Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0012 | 0.0017 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0017 | 0.0026 |
Brugia malayi | Isocitrate dehydrogenase | 0.0017 | 0.0081 | 0.013 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0022 | 0.0155 | 0.0568 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0065 | 0.0724 | 0.1153 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0027 | 0.0223 | 0.0223 |
Schistosoma mansoni | hypothetical protein | 0.0155 | 0.1911 | 0.1911 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0246 | 0.6408 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0022 | 0.0155 | 0.0568 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0022 | 0.0148 | 0.0479 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0022 | 0.0155 | 0.0247 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0268 | 0.3396 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0017 | 0.0026 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.007 | 0.0788 | 0.0788 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0017 | 0.0081 | 0.0207 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0022 | 0.0155 | 0.0247 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0013 | 0.0034 | 0.0034 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0022 | 0.0155 | 0.0247 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0191 | 0.2379 | 0.3788 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0211 | 0.264 | 0.4204 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0035 | 0.0324 | 0.0944 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0141 | 0.1725 | 0.2747 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0155 | 0.0247 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0724 | 0.0724 |
Giardia lamblia | Pyruvate kinase | 0.0036 | 0.0339 | 0.0706 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0268 | 0.3396 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0211 | 0.264 | 0.264 |
Echinococcus granulosus | pyruvate kinase | 0.0036 | 0.0339 | 0.0339 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0743 | 0.9668 | 0.9668 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0022 | 0.0155 | 0.0155 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0036 | 0.0339 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.0324 | 0.1639 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0724 | 0.1153 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0268 | 0.3396 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0268 | 0.3396 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0081 | 0.0081 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0268 | 0.3396 | 1 |
Brugia malayi | isocitrate dehydrogenase | 0.0017 | 0.0081 | 0.013 |
Schistosoma mansoni | nuclear hormone receptor | 0.0022 | 0.0155 | 0.0155 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0486 | 0.6279 | 0.6279 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.1171 | 0.1171 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0324 | 0.0944 |
Brugia malayi | Pre-SET motif family protein | 0.0191 | 0.2379 | 0.3788 |
Schistosoma mansoni | pyruvate kinase | 0.0036 | 0.0339 | 0.0339 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0022 | 0.0155 | 0.0155 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0148 | 0.0236 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0036 | 0.0339 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0246 | 0.6482 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0022 | 0.0155 | 0.0155 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0065 | 0.0724 | 0.0724 |
Brugia malayi | TAR-binding protein | 0.0211 | 0.264 | 0.4204 |
Schistosoma mansoni | tar DNA-binding protein | 0.0211 | 0.264 | 0.264 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0029 | 0.0246 | 0.2333 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0324 | 0.0516 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0148 | 0.0236 |
Onchocerca volvulus | 0.0217 | 0.2726 | 1 | |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0207 | 0.2587 | 0.412 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0022 | 0.0155 | 0.0155 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0022 | 0.0155 | 0.0155 |
Loa Loa (eye worm) | pyruvate kinase | 0.0036 | 0.0339 | 0.054 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0022 | 0.0155 | 0.0155 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0065 | 0.0724 | 0.0724 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0268 | 0.3396 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.0324 | 0.1218 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0016 | 0.0076 | 0.0043 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0148 | 0.0236 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0155 | 0.0247 |
Echinococcus multilocularis | pyruvate kinase | 0.0036 | 0.0339 | 0.0339 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0022 | 0.0155 | 0.0155 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.0036 | 0.0339 | 0.0998 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0486 | 0.6279 | 0.6279 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0155 | 0.0247 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0268 | 0.3396 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0022 | 0.0155 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0148 | 0.0236 |
Echinococcus granulosus | GPCR family 2 | 0.0065 | 0.0724 | 0.0724 |
Echinococcus granulosus | FTZ F1 alpha | 0.0022 | 0.0155 | 0.0155 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0036 | 0.0339 | 0.054 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0224 | 0.2814 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0022 | 0.0155 | 0.0247 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0035 | 0.0324 | 0.0944 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.0324 | 0.1639 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.0246 | 0.6408 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0017 | 0.0026 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0017 | 0.0081 | 0.0081 |
Brugia malayi | Pyruvate kinase, alpha/beta domain containing protein | 0.0011 | 0.0006 | 0.001 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0324 | 0.343 |
Loa Loa (eye worm) | TAR-binding protein | 0.0211 | 0.264 | 0.4204 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0012 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0022 | 0.0155 | 0.0247 |
Schistosoma mansoni | thyroid hormone receptor | 0.0022 | 0.0155 | 0.0155 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0246 | 0.0392 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0012 | 0.0017 | 0.0017 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0324 | 0.0944 |
Schistosoma mansoni | tar DNA-binding protein | 0.0211 | 0.264 | 0.264 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0324 | 0.0516 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0036 | 0.0339 | 0.1243 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0022 | 0.0155 | 0.0155 |
Echinococcus multilocularis | geminin | 0.0155 | 0.1911 | 0.1911 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0027 | 0.0223 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0017 | 0.0026 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0724 | 0.0724 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0724 | 0.0724 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0013 | 0.0034 | 0.0034 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0027 | 0.0223 | 0.0223 |
Brugia malayi | nuclear receptor NHR-88 | 0.0022 | 0.0155 | 0.0247 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0769 | 1 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0022 | 0.0148 | 0.0479 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0324 | 0.0516 |
Echinococcus granulosus | geminin | 0.0155 | 0.1911 | 0.1911 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0022 | 0.0155 | 0.0155 |
Plasmodium vivax | pyruvate kinase, putative | 0.0036 | 0.0339 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0724 | 0.0724 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0017 | 0.0081 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0339 | 0.054 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0076 | 0.0121 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0036 | 0.0339 | 0.1243 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0036 | 0.0339 | 0.1243 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0081 | 0.0081 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0036 | 0.0339 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0324 | 0.0516 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0036 | 0.0339 | 0.3641 |
Plasmodium falciparum | pyruvate kinase 2 | 0.0019 | 0.0107 | 0.1166 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.0246 | 0.2333 |
Echinococcus granulosus | pyruvate kinase | 0.0036 | 0.0339 | 0.0339 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0022 | 0.0155 | 0.0247 |
Schistosoma mansoni | thyroid hormone receptor | 0.0022 | 0.0155 | 0.0155 |
Schistosoma mansoni | pyruvate kinase | 0.0019 | 0.0107 | 0.0107 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0268 | 0.3396 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0022 | 0.0155 | 0.0155 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0246 | 0.6482 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0268 | 0.3396 | 0.5 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0036 | 0.0339 | 0.0049 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0022 | 0.0155 | 0.0155 |
Plasmodium vivax | pyruvate kinase 2, putative | 0.0019 | 0.0107 | 0.1166 |
Schistosoma mansoni | hypothetical protein | 0.0141 | 0.1725 | 0.1725 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0324 | 0.9419 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0022 | 0.0155 | 0.0155 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0036 | 0.0339 | 0.054 |
Onchocerca volvulus | 0.0027 | 0.0223 | 0.0817 | |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0324 | 0.9419 |
Echinococcus multilocularis | pyruvate kinase | 0.0019 | 0.0107 | 0.0107 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0324 | 0.343 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0022 | 0.0155 | 0.0155 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0268 | 0.3396 | 1 |
Onchocerca volvulus | 0.0035 | 0.0324 | 0.1188 | |
Brugia malayi | Pre-SET motif family protein | 0.0027 | 0.0223 | 0.0355 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.007 | 0.0788 | 0.0788 |
Echinococcus granulosus | pyruvate kinase | 0.0019 | 0.0107 | 0.0107 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0081 | 0.0081 |
Onchocerca volvulus | 0.0022 | 0.0148 | 0.0545 | |
Toxoplasma gondii | pyruvate kinase PyKII | 0.0019 | 0.0107 | 0.0356 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.2587 | 0.412 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0012 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0155 | 0.0247 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.0324 | 0.1218 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0022 | 0.0155 | 0.0247 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0022 | 0.0155 | 0.0155 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0022 | 0.0155 | 0.0247 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0027 | 0.0223 | 0.1999 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0131 | 0.1588 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0324 | 0.0516 |
Schistosoma mansoni | pyruvate kinase | 0.0036 | 0.0339 | 0.0339 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0324 | 0.0516 |
Echinococcus multilocularis | pyruvate kinase | 0.0029 | 0.0238 | 0.0238 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0022 | 0.0155 | 0.0155 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0246 | 0.0392 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0022 | 0.0155 | 0.0247 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0027 | 0.0223 | 0.0223 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0211 | 0.264 | 0.4204 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.007 | 0.0788 | 0.2633 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0025 | 0.0194 | 0.031 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0268 | 0.3396 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0065 | 0.0724 | 0.0724 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0065 | 0.0724 | 0.0724 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0022 | 0.0148 | 0.0479 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0035 | 0.0324 | 0.0944 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.007 | 0.0788 | 0.471 |
Echinococcus multilocularis | tar DNA binding protein | 0.0211 | 0.264 | 0.264 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0022 | 0.0148 | 0.0306 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0155 | 0.0247 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0324 | 0.0516 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.0324 | 0.1639 |
Onchocerca volvulus | 0.0035 | 0.0324 | 0.1188 | |
Echinococcus multilocularis | pyruvate kinase | 0.0019 | 0.0107 | 0.0107 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0207 | 0.2587 | 0.412 |
Brugia malayi | hypothetical protein | 0.0019 | 0.011 | 0.0175 |
Schistosoma mansoni | survival motor neuron protein | 0.0099 | 0.1171 | 0.1171 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0022 | 0.0155 | 0.0155 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0012 | 0.0017 | 0.0026 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.0246 | 0.6482 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0099 | 0.1171 | 0.1864 |
Echinococcus granulosus | pyruvate kinase | 0.0019 | 0.0107 | 0.0107 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0148 | 0.0479 |
Onchocerca volvulus | 0.0022 | 0.0155 | 0.0568 | |
Plasmodium vivax | SET domain protein, putative | 0.0027 | 0.0223 | 0.5584 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0022 | 0.0155 | 0.0155 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0076 | 0.0121 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0022 | 0.0155 | 0.0247 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0022 | 0.0155 | 0.0155 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0022 | 0.0155 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0324 | 0.0516 |
Echinococcus multilocularis | pyruvate kinase | 0.0019 | 0.0107 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0324 | 0.0516 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0022 | 0.0148 | 0.0948 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0022 | 0.0155 | 0.0155 |
Trichomonas vaginalis | set domain proteins, putative | 0.0217 | 0.2726 | 0.782 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0324 | 0.0324 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0022 | 0.0155 | 0.0247 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0324 | 0.9432 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0324 | 0.0324 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.007 | 0.0788 | 0.471 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0155 | 0.0247 |
Echinococcus multilocularis | GPCR, family 2 | 0.0065 | 0.0724 | 0.0724 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0017 | 0.0081 | 0.0207 |
Brugia malayi | steroid hormone receptor | 0.0022 | 0.0155 | 0.0247 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0022 | 0.0148 | 0.0948 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0022 | 0.0155 | 0.0247 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0012 | 0.0017 | 0.0017 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.007 | 0.0788 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0027 | 0.0223 | 0.0223 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0246 | 0.6408 |
Brugia malayi | hypothetical protein | 0.0486 | 0.6279 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0486 | 0.6279 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0022 | 0.0155 | 0.0247 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0022 | 0.0155 | 0.0247 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0036 | 0.0339 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0022 | 0.0155 | 0.0155 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0036 | 0.0339 | 0.0049 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.0324 | 0.1639 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0155 | 0.0247 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0022 | 0.0155 | 0.0155 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0034 | 0.0034 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0324 | 0.9419 |
Brugia malayi | nuclear receptor RXR | 0.0012 | 0.0017 | 0.0026 |
Brugia malayi | RNA binding protein | 0.0211 | 0.264 | 0.4204 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0223 | 0.0355 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0131 | 0.1588 | 0.5542 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0148 | 0.0236 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0022 | 0.0155 | 0.0568 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0035 | 0.0324 | 0.0944 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0022 | 0.0155 | 0.0155 |
Schistosoma mansoni | tar DNA-binding protein | 0.0211 | 0.264 | 0.264 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0268 | 0.3396 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0022 | 0.0155 | 0.0247 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0148 | 0.0306 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0022 | 0.0155 | 0.0247 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0017 | 0.0081 | 0.013 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.0324 | 0.1639 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0022 | 0.0155 | 0.0247 |
Plasmodium falciparum | pyruvate kinase | 0.0036 | 0.0339 | 1 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0035 | 0.0324 | 0.0944 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0324 | 0.0944 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.007 | 0.0788 | 0.0788 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.007 | 0.0788 | 0.471 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0131 | 0.1588 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0022 | 0.0155 | 0.0155 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0148 | 0.0479 |
Schistosoma mansoni | tar DNA-binding protein | 0.0211 | 0.264 | 0.264 |
Leishmania major | pyruvate kinase | 0.0036 | 0.0339 | 0.3641 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0081 | 0.0081 |
Schistosoma mansoni | hypothetical protein | 0.0155 | 0.1911 | 0.1911 |
Loa Loa (eye worm) | pyruvate kinase | 0.0036 | 0.0339 | 0.054 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0022 | 0.0155 | 0.0155 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0017 | 0.0081 | 0.0081 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0022 | 0.0155 | 0.0247 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0035 | 0.0324 | 0.0944 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0017 | 0.0026 |
Loa Loa (eye worm) | RNA binding protein | 0.0211 | 0.264 | 0.4204 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0155 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0194 | 0.031 |
Echinococcus multilocularis | pyruvate kinase | 0.0036 | 0.0339 | 0.0339 |
Chlamydia trachomatis | pyruvate kinase | 0.0036 | 0.0339 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.007 | 0.0788 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0022 | 0.0155 | 0.0247 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0012 | 0.0017 | 0.0026 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0022 | 0.0148 | 0.0948 |
Echinococcus granulosus | pyruvate kinase | 0.0019 | 0.0107 | 0.0107 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0026 | 0.0209 | 0.0209 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0022 | 0.0155 | 0.0247 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0324 | 0.0516 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0022 | 0.0155 | 0.0155 |
Leishmania major | pyruvate kinase | 0.0036 | 0.0339 | 0.3641 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0324 | 0.0516 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0022 | 0.0155 | 0.0247 |
Loa Loa (eye worm) | pyruvate kinase | 0.0036 | 0.0339 | 0.054 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0065 | 0.0724 | 0.1153 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0148 | 0.0236 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0324 | 0.0516 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0769 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.1725 | 0.2747 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0022 | 0.0155 | 0.0155 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0035 | 0.0324 | 0.0944 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0324 | 0.0324 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0207 | 0.2587 | 0.412 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.007 | 0.0788 | 0.0788 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0065 | 0.0724 | 0.1153 |
Entamoeba histolytica | pyruvate kinase, putative | 0.0025 | 0.0194 | 0.0142 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0022 | 0.0155 | 0.0247 |
Mycobacterium ulcerans | hypothetical protein | 0.0022 | 0.0148 | 0.0479 |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.0036 | 0.0339 | 0.1322 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0017 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0076 | 0.0121 |
Onchocerca volvulus | 0.0099 | 0.1171 | 0.4294 | |
Onchocerca volvulus | 0.0035 | 0.0324 | 0.1188 | |
Mycobacterium ulcerans | pyruvate kinase | 0.0036 | 0.0339 | 0.1738 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0076 | 0.0121 |
Schistosoma mansoni | tar DNA-binding protein | 0.0211 | 0.264 | 0.264 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0076 | 0.0121 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0012 | 0.0017 | 0.0026 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0148 | 0.0479 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0027 | 0.0223 | 0.0223 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0324 | 0.0324 |
Brugia malayi | ecdysteroid receptor | 0.0022 | 0.0155 | 0.0247 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0017 | 0.0081 | 0.0081 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0022 | 0.0148 | 0.0479 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0022 | 0.0155 | 0.0155 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0022 | 0.0155 | 0.0247 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0027 | 0.0223 | 0.0223 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.