Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | flap endonuclease 1 | 0.0026 | 0.0127 | 0.0223 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0061 | 0.0409 | 0.1076 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0117 | 0.0848 | 0.223 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0011 | 0.001 | 0.001 |
Brugia malayi | tailless protein | 0.0029 | 0.0153 | 0.0395 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0029 | 0.0153 | 0.0271 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.044 | 0.3395 | 0.5531 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0061 | 0.0409 | 0.1069 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0026 | 0.0127 | 0.0333 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0181 | 0.0475 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0047 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0409 | 0.1076 |
Echinococcus granulosus | axis inhibition protein axin | 0.0011 | 0.001 | 0.0011 |
Plasmodium vivax | hypothetical protein, conserved | 0.0117 | 0.0848 | 1 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0011 | 0.001 | 0.001 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0061 | 0.0409 | 0.0737 |
Giardia lamblia | GTOR | 0.0047 | 0.0295 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0165 | 0.1923 |
Echinococcus granulosus | cpg binding protein | 0.0034 | 0.0196 | 0.0349 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0029 | 0.0153 | 0.0271 |
Plasmodium falciparum | flap endonuclease 1 | 0.0026 | 0.0127 | 0.5 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.002 | 0.0078 | 0.003 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0047 | 0.0078 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0047 | 0.0295 | 0.0769 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0061 | 0.0409 | 0.0661 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0127 | 0.0334 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.001 | 0.009 |
Brugia malayi | hypothetical protein | 0.0455 | 0.3514 | 0.9239 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0026 | 0.0127 | 0.0078 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0011 | 0.001 | 0.0019 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0032 | 0.0181 | 0.0468 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0047 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0181 | 0.0475 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.018 | 0.1341 | 0.1299 |
Schistosoma mansoni | nuclear hormone receptor | 0.0061 | 0.0409 | 0.0757 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0029 | 0.0153 | 0.0243 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0311 | 0.0812 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0029 | 0.0153 | 0.0243 |
Brugia malayi | hypothetical protein | 0.0011 | 0.001 | 0.0019 |
Mycobacterium leprae | conserved hypothetical protein | 0.0117 | 0.0848 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0061 | 0.0409 | 0.0737 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0061 | 0.0409 | 0.1069 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0061 | 0.0409 | 0.1069 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0219 | 0.2564 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0061 | 0.0409 | 0.0737 |
Mycobacterium leprae | Probable lipase LipE | 0.0117 | 0.0848 | 0.5 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0011 | 0.001 | 0.001 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0219 | 0.2564 |
Loa Loa (eye worm) | RGS-3 protein | 0.0011 | 0.001 | 0.0027 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0605 | 0.4693 | 0.4667 |
Brugia malayi | nuclear receptor NHR-67 | 0.0029 | 0.0153 | 0.0395 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0153 | 0.0403 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0189 | 0.049 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0013 | 0.0024 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0153 | 0.0403 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.02 | 0.2338 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0409 | 0.1076 |
Schistosoma mansoni | thyroid hormone receptor | 0.044 | 0.3395 | 0.642 |
Onchocerca volvulus | 0.0117 | 0.0848 | 0.2119 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.001 | 0.009 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0117 | 0.0848 | 0.1589 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0049 | 0.0547 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0131 | 0.0344 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.001 | 0.009 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0117 | 0.0848 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0153 | 0.0403 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.02 | 0.2338 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0061 | 0.0409 | 0.0757 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0131 | 0.0207 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0124 | 0.144 |
Echinococcus granulosus | lamin | 0.0026 | 0.0131 | 0.0231 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0181 | 0.0475 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0026 | 0.0127 | 0.0078 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.018 | 0.1341 | 0.1299 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0409 | 0.1076 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0061 | 0.0409 | 0.1076 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0016 | 0.0049 | 0.0128 |
Brugia malayi | regulator of G-protein signaling rgs-7 | 0.0011 | 0.001 | 0.0019 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0032 | 0.0181 | 0.0468 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0409 | 0.1076 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0311 | 0.0819 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0189 | 0.0497 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0295 | 0.3462 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0037 | 0.022 | 0.0172 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0144 | 0.1671 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0219 | 0.2564 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0125 | 0.1444 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0029 | 0.0153 | 0.0243 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0061 | 0.0409 | 0.0737 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0061 | 0.0409 | 0.0661 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0004 | 0.001 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0032 | 0.0181 | 0.0475 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0295 | 0.3462 |
Echinococcus multilocularis | expressed protein | 0.0011 | 0.001 | 0.001 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0061 | 0.0409 | 0.0737 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0032 | 0.0173 | 0.2018 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0061 | 0.0409 | 0.0823 |
Echinococcus granulosus | Regulator of G protein signaling 20 | 0.0011 | 0.001 | 0.0011 |
Brugia malayi | nuclear hormone receptor | 0.0061 | 0.0409 | 0.1069 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0848 | 0.223 |
Loa Loa (eye worm) | DR-78 | 0.0029 | 0.0153 | 0.0403 |
Onchocerca volvulus | 0.0117 | 0.0848 | 0.2119 | |
Onchocerca volvulus | 0.0061 | 0.0409 | 0.0823 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0219 | 0.2564 |
Onchocerca volvulus | 0.0104 | 0.0741 | 0.1803 | |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0061 | 0.0409 | 0.0823 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.1277 | 1 | 1 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.0105 | 0.0753 | 0.198 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0047 | 0.0295 | 0.0248 |
Brugia malayi | beta-lactamase family protein | 0.0117 | 0.0848 | 0.2224 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0011 | 0.0012 | 0.0004 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.018 | 0.1341 | 0.1299 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0848 | 0.223 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0061 | 0.0409 | 0.0757 |
Echinococcus granulosus | axis inhibition protein axin | 0.0011 | 0.001 | 0.0011 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0061 | 0.0409 | 0.1069 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0061 | 0.0409 | 0.1076 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0032 | 0.0181 | 0.0288 |
Brugia malayi | ecdysteroid receptor | 0.0061 | 0.0409 | 0.1069 |
Onchocerca volvulus | 0.0029 | 0.0153 | 0.0066 | |
Schistosoma mansoni | lamin | 0.0026 | 0.0131 | 0.0229 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0052 | 0.0335 | 0.0881 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0117 | 0.0848 | 0.0803 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0117 | 0.0848 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0029 | 0.0153 | 0.0395 |
Brugia malayi | ecdysone receptor | 0.0029 | 0.0153 | 0.0395 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.0011 | 0.0012 | 0.0025 |
Toxoplasma gondii | ABC1 family protein | 0.0117 | 0.0848 | 0.5465 |
Schistosoma mansoni | nuclear hormone receptor | 0.0029 | 0.0153 | 0.0271 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0029 | 0.0153 | 0.0271 |
Echinococcus granulosus | A kinase anchor protein 10 mitochondrial | 0.0011 | 0.001 | 0.0011 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0311 | 0.0812 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0037 | 0.022 | 0.0172 |
Brugia malayi | PXA domain containing protein | 0.0011 | 0.001 | 0.0019 |
Leishmania major | hypothetical protein, conserved | 0.0117 | 0.0848 | 0.0803 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0029 | 0.0153 | 0.0395 |
Brugia malayi | nuclear receptor RXR | 0.0032 | 0.0181 | 0.0468 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0335 | 0.054 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0181 | 0.0468 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0061 | 0.0409 | 0.1069 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0061 | 0.0409 | 0.1069 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0409 | 0.1076 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0379 | 0.291 | 0.5286 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.0007 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0029 | 0.0153 | 0.0066 |
Schistosoma mansoni | lozenge | 0.0057 | 0.0375 | 0.0691 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0047 | 0.0295 | 0.0776 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0047 | 0.0078 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.0105 | 0.0753 | 0.1222 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0047 | 0.0295 | 1 |
Schistosoma mansoni | survival motor neuron protein | 0.01 | 0.0716 | 0.1338 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0117 | 0.0848 | 0.1589 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0047 | 0.0295 | 0.0248 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0492 | 0.3803 | 0.6197 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0153 | 0.0403 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0181 | 0.0325 |
Brugia malayi | beta-lactamase | 0.0117 | 0.0848 | 0.2224 |
Schistosoma mansoni | lamin | 0.0026 | 0.0131 | 0.0229 |
Schistosoma mansoni | nuclear receptor | 0.0029 | 0.0153 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0153 | 0.0403 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0131 | 0.0344 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0105 | 0.0753 | 0.1409 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0335 | 0.054 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0047 | 0.0295 | 0.0248 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0016 | 0.0049 | 0.0121 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0016 | 0.0049 | 0.0082 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0181 | 0.0468 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.0035 | 0.0085 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0787 | 0.6135 | 1 |
Echinococcus multilocularis | tumor protein p63 | 0.0707 | 0.5502 | 0.8968 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0061 | 0.0409 | 0.0823 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0061 | 0.0409 | 0.0757 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0027 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0035 | 0.02 | 0.1278 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0409 | 0.1076 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0029 | 0.0153 | 0.0271 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0029 | 0.0153 | 0.0271 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0047 | 0.0123 |
Brugia malayi | A-kinase anchor protein 10, precursor | 0.0011 | 0.001 | 0.0019 |
Brugia malayi | PXA domain containing protein | 0.0011 | 0.001 | 0.0019 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0196 | 0.0352 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0241 | 0.282 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0032 | 0.0181 | 0.0323 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0131 | 0.0344 |
Echinococcus multilocularis | cpg binding protein | 0.0034 | 0.0196 | 0.0313 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0022 | 0.01 | 0.0051 |
Schistosoma mansoni | flap endonuclease-1 | 0.0023 | 0.0107 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0311 | 0.0819 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.02 | 0.2338 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0061 | 0.0409 | 0.1069 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0029 | 0.0153 | 0.0395 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0061 | 0.0409 | 0.0661 |
Echinococcus granulosus | expressed protein | 0.0011 | 0.001 | 0.0011 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.02 | 0.2338 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.002 | 0.0053 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0029 | 0.0153 | 0.0243 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0153 | 0.0395 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0061 | 0.0409 | 0.0661 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0061 | 0.0409 | 0.0661 |
Loa Loa (eye worm) | beta-lactamase | 0.0117 | 0.0848 | 0.223 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0061 | 0.0409 | 0.0737 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0049 | 0.0547 |
Onchocerca volvulus | 0.0455 | 0.3514 | 1 | |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0029 | 0.0153 | 0.0271 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0029 | 0.0153 | 0.0271 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0117 | 0.0848 | 0.2224 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0061 | 0.0409 | 0.0757 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0011 | 0.001 | 0.0011 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0131 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0741 | 0.1948 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0026 | 0.0127 | 0.02 |
Onchocerca volvulus | 0.01 | 0.0716 | 0.1728 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.001 | 0.009 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0047 | 0.0295 | 0.0248 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.002 | 0.0053 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0047 | 0.0295 | 0.0541 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.1277 | 1 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0117 | 0.0848 | 1 |
Onchocerca volvulus | 0.0033 | 0.0181 | 0.0149 | |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0061 | 0.0409 | 0.1069 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0047 | 0.0295 | 0.0248 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0125 | 0.1444 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0047 | 0.0295 | 0.0475 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.001 | 0.009 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0061 | 0.0409 | 0.1076 |
Trichomonas vaginalis | regulator of G protein signaling 5, rgs5, putative | 0.0011 | 0.001 | 0.009 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0069 | 0.0469 | 0.0871 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0848 | 0.223 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0024 | 0.0037 |
Brugia malayi | nuclear receptor RXR | 0.0029 | 0.0153 | 0.0395 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0047 | 0.0078 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0335 | 0.0616 |
Echinococcus multilocularis | regulator of G protein signaling | 0.0011 | 0.001 | 0.001 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0061 | 0.0409 | 0.1069 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0061 | 0.0409 | 0.1069 |
Toxoplasma gondii | hypothetical protein | 0.0206 | 0.155 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0125 | 0.1444 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0037 | 0.022 | 0.0172 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0131 | 0.0337 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0144 | 0.1671 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0131 | 0.0207 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0052 | 0.0335 | 0.0874 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0061 | 0.0409 | 0.1069 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0131 | 0.0229 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0029 | 0.0153 | 0.0403 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0061 | 0.0409 | 0.0737 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0024 | 0.0063 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0035 | 0.0092 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.018 | 0.1341 | 0.1299 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0124 | 0.144 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0049 | 0.0547 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0029 | 0.0153 | 0.0395 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0117 | 0.0848 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0032 | 0.0181 | 0.0321 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0153 | 0.0403 |
Brugia malayi | steroid hormone receptor | 0.0061 | 0.0409 | 0.1069 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0061 | 0.0409 | 0.1076 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0153 | 0.0403 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0047 | 0.007 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0029 | 0.0153 | 0.0395 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0011 | 0.001 | 0.0011 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0061 | 0.0409 | 0.1069 |
Echinococcus granulosus | FTZ F1 alpha | 0.0061 | 0.0409 | 0.0737 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0295 | 0.3462 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0061 | 0.0409 | 0.0661 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0016 | 0.0049 | 0.0073 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0047 | 0.0295 | 0.053 |
Brugia malayi | nuclear receptor NHR-88 | 0.0029 | 0.0153 | 0.0395 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0848 | 0.223 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0061 | 0.0409 | 0.1069 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0679 | 0.5282 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0848 | 0.223 |
Brugia malayi | Flap endonuclease-1 | 0.0026 | 0.0127 | 0.0326 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0061 | 0.0409 | 0.0661 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.02 | 0.2338 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0146 | 0.1697 |
Brugia malayi | CXXC zinc finger family protein | 0.0033 | 0.0181 | 0.0469 |
Brugia malayi | conserved hypotetical protein | 0.0029 | 0.0153 | 0.0395 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0146 | 0.1697 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0029 | 0.0153 | 0.0243 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0061 | 0.0409 | 0.0757 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0409 | 0.1076 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0061 | 0.0409 | 0.0757 |
Echinococcus multilocularis | Regulator of G protein signaling 20 | 0.0011 | 0.001 | 0.001 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0131 | 0.0231 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0061 | 0.0409 | 0.1069 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0061 | 0.0409 | 0.1076 |
Loa Loa (eye worm) | runx1 | 0.0057 | 0.0375 | 0.0985 |
Schistosoma mansoni | zinc finger protein | 0.0029 | 0.0153 | 0.0271 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0024 | 0.0033 |
Echinococcus granulosus | G protein coupled receptor kinase 1 | 0.0094 | 0.0667 | 0.1206 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0335 | 0.0616 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0029 | 0.0153 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0492 | 0.3803 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0153 | 0.0403 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0047 | 0.0116 |
Brugia malayi | hypothetical protein | 0.0492 | 0.3803 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0029 | 0.0153 | 0.0271 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0061 | 0.0409 | 0.1076 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0153 | 0.0403 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0679 | 0.5282 | 0.96 |
Echinococcus multilocularis | A kinase anchor protein 10, mitochondrial | 0.0011 | 0.001 | 0.001 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.1277 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0379 | 0.291 | 0.5501 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0409 | 0.1076 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0131 | 0.0231 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0673 | 0.5232 | 0.8808 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0011 | 0.001 | 0.0011 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0605 | 0.4693 | 0.4667 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0029 | 0.0153 | 0.0395 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0061 | 0.0409 | 0.1069 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0117 | 0.0848 | 0.1535 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0492 | 0.3803 | 0.691 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0047 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0181 | 0.0475 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0061 | 0.0409 | 0.1076 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0047 | 0.007 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0117 | 0.0848 | 0.0803 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0848 | 0.223 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0748 | 0.5825 | 1 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0011 | 0.001 | 0.0019 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0016 | 0.0049 | 0.0073 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0033 | 0.0181 | 0.0477 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0146 | 0.1697 |
Entamoeba histolytica | Flap nuclease, putative | 0.0026 | 0.0127 | 0.4085 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0011 | 0.001 | 0.001 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0049 | 0.0547 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.0026 | 0.0127 | 0.1467 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0029 | 0.0153 | 0.0403 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0196 | 0.0352 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0032 | 0.0181 | 0.0323 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0605 | 0.4693 | 0.4667 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0104 | 0.0741 | 0.1386 |
Onchocerca volvulus | 0.0117 | 0.0848 | 0.2119 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0335 | 0.0602 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0335 | 0.0602 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0029 | 0.0153 | 0.0243 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0117 | 0.0848 | 0.0803 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0124 | 0.144 |
Brugia malayi | beta-lactamase family protein | 0.0117 | 0.0848 | 0.2224 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.02 | 0.2338 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0029 | 0.0153 | 0.0395 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0026 | 0.0127 | 0.0802 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0131 | 0.0337 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0029 | 0.0153 | 0.0066 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0117 | 0.0848 | 0.1377 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0062 | 0.0411 | 0.2641 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0105 | 0.0753 | 0.1409 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0379 | 0.291 | 0.474 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0061 | 0.0409 | 0.0737 |
Mycobacterium ulcerans | hypothetical protein | 0.0673 | 0.5232 | 1 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0047 | 0.0295 | 1 |
Loa Loa (eye worm) | PXA domain-containing protein | 0.0011 | 0.001 | 0.0027 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0061 | 0.0409 | 0.1069 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0026 | 0.0127 | 0.0078 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0153 | 0.0395 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0027 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0061 | 0.0409 | 0.0757 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0153 | 0.0403 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.0716 | 0.1338 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0027 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.01 | 0.0716 | 0.1875 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0061 | 0.0409 | 0.0757 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0029 | 0.0153 | 0.0271 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0219 | 0.2564 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0049 | 0.0547 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.02 | 0.2338 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0153 | 0.0403 |
Echinococcus granulosus | tumor protein p63 | 0.0707 | 0.5502 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0679 | 0.5282 | 0.8609 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0047 | 0.007 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0047 | 0.007 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0047 | 0.0295 | 0.0248 |
Brugia malayi | nuclear receptor NHR-88 | 0.0061 | 0.0409 | 0.1069 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0455 | 0.3514 | 0.9239 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0011 | 0.001 | 0.0027 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0061 | 0.0409 | 0.0757 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.0105 | 0.0753 | 0.1362 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0029 | 0.0153 | 0.0403 |
Schistosoma mansoni | coup transcription factor | 0.0061 | 0.0409 | 0.0757 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0153 | 0.0403 |
Echinococcus multilocularis | Protein lozenge | 0.0057 | 0.0375 | 0.0605 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0011 | 0.001 | 0.001 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.0011 | 0.0012 | 0.0032 |
Echinococcus multilocularis | G protein coupled receptor kinase 1 | 0.0094 | 0.0667 | 0.1082 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0189 | 0.0339 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0011 | 0.001 | 0.0011 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0219 | 0.1651 | 0.161 |
Schistosoma mansoni | thyroid hormone receptor | 0.044 | 0.3395 | 0.642 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0061 | 0.0409 | 0.0661 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0335 | 0.0616 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0181 | 0.0475 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0117 | 0.0848 | 1 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0011 | 0.001 | 0.001 |
Schistosoma mansoni | nuclear receptor | 0.0029 | 0.0153 | 0.0271 |
Brugia malayi | hypothetical protein | 0.0011 | 0.001 | 0.0019 |
Trichomonas vaginalis | esterase, putative | 0.0117 | 0.0848 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0455 | 0.3514 | 0.9239 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0047 | 0.007 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0125 | 0.1444 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0153 | 0.0403 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.001 | 0.009 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0047 | 0.0123 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0011 | 0.001 | 0.0019 |
Onchocerca volvulus | 0.0029 | 0.0153 | 0.0066 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.