Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Toxoplasma gondii | deoxyhypusine synthase | 0.007 | 0.0699 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.045 | 0.9331 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0264 | 0.5103 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0264 | 0.5103 | 0.537 |
Leishmania major | NADPH-cytochrome p450 reductase-like protein | 0.0078 | 0.0874 | 0.0799 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.2277 | 0.2275 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0264 | 0.5103 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0124 | 0.1939 | 0.2272 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0134 | 0.2149 | 1 |
Loa Loa (eye worm) | deoxyhypusine synthase | 0.007 | 0.0699 | 0.0546 |
Brugia malayi | hypothetical protein | 0.0139 | 0.2277 | 0.212 |
Schistosoma mansoni | 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase | 0.0048 | 0.02 | 0.0392 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0124 | 0.1939 | 0.2218 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0264 | 0.5103 | 0.537 |
Trypanosoma cruzi | NADPH-dependent FMN/FAD containing oxidoreductase, putative | 0.0078 | 0.0874 | 0.0799 |
Brugia malayi | conserved hypotetical protein | 0.0124 | 0.1939 | 0.1774 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Schistosoma mansoni | thyroid hormone receptor | 0.0264 | 0.5103 | 1 |
Schistosoma mansoni | cytochrome P450 reductase | 0.0078 | 0.0874 | 0.1712 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0124 | 0.1939 | 0.2272 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0124 | 0.1939 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0264 | 0.5103 | 0.6406 |
Entamoeba histolytica | deoxyhypusine synthase, putative | 0.007 | 0.0699 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0264 | 0.5103 | 0.6406 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0264 | 0.5103 | 0.5003 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0134 | 0.2149 | 1 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0078 | 0.0874 | 0.0738 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0124 | 0.1939 | 0.3799 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0124 | 0.1939 | 0.3799 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.012 | 0.1844 | 0.8342 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0124 | 0.1939 | 0.2218 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.012 | 0.1844 | 0.8342 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0264 | 0.5103 | 0.537 |
Schistosoma mansoni | vesicular acetylcholine transporter | 0.0218 | 0.4065 | 0.7966 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0264 | 0.5103 | 0.5003 |
Loa Loa (eye worm) | glutathione reductase | 0.0053 | 0.031 | 0.0121 |
Trypanosoma cruzi | p450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.2277 | 0.2275 |
Leishmania major | p450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0264 | 0.5103 | 0.5003 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0264 | 0.5103 | 0.6406 |
Brugia malayi | hypothetical protein | 0.0139 | 0.2277 | 0.212 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.3329 | 0.3426 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0124 | 0.1939 | 0.2272 |
Brugia malayi | ecdysone receptor | 0.0124 | 0.1939 | 0.1774 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0264 | 0.5103 | 0.6406 |
Echinococcus multilocularis | NADPH dependent diflavin oxidoreductase 1 | 0.0078 | 0.0874 | 0.088 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Echinococcus multilocularis | nischarin | 0.0385 | 0.7853 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.012 | 0.1844 | 0.8342 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0264 | 0.5103 | 0.6406 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0264 | 0.5103 | 0.6406 |
Echinococcus multilocularis | NADPH cytochrome P450 reductase | 0.0078 | 0.0874 | 0.088 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0124 | 0.1939 | 0.2272 |
Trichomonas vaginalis | sulfite reductase, putative | 0.0078 | 0.0874 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0124 | 0.1939 | 0.2272 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0264 | 0.5103 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0264 | 0.5103 | 0.6531 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0124 | 0.1939 | 0.2272 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0264 | 0.5103 | 0.5003 |
Brugia malayi | nuclear hormone receptor | 0.0264 | 0.5103 | 0.5003 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0264 | 0.5103 | 0.5003 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0264 | 0.5103 | 0.537 |
Onchocerca volvulus | 0.0124 | 0.1939 | 0.2218 | |
Schistosoma mansoni | nuclear receptor | 0.0124 | 0.1939 | 0.3799 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0124 | 0.1939 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0363 | 0.7361 | 1 |
Mycobacterium ulcerans | formate dehydrogenase H FdhF | 0.0078 | 0.0874 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Brugia malayi | nuclear hormone receptor | 0.0124 | 0.1939 | 0.1774 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0264 | 0.5103 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0376 | 0.7652 | 0.8161 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0264 | 0.5103 | 0.6406 |
Leishmania major | deoxyhypusine synthase, putative | 0.007 | 0.0699 | 0.0551 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0053 | 0.031 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.2277 | 0.2275 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0264 | 0.5103 | 0.6406 |
Brugia malayi | glutathione reductase | 0.0053 | 0.031 | 0.0112 |
Brugia malayi | FAD binding domain containing protein | 0.0078 | 0.0874 | 0.0687 |
Schistosoma mansoni | zinc finger protein | 0.0124 | 0.1939 | 0.3799 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0124 | 0.1939 | 0.3799 |
Echinococcus granulosus | NADPH dependent diflavin oxidoreductase 1 | 0.0078 | 0.0874 | 0.088 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0134 | 0.2149 | 1 |
Echinococcus multilocularis | vesicular acetylcholine transporter | 0.0218 | 0.4065 | 0.505 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0139 | 0.2277 | 0.2275 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0124 | 0.1939 | 0.2272 |
Brugia malayi | tailless protein | 0.0124 | 0.1939 | 0.1774 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0264 | 0.5103 | 1 |
Trypanosoma brucei | NADPH-dependent diflavin oxidoreductase 1 | 0.0078 | 0.0874 | 0.0799 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0124 | 0.1939 | 0.2272 |
Plasmodium vivax | NADPH-cytochrome p450 reductase, putative | 0.0078 | 0.0874 | 1 |
Onchocerca volvulus | 0.0264 | 0.5103 | 0.6531 | |
Brugia malayi | hypothetical protein | 0.0376 | 0.7652 | 0.7604 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0053 | 0.031 | 0.0121 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0259 | 0.4988 | 0.6256 |
Schistosoma mansoni | coup transcription factor | 0.0264 | 0.5103 | 1 |
Brugia malayi | deoxyhypusine synthase | 0.007 | 0.0699 | 0.0509 |
Plasmodium vivax | flavodoxin domain containing protein | 0.0069 | 0.0673 | 0.6446 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Brugia malayi | nuclear receptor RXR | 0.0124 | 0.1939 | 0.1774 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0264 | 0.5103 | 0.5003 |
Chlamydia trachomatis | sulfite reductase | 0.0048 | 0.02 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0264 | 0.5103 | 0.5003 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0874 | 0.0738 |
Brugia malayi | flavodoxin family protein | 0.0078 | 0.0874 | 0.0687 |
Brugia malayi | ecdysteroid receptor | 0.0264 | 0.5103 | 0.5003 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0139 | 0.2277 | 0.4463 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0124 | 0.1939 | 0.1774 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0363 | 0.7361 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0264 | 0.5103 | 0.5003 |
Brugia malayi | hypothetical protein | 0.0124 | 0.1939 | 0.1774 |
Brugia malayi | hypothetical protein | 0.0259 | 0.4988 | 0.4886 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0139 | 0.2277 | 0.4463 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0264 | 0.5103 | 1 |
Echinococcus granulosus | NADPH cytochrome P450 reductase | 0.0078 | 0.0874 | 0.088 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.012 | 0.1844 | 0.8342 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0264 | 0.5103 | 0.537 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0124 | 0.1939 | 0.2272 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0124 | 0.1939 | 0.1774 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0264 | 0.5103 | 0.5003 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.2277 | 0.2275 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0053 | 0.0311 | 0.0113 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0264 | 0.5103 | 0.6406 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0124 | 0.1939 | 0.2272 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0134 | 0.2149 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0264 | 0.5103 | 0.6406 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.012 | 0.1844 | 0.8342 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0259 | 0.4988 | 0.6256 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0124 | 0.1939 | 0.1904 |
Mycobacterium tuberculosis | Probable reductase | 0.012 | 0.1844 | 0.8342 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0139 | 0.2277 | 0.212 |
Trichomonas vaginalis | deoxyhypusine synthase, putative | 0.007 | 0.0699 | 0.1271 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0124 | 0.1939 | 0.1774 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0139 | 0.2277 | 0.212 |
Brugia malayi | Thioredoxin reductase | 0.0053 | 0.031 | 0.0112 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0264 | 0.5103 | 0.6406 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Schistosoma mansoni | nuclear hormone receptor | 0.0124 | 0.1939 | 0.3799 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0363 | 0.7361 | 1 |
Brugia malayi | vesicular acetylcholine transporter unc-17 | 0.0218 | 0.4065 | 0.3944 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0264 | 0.5103 | 0.5003 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0124 | 0.1939 | 0.2272 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0124 | 0.1939 | 0.1774 |
Brugia malayi | nuclear receptor NHR-88 | 0.0124 | 0.1939 | 0.1774 |
Plasmodium vivax | deoxyhypusine synthase, putative | 0.007 | 0.0699 | 0.6898 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0264 | 0.5103 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0264 | 0.5103 | 0.6406 |
Echinococcus granulosus | nischarin | 0.0385 | 0.7853 | 1 |
Leishmania major | cytochrome P450 reductase, putative | 0.0069 | 0.0673 | 0.0515 |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.7361 | 0.7843 |
Echinococcus granulosus | vesicular acetylcholine transporter | 0.0218 | 0.4065 | 0.505 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.4988 | 0.5244 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0264 | 0.5103 | 0.6406 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0139 | 0.2277 | 0.2714 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0264 | 0.5103 | 0.6406 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0053 | 0.031 | 0.0144 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0264 | 0.5103 | 0.5003 |
Brugia malayi | nuclear receptor RXR | 0.0139 | 0.2277 | 0.212 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0264 | 0.5103 | 0.6531 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0264 | 0.5103 | 0.537 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0264 | 0.5103 | 0.6406 |
Echinococcus multilocularis | deoxyhypusine synthase | 0.007 | 0.0699 | 0.0652 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0264 | 0.5103 | 0.5003 |
Plasmodium falciparum | nitric oxide synthase, putative | 0.0078 | 0.0874 | 1 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0363 | 0.7361 | 0.7307 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0264 | 0.5103 | 0.5003 |
Onchocerca volvulus | 0.0124 | 0.1939 | 0.2218 | |
Brugia malayi | nuclear receptor NHR-88 | 0.0264 | 0.5103 | 0.5003 |
Schistosoma mansoni | nuclear hormone receptor | 0.0264 | 0.5103 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.2277 | 0.2275 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Echinococcus granulosus | deoxyhypusine synthase | 0.007 | 0.0699 | 0.0652 |
Brugia malayi | steroid hormone receptor | 0.0264 | 0.5103 | 0.5003 |
Brugia malayi | nuclear receptor NHR-67 | 0.0124 | 0.1939 | 0.1774 |
Schistosoma mansoni | survival motor neuron protein | 0.0053 | 0.0311 | 0.061 |
Schistosoma mansoni | thyroid hormone receptor | 0.0264 | 0.5103 | 1 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0124 | 0.1939 | 0.1774 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0264 | 0.5103 | 0.6406 |
Giardia lamblia | Deoxyhypusine synthase, putative | 0.007 | 0.0699 | 1 |
Trypanosoma cruzi | deoxyhypusine synthase, putative | 0.007 | 0.0699 | 0.0551 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.1939 | 0.1904 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0264 | 0.5103 | 0.6406 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.5103 | 0.537 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0264 | 0.5103 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0124 | 0.1939 | 0.2272 |
Entamoeba histolytica | deoxyhypusine synthase, putative | 0.007 | 0.0699 | 0.5 |
Loa Loa (eye worm) | vesicular acetylcholine transporter unc-17 | 0.0218 | 0.4065 | 0.4233 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0264 | 0.5103 | 0.5003 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0264 | 0.5103 | 0.6531 |
Schistosoma mansoni | nuclear receptor | 0.0124 | 0.1939 | 0.3799 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0264 | 0.5103 | 0.537 |
Schistosoma mansoni | deoxyhypusine synthase | 0.007 | 0.0699 | 0.137 |
Brugia malayi | hypothetical protein | 0.0124 | 0.1939 | 0.1774 |
Trypanosoma brucei | NADPH-cytochrome p450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0264 | 0.5103 | 0.537 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0139 | 0.2277 | 0.2714 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0078 | 0.0874 | 0.0799 |
Loa Loa (eye worm) | DR-78 | 0.0124 | 0.1939 | 0.1904 |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.0311 | 0.061 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0264 | 0.5103 | 0.5003 |
Brugia malayi | Dopamine receptor protein 1 | 0.045 | 0.9331 | 0.9317 |
Plasmodium falciparum | deoxyhypusine synthase | 0.007 | 0.0699 | 0.6898 |
Schistosoma mansoni | nuclear hormone receptor | 0.0124 | 0.1939 | 0.3799 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0264 | 0.5103 | 1 |
Trypanosoma brucei | deoxyhypusine synthase | 0.007 | 0.0699 | 0.0551 |
Onchocerca volvulus | Vesicular acetylcholine transporter homolog | 0.0218 | 0.4065 | 0.5117 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0124 | 0.1939 | 0.1774 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0264 | 0.5103 | 0.6406 |
Onchocerca volvulus | Nischarin homolog | 0.0376 | 0.7648 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0264 | 0.5103 | 0.5003 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 43.5 % | Percentage inhibition of compound against morphine at 10 e-7 M in guinea pig ileum tissue | ChEMBL. | 2754695 |
Inhibition (functional) | = 91.5 % | Ability to display a naloxone-reversible inhibition of electrically induced contractions in GPI in the presence of 1.0 microM bestatin at concentration 10 e-6 M | ChEMBL. | 2754695 |
Ke (functional) | = 4.2 nM | Inhibitory activity in guinea pig ileum tissue in the absence and presence of 10 nM naloxone | ChEMBL. | 2754695 |
Relative potency (functional) | = 21.2 | Ability to display a naloxone-reversible inhibition of electrically induced contractions in GPI by Morphine at 0.1 microM | ChEMBL. | 2754695 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.