Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | beta-lactamase | 0.0081 | 0.112 | 0.1913 |
Brugia malayi | Dopamine receptor protein 1 | 0.0165 | 0.2856 | 0.4879 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.2622 | 0.4479 |
Onchocerca volvulus | 0.0165 | 0.2856 | 1 | |
Onchocerca volvulus | 0.0165 | 0.2856 | 1 | |
Echinococcus granulosus | neuropeptide s receptor | 0.0165 | 0.2856 | 0.9635 |
Onchocerca volvulus | 0.0165 | 0.2856 | 1 | |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0165 | 0.2856 | 0.4879 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.01 | 0.1509 | 0.0822 |
Brugia malayi | neuropeptide F receptor | 0.0165 | 0.2856 | 0.4879 |
Toxoplasma gondii | ABC1 family protein | 0.0081 | 0.112 | 0.7422 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0081 | 0.112 | 0.1913 |
Schistosoma mansoni | biogenic amine receptor | 0.0165 | 0.2856 | 0.9635 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0165 | 0.2856 | 0.4879 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.01 | 0.1509 | 0.0438 |
Brugia malayi | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Brugia malayi | GnHR receptor homolog | 0.0165 | 0.2856 | 0.4879 |
Mycobacterium leprae | Conserved hypothetical protein | 0.01 | 0.1509 | 1 |
Mycobacterium leprae | putative cytochrome p450 | 0.01 | 0.1509 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0081 | 0.112 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0165 | 0.2856 | 0.4879 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0312 | 0.5853 | 1 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0312 | 0.5853 | 1 |
Brugia malayi | ORL1-like opioid receptor | 0.0165 | 0.2856 | 0.4879 |
Onchocerca volvulus | 0.0165 | 0.2856 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.112 | 0.1913 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | beta-lactamase | 0.0081 | 0.112 | 0.1913 |
Echinococcus granulosus | muscleblind protein | 0.0154 | 0.2622 | 0.8846 |
Schistosoma mansoni | amine GPCR | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0165 | 0.2856 | 0.9635 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.01 | 0.1509 | 0.0438 |
Echinococcus granulosus | orexin receptor type 2 | 0.0165 | 0.2856 | 0.9635 |
Echinococcus granulosus | neuropeptide receptor | 0.0165 | 0.2856 | 0.9635 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0165 | 0.2856 | 0.4879 |
Schistosoma mansoni | amine GPCR | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.01 | 0.1509 | 0.0438 |
Schistosoma mansoni | biogenic amine receptor | 0.0165 | 0.2856 | 0.9635 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0081 | 0.112 | 0.1913 |
Brugia malayi | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Echinococcus multilocularis | somatostatin receptor | 0.0165 | 0.2856 | 0.9635 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.01 | 0.1509 | 0.0822 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0081 | 0.112 | 0.3778 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0081 | 0.112 | 0.3778 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | amine GPCR | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0081 | 0.112 | 0.3778 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0165 | 0.2856 | 0.4879 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | neuropeptide receptor | 0.0165 | 0.2856 | 0.9635 |
Echinococcus granulosus | g-protein coupled receptor | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | neuropeptide receptor | 0.0165 | 0.2856 | 0.9635 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0165 | 0.2856 | 0.9635 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0165 | 0.2856 | 0.9635 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.01 | 0.1509 | 0.0438 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0081 | 0.112 | 0.3778 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0102 | 0.1566 | 0.2675 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.2622 | 0.4479 |
Brugia malayi | Muscleblind-like protein | 0.0154 | 0.2622 | 0.4479 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Echinococcus multilocularis | g protein coupled receptor | 0.0165 | 0.2856 | 0.9635 |
Onchocerca volvulus | 0.0165 | 0.2856 | 1 | |
Onchocerca volvulus | 0.0165 | 0.2856 | 1 | |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Brugia malayi | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0165 | 0.2856 | 0.4879 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0165 | 0.2856 | 0.4879 |
Echinococcus granulosus | sex peptide receptor | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | fmrfamide receptor | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0312 | 0.5853 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Echinococcus multilocularis | allatostatin A receptor | 0.0165 | 0.2856 | 0.9635 |
Brugia malayi | Serotonin receptor | 0.0165 | 0.2856 | 0.4879 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0165 | 0.2856 | 0.9635 |
Brugia malayi | neuropeptide F receptor | 0.0165 | 0.2856 | 0.4879 |
Echinococcus multilocularis | sex peptide receptor | 0.0165 | 0.2856 | 0.9635 |
Onchocerca volvulus | 0.0165 | 0.2856 | 1 | |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | cytochrome P450 | 0.01 | 0.1509 | 0.5091 |
Brugia malayi | G-protein coupled receptor | 0.0165 | 0.2856 | 0.4879 |
Brugia malayi | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Echinococcus multilocularis | g protein coupled receptor | 0.0165 | 0.2856 | 0.9635 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0081 | 0.112 | 0.1913 |
Schistosoma mansoni | neuropeptide receptor | 0.0165 | 0.2856 | 0.9635 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0165 | 0.2856 | 1 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0165 | 0.2856 | 0.4879 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | opsin-like receptor | 0.0165 | 0.2856 | 0.9635 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0165 | 0.2856 | 0.4879 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0165 | 0.2856 | 0.9635 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.01 | 0.1509 | 0.0438 |
Echinococcus granulosus | neuropeptide receptor | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.112 | 0.1913 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.01 | 0.1509 | 0.2578 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.01 | 0.1509 | 0.0438 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0165 | 0.2856 | 0.9635 |
Brugia malayi | G protein-coupled receptor | 0.0165 | 0.2856 | 0.4879 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0165 | 0.2856 | 0.9635 |
Brugia malayi | G-protein coupled receptor | 0.0165 | 0.2856 | 0.4879 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.01 | 0.1509 | 0.0822 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.01 | 0.1509 | 0.0438 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Onchocerca volvulus | 0.0165 | 0.2856 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.01 | 0.1509 | 0.0438 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Onchocerca volvulus | 0.0165 | 0.2856 | 1 | |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0081 | 0.112 | 1 |
Brugia malayi | Dopamine receptor protein 2 | 0.0165 | 0.2856 | 0.4879 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0102 | 0.1566 | 0.5282 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.2964 | 1 |
Schistosoma mansoni | myosin xvIII | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Brugia malayi | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0165 | 0.2856 | 0.9635 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.01 | 0.1509 | 0.0822 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0165 | 0.2856 | 0.9635 |
Giardia lamblia | Beta tubulin | 0.0026 | 0 | 0.5 |
Echinococcus granulosus | allatostatin A receptor | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Brugia malayi | cytochrome P450 | 0.01 | 0.1509 | 0.2578 |
Entamoeba histolytica | tubulin family protein | 0.0026 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.01 | 0.1509 | 0.0438 |
Echinococcus multilocularis | serotonin receptor | 0.0165 | 0.2856 | 0.9635 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.01 | 0.1509 | 0.0822 |
Brugia malayi | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Plasmodium vivax | hypothetical protein, conserved | 0.0081 | 0.112 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Brugia malayi | RE15519p | 0.0165 | 0.2856 | 0.4879 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0165 | 0.2856 | 0.9635 |
Echinococcus granulosus | g protein coupled receptor | 0.0165 | 0.2856 | 0.9635 |
Giardia lamblia | Beta tubulin | 0.0026 | 0 | 0.5 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0165 | 0.2856 | 0.9635 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0165 | 0.2856 | 0.9635 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0165 | 0.2856 | 0.4879 |
Echinococcus multilocularis | muscleblind protein | 0.0154 | 0.2622 | 0.8846 |
Brugia malayi | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0081 | 0.112 | 1 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0165 | 0.2856 | 0.9635 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.01 | 0.1509 | 1 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.01 | 0.1509 | 0.2578 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Echinococcus multilocularis | serotonin receptor | 0.0165 | 0.2856 | 0.9635 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.01 | 0.1509 | 0.0438 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0165 | 0.2856 | 0.4879 |
Echinococcus multilocularis | 0.01 | 0.1509 | 0.5091 | |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0165 | 0.2856 | 0.9635 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0102 | 0.1566 | 0.5282 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.01 | 0.1509 | 0.0822 |
Brugia malayi | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.01 | 0.1509 | 0.0822 |
Loa Loa (eye worm) | cytochrome P450 | 0.01 | 0.1509 | 0.2578 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0165 | 0.2856 | 0.4879 |
Plasmodium falciparum | tubulin beta chain | 0.0026 | 0 | 0.5 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0165 | 0.2856 | 0.9635 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | histamine h1 receptor | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0081 | 0.112 | 0.1913 |
Trichomonas vaginalis | esterase, putative | 0.0081 | 0.112 | 1 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | amine GPCR | 0.0165 | 0.2856 | 0.9635 |
Onchocerca volvulus | 0.0165 | 0.2856 | 1 | |
Brugia malayi | Dopamine receptor | 0.0165 | 0.2856 | 0.4879 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0165 | 0.2856 | 0.4879 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0165 | 0.2856 | 0.4879 |
Echinococcus granulosus | hypothetical protein | 0.0165 | 0.2856 | 0.9635 |
Brugia malayi | Melatonin receptor type 1A | 0.0165 | 0.2856 | 0.4879 |
Brugia malayi | AKH receptor | 0.0165 | 0.2856 | 0.4879 |
Leishmania major | hypothetical protein, conserved | 0.0081 | 0.112 | 0.1913 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0165 | 0.2856 | 0.9635 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.01 | 0.1509 | 0.0822 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0312 | 0.5853 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0312 | 0.5853 | 1 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0165 | 0.2856 | 1 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.01 | 0.1509 | 0.0822 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | opsin-like receptor | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0165 | 0.2856 | 0.4879 |
Onchocerca volvulus | 0.0165 | 0.2856 | 1 | |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.01 | 0.1509 | 0.0822 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0212 | 0.3816 | 0.652 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0165 | 0.2856 | 0.4879 |
Giardia lamblia | Beta tubulin | 0.0026 | 0 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | opsin-like receptor | 0.0165 | 0.2856 | 0.9635 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.01 | 0.1509 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.01 | 0.1509 | 0.0438 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.01 | 0.1509 | 0.0438 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0165 | 0.2856 | 0.4879 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0102 | 0.1566 | 0.5282 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Onchocerca volvulus | 0.0165 | 0.2856 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.01 | 0.1509 | 0.0438 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.01 | 0.1509 | 0.2578 |
Brugia malayi | sulfakinin receptor protein | 0.0165 | 0.2856 | 0.4879 |
Brugia malayi | Cytochrome P450 family protein | 0.01 | 0.1509 | 0.2578 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.112 | 0.1913 |
Brugia malayi | beta-lactamase family protein | 0.0081 | 0.112 | 0.1913 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.2964 | 1 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0165 | 0.2856 | 0.4879 |
Brugia malayi | larval opioid receptor | 0.0165 | 0.2856 | 0.4879 |
Echinococcus granulosus | g protein coupled receptor | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Brugia malayi | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.1509 | 0.5091 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0165 | 0.2856 | 0.9635 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.01 | 0.1509 | 0.0822 |
Onchocerca volvulus | 0.0165 | 0.2856 | 1 | |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.01 | 0.1509 | 0.0822 |
Leishmania major | cytochrome p450-like protein | 0.0312 | 0.5853 | 1 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | adenoreceptor | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Echinococcus granulosus | serotonin receptor | 0.0165 | 0.2856 | 0.9635 |
Trypanosoma brucei | cytochrome P450, putative | 0.0312 | 0.5853 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0312 | 0.5853 | 1 |
Echinococcus granulosus | geminin | 0.0171 | 0.2964 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0102 | 0.1566 | 0.5282 |
Echinococcus multilocularis | geminin | 0.0171 | 0.2964 | 1 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.01 | 0.1509 | 0.2578 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Onchocerca volvulus | 0.0165 | 0.2856 | 1 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0081 | 0.112 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0165 | 0.2856 | 0.9635 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | fmrfamide receptor | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0154 | 0.2622 | 0.8846 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.01 | 0.1509 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0165 | 0.2856 | 0.9635 |
Onchocerca volvulus | 0.0165 | 0.2856 | 1 | |
Onchocerca volvulus | 0.0165 | 0.2856 | 1 | |
Brugia malayi | Cytochrome P450 family protein | 0.0137 | 0.2269 | 0.3877 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.01 | 0.1509 | 0.0438 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0165 | 0.2856 | 0.9635 |
Leishmania major | cytochrome p450-like protein | 0.01 | 0.1509 | 0.2578 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0165 | 0.2856 | 0.9635 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0081 | 0.112 | 0.1913 |
Echinococcus multilocularis | g protein coupled receptor | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0137 | 0.2269 | 0.3877 |
Echinococcus granulosus | somatostatin receptor | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0312 | 0.5853 | 1 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0165 | 0.2856 | 0.9635 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.01 | 0.1509 | 0.0438 |
Brugia malayi | Serotonin receptor | 0.0165 | 0.2856 | 0.4879 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0102 | 0.1566 | 0.5282 |
Brugia malayi | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Leishmania major | cytochrome p450-like protein | 0.01 | 0.1509 | 0.2578 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0165 | 0.2856 | 0.4879 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0165 | 0.2856 | 0.9635 |
Brugia malayi | putative neuropeptide receptor | 0.0165 | 0.2856 | 0.4879 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0102 | 0.1566 | 0.2675 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.01 | 0.1509 | 0.0822 |
Echinococcus granulosus | fmrfamide receptor | 0.0165 | 0.2856 | 0.9635 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.01 | 0.1509 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Echinococcus multilocularis | neuropeptide receptor | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0165 | 0.2856 | 0.9635 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0102 | 0.1566 | 0.5282 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.01 | 0.1509 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Echinococcus multilocularis | neuropeptide receptor | 0.0165 | 0.2856 | 0.9635 |
Echinococcus granulosus | g protein coupled receptor | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.112 | 0.1913 |
Onchocerca volvulus | 0.0165 | 0.2856 | 1 | |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.01 | 0.1509 | 0.0822 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.01 | 0.1509 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0081 | 0.112 | 1 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.01 | 0.1509 | 0.0822 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0165 | 0.2856 | 0.9635 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.01 | 0.1509 | 0.2578 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0165 | 0.2856 | 0.9635 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.01 | 0.1509 | 0.5091 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.01 | 0.1509 | 0.0438 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.01 | 0.1509 | 0.0438 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0165 | 0.2856 | 0.9635 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0165 | 0.2856 | 0.4879 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Brugia malayi | Cytochrome P450 family protein | 0.0312 | 0.5853 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.2856 | 0.9635 |
Schistosoma mansoni | neuropeptide receptor | 0.0165 | 0.2856 | 0.9635 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.01 | 0.1509 | 0.0822 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0165 | 0.2856 | 0.9635 |
Entamoeba histolytica | tubulin family protein | 0.0026 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.112 | 0.1913 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0102 | 0.1566 | 0.5282 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.112 | 0.1913 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0165 | 0.2856 | 0.9635 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.2856 | 0.4879 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.01 | 0.1509 | 0.0438 |
Brugia malayi | beta-lactamase family protein | 0.0081 | 0.112 | 0.1913 |
Schistosoma mansoni | amine GPCR | 0.0165 | 0.2856 | 0.9635 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.01 | 0.1509 | 0.0438 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0165 | 0.2856 | 0.9635 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Efficacy (ADMET) | = 0.03 | Efficacy was determined as ratio of Vmax to that of Km | ChEMBL. | 8648611 |
Km app (ADMET) | = 1150 uM | Catalytical constant (app Km)of the compound was evaluated at pH 7.5 | ChEMBL. | 8648611 |
pKa (ADMET) | = 9.5 | Catalytical constant of the compound was evaluated | ChEMBL. | 8648611 |
Vmax (ADMET) | = 40 uM min-1 (mg of protein)-1 | Catalytical constant (Vmax) of the compound was evaluated | ChEMBL. | 8648611 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.