Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glucosylceramidase, putative | 0.0177 | 0.3893 | 0.6468 |
Schistosoma mansoni | tar DNA-binding protein | 0.0201 | 0.4433 | 0.4433 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.0648 | 0.0578 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0269 | 0.5986 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0447 | 1 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0608 | 0.0608 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0269 | 0.5986 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0067 | 0.1403 | 0.1403 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0269 | 0.5986 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0269 | 0.5986 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0269 | 0.5986 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0269 | 0.5986 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0201 | 0.4433 | 0.7353 |
Echinococcus multilocularis | tar DNA binding protein | 0.0201 | 0.4433 | 0.4391 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0177 | 0.3893 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0201 | 0.4433 | 0.4391 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 0.3893 | 0.3893 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0648 | 0.0648 |
Loa Loa (eye worm) | TAR-binding protein | 0.0201 | 0.4433 | 0.7353 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0118 | 0.0044 |
Echinococcus multilocularis | geminin | 0.0177 | 0.3893 | 0.3847 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.0608 | 0.0835 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0269 | 0.5986 | 1 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0269 | 0.5986 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0177 | 0.3893 | 0.6468 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0118 | 0.0044 |
Schistosoma mansoni | tar DNA-binding protein | 0.0201 | 0.4433 | 0.4433 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0186 | 0.4108 | 0.6831 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 0.3893 | 0.3893 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0201 | 0.4433 | 0.7354 |
Schistosoma mansoni | tar DNA-binding protein | 0.0201 | 0.4433 | 0.4433 |
Echinococcus granulosus | geminin | 0.0177 | 0.3893 | 0.3847 |
Brugia malayi | TAR-binding protein | 0.0201 | 0.4433 | 0.7354 |
Schistosoma mansoni | tar DNA-binding protein | 0.0201 | 0.4433 | 0.4433 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.0608 | 0.0839 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.1242 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0648 | 0.0648 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0177 | 0.3893 | 0.6468 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0177 | 0.3893 | 0.6468 |
Schistosoma mansoni | tar DNA-binding protein | 0.0201 | 0.4433 | 0.4433 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0447 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0177 | 0.3893 | 0.6468 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0177 | 0.3893 | 0.6468 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0186 | 0.4108 | 0.6831 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0177 | 0.3893 | 0.6468 |
Loa Loa (eye worm) | RNA binding protein | 0.0201 | 0.4433 | 0.7353 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.0648 | 0.0578 |
Brugia malayi | RNA binding protein | 0.0201 | 0.4433 | 0.7354 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0074 | 0.0074 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.