Detailed information for compound 690751

Basic information

Technical information
  • TDR Targets ID: 690751
  • Name: N-[2-(4-dimethylaminophenyl)-2-morpholin-4-yl ethyl]-N'-(2-ethylphenyl)oxamide
  • MW: 424.536 | Formula: C24H32N4O3
  • H donors: 2 H acceptors: 2 LogP: 2.92 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1ccccc1NC(=O)C(=O)NCC(c1ccc(cc1)N(C)C)N1CCOCC1
  • InChi: 1S/C24H32N4O3/c1-4-18-7-5-6-8-21(18)26-24(30)23(29)25-17-22(28-13-15-31-16-14-28)19-9-11-20(12-10-19)27(2)3/h5-12,22H,4,13-17H2,1-3H3,(H,25,29)(H,26,30)
  • InChiKey: UAGQGZRJMISQQM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[2-(4-dimethylaminophenyl)-2-morpholino-ethyl]-N'-(2-ethylphenyl)oxamide
  • N-[2-(4-dimethylaminophenyl)-2-morpholinoethyl]-N'-(2-ethylphenyl)oxamide
  • N-[2-(4-dimethylaminophenyl)-2-morpholin-4-yl-ethyl]-N'-(2-ethylphenyl)ethanediamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi Heat shock protein 83, putative 0.0092 0.1243 0.2687
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0068 0.0125
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0072 0.0155
Schistosoma mansoni coup transcription factor 0.0028 0.0149 0.0248
Echinococcus granulosus PHD finger protein rhinoceros 0.0059 0.0674 0.1121
Toxoplasma gondii fructose-bisphosphate aldolase, putative 0.0092 0.1235 0.2203
Schistosoma mansoni fatty-acid amide hydrolase 0.0025 0.0104 0.0173
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0069 0.0841 0.1778
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0145 0.2124 0.4509
Schistosoma mansoni hypothetical protein 0.0023 0.0068 0.0113
Schistosoma mansoni heat shock protein 0.0092 0.1243 0.2068
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0009 0.0016
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0045 0.044 0.0732
Loa Loa (eye worm) steroid hormone receptor 0.0028 0.0149 0.0149
Plasmodium vivax heat shock protein 90, putative 0.0061 0.0718 0.128
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.4685 1
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0125 0.027
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0069 0.0841 0.1818
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0033 0.0071
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0009 0.002
Echinococcus granulosus flap endonuclease 1 0.0026 0.0125 0.0208
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0685 0.1222
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2581 0.5501
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0145 0.2124 0.4583
Brugia malayi Bromodomain containing protein 0.0059 0.0674 0.0674
Loa Loa (eye worm) glutaminase 0.0277 0.4361 0.4361
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0623 0.1311
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.019 0.2897 0.6205
Loa Loa (eye worm) glutathione reductase 0.0083 0.1089 0.1089
Loa Loa (eye worm) heat shock protein 90 0.0092 0.1243 0.1243
Entamoeba histolytica hypothetical protein 0.0038 0.0322 0.0668
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0091 0.0196
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0059 0.0674 0.1121
Plasmodium falciparum heat shock protein 90, putative 0.0054 0.0588 0.1049
Plasmodium falciparum fructose-bisphosphate aldolase 0.0092 0.1235 0.2203
Entamoeba histolytica heat shock protein 90, putative 0.0092 0.1243 0.2638
Mycobacterium leprae PROBABLE AMIDASE AMIC (AMINOHYDROLASE) 0.0025 0.0104 0.0071
Onchocerca volvulus 0.0028 0.0149 0.023
Mycobacterium leprae PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) 0.0025 0.0104 0.0071
Leishmania major heat shock protein 83-1 0.0092 0.1243 0.2687
Entamoeba histolytica hypothetical protein 0.0023 0.0068 0.0125
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0047 0.0481 0.0481
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0069 0.0841 0.1818
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0009 0.002
Schistosoma mansoni kinase 0.0097 0.1317 0.2192
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0007 0.0007
Entamoeba histolytica hypothetical protein 0.0038 0.0322 0.0668
Trypanosoma brucei heat shock protein, putative 0.0092 0.1243 0.2687
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0091 0.0196
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0149 0.0149
Trypanosoma cruzi heat shock protein 85, putative 0.0092 0.1243 0.2687
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0087 0.1147 0.2464
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0068 0.0125
Echinococcus granulosus fatty acid amide hydrolase 1 0.0208 0.3204 0.5332
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0292 0.4624 0.987
Schistosoma mansoni amidase 0.0208 0.3204 0.5332
Schistosoma mansoni heat shock protein 0.0092 0.1243 0.2068
Loa Loa (eye worm) hypothetical protein 0.0028 0.0149 0.0149
Loa Loa (eye worm) glutaminase 2 0.0277 0.4361 0.4361
Giardia lamblia Grp94/Hsp90 0.0087 0.1147 0.2432
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0092 0.1235 0.2055
Onchocerca volvulus Serine\/threonine kinase homolog 0.0191 0.2903 0.8015
Loa Loa (eye worm) hypothetical protein 0.0023 0.0068 0.0068
Schistosoma mansoni hypothetical protein 0.0032 0.0217 0.0361
Echinococcus multilocularis fructose bisphosphate aldolase class I 0.0092 0.1235 0.2055
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0068 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0292 0.4624 0.987
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0023 0.0068 0.0121
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0028 0.0149 0.0248
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0028 0.0149 0.0248
Echinococcus granulosus pyruvate kinase 0.0033 0.0232 0.0386
Loa Loa (eye worm) thioredoxin reductase 0.0083 0.1089 0.1089
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0232 0.0463
Mycobacterium tuberculosis Probable amidase AmiB2 (aminohydrolase) 0.0025 0.0104 0.0205
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.138 0.138
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0023 0.0068 0.0113
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0009 0.0016
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0091 0.0151
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0067 0.0816 0.1726
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0232 0.0232
Echinococcus granulosus fatty acid amide hydrolase 1 0.0025 0.0104 0.0173
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0069 0.0841 0.1818
Mycobacterium ulcerans hypothetical protein 0.0024 0.0085 0.0164
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0087 0.1147 0.2361
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.3205 0.6931
Mycobacterium ulcerans lysophospholipase 0.0292 0.4624 1
Leishmania major trypanothione reductase 0.0083 0.1089 0.2356
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0292 0.4624 0.987
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0009 0.0016
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0069 0.0841 0.1818
Schistosoma mansoni hypothetical protein 0.0342 0.5462 0.909
Schistosoma mansoni chromobox protein 0.0023 0.0068 0.0113
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0021 0.0039 0.0084
Trichomonas vaginalis heat shock protein, putative 0.0067 0.0814 0.1721
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0029 0.0168 0.061
Loa Loa (eye worm) hypothetical protein 0.0023 0.0068 0.0068
Brugia malayi Heterochromatin protein 1 0.0141 0.2057 0.2057
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0068 0.0125
Echinococcus multilocularis FTZ F1 alpha 0.0028 0.0149 0.0248
Trypanosoma cruzi heat shock protein 90, putative 0.0079 0.1017 0.2199
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0685 0.114
Schistosoma mansoni hypothetical protein 0.0038 0.0322 0.0535
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0292 0.4624 0.987
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.0069 0.0841 0.1608
Brugia malayi glutaminase DH11.1 0.0277 0.4361 0.4361
Trichomonas vaginalis mercuric reductase, putative 0.0029 0.0168 0.0339
Echinococcus granulosus jumonji domain containing protein 0.0082 0.1064 0.177
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0061 0.0718 0.1837
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0674 0.1202
Loa Loa (eye worm) hypothetical protein 0.0059 0.0674 0.0674
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0025 0.0104 0.0173
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0028 0.0149 0.0149
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0232 0.0232
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0028 0.0149 0.0149
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0029 0.0168 0.0299
Onchocerca volvulus 0.0232 0.3605 1
Trypanosoma cruzi amidase, putative 0.0025 0.0104 0.0225
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0125 0.0247
Trypanosoma brucei heat shock protein, putative 0.0092 0.1243 0.2687
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0069 0.0841 0.1399
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0092 0.1235 0.2055
Plasmodium vivax fructose 1,6-bisphosphate aldolase, putative 0.0092 0.1235 0.2203
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0091 0.0151
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0085 0.0184
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0174 0.0289
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.2903 0.6188
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0009 0.002
Trypanosoma cruzi heat shock protein 85, putative 0.0092 0.1243 0.2687
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0022 0.0037
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0072 0.0133
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0021 0.0039 0.0084
Schistosoma mansoni pyruvate kinase 0.0033 0.0232 0.0386
Trypanosoma brucei monoglyceride lipase, putative 0.0292 0.4624 1
Schistosoma mansoni endoplasmin 0.0092 0.1243 0.2068
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0023 0.0068 0.0068
Brugia malayi PHD-finger family protein 0.0019 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0032 0.0217 0.0361
Giardia lamblia Heat shock protein HSP 90-alpha 0.0092 0.1243 0.2638
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0029 0.0168 0.0168
Loa Loa (eye worm) fructose-bisphosphate aldolase 2 0.0092 0.1235 0.1235
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0685 0.114
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0023 0.0068 0.0121
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.0069 0.0841 0.1818
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0029 0.0168 0.0299
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0021 0.0039 0.0084
Brugia malayi nuclear receptor NHR-88 0.0028 0.0149 0.0149
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0009 0.002
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0029 0.0168 0.0363
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0068 0.0125
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0168 0.0363
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0068 0.0125
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0292 0.4624 0.987
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.002
Leishmania major DNA polymerase kappa, putative 0.002 0.0009 0.002
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0023 0.0068 0.0113
Schistosoma mansoni heat shock protein 0.0061 0.0718 0.1195
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0125 0.0223
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0072 0.0133
Plasmodium falciparum glutamyl-tRNA(Gln) amidotransferase subunit A 0.0025 0.0104 0.0186
Mycobacterium ulcerans aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0025 0.0104 0.0205
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0009 0.002
Trypanosoma brucei Heat shock protein 83, putative 0.0092 0.1243 0.2687
Plasmodium vivax glutathione reductase, putative 0.0083 0.1089 0.1944
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0007 0.0012
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0842 0.0842
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0028 0.0149 0.0248
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0029 0.0168 0.0299
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0069 0.0841 0.1778
Loa Loa (eye worm) heat shock protein 75 0.0061 0.0718 0.0718
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0024 0.0085 0.0161
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0028 0.0149 0.0149
Echinococcus multilocularis chromobox protein 1 0.0141 0.2057 0.3423
Schistosoma mansoni retinoic acid receptor RXR 0.0028 0.0149 0.0248
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0883 0.147
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0125 0.027
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.019 0.2897 0.6257
Echinococcus granulosus Chromobox protein 3 0.0023 0.0068 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.1012 0.2144
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0007 0.0012
Entamoeba histolytica hypothetical protein 0.0023 0.0068 0.0125
Brugia malayi AF-10 protein 0.0019 0.0004 0.0004
Echinococcus granulosus FTZ F1 alpha 0.0028 0.0149 0.0248
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0028 0.0149 0.0248
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0232 0.0476
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0029 0.0168 0.0363
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0322 0.0535
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0069 0.0841 0.1818
Leishmania major heat shock protein 83-1 0.0092 0.1243 0.2687
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0292 0.4624 0.987
Mycobacterium ulcerans amidase 0.0025 0.0104 0.0205
Echinococcus granulosus thioredoxin glutathione reductase 0.0084 0.1098 0.1827
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0028 0.0149 0.0149
Echinococcus multilocularis sentrin specific protease 8 0.0067 0.0816 0.1358
Echinococcus granulosus heat shock protein 90 0.0092 0.1243 0.2068
Leishmania major pyruvate kinase 0.0033 0.0232 0.0501
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0168 0.0363
Echinococcus granulosus heat shock protein 90 0.0079 0.1017 0.1692
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.002
Loa Loa (eye worm) hypothetical protein 0.061 1 1
Plasmodium falciparum flap endonuclease 1 0.0026 0.0125 0.0223
Toxoplasma gondii heat shock protein 90, putative 0.0092 0.1243 0.2217
Schistosoma mansoni hypothetical protein 0.0032 0.0217 0.0361
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0232 0.0413
Trypanosoma cruzi heat shock protein 90, putative 0.0092 0.1243 0.2687
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0029 0.0168 0.0299
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0208 0.3204 0.5332
Echinococcus granulosus Chromo domain 0.0023 0.0068 0.0113
Onchocerca volvulus 0.0023 0.0072 0.0011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0068 0.0068
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0069 0.0841 0.1399
Echinococcus multilocularis Chromo domain 0.0023 0.0068 0.0113
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0092 0.1235 0.267
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0168 0.0363
Loa Loa (eye worm) Ulp1 protease 0.0067 0.0816 0.0816
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.002
Treponema pallidum heat shock protein 90 0.0087 0.1147 0.2276
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0052 0.0563 0.0937
Brugia malayi fructose-bisphosphate aldolase 1 0.0092 0.1235 0.1235
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.4102 0.8754
Mycobacterium ulcerans heat shock protein 90 0.0087 0.1147 0.2464
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0029 0.0168 0.0363
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0067 0.0816 0.0816
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0004 0.0009
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.0069 0.0841 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0029 0.0168 0.061
Brugia malayi Amidase family protein 0.0025 0.0104 0.0104
Echinococcus multilocularis expressed protein 0.0366 0.5865 0.9761
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0072 0.0135
Loa Loa (eye worm) hypothetical protein 0.0208 0.3204 0.3204
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0009
Echinococcus multilocularis Chromobox protein 3 0.0023 0.0068 0.0113
Mycobacterium ulcerans amidase 0.0025 0.0104 0.0205
Mycobacterium ulcerans glutaminase 0.0277 0.4361 0.943
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0068 0.0125
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.002
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0028 0.0149 0.0149
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0028 0.0149 0.0149
Echinococcus granulosus chromobox protein 2 0.0023 0.0068 0.0113
Onchocerca volvulus Glucosylceramidase homolog 0.0172 0.2581 0.7106
Mycobacterium tuberculosis Probable amidase AmiC (aminohydrolase) 0.0025 0.0104 0.0205
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0028 0.0149 0.0248
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0085 0.0164
Plasmodium vivax heat shock protein 86, putative 0.0092 0.1243 0.2217
Treponema pallidum fructose-bisphosphate aldolase 0.0296 0.4685 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0071 0.0883 0.147
Mycobacterium ulcerans hypothetical protein 0.0024 0.0085 0.0164
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0292 0.4624 0.987
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0262 0.4102 0.4102
Mycobacterium ulcerans amidase 0.0025 0.0104 0.0205
Mycobacterium tuberculosis Probable amidase AmiA2 (aminohydrolase) 0.0025 0.0104 0.0205
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.0045 0.0439 0.095
Echinococcus granulosus sentrin specific protease 8 0.0067 0.0816 0.1358
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0072 0.0135
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0022 0.0022
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0685 0.114
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0232 0.0501
Schistosoma mansoni glutamyl-tRNA(Gln) amidotransferase subunit A 0.0025 0.0104 0.0173
Brugia malayi serine/threonine-protein kinase plk-2 0.0191 0.2903 0.2903
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.0069 0.0841 0.15
Trypanosoma cruzi trypanothione reductase, putative 0.0029 0.0168 0.0363
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0028 0.0149 0.0149
Echinococcus multilocularis ecdysone induced protein 78C 0.0028 0.0149 0.0248
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0174 0.0289
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.019 0.2897 0.6257
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0029 0.0168 0.0343
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0072 0.0072
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0069 0.0841 0.1778
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0191 0.2903 0.6277
Plasmodium vivax glutamyl-tRNA(Gln) amidotransferase subunit A, putative 0.0025 0.0104 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0028 0.0149 0.0149
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0092 0.1235 0.2055
Plasmodium falciparum heat shock protein 90, putative 0.035 0.5606 1
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0047 0.0481 0.0481
Echinococcus multilocularis dna polymerase kappa 0.002 0.0009 0.0016
Mycobacterium tuberculosis Probable amidase AmiD (acylamidase) (acylase) 0.0025 0.0104 0.0205
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0092 0.1235 0.267
Loa Loa (eye worm) PHD-finger family protein 0.0059 0.0674 0.0674
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0296 0.4685 1
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0067 0.0816 0.1726
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0079 0.1017 0.1692
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0296 0.4685 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0212 0.3256 0.6994
Onchocerca volvulus 0.0023 0.0068 0.000000058595
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0021 0.0039 0.0039
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0029 0.0168 0.0279
Brugia malayi Pre-SET motif family protein 0.0029 0.0174 0.0174
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0068 0.0125
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0168 0.0363
Leishmania major heat shock protein 83-1 0.0092 0.1243 0.2687
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0232 0.0463
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0009 0.002
Loa Loa (eye worm) helicase 0.0023 0.0068 0.0068
Echinococcus granulosus geminin 0.0342 0.5462 0.909
Mycobacterium ulcerans hypothetical protein 0.0023 0.0072 0.0135
Leishmania major heat shock protein 83-1 0.0092 0.1243 0.2687
Leishmania major heat shock protein 83-1 0.0092 0.1243 0.2687
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0029 0.0168 0.0343
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.4102 0.8754
Schistosoma mansoni flap endonuclease-1 0.0024 0.0082 0.0137
Trichomonas vaginalis chromobox protein, putative 0.0085 0.1113 0.236
Loa Loa (eye worm) jmjC domain-containing protein 0.0121 0.1733 0.1733
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0009 0.0009
Brugia malayi SET domain containing protein 0.0024 0.0086 0.0086
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0067 0.0816 0.1358
Plasmodium falciparum glutathione reductase 0.0083 0.1089 0.1944
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0085 0.0164
Plasmodium falciparum thioredoxin reductase 0.0083 0.1089 0.1944
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0217 0.0217
Echinococcus multilocularis CREB binding protein 0.0374 0.6009 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0168 0.0363
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0068 0.0125
Schistosoma mansoni RAR-like nuclear receptor 0.0028 0.0149 0.0248
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0068 0.0125
Echinococcus granulosus peregrin 0.0059 0.0674 0.1121
Loa Loa (eye worm) hypothetical protein 0.0028 0.0149 0.0149
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0069 0.0841 0.1778
Plasmodium falciparum pyruvate kinase 0.0033 0.0232 0.0413
Loa Loa (eye worm) hypothetical protein 0.0101 0.1385 0.1385
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0174 0.0289
Leishmania major heat shock protein 83-1 0.0092 0.1243 0.2687
Schistosoma mansoni hypothetical protein 0.0342 0.5462 0.909
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0125 0.0223
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0145 0.2124 0.4583
Chlamydia trachomatis pyruvate kinase 0.0033 0.0232 0.1733
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0068 0.0125
Trypanosoma brucei heat shock protein, putative 0.0092 0.1243 0.2687
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.2903 0.6188
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0072 0.0135
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0028 0.0149 0.0149
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0069 0.0841 0.1778
Brugia malayi Flap endonuclease-1 0.0026 0.0125 0.0125
Plasmodium vivax endoplasmin, putative 0.0092 0.1243 0.2217
Echinococcus multilocularis glutamyl tRNA(Gln) amidotransferase subunit A 0.0025 0.0104 0.0173
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0069 0.0841 0.1399
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0028 0.0149 0.0149
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0685 0.1482
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0072 0.0135
Brugia malayi Hsp90 protein 0.0061 0.0718 0.0718
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0045 0.044 0.0732
Brugia malayi amidase 0.0208 0.3204 0.3204
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0125 0.0247
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0149 0.0248
Brugia malayi steroid hormone receptor 0.0028 0.0149 0.0149
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0019 0.0004 0.0007
Brugia malayi Pre-SET motif family protein 0.0204 0.3128 0.3128
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0149 0.0248
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.4685 1
Plasmodium vivax heat shock protein, putative 0.035 0.5606 1
Leishmania major hypothetical protein, conserved 0.0025 0.0104 0.0225
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0069 0.0841 0.1778
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0068 0.0125
Schistosoma mansoni thyroid hormone receptor 0.0028 0.0149 0.0248
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0007 0.0012
Echinococcus granulosus CREB binding protein 0.0374 0.6009 1
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0029 0.0168 0.0363
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0092 0.1235 0.2055
Toxoplasma gondii heat shock protein 75, putative 0.0061 0.0718 0.128
Trypanosoma cruzi monoglyceride lipase, putative 0.0292 0.4624 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0149 0.0149
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.0149 0.0248
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0068 0.0125
Plasmodium falciparum endoplasmin, putative 0.0067 0.0814 0.1452
Brugia malayi Associated with TFs and helicases family protein 0.0023 0.0068 0.0068
Giardia lamblia NADH oxidase lateral transfer candidate 0.0029 0.0168 0.0339
Leishmania major monoglyceride lipase, putative 0.0292 0.4624 1
Plasmodium falciparum glutathione reductase 0.0029 0.0168 0.0299
Plasmodium falciparum thioredoxin reductase 0.0029 0.0168 0.0299
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0685 0.1465
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0072 0.0135
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0029 0.0168 0.0279
Trichomonas vaginalis endoplasmin, putative 0.0067 0.0814 0.1721
Brugia malayi Amidase family protein 0.0025 0.0104 0.0104
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0023 0.0068 0.0121
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0045 0.044 0.044
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.4685 1
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0125 0.0125
Trypanosoma cruzi polo-like protein kinase, putative 0.0191 0.2903 0.6277
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0174 0.031
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0092 0.1235 0.2055
Trypanosoma brucei unspecified product 0.002 0.0009 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0068 0.0125
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0024 0.008 0.0018
Echinococcus granulosus dna polymerase eta 0.002 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.0029 0.0174 0.0174
Echinococcus granulosus expressed protein 0.0366 0.5865 0.9761
Trichomonas vaginalis hypothetical protein 0.0023 0.0068 0.0125
Loa Loa (eye worm) hypothetical protein 0.0023 0.0068 0.0068
Echinococcus granulosus ecdysone induced protein 78C 0.0028 0.0149 0.0248
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0009 0.002
Echinococcus multilocularis thyroid hormone receptor alpha 0.0028 0.0149 0.0248
Trypanosoma brucei heat shock protein, putative 0.0092 0.1243 0.2687
Leishmania major hypothetical protein, conserved 0.0208 0.3205 0.6931
Giardia lamblia Fructose-bisphosphate aldolase 0.0296 0.4685 1
Loa Loa (eye worm) hypothetical protein 0.0079 0.1012 0.1012
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0068 0.0125
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0168 0.0363
Schistosoma mansoni chromobox protein 0.0023 0.0068 0.0113
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0061 0.0718 0.1515
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0262 0.4102 0.4102
Mycobacterium tuberculosis Possible lysophospholipase 0.0292 0.4624 1
Plasmodium vivax SET domain protein, putative 0.0029 0.0174 0.031
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0072 0.0155
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0009 0.002
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0061 0.0718 0.1195
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0091 0.0162
Brugia malayi PHD-finger family protein 0.0059 0.0674 0.0674
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0024 0.0079 0.0079
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0068 0.0125
Loa Loa (eye worm) hypothetical protein 0.0028 0.0149 0.0149
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0029 0.0168 0.0343
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0068 0.0125
Trypanosoma brucei heat shock protein 84, putative 0.0061 0.0718 0.1552
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.002
Loa Loa (eye worm) amidase 0.0025 0.0104 0.0104
Trypanosoma brucei monoglyceride lipase, putative 0.0292 0.4624 1
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0292 0.4624 0.987
Trichomonas vaginalis heat shock protein, putative 0.0054 0.0588 0.1237
Onchocerca volvulus 0.0052 0.0563 0.1399
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0168 0.0363
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.3128 0.3128
Plasmodium vivax thioredoxin reductase, putative 0.0083 0.1089 0.1944
Brugia malayi putative amidase 0.0025 0.0104 0.0104
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0232 0.0232
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0064 0.0064
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0125 0.0208
Loa Loa (eye worm) CBP-B 0.0374 0.6009 0.6009
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0024 0.0085 0.0164
Leishmania major heat shock protein 83-1 0.0092 0.1243 0.2687
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0079 0.1012 0.2668
Trypanosoma cruzi heat shock protein 85, putative 0.0092 0.1243 0.2687
Plasmodium falciparum heat shock protein 90 0.0092 0.1243 0.2217
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0068 0.0125
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.2737 0.5835
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0028 0.0149 0.0248
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0004
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0092 0.1235 0.267
Loa Loa (eye worm) endoplasmin 0.0092 0.1243 0.1243
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0232 0.0232
Plasmodium vivax hypothetical protein, conserved 0.0059 0.0674 0.1202
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0028 0.0149 0.0149
Schistosoma mansoni nuclear hormone receptor 0.0028 0.0149 0.0248
Brugia malayi photoreceptor-specific nuclear receptor 0.0028 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0028 0.0149 0.0149
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0028 0.0149 0.0149
Plasmodium falciparum lysophospholipase, putative 0.0292 0.4624 0.8249
Echinococcus multilocularis pyruvate kinase 0.0033 0.0232 0.0386
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.0069 0.0841 0.15
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0028 0.0149 0.0248
Trichomonas vaginalis chromobox protein, putative 0.0141 0.2057 0.4379
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0072 0.0135
Loa Loa (eye worm) hypothetical protein 0.0023 0.0072 0.0072
Leishmania major pyruvate kinase 0.0033 0.0232 0.0501
Leishmania major heat shock protein 83-1 0.0092 0.1243 0.2687
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.4685 1
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0068 0.0125
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.4102 0.8754
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0028 0.0149 0.023
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0024 0.0079 0.015
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0232 0.0501
Leishmania major heat shock protein 83-1 0.0092 0.1243 0.2687
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.4102 0.8754
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0217 0.0361
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0004 0.0007
Entamoeba histolytica serine/threonine protein kinase, putative 0.0191 0.2903 0.6188
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0009 0.002
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0023 0.0068 0.0113
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0072 0.0135
Toxoplasma gondii thioredoxin reductase 0.0083 0.1089 0.1944
Echinococcus granulosus lysine specific demethylase 5A 0.0071 0.0883 0.147
Echinococcus granulosus chromobox protein 1 0.0141 0.2057 0.3423
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0091 0.0174
Brugia malayi M-phase phosphoprotein, mpp8 0.0023 0.0068 0.0068
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0021 0.0038 0.0038
Echinococcus multilocularis heat shock protein 90 0.0092 0.1243 0.2068
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0155 0.0259
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0883 0.147
Toxoplasma gondii NADPH-glutathione reductase 0.0029 0.0168 0.0299
Mycobacterium ulcerans hypothetical protein 0.0292 0.4624 1
Trypanosoma cruzi heat shock protein 85, putative 0.0079 0.1017 0.2199
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0217 0.0361
Mycobacterium ulcerans peptide amidase, GatA 0.0025 0.0104 0.0205
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0067 0.0816 0.1726
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0068 0.0125
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0069 0.0841 0.1399
Schistosoma mansoni chromobox protein 0.0141 0.2057 0.3423
Giardia lamblia Pyruvate kinase 0.0033 0.0232 0.0476
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2581 0.5501
Brugia malayi CHD4 protein 0.0023 0.0068 0.0068
Onchocerca volvulus Bile acid receptor homolog 0.0028 0.0149 0.023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0064 0.0064
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0068 0.0121
Trypanosoma brucei fatty-acid amide hydrolase, putative 0.0025 0.0104 0.0225
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0069 0.0841 0.1818
Brugia malayi jmjC domain containing protein 0.0071 0.0883 0.0883
Echinococcus multilocularis thioredoxin glutathione reductase 0.0084 0.1098 0.1827
Trypanosoma brucei trypanothione reductase 0.0083 0.1089 0.2356
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0069 0.0841 0.1818
Mycobacterium tuberculosis Conserved protein 0.0024 0.0085 0.0164
Trypanosoma brucei polo-like protein kinase 0.0191 0.2903 0.6277
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0021 0.0038 0.0038
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0045 0.0439 0.095
Trichomonas vaginalis chromobox protein, putative 0.0141 0.2057 0.4379
Echinococcus granulosus pyruvate kinase 0.0033 0.0232 0.0386
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0029 0.0168 0.0343
Loa Loa (eye worm) hypothetical protein 0.0101 0.138 0.138
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.2903 0.6188
Schistosoma mansoni jumonji domain containing protein 0.0153 0.2268 0.3774
Loa Loa (eye worm) hypothetical protein 0.0023 0.0068 0.0068
Trypanosoma cruzi polo-like protein kinase, putative 0.0191 0.2903 0.6277
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0322 0.0535
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.2903 0.6188
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0028 0.0149 0.0248
Trypanosoma brucei hypothetical protein, conserved 0.0208 0.3205 0.6931
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.0068 0.0113
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0092 0.1235 0.2055
Leishmania major heat shock protein 83-1 0.0092 0.1243 0.2687
Trypanosoma brucei fructose-bisphosphate aldolase, glycosomal, putative 0.0092 0.1235 0.267
Loa Loa (eye worm) hypothetical protein 0.0028 0.0149 0.0149
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0023 0.0068 0.0113
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0232 0.0463
Echinococcus multilocularis heat shock protein 90 0.0079 0.1017 0.1692
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0168 0.0363
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0029 0.0168 0.0864
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0069 0.0841 0.1778
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0125 0.027
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0067 0.0816 0.1726
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0007 0.0012
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0023 0.0068 0.0121
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0068 0.0125
Plasmodium falciparum phd finger protein, putative 0.0059 0.0674 0.1202
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0072 0.0135
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0374 0.6009 1
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0004 0.0009
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0092 0.1235 0.2203
Brugia malayi TAZ zinc finger family protein 0.0374 0.6009 0.6009
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.2903 0.6188
Leishmania major heat shock protein 83-1 0.0092 0.1243 0.2687
Schistosoma mansoni glutaminase 0.0277 0.4361 0.7258
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.1275 0.2706
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0068 0.0125
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0092 0.1235 0.2055
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0168 0.0363
Brugia malayi fructose-bisphosphate aldolase 2 0.0092 0.1235 0.1235
Brugia malayi hypothetical protein 0.0038 0.0322 0.0322
Echinococcus multilocularis peregrin 0.0059 0.0674 0.1121
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0028 0.0149 0.0149
Echinococcus multilocularis PHD finger protein rhinoceros 0.0059 0.0674 0.1121
Mycobacterium tuberculosis Probable oxidoreductase 0.0212 0.3256 0.7035
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0045 0.0439 0.092
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0028 0.0149 0.0248
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0085 0.0184
Mycobacterium ulcerans amidase 0.0025 0.0104 0.0205
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.002
Echinococcus granulosus glutamyl tRNAGln amidotransferase subunit A 0.0025 0.0104 0.0173
Plasmodium falciparum esterase, putative 0.0292 0.4624 0.8249
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0028 0.0149 0.0149
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0168 0.0363
Echinococcus granulosus chromobox protein 1 0.0141 0.2057 0.3423
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.002
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0023 0.0068 0.0113
Entamoeba histolytica hypothetical protein 0.0024 0.0091 0.0174
Leishmania major heat shock protein 83-1 0.0092 0.1243 0.2687
Brugia malayi Steroid receptor seven-up type 2 0.0028 0.0149 0.0149
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0068 0.0125
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0069 0.0841 0.1399
Trypanosoma brucei heat shock protein, putative 0.0092 0.1243 0.2687
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.138 0.138
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.002
Echinococcus multilocularis jumonji domain containing protein 0.0082 0.1064 0.177
Plasmodium falciparum lysophospholipase, putative 0.0292 0.4624 0.8249
Loa Loa (eye worm) hypothetical protein 0.0023 0.0068 0.0068
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0191 0.2903 0.4831
Brugia malayi chromobox protein homolog 3 0.0079 0.1012 0.1012
Giardia lamblia Heat shock protein HSP 90-alpha 0.0079 0.1017 0.2155
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0174 0.0289
Brugia malayi hypothetical protein 0.0023 0.0068 0.0068
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0007 0.0007
Treponema pallidum NADH oxidase 0.0029 0.0168 0.0139
Trypanosoma brucei heat shock protein 90, putative 0.0092 0.1243 0.2687
Schistosoma mansoni hypothetical protein 0.0032 0.0217 0.0361
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0028 0.0149 0.0149
Plasmodium vivax heterochromatin protein 1, putative 0.0023 0.0068 0.0121
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.0069 0.0841 0.7066
Trichomonas vaginalis chromobox protein, putative 0.0085 0.1113 0.236
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.0045 0.0439 0.095
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0232 0.0413
Trypanosoma brucei heat shock protein, putative 0.0092 0.1243 0.2687
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0019 0.0004 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2581 0.5501
Loa Loa (eye worm) fructose-bisphosphate aldolase 1 0.0092 0.1235 0.1235
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2581 0.5501
Brugia malayi heat shock protein 90 0.0092 0.1243 0.1243
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0072 0.0072
Leishmania major heat shock protein 83-1 0.0092 0.1243 0.2687
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0028 0.0149 0.0248
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0033
Loa Loa (eye worm) jmjC domain-containing protein 0.0071 0.0883 0.0883
Toxoplasma gondii Hsp90 domain-containing protein 0.035 0.5606 1
Echinococcus multilocularis GPCR, family 2 0.0032 0.0217 0.0361
Schistosoma mansoni thyroid hormone receptor 0.0028 0.0149 0.0248
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0069 0.0841 0.1399
Echinococcus multilocularis chromobox protein 2 0.0023 0.0068 0.0113
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0045 0.044 0.0921
Brugia malayi ecdysteroid receptor 0.0028 0.0149 0.0149
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0217 0.0217
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0208 0.3204 0.5332
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0045 0.044 0.0921
Loa Loa (eye worm) CHromoDomain protein family member 0.0023 0.0068 0.0068
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.2903 0.6188
Schistosoma mansoni fatty-acid amide hydrolase 0.0208 0.3204 0.5332
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0212 0.3256 0.7035
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0021 0.0039 0.0084
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.0069 0.0841 0.15
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0024 0.008 0.0153
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0292 0.4624 1
Brugia malayi glutathione reductase 0.0083 0.1089 0.1089
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0023 0.0068 0.0121
Loa Loa (eye worm) hypothetical protein 0.0032 0.0217 0.0217
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0069 0.0841 0.0841
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0068 0.0121
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0685 0.1465
Plasmodium falciparum heterochromatin protein 1 0.0023 0.0068 0.0121
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0028 0.0149 0.0248
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.4685 1
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0064 0.0118
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0087 0.1147 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0685 0.1465
Echinococcus multilocularis pyruvate kinase 0.0033 0.0232 0.0386
Trypanosoma brucei heat shock protein, putative 0.0092 0.1243 0.2687
Leishmania major heat shock protein 83-1 0.0092 0.1243 0.2687
Loa Loa (eye worm) amidase 0.0025 0.0104 0.0104
Plasmodium vivax PST-A protein 0.0292 0.4624 0.8249
Mycobacterium ulcerans amidase 0.0025 0.0104 0.0205
Trichomonas vaginalis set domain proteins, putative 0.0232 0.3605 0.769
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0685 0.1465
Trichomonas vaginalis heat shock protein, putative 0.0087 0.1147 0.2432
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0685 0.114
Schistosoma mansoni endoplasmin 0.0092 0.1243 0.2068
Leishmania major heat shock protein 83-1 0.0092 0.1243 0.2687
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0072 0.0133
Toxoplasma gondii heat shock protein HSP90 0.0092 0.1243 0.2217
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0028 0.0149 0.0248
Echinococcus multilocularis citrate lyase subunit beta protein 0.0024 0.0085 0.0141
Schistosoma mansoni chromobox protein 0.0141 0.2057 0.3423
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0193 0.2938 0.4889
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0069 0.0841 0.1399
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.0149 0.0248
Echinococcus granulosus endoplasmin 0.0087 0.1147 0.1908
Schistosoma mansoni CREB-binding protein 2 0.0374 0.6009 1
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0092 0.1235 0.2055
Schistosoma mansoni hypothetical protein 0.0069 0.0842 0.1401
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0623 0.1311
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0029 0.0168 0.0299
Echinococcus multilocularis geminin 0.0342 0.5462 0.909
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0168 0.0363
Schistosoma mansoni hypothetical protein 0.0019 0.0004 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2581 0.5501
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0068 0.0125
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0061 0.0718 0.1195
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2581 0.5501
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.0004 0.0007
Entamoeba histolytica hypothetical protein 0.0038 0.0322 0.0668
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.0068 0.0113
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.0069 0.0841 0.15
Entamoeba histolytica heat shock protein 90, putative 0.0092 0.1243 0.2638
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0045 0.0439 0.095
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0092 0.1235 0.267
Loa Loa (eye worm) hypothetical protein 0.0023 0.0068 0.0068
Brugia malayi Protein cec-1. 0.0023 0.0068 0.0068
Brugia malayi Endoplasmin precursor 0.0092 0.1243 0.1243
Entamoeba histolytica hypothetical protein 0.0023 0.0068 0.0125
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0125 0.0247
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0232 0.0501
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.138 0.138
Mycobacterium tuberculosis Putative ferredoxin reductase 0.019 0.2897 0.6257
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0217 0.0361
Schistosoma mansoni serine/threonine protein kinase 0.0191 0.2903 0.4831
Schistosoma mansoni DNA polymerase eta 0.002 0.0009 0.0016
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.2581 0.5501
Onchocerca volvulus Protein ultraspiracle homolog 0.0028 0.0149 0.023
Trypanosoma cruzi amidase, putative 0.0025 0.0104 0.0225
Loa Loa (eye worm) hypothetical protein 0.0045 0.044 0.044
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.019 0.2897 0.6257
Trichomonas vaginalis heat shock protein, putative 0.0092 0.1243 0.2638
Mycobacterium tuberculosis Possible amidase (aminohydrolase) 0.0025 0.0104 0.0205
Echinococcus granulosus fructose bisphosphate aldolase class I 0.0092 0.1235 0.2055
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0069 0.0841 0.1818
Leishmania major DNA polymerase eta, putative 0.002 0.0009 0.002
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0322 0.0535
Giardia lamblia Kinase, PLK 0.0191 0.2903 0.6188
Entamoeba histolytica hypothetical protein 0.0038 0.0322 0.0668
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0191 0.2903 0.4831
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0072 0.0155
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.0069 0.0841 0.1802
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0009 0.002
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0009 0.0009
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0045 0.044 0.044
Leishmania major heat shock protein, putative 0.0061 0.0718 0.1552
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0085 0.0184
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0232 0.0482
Onchocerca volvulus Alhambra homolog 0.0059 0.0674 0.1713
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0232 0.0351
Loa Loa (eye worm) hypothetical protein 0.0028 0.0149 0.0149
Echinococcus multilocularis heat shock protein 0.0092 0.1243 0.2068
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0024 0.0085 0.0164
Loa Loa (eye worm) hypothetical protein 0.0069 0.0842 0.0842
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.4685 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0028 0.0149 0.0149
Echinococcus multilocularis chromobox protein 1 0.0141 0.2057 0.3423
Echinococcus granulosus dna polymerase kappa 0.002 0.0009 0.0016
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0232 0.0476
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.4102 0.8754
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0072 0.0072
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0149 0.0248
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0193 0.2938 0.4889
Trichomonas vaginalis Sentrin-specific protease, putative 0.0067 0.0816 0.1726
Mycobacterium tuberculosis Probable dehydrogenase 0.019 0.2897 0.6257
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0068 0.0125
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0028 0.0149 0.0248
Brugia malayi Thioredoxin reductase 0.0083 0.1089 0.1089
Schistosoma mansoni hypothetical protein 0.0059 0.0674 0.1121
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0068 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.1012 0.2144
Mycobacterium tuberculosis Probable reductase 0.019 0.2897 0.6257
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.1275 0.2706
Schistosoma mansoni pyruvate kinase 0.0033 0.0232 0.0386
Echinococcus granulosus CREB binding protein 0.0374 0.6009 1
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.2903 0.6188
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0009 0.0016
Brugia malayi jmjC domain containing protein 0.0193 0.2938 0.2938
Echinococcus multilocularis pyruvate kinase 0.0026 0.0115 0.0192
Echinococcus granulosus fatty acid amide hydrolase 1 0.0208 0.3204 0.5332
Trypanosoma brucei heat shock protein, putative 0.0092 0.1243 0.2687
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0232 0.0232
Echinococcus multilocularis endoplasmin 0.0087 0.1147 0.1908
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.3205 0.6931
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0069 0.0841 0.1399
Trichomonas vaginalis glutaminase, putative 0.0277 0.4361 0.9307
Trichomonas vaginalis conserved hypothetical protein 0.0292 0.4624 0.987
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0174 0.0289
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0674 0.1202
Trypanosoma cruzi trypanothione reductase, putative 0.0083 0.1089 0.2356
Leishmania major fructose-1,6-bisphosphate aldolase 0.0092 0.1235 0.267
Leishmania major heat shock protein 83-1 0.0092 0.1243 0.2687
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0028 0.0149 0.0248
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0091 0.0091
Onchocerca volvulus 0.0062 0.0724 0.1854
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0028 0.0149 0.0149
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0069 0.0841 0.1818
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0232 0.0482
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0069 0.0841 0.1818
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0028 0.0149 0.0149
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0232 0.0501
Trypanosoma cruzi heat shock protein, putative 0.0061 0.0718 0.1552
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0085 0.1113 0.2954
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0174 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0068 0.0125
Trichomonas vaginalis Heterochromatin protein, putative 0.0023 0.0068 0.0125
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0217 0.0361
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0092 0.1235 0.2203
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0069 0.0841 0.1818
Trichomonas vaginalis heat shock protein, putative 0.0087 0.1147 0.2432
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0007 0.0007
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0217 0.0217
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.4685 1
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0023 0.0068 0.0113
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.002
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0069 0.0841 0.1778
Trypanosoma brucei heat shock protein 90, putative 0.0092 0.1243 0.2687
Echinococcus granulosus heat shock protein 0.0092 0.1243 0.2068
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0091 0.0151
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0068 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0028 0.0149 0.0149
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0191 0.2903 0.2903
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0028 0.0149 0.0149
Schistosoma mansoni steroid hormone receptor ad4bp 0.0028 0.0149 0.0248
Loa Loa (eye worm) hypothetical protein 0.0028 0.0149 0.0149
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.0334 0.0721
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0083 0.1089 0.2341
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0072 0.0135
Trichomonas vaginalis heat shock protein, putative 0.0079 0.1017 0.2155
Brugia malayi Valyl-tRNA synthetase 0.0023 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0062 0.0724 0.0724
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0296 0.4685 1
Echinococcus granulosus GPCR family 2 0.0032 0.0217 0.0361
Trichomonas vaginalis glutathione reductase, putative 0.0029 0.0168 0.0339
Loa Loa (eye worm) hypothetical protein 0.0033 0.0232 0.0232
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.2737 0.5835
Echinococcus multilocularis dna polymerase eta 0.002 0.0009 0.0016
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0069 0.0841 0.1778
Brugia malayi nuclear hormone receptor 0.0028 0.0149 0.0149
Leishmania major heat shock protein 83-1 0.0092 0.1243 0.2687
Echinococcus granulosus citrate lyase subunit beta protein 0.0024 0.0085 0.0141
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0029 0.0168 0.0279
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0021 0.0039 0.0084
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0168 0.0363
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0087 0.1147 0.248
Loa Loa (eye worm) heterochromatin protein 1 0.0141 0.2057 0.2057
Plasmodium falciparum lysophospholipase, putative 0.0292 0.4624 0.8249
Giardia lamblia PHD finger protein 15 0.0059 0.0674 0.1421
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0212 0.3256 0.7035
Trypanosoma cruzi hypothetical protein 0.0067 0.0816 0.1765
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0292 0.4624 0.987
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0007 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.4102 0.8754

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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