Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | AMP-binding enzyme family protein | 0.0046 | 0.0422 | 0.0767 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0068 | 0.0081 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0014 | 0.0008 | 0.001 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.003 | 0.0214 | 0.0389 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0089 | 0.0977 | 0.0977 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0021 | 0.0098 | 0.2319 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.003 | 0.0214 | 0.0252 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0021 | 0.0098 | 0.2319 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0024 | 0.0044 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0014 | 0.0008 | 0.001 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0021 | 0.0098 | 0.2319 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.1951 | 0.23 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0065 | 0.2939 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.003 | 0.0214 | 0.0214 |
Schistosoma mansoni | nuclear receptor | 0.0014 | 0.0008 | 0.001 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.0068 | 0.1623 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0023 | 0.059 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0046 | 0.0422 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0046 | 0.0422 | 0.0767 |
Schistosoma mansoni | nuclear receptor | 0.0014 | 0.0008 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0271 | 0.0493 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0021 | 0.0098 | 0.2319 |
Onchocerca volvulus | Huntingtin homolog | 0.0119 | 0.1362 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0021 | 0.0098 | 0.2319 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0021 | 0.0098 | 0.2319 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.0068 | 1 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0021 | 0.0098 | 0.2507 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0015 | 0.0023 | 0.0042 |
Schistosoma mansoni | lamin | 0.0026 | 0.0165 | 0.0195 |
Schistosoma mansoni | thyroid hormone receptor | 0.0281 | 0.3451 | 0.4068 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0008 | 0.0015 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0046 | 0.0422 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0014 | 0.0008 | 0.001 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.003 | 0.0214 | 0.0252 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.003 | 0.0214 | 0.0389 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.003 | 0.0214 | 0.0389 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0165 | 0.0195 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0039 | 0.0323 | 0.0588 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0023 | 0.0027 |
Brugia malayi | Cytochrome P450 family protein | 0.0021 | 0.0098 | 0.0178 |
Brugia malayi | hypothetical protein | 0.0119 | 0.1362 | 0.2478 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.003 | 0.0214 | 0.0252 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0016 | 0.003 | 0.0036 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0065 | 0.1548 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0065 | 0.9535 |
Brugia malayi | nuclear receptor RXR | 0.0014 | 0.0008 | 0.0015 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0246 | 0.5844 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0454 | 0.0827 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0065 | 0.0077 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0023 | 0.0023 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0016 | 0.003 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0024 | 0.0044 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0165 | 0.0165 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0021 | 0.0098 | 0.2319 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.0068 | 0.1754 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0021 | 0.0098 | 0.2319 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0165 | 0.0301 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0046 | 0.0422 | 1 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0014 | 0.0008 | 0.0008 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0246 | 0.5844 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0035 | 0.0271 | 1 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0007 | 0.0013 |
Brugia malayi | nuclear receptor NHR-88 | 0.0014 | 0.0008 | 0.0015 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0246 | 0.5844 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0021 | 0.0098 | 0.2319 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0214 | 0.0389 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0014 | 0.0008 | 0.001 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.003 | 0.0214 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0271 | 0.0493 |
Brugia malayi | conserved hypotetical protein | 0.0014 | 0.0008 | 0.0015 |
Brugia malayi | cytochrome P450 | 0.0021 | 0.0098 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.003 | 0.0055 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.003 | 0.0214 | 0.0252 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0098 | 0.0115 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0008 | 0.0015 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0046 | 0.0422 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.003 | 0.0214 | 0.0389 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0046 | 0.0422 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0672 | 0.8484 | 0.8484 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0165 | 0.0301 |
Schistosoma mansoni | DNA polymerase eta | 0.0044 | 0.039 | 0.046 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.003 | 0.0214 | 0.0252 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.0977 | 0.1152 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.003 | 0.0214 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0214 | 0.0389 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0454 | 0.0827 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0021 | 0.0098 | 0.0115 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0097 | 0.1079 | 0.1964 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0068 | 0.1754 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0035 | 0.0271 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.003 | 0.0214 | 0.0214 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0021 | 0.0098 | 0.2319 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.0068 | 0.0081 |
Brugia malayi | nuclear receptor RXR | 0.0016 | 0.003 | 0.0055 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0035 | 0.0271 | 0.6421 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0065 | 0.0077 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0021 | 0.0098 | 0.2319 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0021 | 0.0098 | 0.2319 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0014 | 0.0008 | 0.001 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0046 | 0.0422 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0068 | 0.0125 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0165 | 0.0195 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0065 | 0.9535 |
Schistosoma mansoni | nuclear hormone receptor | 0.003 | 0.0214 | 0.0252 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0165 | 0.0301 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0021 | 0.0098 | 0.2319 |
Brugia malayi | ecdysone receptor | 0.0014 | 0.0008 | 0.0015 |
Echinococcus multilocularis | 0.0021 | 0.0098 | 0.0098 | |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.003 | 0.0214 | 0.0214 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.003 | 0.0214 | 0.0389 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0024 | 0.0028 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.003 | 0.0214 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0271 | 0.0493 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.003 | 0.0214 | 0.0214 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0021 | 0.0098 | 0.2319 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.003 | 0.0214 | 0.0389 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0021 | 0.0098 | 0.2319 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0065 | 0.1673 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0422 | 0.0767 |
Onchocerca volvulus | 0.0014 | 0.0008 | 0.0061 | |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.003 | 0.0214 | 0.0389 |
Onchocerca volvulus | 0.0026 | 0.0165 | 0.1213 | |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0165 | 0.0301 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0046 | 0.0422 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0044 | 0.039 | 0.9252 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0251 | 0.3062 | 0.361 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0159 | 0.0289 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0046 | 0.0422 | 1 |
Brugia malayi | ecdysteroid receptor | 0.003 | 0.0214 | 0.0389 |
Brugia malayi | Isocitrate dehydrogenase | 0.0015 | 0.0023 | 0.0042 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0021 | 0.0098 | 0.2319 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.003 | 0.0214 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.1362 | 0.2478 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0014 | 0.0008 | 0.0008 |
Echinococcus granulosus | FTZ F1 alpha | 0.003 | 0.0214 | 0.0252 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0021 | 0.0098 | 0.2319 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0021 | 0.0098 | 0.2319 |
Schistosoma mansoni | coup transcription factor | 0.003 | 0.0214 | 0.0252 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.003 | 0.0214 | 0.157 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0014 | 0.0008 | 0.0015 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.003 | 0.0214 | 0.0252 |
Brugia malayi | Cytochrome P450 family protein | 0.0097 | 0.1079 | 0.1964 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0046 | 0.0422 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0014 | 0.0008 | 0.0008 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0014 | 0.0008 | 0.0015 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0065 | 0.1548 |
Onchocerca volvulus | 0.0014 | 0.0008 | 0.0061 | |
Mycobacterium ulcerans | hypothetical protein | 0.0046 | 0.0422 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0068 | 0.1754 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0068 | 0.1754 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0089 | 0.0977 | 0.1779 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.0068 | 0.1623 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0422 | 0.0767 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.003 | 0.0214 | 0.0389 |
Brugia malayi | hypothetical protein | 0.0016 | 0.003 | 0.0055 |
Leishmania major | cytochrome p450-like protein | 0.0021 | 0.0098 | 0.2319 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0015 | 0.0023 | 0.059 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.003 | 0.0214 | 0.0389 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0024 | 0.0024 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0021 | 0.0098 | 0.2319 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0021 | 0.0098 | 0.2319 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0068 | 0.0081 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0165 | 0.0165 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0014 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0008 | 0.0015 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0021 | 0.0098 | 0.2319 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0014 | 0.0008 | 0.0008 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.1951 | 0.23 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0068 | 0.1754 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0024 | 0.0044 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0046 | 0.0422 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.003 | 0.0214 | 0.157 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0068 | 0.1754 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.003 | 0.0214 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0214 | 0.0389 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.0068 | 0.1623 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0021 | 0.0098 | 0.2507 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0008 | 0.0015 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0014 | 0.0008 | 0.001 |
Onchocerca volvulus | 0.003 | 0.0214 | 0.157 | |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.003 | 0.0214 | 0.0252 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0068 | 0.1754 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0015 | 0.0023 | 0.1036 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0023 | 0.0546 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.003 | 0.0214 | 0.0389 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.003 | 0.0214 | 0.0389 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.0068 | 0.1623 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0014 | 0.0008 | 0.0015 |
Echinococcus multilocularis | dna polymerase eta | 0.0044 | 0.039 | 0.039 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0021 | 0.0098 | 0.2319 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0065 | 0.0065 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0046 | 0.0422 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0016 | 0.003 | 0.0055 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0021 | 0.0098 | 0.2319 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0021 | 0.0098 | 0.2319 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0065 | 0.5 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0015 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0271 | 0.0493 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0008 | 0.0015 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0065 | 0.241 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0021 | 0.0098 | 0.2319 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.003 | 0.0214 | 0.0214 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0031 | 0.0222 | 0.5692 |
Brugia malayi | hypothetical protein | 0.0014 | 0.0008 | 0.0015 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.045 | 0.5627 | 0.5627 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0014 | 0.0008 | 0.0015 |
Echinococcus granulosus | neuropeptide s receptor | 0.045 | 0.5627 | 0.6633 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0015 | 0.0023 | 0.059 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0021 | 0.0098 | 0.2319 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.003 | 0.0055 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.0068 | 1 |
Onchocerca volvulus | 0.0026 | 0.0165 | 0.1213 | |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.005 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0214 | 0.0389 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0016 | 0.003 | 0.0055 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0117 | 0.1332 | 0.2424 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.003 | 0.0214 | 0.0389 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0014 | 0.0008 | 0.001 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.003 | 0.0214 | 0.0252 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0015 | 0.0023 | 0.0023 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0089 | 0.0977 | 0.1152 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0024 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.003 | 0.0055 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0023 | 0.059 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0024 | 0.0044 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.003 | 0.0214 | 0.0252 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0068 | 0.1623 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0008 | 0.0015 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0016 | 0.003 | 0.003 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.003 | 0.0214 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0214 | 0.0389 |
Brugia malayi | hypothetical protein | 0.0014 | 0.0008 | 0.0015 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0044 | 0.039 | 0.071 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.003 | 0.0055 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.003 | 0.0214 | 0.0389 |
Loa Loa (eye worm) | DR-78 | 0.0014 | 0.0008 | 0.0015 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0068 | 0.1754 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.039 | 0.071 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0014 | 0.0008 | 0.0015 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0255 | 0.0301 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0065 | 0.1673 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0454 | 0.0827 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0024 | 0.0028 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0065 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0039 | 0.0323 | 0.7663 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0046 | 0.0422 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0014 | 0.0008 | 0.001 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0255 | 0.0464 |
Brugia malayi | tailless protein | 0.0014 | 0.0008 | 0.0015 |
Echinococcus granulosus | lamin | 0.0026 | 0.0165 | 0.0195 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.003 | 0.0214 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.003 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0454 | 0.0827 |
Loa Loa (eye worm) | cytochrome P450 | 0.0021 | 0.0098 | 0.0178 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.003 | 0.0214 | 0.0252 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0672 | 0.8484 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0165 | 0.0195 |
Loa Loa (eye worm) | steroid hormone receptor | 0.003 | 0.0214 | 0.0389 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0246 | 0.5844 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0008 | 0.0015 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0065 | 0.0119 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0035 | 0.0271 | 0.6421 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0068 | 0.1754 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.003 | 0.0214 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0271 | 0.0493 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0039 | 0.0323 | 0.8283 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0068 | 0.1754 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0251 | 0.3062 | 0.3062 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0024 | 0.0028 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0065 | 0.1548 |
Schistosoma mansoni | cytochrome P450 | 0.0021 | 0.0098 | 0.0115 |
Schistosoma mansoni | hypothetical protein | 0.0251 | 0.3062 | 0.361 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.003 | 0.0214 | 0.0389 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0068 | 0.1754 |
Trypanosoma brucei | cytochrome P450, putative | 0.0039 | 0.0323 | 0.8283 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0068 | 0.1754 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0024 | 0.0028 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0015 | 0.0023 | 0.1036 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0214 | 0.0389 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0065 | 0.241 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0008 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0214 | 0.0389 |
Brugia malayi | nuclear hormone receptor | 0.003 | 0.0214 | 0.0389 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0031 | 0.0222 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0023 | 0.0023 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0021 | 0.0098 | 0.2319 |
Leishmania major | cytochrome p450-like protein | 0.0039 | 0.0323 | 0.7663 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0021 | 0.0098 | 0.2319 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.003 | 0.0214 | 0.0252 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0046 | 0.0422 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0068 | 0.1754 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0021 | 0.0098 | 0.2319 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0068 | 0.1754 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0008 | 0.0015 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0068 | 0.1754 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0021 | 0.0098 | 0.2319 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.003 | 0.0214 | 0.0252 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0021 | 0.0098 | 0.2319 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0068 | 0.0081 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0089 | 0.0977 | 0.1152 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.003 | 0.0214 | 0.0252 |
Brugia malayi | Muscleblind-like protein | 0.044 | 0.5496 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0046 | 0.0422 | 0.0767 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0065 | 0.1548 |
Brugia malayi | nuclear receptor NHR-88 | 0.003 | 0.0214 | 0.0389 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.003 | 0.0214 | 0.0389 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.0977 | 0.1152 |
Brugia malayi | steroid hormone receptor | 0.003 | 0.0214 | 0.0389 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0044 | 0.039 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.044 | 0.5496 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0021 | 0.0098 | 0.2319 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0021 | 0.0098 | 0.2507 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0021 | 0.0098 | 0.2319 |
Brugia malayi | isocitrate dehydrogenase | 0.0015 | 0.0023 | 0.0042 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.0068 | 0.0125 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0014 | 0.0008 | 0.0015 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0021 | 0.0098 | 0.2319 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.0068 | 0.1623 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0016 | 0.003 | 0.0055 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.003 | 0.0214 | 0.0252 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0117 | 0.1332 | 0.2424 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0039 | 0.0323 | 0.8283 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0046 | 0.0422 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0046 | 0.0422 | 1 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0021 | 0.0098 | 0.2319 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.0068 | 0.0068 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.0068 | 1 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0021 | 0.0098 | 0.2507 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0046 | 0.0422 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0016 | 0.003 | 0.0036 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0089 | 0.0977 | 0.0977 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0023 | 0.0023 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0021 | 0.0098 | 0.2319 |
Schistosoma mansoni | thyroid hormone receptor | 0.0281 | 0.3451 | 0.4068 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.003 | 0.0214 | 0.0252 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0046 | 0.0422 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0281 | 0.3451 | 0.3451 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0065 | 0.1673 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0065 | 0.0077 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0008 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.044 | 0.5496 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0008 | 0.0015 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0672 | 0.8484 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0039 | 0.0323 | 0.0588 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.1362 | 0.2478 |
Echinococcus multilocularis | muscleblind protein 1 | 0.044 | 0.5496 | 0.5496 |
Brugia malayi | Cytochrome P450 family protein | 0.0039 | 0.0323 | 0.0588 |
Leishmania major | cytochrome p450-like protein | 0.0021 | 0.0098 | 0.2319 |
Echinococcus multilocularis | neuropeptide s receptor | 0.045 | 0.5627 | 0.5627 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0014 | 0.0008 | 0.0061 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0015 | 0.0023 | 0.0027 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0089 | 0.0977 | 0.1779 |
Echinococcus multilocularis | FTZ F1 alpha | 0.003 | 0.0214 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0422 | 0.0767 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0015 | 0.0023 | 0.085 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0021 | 0.0098 | 0.4404 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0024 | 0.0024 |
Onchocerca volvulus | 0.0046 | 0.0422 | 0.3095 | |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0008 | 0.0015 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0021 | 0.0098 | 0.2319 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.003 | 0.0214 | 0.0389 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.003 | 0.0214 | 0.0389 |
Onchocerca volvulus | Huntingtin homolog | 0.0119 | 0.1362 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0014 | 0.0008 | 0.0008 |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.1332 | 0.2424 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0039 | 0.0323 | 0.0588 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0021 | 0.0098 | 0.2319 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0014 | 0.0008 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0008 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0214 | 0.0389 |
Leishmania major | DNA polymerase eta, putative | 0.0031 | 0.0222 | 0.5266 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0068 | 0.1754 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0024 | 0.0028 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.0007 | 0.0013 |
Mycobacterium leprae | putative cytochrome p450 | 0.0021 | 0.0098 | 0.2319 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0014 | 0.0008 | 0.0015 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0021 | 0.0098 | 0.2319 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0024 | 0.0028 |
Brugia malayi | hypothetical protein | 0.0016 | 0.003 | 0.0055 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0014 | 0.0008 | 0.0061 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0068 | 0.1623 |
Echinococcus multilocularis | geminin | 0.0165 | 0.1951 | 0.1951 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.0977 | 0.1152 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0035 | 0.0271 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0068 | 0.1754 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0039 | 0.0323 | 0.0588 |
Schistosoma mansoni | nuclear hormone receptor | 0.0014 | 0.0008 | 0.001 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0068 | 0.0068 |
Echinococcus granulosus | dna polymerase eta | 0.0044 | 0.039 | 0.046 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0014 | 0.0008 | 0.001 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0014 | 0.0008 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0255 | 0.0464 |
Brugia malayi | nuclear hormone receptor | 0.0014 | 0.0008 | 0.0015 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0165 | 0.0165 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0065 | 0.0119 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0068 | 0.1754 |
Onchocerca volvulus | Bile acid receptor homolog | 0.003 | 0.0214 | 0.157 |
Echinococcus granulosus | muscleblind protein | 0.044 | 0.5496 | 0.6478 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.003 | 0.0214 | 0.0252 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0044 | 0.039 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0021 | 0.0098 | 0.2319 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0014 | 0.0008 | 0.001 |
Brugia malayi | nuclear receptor NHR-67 | 0.0014 | 0.0008 | 0.0015 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0165 | 0.0301 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.003 | 0.0214 | 0.0389 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0015 | 0.0023 | 0.085 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0014 | 0.0008 | 0.001 |
Echinococcus granulosus | geminin | 0.0165 | 0.1951 | 0.23 |
Echinococcus multilocularis | muscleblind protein | 0.044 | 0.5496 | 0.5496 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0015 | 0.0023 | 0.0546 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0021 | 0.0098 | 0.2319 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.045 | 0.5627 | 0.6633 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0024 | 0.0028 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0021 | 0.0098 | 0.2319 |
Schistosoma mansoni | lamin | 0.0026 | 0.0165 | 0.0195 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.