Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | somatostatin receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0187 | 0 | 0.5 |
Onchocerca volvulus | 0.0187 | 0 | 0.5 | |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0187 | 0 | 0.5 |
Trypanosoma brucei | cytochrome P450, putative | 0.0295 | 1 | 0.5 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | g protein coupled receptor | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | g protein coupled receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | fmrfamide receptor | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0187 | 0 | 0.5 |
Onchocerca volvulus | 0.0187 | 0 | 0.5 | |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0187 | 0 | 0.5 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0295 | 1 | 0.5 |
Schistosoma mansoni | opsin-like receptor | 0.0187 | 0 | 0.5 |
Onchocerca volvulus | 0.0187 | 0 | 0.5 | |
Echinococcus granulosus | sex peptide receptor | 0.0187 | 0 | 0.5 |
Onchocerca volvulus | 0.0187 | 0 | 0.5 | |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | orexin receptor type 2 | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | allatostatin A receptor | 0.0187 | 0 | 0.5 |
Onchocerca volvulus | 0.0187 | 0 | 0.5 | |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0187 | 0 | 0.5 |
Onchocerca volvulus | 0.0187 | 0 | 0.5 | |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0187 | 0 | 0.5 |
Onchocerca volvulus | 0.0187 | 0 | 0.5 | |
Schistosoma mansoni | amine GPCR | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | serotonin receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | neuropeptide receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | neuropeptide receptor | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0187 | 0 | 0.5 |
Onchocerca volvulus | 0.0187 | 0 | 0.5 | |
Schistosoma mansoni | amine GPCR | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | allatostatin A receptor | 0.0187 | 0 | 0.5 |
Onchocerca volvulus | 0.0187 | 0 | 0.5 | |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | biogenic amine receptor | 0.0187 | 0 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0295 | 1 | 0.5 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | neuropeptide s receptor | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | g-protein coupled receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | g protein coupled receptor | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0187 | 0 | 0.5 |
Onchocerca volvulus | 0.0187 | 0 | 0.5 | |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | myosin xvIII | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | biogenic amine receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | serotonin receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | opsin-like receptor | 0.0187 | 0 | 0.5 |
Onchocerca volvulus | 0.0187 | 0 | 0.5 | |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | biogenic amine receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | g protein coupled receptor | 0.0187 | 0 | 0.5 |
Leishmania major | cytochrome p450-like protein | 0.0295 | 1 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0295 | 1 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0295 | 1 | 0.5 |
Brugia malayi | Cytochrome P450 family protein | 0.0295 | 1 | 1 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | fmrfamide receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | neuropeptide receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | opsin-like receptor | 0.0187 | 0 | 0.5 |
Onchocerca volvulus | 0.0187 | 0 | 0.5 | |
Echinococcus granulosus | g protein coupled receptor | 0.0187 | 0 | 0.5 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0187 | 0 | 0.5 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0187 | 0 | 0.5 |
Onchocerca volvulus | 0.0187 | 0 | 0.5 | |
Schistosoma mansoni | histamine h1 receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | somatostatin receptor | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | neuropeptide receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | fmrfamide receptor | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0187 | 0 | 0.5 |
Echinococcus granulosus | g protein coupled receptor | 0.0187 | 0 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0295 | 1 | 1 |
Echinococcus multilocularis | serotonin receptor | 0.0187 | 0 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0187 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.1264 | 0.1264 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0187 | 0 | 0.5 |
Onchocerca volvulus | 0.0187 | 0 | 0.5 | |
Echinococcus multilocularis | sex peptide receptor | 0.0187 | 0 | 0.5 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0295 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0187 | 0 | 0.5 |
Onchocerca volvulus | 0.0187 | 0 | 0.5 | |
Onchocerca volvulus | 0.0187 | 0 | 0.5 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0187 | 0 | 0.5 |
Schistosoma mansoni | adenoreceptor | 0.0187 | 0 | 0.5 |
Onchocerca volvulus | 0.0187 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
pKa | = 6.8 | pKa value of the compound was determined | ChEMBL. | 12729653 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.