Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.008 | 0.0952 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.008 | 0.0952 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0149 | 0.4083 | 0.3477 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.008 | 0.0952 | 0.0952 |
Brugia malayi | G-protein coupled receptor | 0.0149 | 0.4083 | 0.346 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Brugia malayi | Serotonin receptor | 0.0149 | 0.4083 | 0.346 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0149 | 0.4083 | 1 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.008 | 0.0952 | 0.5 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.008 | 0.0952 | 0.5 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.008 | 0.0952 | 0.0026 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | 6 phosphofructo 2 kinase:fructose 2 | 0.0139 | 0.3631 | 0.8556 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0149 | 0.4083 | 1 |
Giardia lamblia | Hypothetical protein | 0.0082 | 0.1035 | 0.5 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Schistosoma mansoni | myosin xvIII | 0.0149 | 0.4083 | 1 |
Brugia malayi | G protein-coupled receptor | 0.0149 | 0.4083 | 0.346 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0278 | 1 | 1 |
Brugia malayi | putative neuropeptide receptor | 0.0149 | 0.4083 | 0.346 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0149 | 0.4083 | 0.3477 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.008 | 0.0952 | 0.5 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.008 | 0.0952 | 0.5 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0149 | 0.4083 | 1 |
Trypanosoma brucei | 6-phosphofructo-2-kinase 2 | 0.0136 | 0.3524 | 0.3524 |
Schistosoma mansoni | hypothetical protein | 0.0149 | 0.4083 | 1 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0139 | 0.3631 | 0.3631 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.3631 | 0.2979 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0149 | 0.4083 | 1 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.0082 | 0.1035 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0149 | 0.4083 | 1 |
Giardia lamblia | Hypothetical protein | 0.0082 | 0.1035 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | adenoreceptor | 0.0149 | 0.4083 | 1 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0149 | 0.4083 | 0.346 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.008 | 0.0952 | 0.5 |
Mycobacterium ulcerans | fructose-2,6-bisphosphatase GpmB | 0.0082 | 0.1035 | 0.0092 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Brugia malayi | G-protein coupled receptor | 0.0149 | 0.4083 | 0.346 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.008 | 0.0952 | 0.0952 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0278 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.3524 | 0.2861 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Brugia malayi | Melatonin receptor type 1A | 0.0149 | 0.4083 | 0.346 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0149 | 0.4083 | 1 |
Brugia malayi | sulfakinin receptor protein | 0.0149 | 0.4083 | 0.346 |
Schistosoma mansoni | opsin-like receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0149 | 0.4083 | 0.3477 |
Leishmania major | cytochrome p450-like protein | 0.008 | 0.0952 | 0.0952 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.008 | 0.0952 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.008 | 0.0952 | 0.5 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0149 | 0.4083 | 0.346 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | fmrfamide receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.008 | 0.0952 | 0.5 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.008 | 0.0952 | 0.0952 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Mycobacterium leprae | putative cytochrome p450 | 0.008 | 0.0952 | 0.5 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.008 | 0.0952 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.008 | 0.0952 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.6345 | 0.5971 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0278 | 1 | 1 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0149 | 0.4083 | 1 |
Trypanosoma brucei | cytochrome P450, putative | 0.0278 | 1 | 1 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0149 | 0.4083 | 0.3477 |
Echinococcus granulosus | g protein coupled receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | histamine h1 receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0149 | 0.4083 | 1 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0149 | 0.4083 | 0.346 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Brugia malayi | Dopamine receptor protein 2 | 0.0149 | 0.4083 | 0.346 |
Echinococcus multilocularis | neuropeptide receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Schistosoma mansoni | biogenic amine receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | serotonin receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0149 | 0.4083 | 0.3477 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0139 | 0.3631 | 0.3631 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0149 | 0.4083 | 0.3477 |
Schistosoma mansoni | amine GPCR | 0.0149 | 0.4083 | 1 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.008 | 0.0952 | 0.5 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0149 | 0.4083 | 1 |
Brugia malayi | Dopamine receptor protein 1 | 0.0149 | 0.4083 | 0.346 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0149 | 0.4083 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0278 | 1 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0149 | 0.4083 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0278 | 1 | 1 |
Brugia malayi | ORL1-like opioid receptor | 0.0149 | 0.4083 | 0.346 |
Brugia malayi | follicle stimulating hormone receptor | 0.0149 | 0.4083 | 0.346 |
Schistosoma mansoni | neuropeptide receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | amine GPCR | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0149 | 0.4083 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.008 | 0.0952 | 0.5 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.008 | 0.0952 | 0.0952 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | serotonin receptor | 0.0149 | 0.4083 | 1 |
Brugia malayi | GnHR receptor homolog | 0.0149 | 0.4083 | 0.346 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0149 | 0.4083 | 0.346 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.008 | 0.0952 | 0.5 |
Echinococcus multilocularis | sex peptide receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0149 | 0.4083 | 0.346 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0149 | 0.4083 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.008 | 0.0952 | 0.5 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | somatostatin receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.008 | 0.0952 | 0.5 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Brugia malayi | RE15519p | 0.0149 | 0.4083 | 0.346 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0136 | 0.3524 | 0.3524 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | orexin receptor type 2 | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Schistosoma mansoni | amine GPCR | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0149 | 0.4083 | 0.346 |
Leishmania major | cytochrome p450-like protein | 0.0278 | 1 | 1 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | g protein coupled receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Leishmania major | cytochrome p450-like protein | 0.008 | 0.0952 | 0.0952 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.008 | 0.0952 | 0.5 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0149 | 0.4083 | 1 |
Brugia malayi | Dopamine receptor | 0.0149 | 0.4083 | 0.346 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0149 | 0.4083 | 1 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.008 | 0.0952 | 0.0952 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.008 | 0.0952 | 0.5 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0149 | 0.4083 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.008 | 0.0952 | 0.5 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Brugia malayi | larval opioid receptor | 0.0149 | 0.4083 | 0.346 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Schistosoma mansoni | biogenic amine receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0149 | 0.4083 | 1 |
Brugia malayi | AKH receptor | 0.0149 | 0.4083 | 0.346 |
Echinococcus granulosus | g-protein coupled receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | neuropeptide s receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0149 | 0.4083 | 1 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Echinococcus granulosus | g protein coupled receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | allatostatin A receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Schistosoma mansoni | opsin-like receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | allatostatin A receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0139 | 0.3631 | 0.8556 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.0136 | 0.3524 | 0.3524 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Mycobacterium ulcerans | hypothetical protein | 0.0082 | 0.1035 | 0.0092 |
Echinococcus granulosus | somatostatin receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0149 | 0.4083 | 1 |
Brugia malayi | Serotonin receptor | 0.0149 | 0.4083 | 0.346 |
Echinococcus granulosus | neuropeptide receptor | 0.0149 | 0.4083 | 1 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.008 | 0.0952 | 0.5 |
Echinococcus granulosus | sex peptide receptor | 0.0149 | 0.4083 | 1 |
Brugia malayi | neuropeptide F receptor | 0.0149 | 0.4083 | 0.346 |
Brugia malayi | neuropeptide F receptor | 0.0149 | 0.4083 | 0.346 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0149 | 0.4083 | 0.346 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0139 | 0.3631 | 0.3631 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | amine GPCR | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0149 | 0.4083 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.0136 | 0.3524 | 0.3524 |
Echinococcus multilocularis | serotonin receptor | 0.0149 | 0.4083 | 1 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0149 | 0.4083 | 0.346 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | amine GPCR | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0149 | 0.4083 | 0.3477 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0149 | 0.4083 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.008 | 0.0952 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0139 | 0.3631 | 0.3631 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | cytochrome P450 | 0.008 | 0.0952 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | 6 phosphofructo 2 kinase:fructose 2 | 0.0139 | 0.3631 | 0.8556 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Echinococcus multilocularis | fmrfamide receptor | 0.0149 | 0.4083 | 1 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0278 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0278 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0149 | 0.4083 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Concentration (functional) | = 79 ng ml-1 | Plasma concentration was determined after 30 min of oral administration of the compound in mice | ChEMBL. | 3656350 |
Concentration (functional) | = 79 ng ml-1 | Plasma concentration was determined after 30 min of oral administration of the compound in mice | ChEMBL. | 3656350 |
Concentration (functional) | = 91 ng ml-1 | Plasma concentration was determined after 120 min of oral administration of the compound in mice | ChEMBL. | 3656350 |
Concentration (functional) | = 91 ng ml-1 | Plasma concentration was determined after 120 min of oral administration of the compound in mice | ChEMBL. | 3656350 |
Concentration (functional) | = 97 ng ml-1 | Plasma concentration was determined after 60 min of oral administration of the compound in mice | ChEMBL. | 3656350 |
Concentration (functional) | = 97 ng ml-1 | Plasma concentration was determined after 60 min of oral administration of the compound in mice | ChEMBL. | 3656350 |
ED50 (functional) | = 4.5 mg kg-1 | Antagonistic activity against MES (Maximal Elecroshock)-induced seizures after oral administration to mice | ChEMBL. | 3656350 |
ED50 (functional) | = 4.5 mg kg-1 | Antagonistic activity against MES (Maximal Elecroshock)-induced seizures after oral administration to mice | ChEMBL. | 3656350 |
ED50 (functional) | = 56 mg kg-1 | Ataxia or neurological deficit was measured as horizontal screen test(HS) in mice | ChEMBL. | 3656350 |
ED50 (functional) | = 56 mg kg-1 | Ataxia or neurological deficit was measured as horizontal screen test(HS) in mice | ChEMBL. | 3656350 |
TPE (functional) | = 1 hr | Time taken for peak anticonvulsant effect(TPE) was measured by oral administration to mice | ChEMBL. | 3656350 |
TPE (functional) | = 1 hr | Time taken for peak anticonvulsant effect(TPE) was measured by oral administration to mice | ChEMBL. | 3656350 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.