Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0787 | 0.0718 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.1398 | 0.5 |
Schistosoma mansoni | ferritin | 0.0018 | 0.0353 | 0.0353 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0648 | 0.0648 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0216 | 0.0142 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0787 | 0.5 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.1398 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0203 | 0.4967 | 0.493 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.1056 | 0.0989 |
Schistosoma mansoni | tar DNA-binding protein | 0.0203 | 0.4967 | 0.4967 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0556 | 0.0556 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0251 | 0.0274 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0556 | 0.0904 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.1056 | 0.1939 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.1398 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.1398 | 1 |
Schistosoma mansoni | lamin | 0.0026 | 0.0556 | 0.0556 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0648 | 0.0578 |
Brugia malayi | hypothetical protein | 0.013 | 0.3136 | 0.6227 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.1056 | 0.0989 |
Echinococcus granulosus | expressed protein | 0.0018 | 0.0353 | 0.0281 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0608 | 0.0608 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0787 | 0.0718 |
Schistosoma mansoni | lamin | 0.0026 | 0.0556 | 0.0556 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.1403 | 0.1403 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0556 | 0.0485 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0118 | 0.0044 |
Schistosoma mansoni | ferritin light chain | 0.0018 | 0.0353 | 0.0353 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0203 | 0.4967 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.1398 | 1 |
Trichomonas vaginalis | ferritin, putative | 0.0018 | 0.0353 | 1 |
Brugia malayi | TAR-binding protein | 0.0203 | 0.4967 | 1 |
Schistosoma mansoni | ferritin | 0.0018 | 0.0353 | 0.0353 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0787 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0787 | 0.5 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0556 | 0.0904 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.1056 | 0.1935 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0544 | 0.0879 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0018 | 0.0353 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.3136 | 0.6224 |
Brugia malayi | RNA binding protein | 0.0203 | 0.4967 | 1 |
Echinococcus multilocularis | ferritin | 0.0018 | 0.0353 | 0.0281 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.1398 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0203 | 0.4967 | 0.493 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.1056 | 0.0989 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0608 | 0.101 |
Schistosoma mansoni | hypothetical protein | 0.0405 | 1 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0118 | 0.0044 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0648 | 0.0578 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0787 | 0.5 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0556 | 0.0485 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0556 | 0.0485 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0018 | 0.0353 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0203 | 0.4967 | 1 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0648 | 0.0648 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0787 | 0.0787 |
Schistosoma mansoni | apoferritin-2 | 0.0018 | 0.0353 | 0.0353 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0216 | 0.0202 |
Schistosoma mansoni | apoferritin-2 | 0.0018 | 0.0353 | 0.0353 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0204 | 0.0177 |
Echinococcus granulosus | lamin | 0.0026 | 0.0556 | 0.0485 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.1398 | 0.1398 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.1398 | 0.1333 |
Echinococcus multilocularis | expressed protein | 0.0018 | 0.0353 | 0.0281 |
Schistosoma mansoni | ferritin | 0.0018 | 0.0353 | 0.0353 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0405 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.1056 | 0.1056 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0787 | 0.1385 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.1398 | 0.1333 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.1056 | 0.0989 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0556 | 0.0909 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.1398 | 0.1398 |
Onchocerca volvulus | Huntingtin homolog | 0.013 | 0.3136 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0556 | 0.0485 |
Onchocerca volvulus | Huntingtin homolog | 0.013 | 0.3136 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0556 | 0.0904 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0556 | 0.0909 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0018 | 0.0353 | 0.5 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0074 | 0.0074 |
Schistosoma mansoni | ferritin | 0.0018 | 0.0353 | 0.0353 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0787 | 0.0787 |
Loa Loa (eye worm) | RNA binding protein | 0.0203 | 0.4967 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0556 | 0.0485 |
Onchocerca volvulus | 0.0028 | 0.0608 | 0.02 | |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.0251 | 0.028 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.1056 | 0.1056 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0216 | 0.0142 |
Schistosoma mansoni | ferritin light chain | 0.0018 | 0.0353 | 0.0353 |
Schistosoma mansoni | tar DNA-binding protein | 0.0203 | 0.4967 | 0.4967 |
Schistosoma mansoni | tar DNA-binding protein | 0.0203 | 0.4967 | 0.4967 |
Schistosoma mansoni | tar DNA-binding protein | 0.0203 | 0.4967 | 0.4967 |
Loa Loa (eye worm) | TAR-binding protein | 0.0203 | 0.4967 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0203 | 0.4967 | 0.4967 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0608 | 0.1015 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0204 | 0.0177 |
Echinococcus granulosus | ferritin | 0.0018 | 0.0353 | 0.0281 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.3136 | 0.6224 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.1056 | 0.1056 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.