Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus granulosus | orexin receptor type 2 | 0.0149 | 0.4083 | 1 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.008 | 0.0952 | 0.0952 |
Echinococcus multilocularis | allatostatin A receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0149 | 0.4083 | 0.3477 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0149 | 0.4083 | 1 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0139 | 0.3631 | 0.3631 |
Loa Loa (eye worm) | cytochrome P450 | 0.008 | 0.0952 | 0.0026 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0149 | 0.4083 | 1 |
Brugia malayi | G-protein coupled receptor | 0.0149 | 0.4083 | 0.346 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0149 | 0.4083 | 0.346 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0149 | 0.4083 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.008 | 0.0952 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.008 | 0.0952 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.008 | 0.0952 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.0149 | 0.4083 | 1 |
Trypanosoma brucei | 6-phosphofructo-2-kinase 2 | 0.0136 | 0.3524 | 0.3524 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Mycobacterium ulcerans | fructose-2,6-bisphosphatase GpmB | 0.0082 | 0.1035 | 0.0092 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.008 | 0.0952 | 0.5 |
Schistosoma mansoni | opsin-like receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Echinococcus granulosus | sex peptide receptor | 0.0149 | 0.4083 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.008 | 0.0952 | 0.5 |
Brugia malayi | neuropeptide F receptor | 0.0149 | 0.4083 | 0.346 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Schistosoma mansoni | amine GPCR | 0.0149 | 0.4083 | 1 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Trypanosoma brucei | cytochrome P450, putative | 0.0278 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.3631 | 0.2979 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0149 | 0.4083 | 0.346 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0149 | 0.4083 | 1 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.008 | 0.0952 | 0.0026 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0149 | 0.4083 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.008 | 0.0952 | 0.5 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | myosin xvIII | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | allatostatin A receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | g-protein coupled receptor | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Echinococcus multilocularis | neuropeptide s receptor | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.3524 | 0.2861 |
Schistosoma mansoni | hypothetical protein | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.008 | 0.0952 | 0.5 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0278 | 1 | 1 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0149 | 0.4083 | 1 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0149 | 0.4083 | 0.346 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.0082 | 0.1035 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.008 | 0.0952 | 0.5 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.008 | 0.0952 | 0.0952 |
Brugia malayi | G protein-coupled receptor | 0.0149 | 0.4083 | 0.346 |
Echinococcus granulosus | neuropeptide s receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | adenoreceptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | amine GPCR | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0149 | 0.4083 | 0.3477 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0149 | 0.4083 | 0.3477 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.6345 | 0.5971 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0139 | 0.3631 | 0.3631 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0139 | 0.3631 | 0.3631 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0149 | 0.4083 | 0.3477 |
Brugia malayi | GnHR receptor homolog | 0.0149 | 0.4083 | 0.346 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0149 | 0.4083 | 1 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.008 | 0.0952 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Leishmania major | cytochrome p450-like protein | 0.008 | 0.0952 | 0.0952 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.008 | 0.0952 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0149 | 0.4083 | 1 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.008 | 0.0952 | 0.0952 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0149 | 0.4083 | 0.346 |
Echinococcus granulosus | g protein coupled receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | 6 phosphofructo 2 kinase:fructose 2 | 0.0139 | 0.3631 | 0.8556 |
Schistosoma mansoni | biogenic amine receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0149 | 0.4083 | 1 |
Brugia malayi | Dopamine receptor protein 2 | 0.0149 | 0.4083 | 0.346 |
Brugia malayi | neuropeptide F receptor | 0.0149 | 0.4083 | 0.346 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus granulosus | hypothetical protein | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Mycobacterium leprae | putative cytochrome p450 | 0.008 | 0.0952 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0149 | 0.4083 | 1 |
Brugia malayi | larval opioid receptor | 0.0149 | 0.4083 | 0.346 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0149 | 0.4083 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0278 | 1 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0149 | 0.4083 | 1 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.008 | 0.0952 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.008 | 0.0952 | 0.5 |
Brugia malayi | putative neuropeptide receptor | 0.0149 | 0.4083 | 0.346 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.008 | 0.0952 | 0.5 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | g protein coupled receptor | 0.0149 | 0.4083 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0278 | 1 | 1 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0149 | 0.4083 | 0.346 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Brugia malayi | ORL1-like opioid receptor | 0.0149 | 0.4083 | 0.346 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.008 | 0.0952 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0149 | 0.4083 | 0.3477 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Echinococcus multilocularis | fmrfamide receptor | 0.0149 | 0.4083 | 1 |
Giardia lamblia | Hypothetical protein | 0.0082 | 0.1035 | 0.5 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | fmrfamide receptor | 0.0149 | 0.4083 | 1 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.008 | 0.0952 | 0.5 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.008 | 0.0952 | 0.5 |
Echinococcus multilocularis | somatostatin receptor | 0.0149 | 0.4083 | 1 |
Brugia malayi | RE15519p | 0.0149 | 0.4083 | 0.346 |
Schistosoma mansoni | neuropeptide receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0149 | 0.4083 | 1 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.008 | 0.0952 | 0.0952 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | amine GPCR | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0149 | 0.4083 | 1 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.008 | 0.0952 | 0.0952 |
Brugia malayi | Melatonin receptor type 1A | 0.0149 | 0.4083 | 0.346 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0278 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0149 | 0.4083 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.0136 | 0.3524 | 0.3524 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Echinococcus granulosus | neuropeptides capa receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | serotonin receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.008 | 0.0952 | 0.5 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0149 | 0.4083 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0139 | 0.3631 | 0.3631 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | neuropeptide receptor | 0.0149 | 0.4083 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.0136 | 0.3524 | 0.3524 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0149 | 0.4083 | 0.3477 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.008 | 0.0952 | 0.5 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Schistosoma mansoni | amine GPCR | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0149 | 0.4083 | 1 |
Brugia malayi | Serotonin receptor | 0.0149 | 0.4083 | 0.346 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0149 | 0.4083 | 0.346 |
Brugia malayi | Serotonin receptor | 0.0149 | 0.4083 | 0.346 |
Schistosoma mansoni | opsin-like receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0149 | 0.4083 | 1 |
Brugia malayi | Dopamine receptor | 0.0149 | 0.4083 | 0.346 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0149 | 0.4083 | 1 |
Brugia malayi | G-protein coupled receptor | 0.0149 | 0.4083 | 0.346 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | histamine h1 receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0278 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.008 | 0.0952 | 0.5 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.008 | 0.0952 | 0.5 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.008 | 0.0952 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Schistosoma mansoni | neuropeptide receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0149 | 0.4083 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0149 | 0.4083 | 0.346 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0149 | 0.4083 | 0.3477 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0149 | 0.4083 | 1 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Mycobacterium ulcerans | hypothetical protein | 0.0082 | 0.1035 | 0.0092 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0149 | 0.4083 | 1 |
Giardia lamblia | Hypothetical protein | 0.0082 | 0.1035 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0149 | 0.4083 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | amine GPCR | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | serotonin receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0149 | 0.4083 | 1 |
Leishmania major | cytochrome p450-like protein | 0.008 | 0.0952 | 0.0952 |
Echinococcus multilocularis | sex peptide receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | serotonin receptor | 0.0149 | 0.4083 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0278 | 1 | 1 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0149 | 0.4083 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0278 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Brugia malayi | Dopamine receptor protein 1 | 0.0149 | 0.4083 | 0.346 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0149 | 0.4083 | 0.346 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0139 | 0.3631 | 0.8556 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Brugia malayi | AKH receptor | 0.0149 | 0.4083 | 0.346 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0149 | 0.4083 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0149 | 0.4083 | 1 |
Onchocerca volvulus | 0.0149 | 0.4083 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus granulosus | g protein coupled receptor | 0.0149 | 0.4083 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0149 | 0.4083 | 1 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0136 | 0.3524 | 0.3524 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0149 | 0.4083 | 1 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Brugia malayi | sulfakinin receptor protein | 0.0149 | 0.4083 | 0.346 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0278 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.4083 | 0.3477 |
Echinococcus granulosus | somatostatin receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | 6 phosphofructo 2 kinase:fructose 2 | 0.0139 | 0.3631 | 0.8556 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.008 | 0.0952 | 0.5 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0149 | 0.4083 | 0.346 |
Echinococcus multilocularis | neuropeptide receptor | 0.0149 | 0.4083 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0149 | 0.4083 | 1 |
Brugia malayi | hypothetical protein | 0.0149 | 0.4083 | 0.346 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | 0 mg kg-1 | Ataxia or neurological deficit was measured as horizontal screen test(HS) in mice at a dose of 160 mg/kg; NA means Not active | ChEMBL. | 3656350 |
ED50 (functional) | = 170 mg kg-1 | Antagonistic activity against MES (Maximal Elecroshock)-induced seizures after oral administration to mice | ChEMBL. | 3656350 |
ED50 (functional) | = 170 mg kg-1 | Antagonistic activity against MES (Maximal Elecroshock)-induced seizures after oral administration to mice | ChEMBL. | 3656350 |
TPE (functional) | = 2 hr | Time taken for peak anticonvulsant effect(TPE) was measured by oral administration to mice | ChEMBL. | 3656350 |
TPE (functional) | = 2 hr | Time taken for peak anticonvulsant effect(TPE) was measured by oral administration to mice | ChEMBL. | 3656350 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.