase 0.0067 0.0045 0.0045
Brugia malayi Variant SH3 domain containing protein 0.0154 0.0915 0.0915
Echinococcus multilocularis TGF beta receptor type 1 0.0099 0.037 0.0422
Entamoeba histolytica hypothetical protein 0.0067 0.005 0.0041
Schistosoma mansoni nephrin 0.0142 0.08 0.1996
Loa Loa (eye worm) TK/FER protein kinase 0.0203 0.1406 0.1406
Brugia malayi SH2 domain containing protein 0.0137 0.0744 0.0744
Loa Loa (eye worm) hypothetical protein 0.0255 0.1918 0.1918
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Entamoeba histolytica hypothetical protein 0.0128 0.0655 0.3989
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0067 0.0045 0.0045
Echinococcus granulosus tyrosine protein kinase shark 0.0203 0.1406 0.2964
Schistosoma mansoni tyrosine kinase 0.0067 0.0047 0.0117
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0137 0.0744 0.1568
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0067 0.0045 0.0045
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0126 0.064 0.3892
Loa Loa (eye worm) AUR protein kinase 0.0145 0.083 0.083
Schistosoma mansoni serine/threonine RGC 0.0067 0.0045 0.0112
Loa Loa (eye worm) AGC/PKA protein kinase 0.0109 0.0463 0.0463
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0155 0.0922 0.5733
Brugia malayi hypothetical protein 0.0115 0.0524 0.0524
Schistosoma mansoni tensin 0.0137 0.0744 0.1856
Echinococcus multilocularis 0.0137 0.0744 0.0849
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0087 0.0251 0.0251
Entamoeba histolytica ankyrin repeat protein 0.0067 0.0045 0.0005
Entamoeba histolytica tyrosine kinase, putative 0.0067 0.0045 0.0005
Brugia malayi SH3 domain containing protein 0.0128 0.0655 0.0655
Schistosoma mansoni tyrosine kinase 0.0067 0.0045 0.0112
Loa Loa (eye worm) hypothetical protein 0.0128 0.0655 0.0655
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0137 0.0744 0.0744
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0337 0.2736 0.3123
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Onchocerca volvulus 0.0067 0.0045 0.0045
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0067 0.0045 0.0045
Echinococcus granulosus tyrosine protein kinase Srms 0.0203 0.1406 0.2964
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0087 0.0251 0.0251
Echinococcus multilocularis epidermal growth factor receptor kinase 0.0128 0.0655 0.0747
Entamoeba histolytica protein kinase, putative 0.0067 0.0045 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Onchocerca volvulus 0.0067 0.0045 0.0045
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Echinococcus granulosus signal transduction protein lnk realted 0.0137 0.0744 0.1568
Schistosoma mansoni Dab2-interacting protein-like 0.0128 0.0655 0.1634
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0465 0.4007 0.8449
Loa Loa (eye worm) TK/FER protein kinase 0.0203 0.1406 0.1406
Plasmodium vivax serine/threonine kinase-1, putative 0.0155 0.0922 1
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0154 0.0915 0.193
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0179 0.1164 0.2453
Trypanosoma brucei aurora B kinase 0.0145 0.083 0.5132
Loa Loa (eye worm) TK/EGFR protein kinase 0.0133 0.0709 0.0709
Echinococcus granulosus Immunoglobulin 0.0098 0.036 0.0759
Echinococcus multilocularis tyrosine protein kinase csk 0.0067 0.0045 0.0051
Onchocerca volvulus 0.0512 0.448 0.448
Echinococcus multilocularis aurora kinase A 0.0145 0.083 0.0947
Loa Loa (eye worm) hypothetical protein 0.0098 0.036 0.036
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0067 0.0045 0.0051
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0465 0.4007 0.4574
Entamoeba histolytica ankyrin repeat protein 0.0067 0.0045 0.0005
Entamoeba histolytica tyrosine kinase, putative 0.0067 0.0045 0.0005
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0145 0.083 0.5132
Echinococcus granulosus epidermal growth factor receptor kinase 0.0128 0.0655 0.138
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0132 0.0693 0.1462
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0063 0.0012 0.0031
Schistosoma mansoni protein kinase 0.0067 0.0045 0.0112
Schistosoma mansoni tyrosine kinase 0.0133 0.0709 0.1769
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0068 0.0063 0.0072
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.083 0.207
Entamoeba histolytica unconventional myosin IB 0.0128 0.0655 0.3989
Brugia malayi Protein kinase domain containing protein 0.0084 0.0222 0.0222
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Brugia malayi Stress-activated protein kinase jnk-1 0.028 0.217 0.217
Brugia malayi Immunoglobulin I-set domain containing protein 0.0207 0.144 0.144
Onchocerca volvulus Putative cortactin 0.0128 0.0655 0.0655
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0084 0.0222 0.0222
Echinococcus multilocularis cyclin dependent kinase 9 0.0069 0.0069 0.0079
Echinococcus multilocularis tyrosine protein kinase pr2 0.0067 0.0045 0.0051
Schistosoma mansoni tyrosine kinase 0.0465 0.4007 1
Toxoplasma gondii AGC kinase 0.0109 0.0463 0.4777
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0301 0.075
Loa Loa (eye worm) hypothetical protein 0.0137 0.0744 0.0744
Plasmodium vivax tyrosine kinase-like protein, putative 0.0067 0.0045 0.0009
Loa Loa (eye worm) gastrulation defective protein 1 0.0149 0.0862 0.0862
Echinococcus multilocularis epidermal growth factor receptor 0.0133 0.0709 0.0809
Schistosoma mansoni run and tbc1 domain containing 0.0128 0.0655 0.1634
Echinococcus granulosus receptor type guanylyl cyclase 0.0067 0.0045 0.0095
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Loa Loa (eye worm) serine/threonine protein kinase 0.0067 0.0045 0.0045
Brugia malayi SRC-1 0.0465 0.4007 0.4007
Loa Loa (eye worm) hypothetical protein 0.0137 0.0744 0.0744
Brugia malayi hypothetical protein 0.0069 0.0074 0.0074
Onchocerca volvulus 0.0067 0.0045 0.0045
Echinococcus multilocularis tensin 0.0137 0.0744 0.0849
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0161 0.0983 0.6137
Entamoeba histolytica tyrosine kinase, putative 0.0067 0.0045 0.0005
Echinococcus multilocularis protein kinase c epsilon type 0.0063 0.0008 0.0009
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0117 0.0548 0.329
Schistosoma mansoni protein kinase 0.0186 0.1238 0.309
Loa Loa (eye worm) hypothetical protein 0.0137 0.0744 0.0744
Trichomonas vaginalis CAMK family protein kinase 0.0067 0.0045 0.0007
Onchocerca volvulus 0.0126 0.064 0.064
Trichomonas vaginalis AGC family protein kinase 0.0145 0.083 0.6601
Loa Loa (eye worm) RGC/RGC protein kinase 0.0067 0.0045 0.0045
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0164 0.101 0.101
Onchocerca volvulus 0.0137 0.0744 0.0744
Loa Loa (eye worm) TK/ACK protein kinase 0.0067 0.0045 0.0045
Entamoeba histolytica receptor protein kinase, putative 0.0067 0.0045 0.0005
Entamoeba histolytica hypothetical protein 0.0132 0.0693 0.4242
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0109 0.0463 0.4777
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0067 0.0045 0.0005
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0155 0.0921 0.5728
Echinococcus multilocularis mitogen activated protein kinase 11 0.0161 0.0983 0.1123
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.022 0.1575 1
Schistosoma mansoni serine/threonine protein kinase 0.0212 0.1494 0.3727
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0465 0.4007 0.4574
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0153 0.0902 0.0902
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0902 0.2251
Echinococcus granulosus protein kinase shaggy 0.0126 0.064 0.1349
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0098 0.036 0.0898
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0208 0.1453 0.1453
Loa Loa (eye worm) SRC-1 0.0465 0.4007 0.4007
Entamoeba histolytica protein kinase, putative 0.0067 0.0045 0.0005
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Brugia malayi Tensin 0.0137 0.0744 0.0744
Entamoeba histolytica tyrosine kinase, putative 0.0067 0.0045 0.0005
Echinococcus granulosus cyclin dependent kinase 1 0.0066 0.0044 0.0093
Schistosoma mansoni cell adhesion molecule 0.0134 0.0713 0.1779
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0132 0.0693 0.0791
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0208 0.1453 0.1658
Schistosoma mansoni GTPase activating protein 0.0137 0.0744 0.1856
Echinococcus multilocularis c Jun NH2 terminal kinase 0.028 0.217 0.2477
Entamoeba histolytica protein kinase, putative 0.02 0.1375 0.8692
Brugia malayi Immunoglobulin I-set domain containing protein 0.0115 0.0524 0.0524
Echinococcus granulosus nostrin 0.0128 0.0655 0.138
Leishmania major protein kinase A catalytic subunit 0.0109 0.0463 0.2739
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0465 0.4007 0.4574
Loa Loa (eye worm) hypothetical protein 0.0137 0.0744 0.0744
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0063 0.0012 0.0014
Entamoeba histolytica tyrosin kinase, putative 0.0067 0.0045 0.0005
Brugia malayi Variant SH3 domain containing protein 0.013 0.0673 0.0673
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0084 0.0222 0.1162
Entamoeba histolytica tyrosin kinase, putative 0.0075 0.0126 0.0533
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0149 0.0865 0.0865
Schistosoma mansoni cell adhesion molecule 0.0063 0.0012 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0463 0.1156
Trichomonas vaginalis TKL family protein kinase 0.0067 0.0045 0.0007
Brugia malayi C1-like domain containing protein 0.0104 0.0422 0.0422
Entamoeba histolytica protein kinase domain containing protein 0.0067 0.0045 0.0005
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0069 0.0069 0.0069
Schistosoma mansoni tyrosine kinase 0.0067 0.0045 0.0112
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0155 0.0922 1
Echinococcus multilocularis tyrosine protein kinase shark 0.0203 0.1406 0.1605
Brugia malayi Src substrate cortactin 0.0128 0.0655 0.0655
Schistosoma mansoni protein kinase 0.0201 0.1382 0.3449
Loa Loa (eye worm) hypothetical protein 0.0073 0.0104 0.0104
Trypanosoma brucei conserved protein 0.0128 0.0655 0.3989
Echinococcus granulosus SHC transforming protein 3 0.0137 0.0744 0.1568
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0465 0.4007 0.4574
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0231 0.1683 0.3548
Brugia malayi Variant SH3 domain containing protein 0.0141 0.0783 0.0783
Schistosoma mansoni hypothetical protein 0.0128 0.0655 0.1634
Brugia malayi Protein kinase domain containing protein 0.0067 0.0045 0.0045
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0155 0.0922 0.5733
Brugia malayi protein-tyrosine kinase 0.0128 0.0655 0.0655
Schistosoma mansoni sorbin 0.0128 0.0655 0.1634
Entamoeba histolytica SH2 domain containing protein 0.0137 0.0744 0.4572
Loa Loa (eye worm) hypothetical protein 0.0128 0.0656 0.0656
Brugia malayi Myosin tail family protein 0.0128 0.0655 0.0655
Schistosoma mansoni tyrosine kinase 0.0465 0.4007 1
Loa Loa (eye worm) hypothetical protein 0.0141 0.0783 0.0783
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0067 0.0045 0.0007
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0203 0.1406 0.8898
Entamoeba histolytica protein kinase, putative 0.0067 0.0045 0.0005
Leishmania major protein kinase A catalytic subunit isoform 2 0.0109 0.0463 0.2739
Schistosoma mansoni tyrosine kinase 0.0067 0.0045 0.0112
Loa Loa (eye worm) hypothetical protein 0.0091 0.0284 0.0284
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0099 0.037 0.0422
Onchocerca volvulus 0.0203 0.1406 0.1406
Plasmodium vivax glycogen synthase kinase 3, putative 0.0126 0.064 0.6789
Entamoeba histolytica hypothetical protein 0.0128 0.0655 0.3989
Entamoeba histolytica hypothetical protein 0.0128 0.0655 0.3989
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0091 0.0286 0.0327
Brugia malayi SH2 domain containing protein 0.0137 0.0744 0.0744
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0137 0.0744 0.1856
Loa Loa (eye worm) hypothetical protein 0.0069 0.0074 0.0074
Echinococcus granulosus tyrosine kinase 0.0337 0.2736 0.5768
Entamoeba histolytica protein kinase domain containing protein 0.0084 0.0222 0.1162
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0067 0.0045 0.0005
Entamoeba histolytica hypothetical protein 0.0067 0.0045 0.0005
Giardia lamblia Kinase, CMGC GSK 0.0126 0.064 0.5006
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0155 0.0922 0.5733
Echinococcus multilocularis tyrosine protein kinase 0.0067 0.0045 0.0051
Plasmodium falciparum protein kinase, putative 0.0067 0.0045 0.0009
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0137 0.0744 0.0849
Echinococcus multilocularis tyrosine protein kinase csk 0.0067 0.0045 0.0051
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0331 0.2678 0.6682
Loa Loa (eye worm) hypothetical protein 0.0551 0.4864 0.4864
Trypanosoma brucei protein kinase, putative 0.0084 0.0222 0.1162
Echinococcus multilocularis heat shock protein 70 0.0067 0.0045 0.0051

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 1.7 uM Inhibition against the proliferation of L1210 leukemia ChEMBL. 3656351
IC50 (functional) = 1.7 uM Inhibition against the proliferation of L1210 leukemia ChEMBL. 3656351
MI (functional) = 7 uM Mitotic index of the compound(MI). ChEMBL. 3656351
MI (functional) = 7 uM Mitotic index of the compound(MI). ChEMBL. 3656351

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Mus musculus ChEMBL23 3656351

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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