Detailed information for compound 689561

Basic information

Technical information
  • TDR Targets ID: 689561
  • Name: N-(2,5-dimethoxyphenyl)-2-[2-(2-methoxyethyl) -1-oxoisoquinolin-5-yl]oxyacetamide
  • MW: 412.436 | Formula: C22H24N2O6
  • H donors: 1 H acceptors: 2 LogP: 2.19 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: COCCn1ccc2c(c1=O)cccc2OCC(=O)Nc1cc(OC)ccc1OC
  • InChi: 1S/C22H24N2O6/c1-27-12-11-24-10-9-16-17(22(24)26)5-4-6-19(16)30-14-21(25)23-18-13-15(28-2)7-8-20(18)29-3/h4-10,13H,11-12,14H2,1-3H3,(H,23,25)
  • InChiKey: NAMXJOGZTGGYGC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(2,5-dimethoxyphenyl)-2-[[2-(2-methoxyethyl)-1-oxo-5-isoquinolyl]oxy]acetamide
  • N-(2,5-dimethoxyphenyl)-2-[[1-keto-2-(2-methoxyethyl)-5-isoquinolyl]oxy]acetamide
  • N-(2,5-dimethoxyphenyl)-2-[2-(2-methoxyethyl)-1-oxo-isoquinolin-5-yl]oxy-ethanamide
  • ZINC04584298

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni protein phosphatase 2C 0.0025 0.0055 0.0075
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0045 0.0179 0.0267
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0045 0.0179 0.0272
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0092 0.047 0.0461
Loa Loa (eye worm) hypothetical protein 0.0103 0.054 0.0536
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0179 0.017
Loa Loa (eye worm) AGC/PKN protein kinase 0.0544 0.3268 0.3265
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0045 0.0179 0.017
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0544 0.3268 0.4872
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0045 0.0179 0.1014
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0022 0.0038 0.0132
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Loa Loa (eye worm) hypothetical protein 0.0021 0.0035 0.0031
Onchocerca volvulus Glucosylceramidase homolog 0.0164 0.092 0.6105
Plasmodium vivax acetyl-CoA synthetase, putative 0.0022 0.0038 0.0029
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Echinococcus multilocularis lysine specific demethylase 5A 0.0092 0.0474 0.0707
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0031 0.0027
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0021 0.0035 0.0031
Brugia malayi Protein kinase domain containing protein 0.0544 0.3268 0.3265
Onchocerca volvulus 0.0026 0.0061 0.0202
Brugia malayi glutaminase DH11.1 0.03 0.1761 0.1757
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0031 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0324 0.0315
Schistosoma mansoni vav2 0.0045 0.0179 0.0261
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0092 0.047 0.0694
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Loa Loa (eye worm) hypothetical protein 0.0021 0.0031 0.0027
Onchocerca volvulus 0.0039 0.0144 0.0773
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.1055 0.643 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0038 0.0081
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0144 0.0208
Onchocerca volvulus 0.0039 0.0144 0.0773
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0025 0.0055 0.0075
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.005 0.0069
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0031 0.0027
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0092 0.047 0.0461
Toxoplasma gondii hypothetical protein 0.0045 0.0179 0.018
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0275 0.0271
Echinococcus multilocularis geminin 0.0536 0.3218 0.4798
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0031 0.0047
Trypanosoma cruzi PH domain containing protein, putative 0.0045 0.0179 0.0253
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0031 0.0027
Echinococcus granulosus Oxysterol binding protein 11 0.0045 0.0179 0.0267
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0208 0.0199
Echinococcus multilocularis neuropeptide s receptor 0.0451 0.2694 0.4017
Schistosoma mansoni hypothetical protein 0.0045 0.0179 0.0261
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.1587 0.9723 0.9723
Mycobacterium tuberculosis Possible penicillin-binding protein 0.025 0.1447 1
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0154 0.0229
Onchocerca volvulus 0.0045 0.0179 0.1014
Mycobacterium tuberculosis Conserved protein 0.0039 0.0144 0.0875
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0092 0.047 0.0466
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.092 0.0911
Schistosoma mansoni serine/threonine protein kinase 0.0544 0.3268 0.4869
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0056 0.0252 0.0242
Brugia malayi Latrophilin receptor protein 2 0.0148 0.0816 0.0812
Schistosoma mansoni cpg binding protein 0.0062 0.0288 0.0423
Onchocerca volvulus outspread protein homolog 0.0045 0.0179 0.1014
Onchocerca volvulus 0.0045 0.0179 0.1014
Onchocerca volvulus Alhambra homolog 0.0029 0.0083 0.0353
Brugia malayi Variant SH3 domain containing protein 0.0045 0.0179 0.0175
Trichomonas vaginalis AGC family protein kinase 0.1632 1 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0009 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.092 0.0911
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0544 0.3268 0.4872
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.049 0.0731
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0031 0.0027
Onchocerca volvulus Protein melted homolog 0.0045 0.0179 0.1014
Schistosoma mansoni acetyl-CoA synthetase 0.0022 0.0038 0.005
Echinococcus granulosus oxysterol binding protein 9 0.0045 0.0179 0.0267
Trypanosoma cruzi NIMA-related kinase, putative 0.0056 0.0252 0.0362
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0467 0.2789 0.2786
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0076 0.0372 0.0367
Loa Loa (eye worm) hypothetical protein 0.0033 0.0109 0.0104
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0045 0.0179 0.0175
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0045 0.0179 0.017
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0031 0.0041
Plasmodium falciparum acyl-CoA synthetase 0.0056 0.0247 0.0378
Echinococcus granulosus serine:threonine protein kinase N2 0.0544 0.3268 0.4872
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Entamoeba histolytica hypothetical protein 0.0045 0.0179 0.017
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0038 0.0033
Loa Loa (eye worm) hypothetical protein 0.0039 0.0144 0.014
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0179 0.017
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0189 0.0281
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0038 0.0081
Treponema pallidum bacterioferrin (TpF1) 0.002 0.0024 0.5
Loa Loa (eye worm) hypothetical protein 0.0544 0.3268 0.3265
Entamoeba histolytica ARF GTPase activating protein, putative 0.0045 0.0179 0.017
Loa Loa (eye worm) uncoordinated protein 104 0.0045 0.0179 0.0175
Echinococcus multilocularis metabotropic glutamate receptor 2 0.007 0.0336 0.0501
Toxoplasma gondii phosphatidylinositol transfer protein 0.0045 0.0179 0.018
Brugia malayi jmjC domain containing protein 0.0025 0.0055 0.005
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0228 0.1467
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0045 0.0179 0.0267
Trichomonas vaginalis set domain proteins, putative 0.0256 0.1486 0.1478
Onchocerca volvulus Putative zinc finger protein 0.0045 0.0179 0.1014
Trypanosoma cruzi hypothetical protein 0.0045 0.0179 0.0253
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0031 0.0047
Brugia malayi PH domain containing protein 0.0045 0.0179 0.0175
Brugia malayi hypothetical protein 0.0045 0.0179 0.0175
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0083 0.0081
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0031 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.047 0.0461
Entamoeba histolytica protein kinase, putative 0.0056 0.0252 0.0242
Schistosoma mansoni hypothetical protein 0.0536 0.3218 0.4795
Entamoeba histolytica acyl-coA synthetase, putative 0.0075 0.0364 0.0355
Echinococcus multilocularis oxysterol binding protein 1 0.0045 0.0179 0.0267
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0109 0.0162
Echinococcus multilocularis serine:threonine protein kinase 38 0.0544 0.3268 0.4872
Toxoplasma gondii target of rapamycin (TOR), putative 0.0068 0.0324 0.0329
Trichomonas vaginalis chaperonin, putative 0.0024 0.005 0.0041
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0144 0.0875
Onchocerca volvulus 0.0022 0.0038 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0324 0.0315
Loa Loa (eye worm) hypothetical protein 0.0467 0.2789 0.2786
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0022 0.0038 0.0034
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0544 0.3268 0.4872
Echinococcus multilocularis microtubule associated protein 2 0.067 0.4046 0.6032
Brugia malayi mbt repeat family protein 0.0046 0.0189 0.0184
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0055 0.0067
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0045 0.0179 0.0253
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0045 0.0179 0.0267
Brugia malayi Calcitonin receptor-like protein seb-1 0.0467 0.2789 0.2786
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0045 0.0179 0.0267
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0148 0.0816 0.1216
Loa Loa (eye worm) hypothetical protein 0.0021 0.0031 0.0027
Echinococcus granulosus oxysterol binding protein 1 0.0045 0.0179 0.0267
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0083 0.0099
Entamoeba histolytica protein kinase, putative 0.1632 1 1
Loa Loa (eye worm) hypothetical protein 0.0148 0.0816 0.0812
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0056 0.0252 0.0242
Echinococcus granulosus Rho GTPase activating protein 24 0.0045 0.0179 0.0267
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0017 0.0009 0.0014
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0031 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0179 0.017
Brugia malayi MH2 domain containing protein 0.0116 0.0619 0.0615
Leishmania major protein kinase, putative 0.0056 0.0252 0.1095
Trypanosoma cruzi PH domain containing protein, putative 0.0045 0.0179 0.0253
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0031 0.0047
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0131 0.0181
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0255 0.1482 0.221
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0031 0.0041
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0022 0.0038 0.0132
Echinococcus multilocularis serine threonine protein kinase 0.0544 0.3268 0.4872
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0031 0.0027
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0544 0.3268 0.4872
Echinococcus granulosus cpg binding protein 0.0062 0.0288 0.0429
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0544 0.3268 0.4872
Echinococcus multilocularis phd:f box containing protein 0.0025 0.0055 0.0081
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0038 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0179 0.017
Brugia malayi Uncoordinated protein 104 0.0045 0.0179 0.0175
Loa Loa (eye worm) glutamate receptor 0.0084 0.042 0.0416
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0038 0.0033
Echinococcus multilocularis Ras associated and pleckstrin y 0.0045 0.0179 0.0267
Onchocerca volvulus 0.0151 0.0834 0.5517
Schistosoma mansoni goodpasture antigen-binding protein 0.0045 0.0179 0.0261
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0144 0.0875
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0036 0.0127 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0092 0.0083
Echinococcus granulosus neuropeptide s receptor 0.0451 0.2694 0.4017
Brugia malayi nuclear receptor NHR-88 0.0021 0.0031 0.0027
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.008 0.0076
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0154 0.0229
Schistosoma mansoni fkbp-rapamycin associated protein 0.0017 0.0009 0.0008
Brugia malayi MAX-1A 0.0045 0.0179 0.0175
Trypanosoma brucei pyruvate kinase 1, putative 0.0037 0.0131 0.0121
Entamoeba histolytica protein kinase, putative 0.1587 0.9723 0.9723
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0036 0.0127 0.0122
Echinococcus granulosus lysine specific demethylase 5A 0.0096 0.0495 0.0738
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0092 0.0083
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.049 0.0725
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0083 0.0123
Leishmania major hypothetical protein, conserved 0.0025 0.0055 0.0222
Loa Loa (eye worm) AGC/NDR protein kinase 0.0544 0.3268 0.3265
Trichomonas vaginalis AGC family protein kinase 0.1632 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0544 0.3268 0.4869
Echinococcus multilocularis rac serine:threonine kinase 0.11 0.6707 1
Echinococcus granulosus Pleckstrin y 0.0045 0.0179 0.0267
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0153 0.0847 0.1263
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0045 0.0179 0.0267
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0544 0.3268 0.3265
Loa Loa (eye worm) hypothetical protein 0.0151 0.0834 0.083
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0122 0.0176
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0144 0.0875
Schistosoma mansoni myotubularin-related protein 0.0045 0.0179 0.0261
Brugia malayi jmjC domain containing protein 0.0025 0.0055 0.005
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0031 0.0027
Loa Loa (eye worm) AGC/AKT protein kinase 0.1632 1 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0055 0.005
Loa Loa (eye worm) hypothetical protein 0.0319 0.1876 0.1872
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0092 0.047 0.0461
Trypanosoma brucei rac serine-threonine kinase, putative 0.1632 1 1
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Mycobacterium ulcerans acyl-CoA synthetase 0.0075 0.0364 0.196
Trichomonas vaginalis alpha chimerin, putative 0.0045 0.0179 0.017
Trypanosoma cruzi PH domain containing protein, putative 0.0045 0.0179 0.0253
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Mycobacterium ulcerans hypothetical protein 0.0075 0.0364 0.196
Entamoeba histolytica PH domain containing protein kinase, putative 0.0056 0.0252 0.0242
Echinococcus multilocularis pyruvate kinase 0.0019 0.0019 0.0029
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0031 0.0092 0.0131
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0031 0.0027
Brugia malayi jmjC domain containing protein 0.0096 0.0495 0.0491
Loa Loa (eye worm) glutamate receptor 0.0033 0.0106 0.0102
Entamoeba histolytica protein kinase, putative 0.0056 0.0252 0.0242
Leishmania major serine/threonine-protein kinase a, putative 0.0056 0.0252 0.1095
Echinococcus multilocularis pyruvate kinase 0.0037 0.0131 0.0195
Brugia malayi Pre-SET motif family protein 0.0225 0.1295 0.1291
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0075 0.0364 0.196
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0131 0.0126
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0056 0.0252 0.0362
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0043 0.0171 0.0161
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0059 0.0082
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0038 0.0028
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0075 0.0364 0.196
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0031 0.0047
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0024 0.005 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Trypanosoma cruzi PAB1-binding protein , putative 0.0381 0.2263 0.3364
Brugia malayi PHD-finger family protein 0.0029 0.0083 0.0078
Onchocerca volvulus 0.0045 0.0179 0.1014
Trichomonas vaginalis glutaminase, putative 0.03 0.1761 0.1753
Echinococcus granulosus cytohesin 1 0.0045 0.0179 0.0267
Brugia malayi PH domain containing protein 0.0045 0.0179 0.0175
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0025 0.0055 0.0052
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.1055 0.643 0.9587
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0056 0.0252 0.0362
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0147 0.0213
Brugia malayi beta-lactamase family protein 0.0039 0.0144 0.014
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1453 0.1445
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0209 0.0199
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0544 0.3268 0.3265
Plasmodium falciparum oxysterol-binding protein, putative 0.0045 0.0179 0.0272
Toxoplasma gondii LsmAD domain-containing protein 0.0381 0.2263 0.2324
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Toxoplasma gondii Oxysterol-binding protein 0.0045 0.0179 0.018
Echinococcus multilocularis expressed protein 0.002 0.0024 0.0035
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.002 0.0024 0.0034
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0144 0.0208
Brugia malayi latrophilin 2 splice variant baaae 0.0319 0.1876 0.1872
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0179 0.017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0109 0.0156
Echinococcus granulosus serine protein kinase ATM 0.0017 0.0009 0.0014
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0148 0.0816 0.1216
Schistosoma mansoni hypothetical protein 0.0045 0.0179 0.0261
Echinococcus granulosus nervana 2 0.1043 0.6358 0.9479
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0324 0.0315
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0075 0.0364 0.2417
Mycobacterium ulcerans acetyl-CoA synthetase 0.0022 0.0038 0.0081
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0619 0.0615
Echinococcus granulosus metabotropic glutamate receptor 2 0.007 0.0336 0.0501
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.1055 0.643 0.9587
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0189 0.1079
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0045 0.0179 0.0267
Echinococcus granulosus Pleckstrin y 0.0045 0.0179 0.0267
Loa Loa (eye worm) hypothetical protein 0.0021 0.0031 0.0027
Trichomonas vaginalis AGC family protein kinase 0.0544 0.3268 0.3261
Trypanosoma cruzi NIMA-related kinase, putative 0.0056 0.0252 0.0362
Brugia malayi Cadps2 protein 0.0045 0.0179 0.0175
Onchocerca volvulus 0.0039 0.0144 0.0773
Loa Loa (eye worm) glutaminase 2 0.03 0.1761 0.1757
Entamoeba histolytica PH domain containing protein kinase, putative 0.11 0.6707 0.6704
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0144 0.0692
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0179 0.017
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0031 0.0047
Brugia malayi jmjC domain containing protein 0.0025 0.0055 0.005
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.049 0.0731
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0057
Plasmodium vivax JmjC domain containing protein 0.0025 0.0055 0.0055
Brugia malayi AMP-binding enzyme family protein 0.0075 0.0364 0.036
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0025 0.0055 0.0045
Trypanosoma cruzi hypothetical protein 0.0045 0.0179 0.0253
Loa Loa (eye worm) hypothetical protein 0.0039 0.0144 0.014
Trypanosoma cruzi hypothetical protein 0.0045 0.0179 0.0253
Giardia lamblia Pyruvate kinase 0.0037 0.0131 0.0174
Trichomonas vaginalis protein transport protein sec7, putative 0.0045 0.0179 0.017
Echinococcus multilocularis calcium dependent secretion activator 1 0.0045 0.0179 0.0267
Echinococcus multilocularis JmjC domain containing protein 4 0.0025 0.0055 0.0081
Schistosoma mansoni phosphatidylserine receptor 0.0025 0.0055 0.0075
Plasmodium vivax acyl-CoA synthetase, putative 0.0056 0.0247 0.0356
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0031 0.0092 0.0124
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0045 0.0179 0.017
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0022 0.0038 0.0052
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0131 0.0681
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0241 0.0232
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0045 0.0179 0.017
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0038 0.0042
Leishmania major hypothetical protein, conserved 0.0045 0.0179 0.0774
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0109 0.0156
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Schistosoma mansoni ferritin 0.002 0.0024 0.0029
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0031 0.0041
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0024 0.005 0.0061
Trypanosoma cruzi rac serine-threonine kinase, putative 0.11 0.6707 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0228 0.1467
Echinococcus multilocularis serine:threonine protein kinase N2 0.0544 0.3268 0.4872
Brugia malayi beta-lactamase family protein 0.0039 0.0144 0.014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0241 0.0232
Echinococcus granulosus NDR protein kinase 0.0544 0.3268 0.4872
Brugia malayi mbt repeat family protein 0.0046 0.0189 0.0184
Brugia malayi Hr1 repeat family protein 0.0544 0.3268 0.3265
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0055 0.005
Plasmodium falciparum T-complex protein 1 subunit beta 0.0024 0.005 0.0072
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0144 0.014
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Entamoeba histolytica protein kinase, putative 0.1632 1 1
Echinococcus granulosus dynamin 1 0.0045 0.0179 0.0267
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0031 0.0027
Echinococcus granulosus geminin 0.0536 0.3218 0.4798
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0092 0.047 0.0687
Trichomonas vaginalis centaurin beta, putative 0.0045 0.0179 0.017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0228 0.1467
Schistosoma mansoni hypothetical protein 0.0045 0.0179 0.0261
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0179 0.017
Trypanosoma cruzi hypothetical protein 0.0045 0.0179 0.0253
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0045 0.0179 0.0267
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0131 0.0681
Brugia malayi Dynamin 0.0045 0.0179 0.0175
Brugia malayi Plekhf2 protein 0.0045 0.0179 0.0175
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0031 0.0047
Schistosoma mansoni atypical protein kinase C 0.0544 0.3268 0.4869
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0144 0.0201
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0148 0.0816 0.1216
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0255 0.1482 0.2205
Entamoeba histolytica hypothetical protein 0.0045 0.0179 0.017
Toxoplasma gondii AtPH1 family protein 0.0045 0.0179 0.018
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0544 0.3268 0.4872
Leishmania major protein kinase, putative 0.0056 0.0252 0.1095
Entamoeba histolytica PH domain containing protein 0.0045 0.0179 0.017
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0031 0.0027
Echinococcus multilocularis peregrin 0.0029 0.0083 0.0123
Loa Loa (eye worm) hypothetical protein 0.0381 0.2263 0.2259
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0022 0.0038 0.0081
Brugia malayi Pyruvate kinase, M2 isozyme 0.0037 0.0131 0.0126
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0144 0.014
Onchocerca volvulus 0.0059 0.0267 0.1617
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0045 0.0179 0.0175
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0112 0.0102
Echinococcus multilocularis serine:threonine protein kinase N2 0.0544 0.3268 0.4872
Echinococcus multilocularis actin binding protein anillin 0.0045 0.0179 0.0267
Mycobacterium ulcerans glutaminase 0.03 0.1761 1
Echinococcus multilocularis dnaJ subfamily B 0.043 0.2561 0.3818
Loa Loa (eye worm) Plekhf2 protein 0.0045 0.0179 0.0175
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.047 0.0461
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0045 0.0179 0.0175
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0038 0.0033
Brugia malayi Metabotropic glutamate receptor precursor. 0.0084 0.042 0.0416
Brugia malayi nuclear hormone receptor 0.0021 0.0031 0.0027
Brugia malayi PH domain containing protein 0.0045 0.0179 0.0175
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0144 0.0135
Echinococcus multilocularis pyruvate kinase 0.0037 0.0131 0.0195
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0038 0.0081
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0056 0.0252 0.1095
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0038 0.0132
Loa Loa (eye worm) jmjC domain-containing protein 0.0096 0.0495 0.0491
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0056 0.0247 0.1599
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0122 0.0182
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0144 0.0875
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0092 0.047 0.2061
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0045 0.0179 0.0261
Trypanosoma cruzi hypothetical protein 0.0045 0.0179 0.0253
Plasmodium falciparum phd finger protein, putative 0.0029 0.0083 0.0122
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0031 0.0047
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0045 0.0179 0.017
Trichomonas vaginalis AGC family protein kinase 0.1632 1 1
Loa Loa (eye worm) oxysterol binding protein 0.0045 0.0179 0.0175
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0031 0.0027
Echinococcus multilocularis lysine specific demethylase 6a 0.0025 0.0055 0.0081
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0228 0.1467
Entamoeba histolytica protein kinase, putative 0.0544 0.3268 0.3261
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0092 0.0083
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0189 0.0281
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0028 0.0075 0.0112
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0022 0.0038 0.0081
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0144 0.0215
Loa Loa (eye worm) hypothetical protein 0.0025 0.0055 0.005
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0045 0.0179 0.017
Plasmodium falciparum pyruvate kinase 2 0.0019 0.0019 0.0023
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0045 0.0179 0.0267
Brugia malayi TBC domain containing protein 0.0045 0.0179 0.0175
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0038 0.0081
Plasmodium falciparum ataxin-2 like protein, putative 0.0381 0.2263 0.3515
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0045 0.0179 0.0267
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0031 0.0027
Onchocerca volvulus 0.0022 0.0038 0.0043
Mycobacterium ulcerans acyl-CoA synthetase 0.0075 0.0364 0.196
Brugia malayi jmjC domain containing protein 0.0153 0.0847 0.0843
Trichomonas vaginalis AGC family protein kinase 0.0544 0.3268 0.3261
Loa Loa (eye worm) PH domain-containing protein 0.0045 0.0179 0.0175
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0045 0.0179 0.0253
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0022 0.0038 0.0056
Schistosoma mansoni microtubule-associated protein tau 0.067 0.4046 0.6029
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0031 0.0041
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0147 0.0213
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0148 0.0816 0.1216
Entamoeba histolytica hypothetical protein 0.0036 0.0122 0.0113
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0019 0.0022 0.0018
Trypanosoma cruzi Protein kinase B 0.11 0.6707 1
Schistosoma mansoni ferritin light chain 0.002 0.0024 0.0029
Schistosoma mansoni hypothetical protein 0.0036 0.0122 0.0176
Brugia malayi Receptor family ligand binding region containing protein 0.0021 0.0035 0.0031
Loa Loa (eye worm) hypothetical protein 0.0021 0.0031 0.0027
Plasmodium vivax PH domain containing protein 0.0045 0.0179 0.0249
Schistosoma mansoni hypothetical protein 0.0171 0.0961 0.1427
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0144 0.0875
Brugia malayi p70 ribosomal S6 kinase beta 0.1587 0.9723 0.9723
Schistosoma mansoni serine/threonine-protein kinase 0.11 0.6707 1
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0045 0.0179 0.017
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0092 0.047 0.0687
Loa Loa (eye worm) hypothetical protein 0.0056 0.0247 0.0243
Echinococcus granulosus expressed protein 0.002 0.0024 0.0035
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0038 0.0148
Brugia malayi Pleckstrin Homology Domain 0.0045 0.0179 0.0175
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0228 0.0334
Loa Loa (eye worm) cytohesin 3 0.0045 0.0179 0.0175
Trichomonas vaginalis centaurin/arf, putative 0.0045 0.0179 0.017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0354 0.0344
Schistosoma mansoni pyruvate kinase 0.0037 0.0131 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0179 0.017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0324 0.0315
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0031 0.0027
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0112 0.0102
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0017 0.0009 0.0008
Leishmania major pyruvate kinase 0.0037 0.0131 0.0559
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0056 0.0247 0.1287
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0109 0.0107
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0056 0.0252 0.0362
Brugia malayi metabotropic glutamate receptor type 2 0.0041 0.0155 0.015
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0024 0.005 0.0041
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0045 0.0179 0.0253
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0144 0.0135
Echinococcus multilocularis protein kinase c iota type 0.0544 0.3268 0.4872
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0073 0.0354 0.1549
Echinococcus multilocularis pyruvate kinase 0.0019 0.0019 0.0029
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0038 0.0148
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Loa Loa (eye worm) hypothetical protein 0.0075 0.0364 0.036
Loa Loa (eye worm) hypothetical protein 0.0039 0.0144 0.014
Echinococcus granulosus lysine specific demethylase 6a 0.0025 0.0055 0.0081
Trypanosoma brucei protein kinase, putative 0.0056 0.0252 0.0242
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0045 0.0179 0.017
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0228 0.034
Loa Loa (eye worm) hypothetical protein 0.0056 0.0247 0.0243
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.1043 0.6358 0.9479
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0179 0.017
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0131 0.0121
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0022 0.0038 0.0033
Schistosoma mansoni glutaminase 0.03 0.1761 0.262
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0031 0.0027
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0189 0.0281
Loa Loa (eye worm) phosphatidylinositol 3 0.0031 0.0092 0.0088
Loa Loa (eye worm) hypothetical protein 0.0029 0.0083 0.0078
Entamoeba histolytica protein kinase, putative 0.0056 0.0252 0.0242
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0083 0.0117
Echinococcus multilocularis DCC interacting protein 13 beta 0.0045 0.0179 0.0267
Entamoeba histolytica PH domain containing protein 0.0045 0.0179 0.017
Echinococcus granulosus myotubularin protein 13 0.0045 0.0179 0.0267
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0045 0.0179 0.0175
Leishmania major 4-coumarate:coa ligase-like protein 0.0075 0.0364 0.1593
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0022 0.0038 0.0081
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0619 0.0615
Echinococcus multilocularis nervana 2 0.1043 0.6358 0.9479
Loa Loa (eye worm) hypothetical protein 0.0022 0.0038 0.0033
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0189 0.0275
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0075 0.0364 0.196
Schistosoma mansoni dynamin 0.0045 0.0179 0.0261
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0031 0.0092 0.0138
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0144 0.0135
Toxoplasma gondii t-complex protein beta subunit 0.0024 0.005 0.0047
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0038 0.0081
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0092 0.047 0.07
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Schistosoma mansoni coup transcription factor 0.0021 0.0031 0.0041
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0544 0.3268 0.4872
Trichomonas vaginalis kinesin light chain, putative 0.0045 0.0179 0.017
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0045 0.0179 0.017
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.049 0.0731
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0171 0.0961 0.1433
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0109 0.0156
Schistosoma mansoni hypothetical protein 0.0319 0.1876 0.2792
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0056 0.0252 0.0362
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.002 0.0024 0.5
Schistosoma mansoni hypothetical protein 0.0045 0.0179 0.0261
Toxoplasma gondii pyruvate kinase PyK1 0.0037 0.0131 0.013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0238 0.0229
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0031 0.0041
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0022 0.0033
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Schistosoma mansoni hypothetical protein 0.0536 0.3218 0.4795
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0045 0.0179 0.017
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0544 0.3268 0.3265
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0045 0.0179 0.017
Echinococcus granulosus protein kinase C gamma type 0.0544 0.3268 0.4872
Brugia malayi Dynamin 0.0045 0.0179 0.0175
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0022 0.0038 0.0081
Leishmania major pyruvate kinase 0.0037 0.0131 0.0559
Trichomonas vaginalis AGC family protein kinase 0.1632 1 1
Schistosoma mansoni pyruvate kinase 0.0037 0.0131 0.0188
Onchocerca volvulus 0.0075 0.0364 0.2287
Brugia malayi Pre-SET motif family protein 0.0033 0.0109 0.0104
Trypanosoma cruzi hypothetical protein 0.0045 0.0179 0.0253
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0045 0.0179 0.0267
Schistosoma mansoni serine/threonine protein kinase 0.0544 0.3268 0.4869
Loa Loa (eye worm) hypothetical protein 0.0019 0.0022 0.0017
Echinococcus multilocularis myotubularin protein 13 0.0045 0.0179 0.0267
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0228 0.034
Entamoeba histolytica hypothetical protein 0.0036 0.0122 0.0113
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0038 0.0028
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0038 0.0033
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Loa Loa (eye worm) hypothetical protein 0.0056 0.0247 0.0243
Echinococcus granulosus pyruvate kinase 0.0037 0.0131 0.0195
Schistosoma mansoni hypothetical protein 0.0148 0.0816 0.121
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0045 0.0179 0.017
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0045 0.0179 0.0249
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0241 0.0232
Echinococcus multilocularis cpg binding protein 0.0062 0.0288 0.0429
Mycobacterium ulcerans lipase LipD 0.0039 0.0144 0.0692
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0031 0.0047
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0031 0.0041
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Schistosoma mansoni hypothetical protein 0.0148 0.0816 0.121
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0022 0.0038 0.0132
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0045 0.0179 0.0272
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0045 0.0179 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0179 0.017
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0171 0.0961 0.1433
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0022 0.0038 0.0081
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0022 0.0038 0.0411
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0208 0.0199
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0054 0.0045
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0075 0.0364 0.196
Toxoplasma gondii histone lysine methyltransferase SET1 0.0113 0.06 0.0613
Onchocerca volvulus 0.0033 0.0109 0.0531
Echinococcus multilocularis Oxysterol binding protein 11 0.0045 0.0179 0.0267
Echinococcus multilocularis dynamin 1 0.0045 0.0179 0.0267
Brugia malayi jmjC domain containing protein 0.0025 0.0055 0.005
Mycobacterium leprae Probable lipase LipE 0.0039 0.0144 0.3531
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0144 0.0692
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0031 0.0027
Toxoplasma gondii pyruvate kinase PyKII 0.0019 0.0019 0.0015
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0045 0.0179 0.0267
Entamoeba histolytica hypothetical protein 0.0045 0.0179 0.017
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0544 0.3268 0.4869
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0045 0.0179 0.0267
Echinococcus granulosus pleckstrin y domain containing family A 0.0045 0.0179 0.0267
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0038 0.0042
Entamoeba histolytica PH domain containing protein kinase, putative 0.11 0.6707 0.6704
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0179 0.017
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0045 0.0179 0.0272
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0031 0.0047
Brugia malayi PH domain containing protein 0.0045 0.0179 0.0175
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0031 0.0027
Trichomonas vaginalis esterase, putative 0.0039 0.0144 0.0135
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0045 0.0179 0.017
Echinococcus granulosus dnaJ subfamily B 0.043 0.2561 0.3818
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0354 0.0344
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0031 0.0092 0.0088
Brugia malayi Syntrophin-1 0.0045 0.0179 0.0175
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0024 0.005 0.0075
Echinococcus granulosus beta 1 syntrophin 0.0045 0.0179 0.0267
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0182 0.1031 0.1537
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0815 0.4946 0.7374
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0073 0.0354 0.0345
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0209 0.0199
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.1043 0.6358 0.9479
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0045 0.0179 0.0267
Loa Loa (eye worm) hypothetical protein 0.0039 0.0144 0.014
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0148 0.0816 0.0812
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0144 0.0135
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0189 0.0184
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0024 0.005 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0354 0.0344
Loa Loa (eye worm) latrophilin receptor protein 2 0.0148 0.0816 0.0812
Schistosoma mansoni zinc finger protein 0.0045 0.0179 0.0261
Schistosoma mansoni hypothetical protein 0.0045 0.0179 0.0261
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0037 0.0131 0.0782
Echinococcus multilocularis GPCR, family 2 0.0148 0.0816 0.1216
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0974 0.0966
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0045 0.0179 0.017
Leishmania major hypothetical protein, conserved 0.0039 0.0144 0.0618
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0038 0.0081
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0036 0.0127 0.0189
Loa Loa (eye worm) beta-lactamase 0.0039 0.0144 0.014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0031 0.0047
Echinococcus granulosus cGMP dependent protein kinase 1 0.0017 0.0004 0.0006
Echinococcus granulosus cGMP dependent protein kinase 1 0.0017 0.0004 0.0006
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0045 0.0179 0.1014
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0045 0.0179 0.0272
Loa Loa (eye worm) hypothetical protein 0.0022 0.0038 0.0033
Giardia lamblia Kinase, AGC PKA 0.1055 0.643 1
Plasmodium falciparum PH domain-containing protein, putative 0.0045 0.0179 0.0272
Plasmodium vivax SET domain protein, putative 0.0033 0.0109 0.0139
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0056 0.0252 0.0242
Mycobacterium ulcerans pyruvate kinase 0.0037 0.0131 0.0615
Schistosoma mansoni serine/threonine kinase 0.0544 0.3268 0.4869
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0031 0.0041
Plasmodium falciparum pyruvate kinase 0.0037 0.0131 0.0197
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0045 0.0179 0.0261
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0131 0.0121
Echinococcus multilocularis Pleckstrin y 0.0045 0.0179 0.0267
Trichomonas vaginalis AGC family protein kinase 0.1632 1 1
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0189 0.0275
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0179 0.017
Entamoeba histolytica hypothetical protein 0.0045 0.0179 0.017
Toxoplasma gondii FATC domain-containing protein 0.0017 0.0009 0.0005
Echinococcus multilocularis Rho GTPase activating protein 24 0.0045 0.0179 0.0267
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0031 0.0047
Loa Loa (eye worm) hypothetical protein 0.0021 0.0031 0.0027
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0131 0.0181
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0031 0.0041
Schistosoma mansoni goodpasture antigen-binding protein 0.0045 0.0179 0.0261
Toxoplasma gondii hypothetical protein 0.0045 0.0179 0.018
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0209 0.0199
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0131 0.0681
Schistosoma mansoni jumonji domain containing protein 0.0133 0.0725 0.1076
Trichomonas vaginalis AGC family protein kinase 0.0544 0.3268 0.3261
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1453 0.1445
Schistosoma mansoni jumonji/arid domain-containing protein 0.0096 0.0495 0.0732
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0031 0.0027
Schistosoma mansoni hypothetical protein 0.0148 0.0816 0.121
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0126 0.0683 0.1012
Schistosoma mansoni cpg binding protein 0.0059 0.0267 0.0392
Entamoeba histolytica protein kinase 2, putative 0.1055 0.643 0.6427
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0031 0.0092 0.0083
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0056 0.0252 0.0362
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0031 0.0027
Schistosoma mansoni apoferritin-2 0.002 0.0024 0.0029
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0056 0.0247 1
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0144 0.0194
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Loa Loa (eye worm) glutaminase 0.03 0.1761 0.1757
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0251 0.1453 0.1449
Echinococcus granulosus nervana 2 0.1043 0.6358 0.9479
Onchocerca volvulus 0.0256 0.1486 1
Echinococcus multilocularis Glutaredoxin protein 5 0.1043 0.6358 0.9479
Loa Loa (eye worm) hypothetical protein 0.0075 0.0364 0.036
Brugia malayi hypothetical protein 0.0381 0.2263 0.2259
Echinococcus multilocularis protein kinase c epsilon type 0.0544 0.3268 0.4872
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Loa Loa (eye worm) hypothetical protein 0.0056 0.0247 0.0243
Brugia malayi CXXC zinc finger family protein 0.0059 0.0267 0.0263
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0324 0.0315
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.092 0.0911
Echinococcus multilocularis serine protein kinase ATM 0.0017 0.0009 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0109 0.0156
Echinococcus multilocularis pyruvate kinase 0.0029 0.0082 0.0123
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0038 0.0081
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0022 0.0038 0.0081
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0532 0.3195 0.3189
Plasmodium vivax ataxin-2 like protein, putative 0.0381 0.2263 0.3499
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0093 0.0139
Schistosoma mansoni zinc finger protein 0.0045 0.0179 0.0261
Echinococcus multilocularis Pleckstrin y 0.0045 0.0179 0.0267
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0031 0.0027
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0056 0.0252 0.0242
Brugia malayi Variant SH3 domain containing protein 0.0045 0.0179 0.0175
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Entamoeba histolytica p21-activated kinase 0.0056 0.0252 0.0242
Entamoeba histolytica hypothetical protein 0.0056 0.0252 0.0242
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0022 0.0038 0.0033
Leishmania major hypothetical protein, conserved 0.0045 0.0179 0.0774
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0225 0.1295 0.1291
Loa Loa (eye worm) hypothetical protein 0.0025 0.0055 0.005
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0075 0.0364 0.2417
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0092 0.047 0.0461
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0031 0.0027
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0109 0.0162
Loa Loa (eye worm) hypothetical protein 0.0031 0.0097 0.0093
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0045 0.0179 0.0175
Leishmania major 4-coumarate:coa ligase-like protein 0.0075 0.0364 0.1593
Brugia malayi ecdysteroid receptor 0.0021 0.0031 0.0027
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0031 0.0027
Brugia malayi hypothetical protein 0.0036 0.0122 0.0118
Trypanosoma cruzi hypothetical protein 0.0045 0.0179 0.0253
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.049 0.0725
Echinococcus multilocularis oxysterol binding protein 3 0.0045 0.0179 0.0267
Echinococcus multilocularis pdz domain containing protein 0.0045 0.0179 0.0267
Echinococcus granulosus serine threonine protein kinase nrc 0.1055 0.643 0.9587
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0092 0.0083
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0083 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0354 0.0344
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0208 0.0199
Schistosoma mansoni ferritin 0.002 0.0024 0.0029
Schistosoma mansoni serine/threonine-protein kinase 0.11 0.6707 1
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0038 0.0138 0.0129
Onchocerca volvulus 0.0045 0.0179 0.1014
Trypanosoma cruzi PAB1-binding protein , putative 0.0381 0.2263 0.3364
Schistosoma mansoni oxysterol-binding protein 1 0.0045 0.0179 0.0261
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1453 0.1445
Loa Loa (eye worm) T-complex protein 1 0.0024 0.005 0.0046
Echinococcus granulosus DCC interacting protein 13 beta 0.0045 0.0179 0.0267
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.005 0.0069
Schistosoma mansoni dynamin 0.0045 0.0179 0.0261
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0022 0.0038 0.0056
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.047 0.0461
Entamoeba histolytica hypothetical protein 0.0036 0.0122 0.0113
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0028 0.0075 0.0112
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0056 0.0252 0.0242
Echinococcus granulosus Pleckstrin y 0.0045 0.0179 0.0267
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0009 0.0005
Echinococcus granulosus pyruvate kinase 0.0037 0.0131 0.0195
Entamoeba histolytica hypothetical protein 0.0036 0.0122 0.0113
Trichomonas vaginalis centaurin gamma, putative 0.0045 0.0179 0.017
Loa Loa (eye worm) syntrophin-1 0.0045 0.0179 0.0175
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1453 0.1445
Trypanosoma brucei PH domain containing protein, putative 0.0045 0.0179 0.017
Echinococcus granulosus calcium dependent secretion activator 1 0.0045 0.0179 0.0267
Echinococcus multilocularis cytohesin 1 0.0045 0.0179 0.0267
Schistosoma mansoni rho gtpase activating protein 0.0045 0.0179 0.0261
Brugia malayi PH domain containing protein 0.0045 0.0179 0.0175
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0095 0.0491 0.0727
Echinococcus granulosus serine/threonine protein kinase 0.11 0.6707 1
Onchocerca volvulus 0.0045 0.0179 0.1014
Loa Loa (eye worm) hypothetical protein 0.0039 0.0144 0.014
Loa Loa (eye worm) hypothetical protein 0.0021 0.0031 0.0027
Brugia malayi Pyruvate kinase, muscle isozyme 0.0037 0.0131 0.0126
Trichomonas vaginalis centaurin/arf, putative 0.0045 0.0179 0.017
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0038 0.0028
Entamoeba histolytica hypothetical protein 0.0045 0.0179 0.017
Echinococcus granulosus protein kinase c iota type 0.0544 0.3268 0.4872
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0056 0.0252 0.0362
Loa Loa (eye worm) hypothetical protein 0.0039 0.0144 0.014
Schistosoma mansoni apoferritin-2 0.002 0.0024 0.0029
Leishmania major phosphatidylinositol 3-kinase, putative 0.0031 0.0092 0.039
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0122 0.0182
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0021 0.0035 0.0031
Echinococcus multilocularis jumonji domain containing 1A 0.0025 0.0055 0.0081
Plasmodium vivax hypothetical protein, conserved 0.0045 0.0179 0.0249
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0354 0.0344
Entamoeba histolytica pyruvate kinase, putative 0.0026 0.0061 0.0052
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0045 0.0179 0.0249
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0056 0.0252 0.0362
Echinococcus granulosus GPCR family 2 0.0148 0.0816 0.1216
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0045 0.0179 0.017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0092 0.0083
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0031 0.0041
Echinococcus granulosus pyruvate kinase 0.0019 0.0019 0.0029
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0045 0.0179 0.017
Entamoeba histolytica PH domain containing protein kinase, putative 0.0056 0.0252 0.0242
Schistosoma mansoni oxysterol-binding protein 1 0.0045 0.0179 0.0261
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0022 0.0012
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0103 0.054 0.0805
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0045 0.0179 0.0261
Echinococcus multilocularis nervana 2 0.1043 0.6358 0.9479
Mycobacterium ulcerans beta-lactamase 0.0039 0.0144 0.0692
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0056 0.0252 0.0242
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0144 0.0135
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0038 0.0042
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0056 0.0252 0.0362
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0031 0.0092 0.0083
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0045 0.0179 0.0175
Loa Loa (eye worm) rho-GTPase-activating 0.0045 0.0179 0.0175
Echinococcus multilocularis Pleckstrin y 0.0045 0.0179 0.0267
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0056 0.0252 0.1095
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0045 0.0179 0.0267
Schistosoma mansoni growth factor receptor-bound protein 0.0045 0.0179 0.0261
Leishmania major hypothetical protein, conserved 0.0381 0.2263 1
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1453 0.1445
Brugia malayi probable spectrin beta chain 0.0045 0.0179 0.0175
Echinococcus granulosus pyruvate kinase 0.0019 0.0019 0.0029
Toxoplasma gondii AGC kinase 0.1587 0.9723 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0144 0.0135
Schistosoma mansoni ferritin light chain 0.002 0.0024 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.092 0.0911
Schistosoma mansoni metabotropic glutamate receptor 0.007 0.0336 0.0495
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0283 0.0274
Plasmodium falciparum JmjC domain-containing protein, putative 0.0025 0.0055 0.0078
Giardia lamblia GTOR 0.0092 0.047 0.0703
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0038 0.0132
Loa Loa (eye worm) hypothetical protein 0.0046 0.0189 0.0184
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0075 0.0364 1
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0045 0.0179 0.017
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.1055 0.643 1
Loa Loa (eye worm) hypothetical protein 0.0075 0.0364 0.036
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0031 0.0092 0.0124
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0031 0.0092 0.039
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0022 0.0038 0.0132
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0017 0.0009 0.0014
Toxoplasma gondii protein kinase domain-containing protein 0.0056 0.0252 0.0254
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0031 0.0041
Trypanosoma cruzi PH domain containing protein, putative 0.0045 0.0179 0.0253
Echinococcus granulosus pdz domain containing protein 0.0045 0.0179 0.0267
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0092 0.047 0.2061
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0182 0.1031 0.1537
Schistosoma mansoni jumonji/arid domain-containing protein 0.0096 0.0495 0.0732
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0144 0.0875
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0179 0.017
Schistosoma mansoni ferritin 0.002 0.0024 0.0029
Leishmania major T-complex protein 1, beta subunit, putative 0.0024 0.005 0.0204
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0038 0.0042
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0031 0.0047
Echinococcus granulosus protein kinase c epsilon type 0.0544 0.3268 0.4872
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.0387 0.0378
Schistosoma mansoni ferritin 0.002 0.0024 0.0029
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0024 0.005 0.0075
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0022 0.0038 0.0081
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Echinococcus granulosus JmjC domain containing protein 4 0.0025 0.0055 0.0081
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0045 0.0179 0.0261
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0209 0.0199
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0031 0.0047
Echinococcus granulosus cGMP dependent protein kinase 0.0017 0.0004 0.0006
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0045 0.0179 0.017
Entamoeba histolytica hypothetical protein, conserved 0.0045 0.0179 0.017
Echinococcus granulosus oxysterol binding protein 3 0.0045 0.0179 0.0267
Schistosoma mansoni jumonji domain containing protein 0.0025 0.0055 0.0075
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0031 0.0027
Brugia malayi Cytohesin 3 0.0045 0.0179 0.0175
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0031 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0544 0.3268 0.4869
Loa Loa (eye worm) hypothetical protein 0.0021 0.0031 0.0027
Brugia malayi Oxysterol binding protein 0.0045 0.0179 0.0175
Schistosoma mansoni pyruvate kinase 0.0019 0.0019 0.0022
Onchocerca volvulus 0.0022 0.0038 0.0043
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0144 0.0215
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0022 0.0038 0.0411
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0031 0.0047
Brugia malayi PH domain containing protein 0.0045 0.0179 0.0175
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0013
Trypanosoma cruzi target of rapamycin kinase 3 0.0073 0.0354 0.0515
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0017 0.0004 0.0006
Toxoplasma gondii propionate-CoA ligase 0.0022 0.0038 0.0034
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0038 0.0033
Loa Loa (eye worm) hypothetical protein 0.0053 0.0228 0.0224
Echinococcus multilocularis oxysterol binding protein 9 0.0045 0.0179 0.0267
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0031 0.0041
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0189 0.0275
Echinococcus granulosus peregrin 0.0029 0.0083 0.0123
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0025 0.0055 0.0052
Brugia malayi hypothetical protein 0.0246 0.1426 0.1422
Schistosoma mansoni metabotropic glutamate receptor 0.0041 0.0155 0.0224
Schistosoma mansoni hypothetical protein 0.043 0.2561 0.3814
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Brugia malayi PH domain containing protein 0.0045 0.0179 0.0175
Entamoeba histolytica PH domain containing protein kinase, putative 0.0056 0.0252 0.0242
Echinococcus granulosus metabotropic glutamate receptor 5 0.0103 0.054 0.0805
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0031 0.0092 0.0138
Loa Loa (eye worm) pyruvate kinase-PB 0.0026 0.0061 0.0057
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0031 0.0047
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0974 0.0966
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0179 0.017
Loa Loa (eye worm) hypothetical protein 0.0056 0.0247 0.0243
Trichomonas vaginalis AGC family protein kinase 0.1632 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0144 0.0201
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0467 0.2789 0.2786
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.092 0.0911
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.092 0.0911
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0045 0.0179 0.017
Schistosoma mansoni centaurin alpha 0.0045 0.0179 0.0261
Schistosoma mansoni hypothetical protein 0.0029 0.0083 0.0117
Entamoeba histolytica hypothetical protein 0.0056 0.0252 0.0242
Echinococcus multilocularis ferritin 0.002 0.0024 0.0035
Loa Loa (eye worm) hypothetical protein 0.0065 0.0306 0.0302
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0022 0.0038 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0271 0.0261
Brugia malayi Protein kinase domain containing protein 0.0544 0.3268 0.3265
Toxoplasma gondii ABC1 family protein 0.0039 0.0144 0.0144
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0031 0.0047
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.005 0.0069
Echinococcus granulosus pyruvate kinase 0.0019 0.0019 0.0029
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0544 0.3268 0.3265
Trichomonas vaginalis ferritin, putative 0.002 0.0024 0.0014
Echinococcus granulosus ferritin 0.002 0.0024 0.0035
Echinococcus granulosus neuropeptide receptor A26 0.0451 0.2694 0.4017
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0228 0.034
Trichomonas vaginalis AGC family protein kinase 0.0589 0.3545 0.3538
Echinococcus granulosus phd:f box containing protein 0.0025 0.0055 0.0081
Leishmania major 4-coumarate:coa ligase-like protein 0.0075 0.0364 0.1593
Mycobacterium ulcerans acyl-CoA synthetase 0.0075 0.0364 0.196
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0038 0.0081
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0022 0.0038 0.0034
Brugia malayi AMP-binding enzyme family protein 0.0075 0.0364 0.036
Mycobacterium leprae Probable pyruvate kinase PykA 0.0037 0.0131 0.314
Plasmodium vivax pyruvate kinase, putative 0.0037 0.0131 0.0174
Loa Loa (eye worm) MBCTL1 0.0053 0.0228 0.0224
Schistosoma mansoni serine/threonine protein kinase 0.0544 0.3268 0.4869
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0056 0.0252 0.0362
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0109 0.0162
Mycobacterium tuberculosis Conserved protein 0.0039 0.0144 0.0875
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Mycobacterium tuberculosis Conserved protein 0.0039 0.0144 0.0875
Plasmodium falciparum calcium-dependent protein kinase 7 0.0056 0.0252 0.0385
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0045 0.0179 0.017
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0267 0.0263
Echinococcus multilocularis pyruvate kinase 0.0019 0.0019 0.0029
Echinococcus multilocularis pleckstrin y domain containing family A 0.0045 0.0179 0.0267
Trichomonas vaginalis hypothetical protein 0.0045 0.0179 0.017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0324 0.0315
Echinococcus granulosus Protein kinase C brain isozyme 0.0544 0.3268 0.4872
Loa Loa (eye worm) hypothetical protein 0.0021 0.0031 0.0027
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0022 0.0038 0.0028
Loa Loa (eye worm) hypothetical protein 0.0037 0.0131 0.0126
Echinococcus granulosus GRB2 associated binding protein 3 0.0045 0.0179 0.0267
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0255 0.1482 0.221
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0025 0.0055 0.0067
Loa Loa (eye worm) oxidoreductase 0.0022 0.0038 0.0033
Brugia malayi hypothetical protein 0.0151 0.0834 0.083
Onchocerca volvulus 0.0045 0.0179 0.1014
Echinococcus granulosus microtubule associated protein 2 0.067 0.4046 0.6032
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.049 0.0486
Trichomonas vaginalis AGC family protein kinase 0.1632 1 1
Entamoeba histolytica PH domain containing protein 0.0045 0.0179 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0179 0.017
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0056 0.0252 0.0254
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0092 0.047 0.07
Onchocerca volvulus 0.0046 0.0189 0.1079
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0038 0.0132
Onchocerca volvulus 0.0045 0.0179 0.1014
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.049 0.0725
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.049 0.0486
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0031 0.0027
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0083 0.0123
Loa Loa (eye worm) jmjC domain-containing protein 0.0025 0.0055 0.005
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.005 0.0046
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0045 0.0179 0.0267
Echinococcus granulosus Glutaredoxin protein 5 0.1043 0.6358 0.9479
Echinococcus granulosus jumonji domain containing 1A 0.0025 0.0055 0.0081
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Schistosoma mansoni hypothetical protein 0.0148 0.0816 0.121
Schistosoma mansoni syntrophin 0.0045 0.0179 0.0261
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0017 0.0004 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0324 0.0315
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.092 0.0911
Brugia malayi beta-lactamase 0.0039 0.0144 0.014
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0228 0.0224
Mycobacterium ulcerans hypothetical protein 0.0039 0.0144 0.0692
Schistosoma mansoni serine/threonine protein kinase 0.0544 0.3268 0.4869
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0179 0.017
Loa Loa (eye worm) phosphatidylinositol 3 0.0092 0.047 0.0466
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0179 0.017
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0038 0.0081
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0022 0.0033
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0038 0.0148
Brugia malayi PH domain containing protein 0.0045 0.0179 0.0175
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.049 0.0731
Trypanosoma cruzi rac serine-threonine kinase, putative 0.1055 0.643 0.9587
Trypanosoma brucei PAB1-binding protein , putative 0.0381 0.2263 0.2255
Trichomonas vaginalis centaurin alpha, putative 0.0045 0.0179 0.017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0238 0.0229
Schistosoma mansoni hypothetical protein 0.0281 0.1643 0.2445
Schistosoma mansoni phd/f-box containing protein 0.0025 0.0055 0.0075
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0024 0.005 0.0048
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0075 0.0364 1
Brugia malayi Bromodomain containing protein 0.0029 0.0083 0.0078
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0083 0.0081
Brugia malayi AMP-binding enzyme family protein 0.0075 0.0364 0.036
Brugia malayi protein kinase C II. 0.0544 0.3268 0.3265
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0045 0.0179 0.0267
Brugia malayi PH domain containing protein 0.0045 0.0179 0.0175
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0022 0.0038 0.0132
Plasmodium falciparum ataxin-2 like protein, putative 0.0381 0.2263 0.3515
Schistosoma mansoni cpg binding protein 0.0062 0.0288 0.0423
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.005 0.0046
Trichomonas vaginalis protein transport protein sec7, putative 0.0045 0.0179 0.017
Entamoeba histolytica PH domain containing protein kinase, putative 0.0056 0.0252 0.0242
Trypanosoma brucei pyruvate kinase 1 0.0037 0.0131 0.0121
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0131 0.0126
Echinococcus multilocularis GRB2 associated binding protein 3 0.0045 0.0179 0.0267
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0153 0.0847 0.1263
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0036 0.0127 0.0122
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0045 0.0179 0.0175
Brugia malayi Oxysterol-binding protein 0.0045 0.0179 0.0175
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1453 0.1445
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0251 0.1453 0.1449
Echinococcus multilocularis beta 1 syntrophin 0.0045 0.0179 0.0267
Echinococcus multilocularis expressed conserved protein 0.0017 0.0004 0.0006
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0022 0.0018
Brugia malayi steroid hormone receptor 0.0021 0.0031 0.0027
Loa Loa (eye worm) hypothetical protein 0.0045 0.0179 0.0175
Entamoeba histolytica protein kinase, putative 0.0056 0.0252 0.0242
Giardia lamblia PHD finger protein 15 0.0029 0.0083 0.0099
Giardia lamblia TCP-1 chaperonin subunit beta 0.0024 0.005 0.0048
Entamoeba histolytica acyl-CoA synthetase, putative 0.0075 0.0364 0.0355
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0189 0.0281
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0228 0.034
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0038 0.0411
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0144 0.3531
Mycobacterium tuberculosis Bacterioferritin BfrB 0.002 0.0024 0.0034
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0252 0.0242
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0038 0.0033
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0022 0.0038 0.0132
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0031 0.0047
Entamoeba histolytica protein kinase, putative 0.0056 0.0252 0.0242
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0022 0.0038 0.0028
Entamoeba histolytica acyl-CoA synthetase, putative 0.0075 0.0364 0.0355
Echinococcus multilocularis neuropeptide receptor A26 0.0451 0.2694 0.4017
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0144 0.0875
Leishmania major folate/biopterin transporter, putative 0.0056 0.0252 0.1095
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0131 0.0126

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.1032 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.1158 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.2589 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 1.5849 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 4.1475 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 11.6891 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 15.8489 uM PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 23.0999 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 23.1093 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.