Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0008 | 0.0316 | 0.0316 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.005 | 0.4044 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.4044 | 0.5 |
Trypanosoma brucei | protein kinase, putative | 0.005 | 0.4044 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.005 | 0.4044 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.005 | 0.4044 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.005 | 0.4044 | 0.5 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0117 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.4044 | 0.5 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.005 | 0.4044 | 0.5 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.4044 | 0.5 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0316 | 0.0316 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0316 | 0.0316 |
Brugia malayi | MAP kinase sur-1 | 0.005 | 0.4044 | 0.4044 |
Echinococcus granulosus | mitogen activated protein kinase | 0.005 | 0.4044 | 1 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.005 | 0.4044 | 0.5 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.005 | 0.4044 | 0.4044 |
Loa Loa (eye worm) | Smad1 | 0.0008 | 0.0316 | 0.0316 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0316 | 0.0316 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.4044 | 0.5 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.005 | 0.4044 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0008 | 0.0316 | 0.0316 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0316 | 0.0316 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.4044 | 0.5 |
Giardia lamblia | Kinase, CMGC MAPK | 0.005 | 0.4044 | 0.5 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.005 | 0.4044 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0117 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.4044 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.005 | 0.4044 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.005 | 0.4044 | 1 |
Brugia malayi | Smad1 | 0.0008 | 0.0316 | 0.0316 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.