Detailed information for compound 697819

Basic information

Technical information
  • TDR Targets ID: 697819
  • Name: N-[2-[2-(4-fluorophenyl)-6-methyl-[1,3]thiazo lo[2,3-e][1,2,4]triazol-5-yl]ethyl]-3,5-dimet hylbenzamide
  • MW: 408.492 | Formula: C22H21FN4OS
  • H donors: 1 H acceptors: 3 LogP: 5.01 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1)c1nn2c(n1)sc(c2C)CCNC(=O)c1cc(C)cc(c1)C
  • InChi: 1S/C22H21FN4OS/c1-13-10-14(2)12-17(11-13)21(28)24-9-8-19-15(3)27-22(29-19)25-20(26-27)16-4-6-18(23)7-5-16/h4-7,10-12H,8-9H2,1-3H3,(H,24,28)
  • InChiKey: XSIJJKNJAPTZHI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[2-[2-(4-fluorophenyl)-6-methyl-thiazolo[2,3-e][1,2,4]triazol-5-yl]ethyl]-3,5-dimethyl-benzamide
  • N-[2-[2-(4-fluorophenyl)-6-methyl-5-thiazolo[2,3-e][1,2,4]triazolyl]ethyl]-3,5-dimethylbenzamide
  • N-[2-[2-(4-fluorophenyl)-6-methyl-[1,3]thiazolo[2,3-e][1,2,4]triazol-5-yl]ethyl]-3,5-dimethyl-benzamide
  • ZINC04570238

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus mothers against decapentaplegic 5 0.0032 0.0186 0.0186
Schistosoma mansoni pyruvate kinase 0.021 0.2294 0.2294
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0375 0.1432
Loa Loa (eye worm) hypothetical protein 0.0036 0.023 0.0216
Giardia lamblia Pyruvate kinase 0.021 0.2294 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0115 0.018
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0325 0.1338
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0183 0.1981 0.1981
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0126 0.0199
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0115 0.018
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0156 0.0156
Schistosoma mansoni inositol monophosphatase 0.0078 0.0732 0.0732
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.1123 0.1766
Onchocerca volvulus Pyruvate kinase homolog 0.021 0.2294 0.8703
Schistosoma mansoni hypothetical protein 0.0081 0.0765 0.0765
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0571 0.0571
Echinococcus multilocularis pyruvate kinase 0.021 0.2294 0.2294
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0183 0.1981 0.1981
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0375 0.1432
Schistosoma mansoni alpha-glucosidase 0.0284 0.318 0.318
Brugia malayi MH1 domain containing protein 0.0032 0.0186 0.0172
Trichomonas vaginalis pyruvate kinase, putative 0.021 0.2294 0.3609
Brugia malayi steroid hormone receptor 0.003 0.0156 0.0142
Brugia malayi ecdysteroid receptor 0.003 0.0156 0.0142
Loa Loa (eye worm) inositol-1 0.0078 0.0732 0.0719
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0073 0.0673 0.1059
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0325 0.0325
Mycobacterium leprae Probable pyruvate kinase PykA 0.021 0.2294 1
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0032 0.0186 0.0186
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.023 0.092
Loa Loa (eye worm) hypothetical protein 0.0111 0.1123 0.111
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0156 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0249 0.0391
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0021 0.0007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0156 0.0142
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0571 0.2418
Brugia malayi jmjC domain containing protein 0.0035 0.0221 0.0208
Loa Loa (eye worm) hypothetical protein 0.0483 0.554 0.5533
Echinococcus multilocularis inositol monophosphatase 1 0.0078 0.0732 0.0732
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0063 0.0556 0.0543
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0123 0.1259 0.1246
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0256 0.2845 0.2835
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0081 0.0765 0.0752
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0156 0.0156
Onchocerca volvulus Pyruvate kinase homolog 0.021 0.2294 0.8703
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0218 0.0343
Brugia malayi beta-lactamase family protein 0.0111 0.1123 0.111
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0156 0.0142
Trichomonas vaginalis inositol monophosphatase, putative 0.0078 0.0732 0.1152
Echinococcus granulosus pyruvate kinase 0.0108 0.1081 0.1081
Loa Loa (eye worm) pyruvate kinase 0.021 0.2294 0.2283
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0375 0.0361
Schistosoma mansoni tar DNA-binding protein 0.0859 1 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0156 0.0142
Schistosoma mansoni hypothetical protein 0.0081 0.0765 0.0765
Trichomonas vaginalis set domain proteins, putative 0.0237 0.2617 0.4117
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.1123 0.4847
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0111 0.1123 0.111
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0375 0.1634
Brugia malayi PHD-finger family protein 0.0029 0.0148 0.0135
Schistosoma mansoni smad1 5 8 and 0.0032 0.0186 0.0186
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0183 0.1981 0.1981
Echinococcus granulosus tumor protein p63 0.0718 0.8334 0.8334
Schistosoma mansoni thyroid hormone receptor 0.003 0.0156 0.0156
Mycobacterium tuberculosis Probable hydrolase 0.0111 0.1123 0.1363
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0078 0.0732 0.2878
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.2275 0.2264
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0156 0.0119
Loa Loa (eye worm) hypothetical protein 0.0048 0.0375 0.0361
Schistosoma mansoni coup transcription factor 0.003 0.0156 0.0156
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0123 0.1259 0.1246
Brugia malayi acetyltransferase, GNAT family protein 0.0153 0.1624 0.1612
Brugia malayi MH2 domain containing protein 0.0474 0.543 0.5424
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0156 0.0156
Plasmodium falciparum phd finger protein, putative 0.0029 0.0148 0.0561
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0325 0.0511
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0673 0.1059
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0218 0.0869
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0325 0.1231
Onchocerca volvulus 0.0105 0.1051 0.3712
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0338 0.0532
Loa Loa (eye worm) beta-lactamase 0.0111 0.1123 0.111
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0338 0.0532
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0673 0.2869
Leishmania major alpha glucosidase II subunit, putative 0.0073 0.0673 0.2869
Loa Loa (eye worm) hypothetical protein 0.0036 0.023 0.0216
Loa Loa (eye worm) RNA binding protein 0.0859 1 1
Echinococcus multilocularis GPCR, family 2 0.0081 0.0765 0.0765
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0123 0.1259 0.1246
Onchocerca volvulus 0.003 0.0156 0.0119
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0293 0.1102
Trichomonas vaginalis sucrase-isomaltase, putative 0.0073 0.0673 0.1059
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0078 0.0732 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.0375 0.0455
Echinococcus granulosus pyruvate kinase 0.0108 0.1081 0.1081
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0148 0.0148
Giardia lamblia PHD finger protein 15 0.0029 0.0148 0.0561
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0156 0.0142
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0571 0.0557
Brugia malayi hypothetical protein 0.0483 0.554 0.5533
Loa Loa (eye worm) hypothetical protein 0.0123 0.1259 0.1246
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0157 0.0157
Echinococcus multilocularis geminin 0.0348 0.3929 0.3929
Echinococcus multilocularis pyruvate kinase 0.0108 0.1081 0.1081
Echinococcus granulosus histone acetyltransferase KAT2B 0.0149 0.1573 0.1573
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0156 0.0156
Loa Loa (eye worm) hypothetical protein 0.0111 0.1123 0.111
Brugia malayi MH1 domain containing protein 0.0032 0.0186 0.0172
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0153 0.0241
Plasmodium vivax pyruvate kinase, putative 0.021 0.2294 1
Schistosoma mansoni inositol monophosphatase 0.0078 0.0732 0.0732
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0156 0.0142
Loa Loa (eye worm) hypothetical protein 0.0111 0.1123 0.111
Loa Loa (eye worm) hypothetical protein 0.0048 0.0375 0.0361
Brugia malayi Pyruvate kinase, muscle isozyme 0.021 0.2294 0.2283
Plasmodium falciparum pyruvate kinase 0.021 0.2294 1
Leishmania major pyruvate kinase 0.021 0.2294 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0375 0.1557
Schistosoma mansoni pyruvate kinase 0.0108 0.1081 0.1081
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0156 0.0156
Brugia malayi nuclear receptor NHR-88 0.003 0.0156 0.0142
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0183 0.1981 0.1981
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0148 0.0148
Leishmania major glycosyl hydrolase-like protein 0.0027 0.0126 0.0464
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.1123 0.1766
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.023 0.092
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0126 0.0199
Schistosoma mansoni tar DNA-binding protein 0.0859 1 1
Mycobacterium tuberculosis Probable lipase LipE 0.0111 0.1123 0.1363
Schistosoma mansoni glutaminase 0.0552 0.6355 0.6355
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0126 0.0199
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.1123 0.1766
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0148 0.0561
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.1123 0.1766
Echinococcus granulosus pyruvate kinase 0.021 0.2294 0.2294
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0157 0.0157
Brugia malayi TAR-binding protein 0.0859 1 1
Echinococcus multilocularis tumor protein p63 0.0718 0.8334 0.8334
Schistosoma mansoni hypothetical protein 0.0099 0.0972 0.0972
Toxoplasma gondii pyruvate kinase PyK1 0.021 0.2294 1
Loa Loa (eye worm) TAR-binding protein 0.0859 1 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.0937 0.0937
Entamoeba histolytica hypothetical protein 0.0227 0.2492 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0183 0.1981 0.1981
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0156 0.0156
Brugia malayi beta-lactamase family protein 0.0111 0.1123 0.111
Echinococcus granulosus FTZ F1 alpha 0.003 0.0156 0.0156
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0123 0.1259 0.5446
Echinococcus granulosus inositol monophosphatase 1 0.0078 0.0732 0.0732
Loa Loa (eye worm) hypothetical protein 0.0175 0.1882 0.1871
Brugia malayi Inositol-1 0.0078 0.0732 0.0719
Entamoeba histolytica pyruvate kinase, putative 0.0146 0.154 0.6147
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0375 0.059
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0157 0.0157
Trypanosoma cruzi pyruvate kinase 2, putative 0.021 0.2294 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0021 0.0033
Mycobacterium tuberculosis Conserved protein 0.0111 0.1123 0.1363
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0375 0.059
Brugia malayi Pyruvate kinase, M2 isozyme 0.021 0.2294 0.2283
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0084 0.0133
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0156 0.0142
Brugia malayi hypothetical protein 0.0227 0.2492 0.2481
Echinococcus multilocularis pyruvate kinase 0.0108 0.1081 0.1081
Schistosoma mansoni pyruvate kinase 0.021 0.2294 0.2294
Echinococcus multilocularis Smad4 0.0032 0.0186 0.0186
Echinococcus granulosus TGF beta signal transducer SmadC 0.0032 0.0186 0.0186
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0156 0.0142
Schistosoma mansoni tar DNA-binding protein 0.0859 1 1
Echinococcus granulosus GPCR family 2 0.0081 0.0765 0.0765
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0156 0.0142
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0156 0.0156
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0338 0.1394
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0375 0.059
Onchocerca volvulus 0.0099 0.0972 0.3397
Echinococcus multilocularis peregrin 0.0033 0.0193 0.0193
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0156 0.0156
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0021 0.0007
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0156 0.0156
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0673 0.2869
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0021 0.0286
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0156 0.0156
Loa Loa (eye worm) pyruvate kinase 0.0044 0.0327 0.0313
Loa Loa (eye worm) glutaminase 0.0552 0.6355 0.635
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0123 0.1259 0.1259
Schistosoma mansoni ap endonuclease 0.0018 0.0021 0.0021
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0081 0.0765 0.0765
Loa Loa (eye worm) pyruvate kinase 0.021 0.2294 0.2283
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0156 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0325 0.0511
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0156 0.0156
Echinococcus multilocularis mothers against decapentaplegic 5 0.0032 0.0186 0.0186
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0021 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0156 0.0142
Loa Loa (eye worm) hypothetical protein 0.003 0.0156 0.0142
Schistosoma mansoni thyroid hormone receptor 0.003 0.0156 0.0156
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0859 1 1
Brugia malayi Pre-SET motif family protein 0.0208 0.2275 0.2264
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0081 0.0765 0.0765
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0142 0.0223
Loa Loa (eye worm) hypothetical protein 0.0256 0.2845 0.2835
Schistosoma mansoni smad1 5 8 and 0.0032 0.0186 0.0186
Loa Loa (eye worm) pyruvate kinase 0.021 0.2294 0.2283
Echinococcus multilocularis microtubule associated protein 2 0.069 0.8002 0.8002
Brugia malayi MH2 domain containing protein 0.0032 0.0186 0.0172
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0207 0.0251
Leishmania major pyruvate kinase 0.021 0.2294 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0673 0.1059
Toxoplasma gondii pyruvate kinase PyKII 0.0108 0.1081 0.4664
Echinococcus granulosus lysosomal alpha glucosidase 0.033 0.3727 0.3727
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0293 0.1198
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0126 0.0464
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0148 0.0148
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0123 0.1259 0.5446
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0218 0.0876
Brugia malayi nuclear hormone receptor 0.003 0.0156 0.0142
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0325 0.1338
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0126 0.0199
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0207 0.0251
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0191 0.0748
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.033 0.3727 0.3718
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0221 0.0221
Mycobacterium ulcerans pyruvate kinase 0.021 0.2294 0.3609
Schistosoma mansoni ap endonuclease 0.0018 0.0021 0.0021
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.021 0.2294 0.2784
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0084 0.0132
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0325 0.0311
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0156 0.0156
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0191 0.0301
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0021 0.0025
Loa Loa (eye worm) latrophilin receptor protein 2 0.0081 0.0765 0.0752
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0123 0.1259 0.5446
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0111 0.1123 0.1363
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0032 0.0186 0.0186
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0073 0.0673 0.066
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0156 0.0156
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0732 0.1152
Chlamydia trachomatis pyruvate kinase 0.021 0.2294 1
Schistosoma mansoni microtubule-associated protein tau 0.069 0.8002 0.8002
Echinococcus multilocularis tar DNA binding protein 0.0859 1 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0081 0.0765 0.0765
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0207 0.0251
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0156 0.0142
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0156 0.0156
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.1123 0.1123
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0156 0.0142
Echinococcus multilocularis lysosomal alpha glucosidase 0.033 0.3727 0.3727
Mycobacterium tuberculosis Possible penicillin-binding protein 0.071 0.8239 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0111 0.1123 0.1363
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0111 0.0175
Brugia malayi latrophilin 2 splice variant baaae 0.0175 0.1882 0.1871
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0156 0.0156
Mycobacterium ulcerans beta-lactamase 0.0111 0.1123 0.1766
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0673 0.1059
Loa Loa (eye worm) hypothetical protein 0.021 0.2294 0.2283
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0073 0.0673 0.2869
Loa Loa (eye worm) hypothetical protein 0.0036 0.023 0.0216
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0207 0.0251
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0325 0.0325
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0156 0.0142
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.007 0.0635 0.077
Trypanosoma cruzi pyruvate kinase 2, putative 0.021 0.2294 1
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0571 0.0557
Loa Loa (eye worm) hypothetical protein 0.005 0.0396 0.0382
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0191 0.0301
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0021 0.0021
Giardia lamblia Pyruvate kinase 0.0108 0.1081 0.4664
Trypanosoma brucei hypothetical protein, conserved 0.0111 0.1123 0.4851
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0126 0.0199
Plasmodium vivax hypothetical protein, conserved 0.0111 0.1123 0.4847
Echinococcus granulosus smad 0.0032 0.0186 0.0186
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0144 0.0144
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0571 0.2418
Loa Loa (eye worm) hypothetical protein 0.003 0.0156 0.0142
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0157 0.0157
Mycobacterium ulcerans lipase LipD 0.0111 0.1123 0.1766
Mycobacterium tuberculosis Probable lipase LipD 0.0111 0.1123 0.1363
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.007 0.0635 0.2767
Brugia malayi Glycosyl hydrolases family 31 protein 0.033 0.3727 0.3718
Schistosoma mansoni Smad4 0.0032 0.0186 0.0186
Schistosoma mansoni hypothetical protein 0.0348 0.3929 0.3929
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0156 0.0142
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.023 0.0279
Schistosoma mansoni hypothetical protein 0.0175 0.1882 0.1882
Brugia malayi Glycosyl hydrolases family 31 protein 0.0027 0.0126 0.0112
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0156 0.0156
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0571 0.2224
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0148 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0084 0.0133
Schistosoma mansoni tar DNA-binding protein 0.0859 1 1
Schistosoma mansoni smad 0.0032 0.0186 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0156 0.0142
Loa Loa (eye worm) transcription factor SMAD2 0.0474 0.543 0.5424
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0375 0.0361
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0156 0.0156
Schistosoma mansoni hypothetical protein 0.0227 0.2492 0.2492
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0021 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0021 0.0007
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0021 0.0021
Brugia malayi hypothetical protein 0.0111 0.1117 0.1105
Onchocerca volvulus 0.0048 0.0375 0.0998
Echinococcus granulosus peregrin 0.0033 0.0193 0.0193
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0227 0.2492 0.2492
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0191 0.0301
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0218 0.0343
Echinococcus granulosus neutral alpha glucosidase AB 0.0073 0.0673 0.0673
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0156 0.0156
Trypanosoma brucei glycosyl hydrolase-like protein 0.0027 0.0126 0.0471
Trypanosoma brucei pyruvate kinase 1, putative 0.021 0.2294 1
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0156 0.0142
Schistosoma mansoni tar DNA-binding protein 0.0859 1 1
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0126 0.0464
Schistosoma mansoni transcription factor LCR-F1 0.0227 0.2492 0.2492
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0084 0.0133
Schistosoma mansoni hypothetical protein 0.0029 0.0148 0.0148
Brugia malayi glutaminase DH11.1 0.0552 0.6355 0.635
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0148 0.0561
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0156 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0218 0.0343
Mycobacterium tuberculosis Conserved protein 0.0111 0.1123 0.1363
Brugia malayi MH2 domain containing protein 0.0032 0.0186 0.0172
Schistosoma mansoni alpha glucosidase 0.0073 0.0673 0.0673
Plasmodium vivax pyruvate kinase 2, putative 0.0108 0.1081 0.4664
Loa Loa (eye worm) hypothetical protein 0.003 0.0157 0.0143
Toxoplasma gondii ABC1 family protein 0.0111 0.1123 0.4847
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0049 0.0132
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0027 0.0126 0.0427
Loa Loa (eye worm) hypothetical protein 0.0111 0.1123 0.111
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0156 0.0156
Onchocerca volvulus Alhambra homolog 0.0029 0.0148 0.0089
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0156 0.0142
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0156 0.0156
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.0937 0.0937
Loa Loa (eye worm) glutaminase 2 0.0552 0.6355 0.635
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0732 0.3134
Mycobacterium ulcerans hypothetical protein 0.0048 0.0375 0.059
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0153 0.1624 0.1624
Leishmania major hypothetical protein, conserved 0.0111 0.1123 0.4847
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0156 0.0156
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0126 0.0199
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0156 0.0156
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0571 0.2418
Schistosoma mansoni smad1 5 8 and 0.0032 0.0186 0.0186
Echinococcus granulosus microtubule associated protein 2 0.069 0.8002 0.8002
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0325 0.1338
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0115 0.018
Schistosoma mansoni nuclear hormone receptor 0.003 0.0156 0.0156
Schistosoma mansoni cellular tumor antigen P53 0.0105 0.1051 0.1051
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0156 0.0142
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0571 0.0571
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0156 0.0142
Mycobacterium ulcerans hypothetical protein 0.0111 0.1123 0.1766
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0021 0.0033
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0325 0.0311
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0111 0.0175
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0338 0.1394
Trichomonas vaginalis pyruvate kinase, putative 0.021 0.2294 0.3609
Echinococcus granulosus geminin 0.0348 0.3929 0.3929
Trichomonas vaginalis esterase, putative 0.0111 0.1123 0.1766
Schistosoma mansoni hypothetical protein 0.0348 0.3929 0.3929
Loa Loa (eye worm) acetyltransferase 0.0153 0.1624 0.1612
Trichomonas vaginalis maltase-glucoamylase, putative 0.0073 0.0673 0.1059
Onchocerca volvulus Pyruvate kinase homolog 0.021 0.2294 0.8703
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0221 0.0208
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.0375 0.059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0218 0.0343
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0048 0.0375 0.059
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0218 0.0869
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0325 0.1344
Echinococcus granulosus survival motor neuron protein 1 0.0483 0.554 0.554
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0111 0.1123 0.1363
Schistosoma mansoni hypothetical protein 0.0123 0.1259 0.1259
Schistosoma mansoni survival motor neuron protein 0.0099 0.0972 0.0972
Mycobacterium ulcerans esterase/lipase LipP 0.0111 0.1123 0.1766
Plasmodium falciparum pyruvate kinase 2 0.0108 0.1081 0.4664
Loa Loa (eye worm) hypothetical protein 0.003 0.0156 0.0142
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0156 0.0156
Echinococcus multilocularis pyruvate kinase 0.0108 0.1081 0.1081
Trypanosoma brucei pyruvate kinase 1 0.021 0.2294 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0032 0.0186 0.0172
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0111 0.1123 0.111
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0703 0.0703
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0156 0.0142
Plasmodium vivax SET domain protein, putative 0.003 0.0157 0.0598
Schistosoma mansoni hypothetical protein 0.0081 0.0765 0.0765
Echinococcus multilocularis survival motor neuron protein 1 0.0483 0.554 0.554
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0284 0.0284
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0325 0.0325
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0157 0.0157
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0732 0.3129
Loa Loa (eye worm) hypothetical protein 0.0111 0.1123 0.111
Loa Loa (eye worm) hypothetical protein 0.0081 0.0765 0.0752
Loa Loa (eye worm) pyruvate kinase-PB 0.0146 0.154 0.1528
Onchocerca volvulus 0.0191 0.2072 0.7813
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0247 0.0247
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0156 0.0142
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0157 0.0157
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0375 0.1634
Brugia malayi hypothetical protein 0.0111 0.1117 0.1105
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0517 0.0504
Loa Loa (eye worm) MH1 domain-containing protein 0.0032 0.0186 0.0172
Loa Loa (eye worm) hypothetical protein 0.0111 0.1123 0.111
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0247 0.0247
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0183 0.1981 0.1981
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0571 0.2424
Loa Loa (eye worm) hypothetical protein 0.003 0.0156 0.0142
Brugia malayi Bromodomain containing protein 0.0033 0.0193 0.0179
Brugia malayi Pre-SET motif family protein 0.003 0.0157 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0084 0.0132
Loa Loa (eye worm) hypothetical protein 0.0029 0.0148 0.0135
Entamoeba histolytica hypothetical protein 0.0227 0.2492 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0157 0.0598
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0183 0.1981 0.1969
Echinococcus granulosus pyruvate kinase 0.021 0.2294 0.2294
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0078 0.0732 0.1152
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0256 0.2845 0.2835
Echinococcus multilocularis smad 0.0032 0.0186 0.0186
Trypanosoma brucei glucosidase, putative 0.0073 0.0673 0.2874
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0673 0.1059
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0048 0.0375 0.0455
Loa Loa (eye worm) hypothetical protein 0.0048 0.0375 0.0361
Brugia malayi Calcitonin receptor-like protein seb-1 0.0256 0.2845 0.2835
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0183 0.1981 0.1981
Brugia malayi RNA recognition motif domain containing protein 0.0859 1 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0221 0.0221
Mycobacterium leprae conserved hypothetical protein 0.0111 0.1123 0.4894
Echinococcus multilocularis beta LACTamase domain containing family member 0.0111 0.1123 0.1123
Loa Loa (eye worm) hypothetical protein 0.0036 0.023 0.0216
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0084 0.0132
Brugia malayi pyruvate kinase, muscle isozyme 0.0044 0.0327 0.0313
Loa Loa (eye worm) hypothetical protein 0.003 0.0156 0.0142
Echinococcus granulosus pyruvate kinase 0.0108 0.1081 0.1081
Brugia malayi pyruvate kinase 0.0044 0.0327 0.0313
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0156 0.0156
Echinococcus granulosus beta LACTamase domain containing family member 0.0111 0.1123 0.1123
Echinococcus granulosus lysine specific demethylase 5A 0.0035 0.0221 0.0221
Brugia malayi Smad1 0.0032 0.0186 0.0172
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0073 0.0673 0.2639
Trichomonas vaginalis glutaminase, putative 0.0552 0.6355 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.0112
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0571 0.0571
Mycobacterium leprae Probable lipase LipE 0.0111 0.1123 0.4894
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0375 0.1557
Loa Loa (eye worm) hypothetical protein 0.0036 0.023 0.0216
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0078 0.0732 0.1152
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0148 0.0561
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0156 0.0156
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0338 0.1394
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0153 0.1624 0.1624
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0791 0.92 0.92
Mycobacterium tuberculosis Conserved protein 0.0111 0.1123 0.1363
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0157 0.0157
Echinococcus multilocularis lysosomal alpha glucosidase 0.033 0.3727 0.3727
Loa Loa (eye worm) hypothetical protein 0.003 0.0156 0.0142
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.023 0.0362
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0325 0.0511
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0156 0.0142
Loa Loa (eye worm) Smad1 0.0032 0.0186 0.0172
Entamoeba histolytica hypothetical protein 0.0227 0.2492 1
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0078 0.0732 0.3129
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0156 0.0142
Loa Loa (eye worm) hypothetical protein 0.0105 0.1051 0.1038
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.1123 0.4847
Schistosoma mansoni hypothetical protein 0.0081 0.0765 0.0765
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0126 0.0199
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0673 0.1059
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0325 0.1344
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0293 0.1198
Onchocerca volvulus 0.0111 0.1123 0.4
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0375 0.0361
Onchocerca volvulus 0.0237 0.2617 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0073 0.0673 0.1059
Onchocerca volvulus 0.003 0.0157 0.0122
Loa Loa (eye worm) hypothetical protein 0.0146 0.154 0.1528
Mycobacterium tuberculosis Probable esterase LipL 0.0111 0.1123 0.1363
Brugia malayi Glycosyl hydrolases family 31 protein 0.0073 0.0673 0.066
Giardia lamblia GTOR 0.0044 0.0325 0.1338
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0183 0.1981 0.1969
Echinococcus multilocularis neutral alpha glucosidase AB 0.0073 0.0673 0.0673
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0338 0.0338
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0218 0.0343
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0284 0.0284
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0191 0.0301
Echinococcus granulosus Smad4 0.0032 0.0186 0.0186
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0073 0.0673 0.2639
Onchocerca volvulus 0.0111 0.1123 0.4
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.1123 0.1123
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0156 0.0142
Echinococcus granulosus tar DNA binding protein 0.0859 1 1
Schistosoma mansoni alpha-glucosidase 0.0284 0.318 0.318
Brugia malayi Latrophilin receptor protein 2 0.0081 0.0765 0.0752
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.1123 0.1766
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0084 0.0133
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0325 0.1338
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0156 0.0142
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0732 0.3129
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0048 0.0375 0.059
Echinococcus multilocularis pyruvate kinase 0.021 0.2294 0.2294
Trichomonas vaginalis maltase-glucoamylase, putative 0.0027 0.0126 0.0199
Onchocerca volvulus 0.0111 0.1123 0.4
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0048 0.0375 0.059
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0375 0.1557
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0191 0.0301
Entamoeba histolytica hypothetical protein 0.0227 0.2492 1
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0325 0.1231
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0081 0.0765 0.0765
Mycobacterium ulcerans glutaminase 0.0552 0.6355 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0156 0.0156
Echinococcus multilocularis pyruvate kinase 0.0166 0.1769 0.1769
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0191 0.0301
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0111 0.1123 0.1766
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0191 0.0301
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0078 0.0732 0.3129
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0227 0.2492 0.2492
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.003 0.0156 0.0142
Brugia malayi beta-lactamase 0.0111 0.1123 0.111
Entamoeba histolytica acyl-coA synthetase, putative 0.0048 0.0375 0.1432
Brugia malayi jmjC domain containing protein 0.0096 0.0937 0.0924
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0099 0.0972 0.096
Loa Loa (eye worm) MH2 domain-containing protein 0.0474 0.543 0.5424

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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