Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0693 | 0.075 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.0693 | 0.0693 |
Loa Loa (eye worm) | RNA binding protein | 0.0133 | 0.4531 | 0.4531 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0237 | 0.9241 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.4531 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0705 | 0.1556 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0693 | 0.153 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.0693 | 0.0693 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0071 | 0.172 | 0.172 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.4531 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0103 | 0.3203 | 0.3203 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0254 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0693 | 0.075 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.4531 | 1 |
Brugia malayi | TAR-binding protein | 0.0133 | 0.4531 | 0.4531 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0237 | 0.9241 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0693 | 0.075 |
Schistosoma mansoni | survival motor neuron protein | 0.0048 | 0.0705 | 0.1556 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0103 | 0.3203 | 0.3203 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0133 | 0.4531 | 0.4531 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0693 | 0.153 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.4531 | 1 |
Brugia malayi | hypothetical protein | 0.0237 | 0.9241 | 0.9241 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0133 | 0.4531 | 0.4531 |
Loa Loa (eye worm) | hypothetical protein | 0.0237 | 0.9241 | 0.9241 |
Echinococcus multilocularis | tar DNA binding protein | 0.0133 | 0.4531 | 0.4903 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.5533 | 0.5533 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0693 | 0.153 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.3203 | 0.3203 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0103 | 0.3203 | 0.3203 |
Onchocerca volvulus | 0.0155 | 0.5533 | 1 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.4531 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.172 | 0.3797 |
Brugia malayi | RNA binding protein | 0.0133 | 0.4531 | 0.4531 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.172 | 0.172 |
Echinococcus granulosus | tar DNA binding protein | 0.0133 | 0.4531 | 0.4903 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0048 | 0.0705 | 0.0705 |
Brugia malayi | hypothetical protein | 0.0155 | 0.5533 | 0.5533 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0693 | 0.075 |
Loa Loa (eye worm) | TAR-binding protein | 0.0133 | 0.4531 | 0.4531 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.