Detailed information for compound 697852

Basic information

Technical information
  • TDR Targets ID: 697852
  • Name: ZINC04570198
  • MW: 376.857 | Formula: C18H17ClN2O3S
  • H donors: 1 H acceptors: 3 LogP: 2.86 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1Cc2c3N1CCCc3cc(c2)S(=O)(=O)Nc1ccc(c(c1)Cl)C
  • InChi: 1S/C18H17ClN2O3S/c1-11-4-5-14(10-16(11)19)20-25(23,24)15-7-12-3-2-6-21-17(22)9-13(8-15)18(12)21/h4-5,7-8,10,20H,2-3,6,9H2,1H3
  • InChiKey: LUWJMZQTOIZNKW-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0044 0.0042
Mycobacterium ulcerans hypothetical protein 0.0072 0.0731 0.247
Loa Loa (eye worm) TAR-binding protein 0.0506 0.5656 1
Schistosoma mansoni smad1 5 8 and 0.0008 0.0009 0.0011
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0477 0.0839
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.0731 0.1288
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0132 0.1422 0.1671
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0153 0.0151
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0043 0.0412 0.0725
Brugia malayi MH1 domain containing protein 0.0008 0.0009 0.0012
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0089 0.0102
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.3104 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0044 0.0075
Schistosoma mansoni smad1 5 8 and 0.0008 0.0009 0.0011
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.0731 0.1428
Loa Loa (eye worm) hypothetical protein 0.0011 0.0044 0.0075
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0136 0.0161
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0043 0.0407 0.048
Loa Loa (eye worm) pyruvate kinase 0.0132 0.1415 0.2499
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.3104 1
Echinococcus granulosus dna polymerase kappa 0.0019 0.0138 0.016
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0044 0.0075
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0602 0.106
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0136 0.0134
Brugia malayi hypothetical protein 0.0019 0.0136 0.0237
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0068 0.0212
Plasmodium falciparum pyruvate kinase 0.0132 0.1415 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0132 0.1422 0.2784
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.0407 0.1313
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0431 0.0429
Brugia malayi RNA binding protein 0.0506 0.5656 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0457 0.5101 1
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0138 0.0136
Loa Loa (eye worm) hypothetical protein 0.0072 0.0731 0.1288
Leishmania major DNA polymerase eta, putative 0.0019 0.0138 0.0437
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0477 0.0839
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0009 0.0012
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0136 0.0237
Onchocerca volvulus 0.0054 0.0528 0.1695
Schistosoma mansoni tar DNA-binding protein 0.0506 0.5656 0.6655
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0136 0.0433
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0044 0.0052
Brugia malayi Smad1 0.0008 0.0009 0.0012
Echinococcus granulosus pyruvate kinase 0.0132 0.1415 0.1663
Echinococcus granulosus pyruvate kinase 0.0132 0.1415 0.1663
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0096 0.0094
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0074 0.0232
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0318 0.1017
Onchocerca volvulus 0.0072 0.0731 0.2348
Loa Loa (eye worm) hypothetical protein 0.0072 0.0731 0.1288
Trypanosoma brucei pyruvate kinase 1, putative 0.0132 0.1415 0.4554
Schistosoma mansoni pyruvate kinase 0.0132 0.1415 0.1665
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0074 0.0232
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0138 0.0266
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0009 0.0007
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0009 0.0007
Chlamydia trachomatis pyruvate kinase 0.0132 0.1415 0.5
Loa Loa (eye worm) hypothetical protein 0.0011 0.0044 0.0075
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.0002 0.0003
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0128 0.0222
Schistosoma mansoni tar DNA-binding protein 0.0506 0.5656 0.6655
Loa Loa (eye worm) RNA binding protein 0.0506 0.5656 1
Loa Loa (eye worm) pyruvate kinase-PB 0.0092 0.0963 0.1699
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.1714 0.3028
Loa Loa (eye worm) hypothetical protein 0.0019 0.0136 0.0237
Loa Loa (eye worm) hypothetical protein 0.0011 0.0044 0.0075
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.1714 0.3028
Schistosoma mansoni DNA polymerase eta 0.0019 0.0138 0.0162
Onchocerca volvulus Pyruvate kinase homolog 0.0132 0.1415 0.4554
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0044 0.005
Mycobacterium ulcerans pyruvate kinase 0.0132 0.1415 0.4792
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0281 0.3104 0.3651
Brugia malayi glutaminase DH11.1 0.0267 0.2951 0.5215
Trypanosoma brucei pyruvate kinase 1 0.0132 0.1415 0.4554
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.1251 0.88
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0153 0.1084
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0138 0.0437
Onchocerca volvulus 0.006 0.0602 0.1932
Onchocerca volvulus 0.0072 0.0731 0.2348
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0136 0.0161
Echinococcus multilocularis smad 0.0008 0.0009 0.0007
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0138 0.0437
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0136 0.0158
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0318 0.1017
Mycobacterium tuberculosis Conserved protein 0.0072 0.0731 0.1428
Schistosoma mansoni kinase 0.0143 0.1538 0.181
Schistosoma mansoni tar DNA-binding protein 0.0506 0.5656 0.6655
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0043 0.0412 0.2052
Plasmodium falciparum pyruvate kinase 2 0.0068 0.0687 0.4856
Trichomonas vaginalis hypothetical protein 0.0007 0.0002 0.0001
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0096 0.0166
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0153 0.0487
Schistosoma mansoni smad 0.0008 0.0009 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0074 0.0232
Loa Loa (eye worm) Smad1 0.0008 0.0009 0.0012
Leishmania major importin beta-1 subunit, putative 0.0024 0.0188 0.0599
Schistosoma mansoni coup transcription factor 0.0011 0.0044 0.0052
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0506 0.5656 1
Schistosoma mansoni cpg binding protein 0.0064 0.064 0.0754
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0731 0.2348
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0044 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0138 0.0437
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0044 0.0075
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0044 0.0042
Mycobacterium ulcerans glutaminase 0.0267 0.2951 1
Mycobacterium tuberculosis Conserved protein 0.0072 0.0731 0.1428
Schistosoma mansoni hypothetical protein 0.0147 0.1586 0.1867
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0318 0.1017
Schistosoma mansoni cpg binding protein 0.006 0.0602 0.0708
Loa Loa (eye worm) hypothetical protein 0.0013 0.0068 0.0116
Echinococcus granulosus dnaJ subfamily B 0.0448 0.5004 0.5888
Trichomonas vaginalis CAMK family protein kinase 0.0139 0.1496 0.4816
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.0731 0.0857
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.007 0.0219
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0044 0.0052
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0136 0.0134
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0136 0.0161
Trypanosoma brucei glucosidase, putative 0.0035 0.0318 0.1017
Mycobacterium tuberculosis Conserved protein 0.0072 0.0731 0.1428
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0017 0.002
Echinococcus multilocularis Smad4 0.0008 0.0009 0.0007
Onchocerca volvulus Pyruvate kinase homolog 0.0132 0.1415 0.4554
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0731 0.5155
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0044 0.0075
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0068 0.0212
Loa Loa (eye worm) hypothetical protein 0.0092 0.0963 0.1699
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.3104 1
Trichomonas vaginalis glutaminase, putative 0.0267 0.2951 0.9505
Echinococcus granulosus snurportin 1 0.0312 0.3452 0.4061
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0044 0.0075
Loa Loa (eye worm) hypothetical protein 0.0011 0.0044 0.0075
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0132 0.1422 0.142
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0044 0.0075
Mycobacterium leprae Probable pyruvate kinase PykA 0.0132 0.1415 1
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0147 0.0173
Trypanosoma brucei polo-like protein kinase 0.0281 0.3104 1
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0043 0.0412 0.0725
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0431 0.0504
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0407 0.1306
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0044 0.0042
Loa Loa (eye worm) pyruvate kinase 0.0132 0.1415 0.2499
Entamoeba histolytica hypothetical protein 0.0024 0.0188 0.0605
Loa Loa (eye worm) hypothetical protein 0.0043 0.0407 0.0717
Brugia malayi hypothetical protein 0.0039 0.0364 0.0641
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0044 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0138 0.0437
Schistosoma mansoni glutaminase 0.0267 0.2951 0.3472
Trichomonas vaginalis maltase-glucoamylase, putative 0.0013 0.0068 0.0212
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0044 0.005
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0136 0.0237
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0136 0.0161
Trypanosoma cruzi pyruvate kinase 2, putative 0.0132 0.1415 0.4554
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0407 0.1306
Echinococcus granulosus histone acetyltransferase KAT2B 0.0139 0.1494 0.1756
Mycobacterium leprae Probable lipase LipE 0.0072 0.0731 0.5155
Brugia malayi beta-lactamase 0.0072 0.0731 0.1288
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0007 0.0002 0.0007
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0138 0.0437
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.1714 0.1712
Giardia lamblia Kinase, PLK 0.0281 0.3104 1
Brugia malayi pyruvate kinase 0.0028 0.0235 0.0411
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0131 0.0128
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0136 0.0237
Brugia malayi steroid hormone receptor 0.0011 0.0044 0.0075
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0138 0.0437
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0153 1
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0074 0.0232
Schistosoma mansoni hypothetical protein 0.0448 0.5004 0.5889
Brugia malayi acetyltransferase, GNAT family protein 0.0143 0.1539 0.2719
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0044 0.0075
Schistosoma mansoni cpg binding protein 0.0064 0.064 0.0754
Trypanosoma brucei unspecified product 0.0019 0.0138 0.0437
Trichomonas vaginalis CAMK family protein kinase 0.0139 0.1496 0.4816
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0136 0.0433
Entamoeba histolytica hypothetical protein 0.0147 0.1586 0.511
Loa Loa (eye worm) hypothetical protein 0.0019 0.0136 0.0237
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0096 0.0166
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0396 0.1269
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0136 0.0161
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0407 0.0477
Echinococcus granulosus geminin 0.0169 0.184 0.2164
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0136 0.0158
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0153 0.0487
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0007 0.0002 0.0007
Onchocerca volvulus Serine\/threonine kinase homolog 0.0281 0.3104 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0089 0.0102
Trypanosoma cruzi polo-like protein kinase, putative 0.0281 0.3104 1
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0136 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0136 0.0433
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.1714 0.2015
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0136 0.0158
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0396 0.1269
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0138 0.0437
Brugia malayi nuclear receptor NHR-88 0.0011 0.0044 0.0075
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0136 0.0158
Toxoplasma gondii aldehyde dehydrogenase 0.0132 0.1422 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0153 0.0178
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0044 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0044 0.0075
Toxoplasma gondii ABC1 family protein 0.0072 0.0731 0.5131
Trichomonas vaginalis helicase, putative 0.0014 0.0074 0.0232
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0044 0.0075
Loa Loa (eye worm) hypothetical protein 0.0043 0.0412 0.0725
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0356 0.2517
Schistosoma mansoni hypothetical protein 0.0016 0.0096 0.0113
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0153 0.0487
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0407 0.0405
Echinococcus granulosus Smad4 0.0008 0.0009 0.0008
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0044 0.0136
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0009 0.0012
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0318 0.1024
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0188 0.0599
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0731 0.2348
Schistosoma mansoni hypothetical protein 0.0169 0.184 0.2166
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0153 0.0494
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0281 0.3104 0.3103
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0044 0.0075
Loa Loa (eye worm) hypothetical protein 0.0034 0.03 0.0528
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0407 0.1306
Loa Loa (eye worm) hypothetical protein 0.0049 0.0477 0.0839
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.0407 0.0717
Loa Loa (eye worm) hypothetical protein 0.0016 0.0096 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0074 0.0232
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0136 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0136 0.0433
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0136 0.0161
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0138 0.0437
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0138 0.024
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0043 0.0407 0.1306
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0147 0.1586 0.1864
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0318 0.1017
Schistosoma mansoni alpha-glucosidase 0.0136 0.1464 0.1723
Echinococcus multilocularis snurportin 1 0.0312 0.3452 0.3451
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.025 0.1749
Loa Loa (eye worm) pyruvate kinase 0.0132 0.1415 0.2499
Echinococcus multilocularis pyruvate kinase 0.0068 0.0687 0.0685
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0318 0.2224
Toxoplasma gondii pyruvate kinase PyK1 0.0132 0.1415 0.9954
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0136 0.0134
Schistosoma mansoni aldehyde dehydrogenase 0.0132 0.1422 0.1673
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.0731 0.1428
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0044 0.0075
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0731 0.086
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0318 0.0558
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0043 0.0407 0.1306
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0068 0.0212
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.007 0.0219
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0044 0.0075
Echinococcus multilocularis GPCR, family 2 0.0016 0.0096 0.0094
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.0731 0.247
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0147 0.017
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0143 0.1539 0.1537
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0153 0.0267
Echinococcus granulosus tumor protein p63 0.0367 0.4077 0.4797
Schistosoma mansoni serine/threonine protein kinase 0.0281 0.3104 0.3653
Loa Loa (eye worm) acetyltransferase 0.0143 0.1539 0.2719
Loa Loa (eye worm) hypothetical protein 0.0011 0.0044 0.0075
Echinococcus multilocularis importin subunit beta 1 0.0029 0.025 0.0248
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.0731 0.1428
Schistosoma mansoni hypothetical protein 0.0169 0.184 0.2166
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0407 0.0477
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0136 0.0158
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0044 0.0042
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.03 0.0528
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0136 0.0134
Leishmania major DNA polymerase kappa, putative 0.0019 0.0138 0.0437
Echinococcus multilocularis geminin 0.0169 0.184 0.1838
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0138 0.0162
Giardia lamblia Pyruvate kinase 0.0132 0.1415 0.4554
Brugia malayi beta-lactamase family protein 0.0072 0.0731 0.1288
Schistosoma mansoni hypothetical protein 0.0034 0.03 0.0354
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0074 0.0232
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0138 0.024
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0431 0.0507
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0153 0.0487
Brugia malayi MH2 domain containing protein 0.0008 0.0009 0.0012
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.1422 0.4814
Brugia malayi TAR-binding protein 0.0506 0.5656 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0089 0.0105
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0002 0.0001
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0318 0.0558
Brugia malayi hypothetical protein 0.0039 0.0364 0.0641
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0318 0.1017
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0044 0.0052
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0136 0.0161
Brugia malayi Importin beta-1 subunit 0.0029 0.025 0.0439
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0731 0.2348
Brugia malayi Pyruvate kinase, M2 isozyme 0.0132 0.1415 0.2499
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0044 0.0052
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.3104 1
Schistosoma mansoni ap endonuclease 0.0021 0.0153 0.018
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0013 0.0068 0.0219
Leishmania major pyruvate kinase 0.0132 0.1415 0.4554
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0068 0.0212
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0147 0.0256
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0407 0.0405
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0147 0.0173
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0096 0.0094
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0007 0.0002 0.0003
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0009 0.0008
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0318 0.1017
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0136 0.0433
Schistosoma mansoni alpha glucosidase 0.0035 0.0318 0.0374
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.0731 0.1428
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0153 0.0487
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0138 0.0266
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0044 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0138 0.0437
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.0731 0.1428
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0396 0.2774
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.025 0.08
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0138 0.0437
Toxoplasma gondii exonuclease III APE 0.0021 0.0153 0.1065
Plasmodium falciparum importin beta, putative 0.0029 0.025 0.177
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0731 0.2348
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.0731 0.0728
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.1714 0.1712
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0043 0.0412 0.0725
Loa Loa (eye worm) hypothetical protein 0.0019 0.0136 0.0237
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0044 0.005
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0147 0.0173
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0044 0.005
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0132 0.1415 0.2771
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0136 0.0158
Loa Loa (eye worm) hypothetical protein 0.0019 0.0136 0.0237
Brugia malayi PXA domain containing protein 0.0019 0.0136 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0074 0.0232
Trypanosoma brucei unspecified product 0.0013 0.007 0.0219
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.0731 0.1428
Plasmodium vivax pyruvate kinase 2, putative 0.0068 0.0687 0.4231
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.1235 0.218
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0138 0.016
Echinococcus granulosus dna polymerase eta 0.0019 0.0138 0.016
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0356 0.1141
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.0002 0.0003
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0138 0.0136
Schistosoma mansoni ap endonuclease 0.0021 0.0153 0.018
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0136 0.0237
Schistosoma mansoni pyruvate kinase 0.0068 0.0687 0.0809
Entamoeba histolytica hypothetical protein 0.0147 0.1586 0.511
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0431 0.0758
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0044 0.0052
Loa Loa (eye worm) hypothetical protein 0.0011 0.0044 0.0075
Loa Loa (eye worm) hypothetical protein 0.0054 0.0528 0.093
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0431 0.0507
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0044 0.0136
Schistosoma mansoni hypothetical protein 0.0312 0.3452 0.4062
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0074 0.0232
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0089 0.0087
Schistosoma mansoni microtubule-associated protein tau 0.0757 0.8498 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0138 0.024
Trypanosoma brucei unspecified product 0.0013 0.007 0.0219
Brugia malayi MH1 domain containing protein 0.0008 0.0009 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0074 0.0232
Mycobacterium ulcerans lipase LipD 0.0072 0.0731 0.247
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0044 0.0052
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.0002 0.0003
Echinococcus multilocularis expressed protein 0.0372 0.4143 0.4142
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0431 0.0504
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0044 0.0075
Schistosoma mansoni hypothetical protein 0.0043 0.0412 0.0485
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0431 0.0429
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0731 0.2348
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.1235 0.218
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0138 0.0437
Echinococcus multilocularis microtubule associated protein 2 0.0757 0.8498 0.8498
Trypanosoma cruzi pyruvate kinase 2, putative 0.0132 0.1415 0.4554
Brugia malayi CXXC zinc finger family protein 0.006 0.0602 0.106
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.1422 0.4814
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0318 0.1017
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0138 0.0162
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0136 0.0134
Schistosoma mansoni hypothetical protein 0.0007 0.0002 0.0003
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0096 0.011
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0188 0.0599
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0136 0.0433
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0147 0.0256
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0128 0.1366 0.1607
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0136 0.0158
Echinococcus multilocularis tumor protein p63 0.0367 0.4077 0.4076
Leishmania major glycosyl hydrolase-like protein 0.0013 0.0068 0.0212
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.0002 0.0003
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0007 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0011 0.0044 0.0075
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0068 0.0212
Loa Loa (eye worm) glutaminase 0.0267 0.2951 0.5215
Schistosoma mansoni importin beta-1 0.0029 0.025 0.0295
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0136 0.0134
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0318 0.1017
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0089 0.0087
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0138 0.0437
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0318 0.0371
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0396 0.2774
Brugia malayi Glycosyl hydrolases family 31 protein 0.0013 0.0068 0.0116
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0136 0.0237
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0138 0.0437
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0044 0.0075
Trichomonas vaginalis esterase, putative 0.0072 0.0731 0.2348
Schistosoma mansoni hypothetical protein 0.0016 0.0096 0.0113
Echinococcus granulosus pyruvate kinase 0.0068 0.0687 0.0806
Brugia malayi hypothetical protein 0.0019 0.0136 0.0237
Entamoeba histolytica serine/threonine protein kinase, putative 0.0281 0.3104 1
Brugia malayi MH2 domain containing protein 0.0116 0.1235 0.218
Entamoeba histolytica hypothetical protein 0.0019 0.0136 0.0439
Brugia malayi ecdysteroid receptor 0.0011 0.0044 0.0075
Trypanosoma cruzi polo-like protein kinase, putative 0.0281 0.3104 1
Entamoeba histolytica pyruvate kinase, putative 0.0092 0.0963 0.31
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0147 0.1586 0.1584
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0153 0.0296
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0136 0.0134
Loa Loa (eye worm) beta-lactamase 0.0072 0.0731 0.1288
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0136 0.0237
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0138 0.0437
Plasmodium vivax pyruvate kinase, putative 0.0132 0.1415 1
Schistosoma mansoni smad1 5 8 and 0.0008 0.0009 0.0011
Trypanosoma brucei glycosyl hydrolase-like protein 0.0013 0.0068 0.0212
Schistosoma mansoni Smad4 0.0008 0.0009 0.0011
Echinococcus granulosus pyruvate kinase 0.0068 0.0687 0.0806
Loa Loa (eye worm) hypothetical protein 0.0072 0.0731 0.1288
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0312 0.3452 0.6102
Entamoeba histolytica hypothetical protein 0.0147 0.1586 0.511
Echinococcus multilocularis pyruvate kinase 0.0132 0.1415 0.1413
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0356 0.1147
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0044 0.0052
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.004 0.0372 0.0654
Brugia malayi MH2 domain containing protein 0.0008 0.0009 0.0012
Echinococcus multilocularis dna polymerase eta 0.0019 0.0138 0.0136
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0043 0.0412 0.2913
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0136 0.0161
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0068 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0407 0.1306
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0002 0.0001
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0068 0.0212
Brugia malayi Pyruvate kinase, muscle isozyme 0.0132 0.1415 0.2499
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0044 0.005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0074 0.0232
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0138 0.0437
Onchocerca volvulus 0.0092 0.0958 0.308
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.0731 0.1428
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0136 0.0433
Toxoplasma gondii pyruvate kinase PyKII 0.0068 0.0687 0.4826
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0044 0.0075
Brugia malayi nuclear hormone receptor 0.0011 0.0044 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0044 0.0075
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0096 0.0166
Brugia malayi PXA domain containing protein 0.0019 0.0136 0.0237
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0043 0.0407 0.048
Schistosoma mansoni tar DNA-binding protein 0.0506 0.5656 0.6655
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0044 0.0042
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0138 0.0437
Leishmania major pyruvate kinase 0.0132 0.1415 0.4554
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0188 0.0599
Loa Loa (eye worm) pyruvate kinase 0.0028 0.0235 0.0411
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.0731 0.1288
Entamoeba histolytica hypothetical protein 0.0019 0.0136 0.0439
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0009 0.0011
Echinococcus multilocularis ubiquitin specific protease 41 0.0043 0.0407 0.0405
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0731 0.2348
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0138 0.046
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0138 0.0437
Onchocerca volvulus 0.0011 0.0044 0.0136
Mycobacterium ulcerans beta-lactamase 0.0072 0.0731 0.247
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0044 0.0075
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.025 0.08
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0044 0.005
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0318 0.1017
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0074 0.0232
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0044 0.0075
Schistosoma mansoni alpha-glucosidase 0.0136 0.1464 0.1723
Schistosoma mansoni aldehyde dehydrogenase 0.0132 0.1422 0.1673
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0044 0.0136
Loa Loa (eye worm) hypothetical protein 0.0019 0.0136 0.0237
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0281 0.3104 1
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.3104 1
Brugia malayi hypothetical protein 0.0147 0.1586 0.2802
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0068 0.0212
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0318 0.1017
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0147 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0044 0.0075
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0188 0.0599
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0044 0.005
Brugia malayi beta-lactamase family protein 0.0072 0.0731 0.1288
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0431 0.0507
Echinococcus multilocularis pyruvate kinase 0.0068 0.0687 0.0685
Loa Loa (eye worm) hypothetical protein 0.0072 0.0731 0.1288
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0153 0.0513
Schistosoma mansoni pyruvate kinase 0.0132 0.1415 0.1665
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0528 0.0621
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0136 0.0161
Plasmodium vivax importin-beta 2, putative 0.0029 0.025 0.077
Echinococcus granulosus cpg binding protein 0.0064 0.064 0.0751
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0318 0.1017
Mycobacterium ulcerans aldehyde dehydrogenase 0.0132 0.1422 0.4814
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0731 0.2348
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0044 0.0052
Echinococcus granulosus expressed protein 0.0372 0.4143 0.4874
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0731 0.2348
Echinococcus granulosus smad 0.0008 0.0009 0.0008
Echinococcus granulosus GPCR family 2 0.0016 0.0096 0.011
Echinococcus multilocularis pyruvate kinase 0.0132 0.1415 0.1413
Echinococcus granulosus microtubule associated protein 2 0.0757 0.8498 1
Echinococcus granulosus ubiquitin specific protease 41 0.0043 0.0407 0.0477
Schistosoma mansoni hypothetical protein 0.0016 0.0096 0.0113
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0074 0.0232
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0136 0.0161
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0138 0.0444
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0138 0.046
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0068 0.0212
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0013 0.0068 0.0212
Echinococcus granulosus importin subunit beta 1 0.0029 0.025 0.0292
Echinococcus granulosus pyruvate kinase 0.0068 0.0687 0.0806
Loa Loa (eye worm) hypothetical protein 0.0011 0.0044 0.0075
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0138 0.024
Loa Loa (eye worm) hypothetical protein 0.0132 0.1415 0.2499
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0731 0.4575
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0153 0.0487
Echinococcus multilocularis cpg binding protein 0.0064 0.064 0.0638
Echinococcus multilocularis pyruvate kinase 0.0104 0.11 0.1098
Brugia malayi pyruvate kinase, muscle isozyme 0.0028 0.0235 0.0411
Loa Loa (eye worm) hypothetical protein 0.0072 0.0731 0.1288
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0044 0.0075
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0131 0.0227
Echinococcus multilocularis dnaJ subfamily B 0.0448 0.5004 0.5003
Brugia malayi RNA, U transporter 1 0.0083 0.0861 0.1518
Loa Loa (eye worm) hypothetical protein 0.0072 0.0731 0.1288
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0044 0.0042
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0074 0.0232
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0007 0.0002 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0318 0.1017
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0131 0.0151
Schistosoma mansoni transcription factor LCR-F1 0.0147 0.1586 0.1867
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.007 0.0219
Loa Loa (eye worm) glutaminase 2 0.0267 0.2951 0.5215
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0044 0.0052
Onchocerca volvulus Pyruvate kinase homolog 0.0132 0.1415 0.4554
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0138 0.0437
Schistosoma mansoni hypothetical protein 0.0016 0.0096 0.0113
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0318 0.0316
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0044 0.0075
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0153 0.0267
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0096 0.011
Schistosoma mansoni tar DNA-binding protein 0.0506 0.5656 0.6655
Loa Loa (eye worm) hypothetical protein 0.0019 0.0136 0.0237
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0044 0.0042
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0143 0.1539 0.1811
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0074 0.0232
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0138 0.0437
Echinococcus multilocularis tar DNA binding protein 0.0506 0.5656 0.5655
Echinococcus multilocularis pyruvate kinase 0.0068 0.0687 0.0685
Giardia lamblia Pyruvate kinase 0.0068 0.0687 0.2208
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0138 0.0437
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0074 0.0232
Giardia lamblia DINP protein human, muc B family 0.0019 0.0138 0.0437
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0136 0.0237
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.0731 0.247
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0136 0.0134
Trichomonas vaginalis pyruvate kinase, putative 0.0132 0.1415 0.4554
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0044 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0074 0.0232
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0043 0.0412 0.041
Schistosoma mansoni aldehyde dehydrogenase 0.0007 0.0002 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.3104 1
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0007 0.0002 0.0007
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0153 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0044 0.005
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0043 0.0412 0.2889
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0153 0.0487
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0396 0.0463
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0318 0.1024
Onchocerca volvulus 0.0072 0.0731 0.2348
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0044 0.0052
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0147 0.0256
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0138 0.0437
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0009 0.0008
Brugia malayi serine/threonine-protein kinase plk-2 0.0281 0.3104 0.5487
Brugia malayi RNA recognition motif domain containing protein 0.0506 0.5656 1
Trichomonas vaginalis CAMK family protein kinase 0.0281 0.3104 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0044 0.0052
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0407 0.1306
Entamoeba histolytica hypothetical protein 0.0019 0.0136 0.0439
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0044 0.005
Trichomonas vaginalis pyruvate kinase, putative 0.0132 0.1415 0.4554
Entamoeba histolytica hypothetical protein 0.0147 0.1586 0.511
Echinococcus granulosus tar DNA binding protein 0.0506 0.5656 0.6654
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0074 0.0232
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0136 0.0237
Leishmania major hypothetical protein, conserved 0.0072 0.0731 0.2348
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0431 0.0758
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0407 0.1306
Loa Loa (eye worm) hypothetical protein 0.0029 0.025 0.0439
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0136 0.0161
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0396 0.1922
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0731 0.086
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0138 0.0437
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0281 0.3104 0.5487
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0044 0.0052
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0132 0.1422 0.4575
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0477 0.0839

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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