Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | mitochondrial DNA polymerase beta | 0.0297 | 0.3546 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0323 | 0.0443 |
Onchocerca volvulus | 0.007 | 0.0695 | 0.2259 | |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0109 | 0.015 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0297 | 0.3546 | 1 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0595 | 0.7298 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0109 | 0.0386 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0007 | 0.0022 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0015 | 0.0007 | 0.0007 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0755 | 0.9312 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0599 | 0.0643 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0228 | 0.268 | 0.9122 |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.0595 | 0.7298 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0033 | 0.0227 | 0.0227 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0599 | 0.0643 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0595 | 0.7298 | 1 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0015 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0035 | 0.012 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.014 | 0.1581 | 0.446 |
Onchocerca volvulus | 0.004 | 0.0323 | 0.105 | |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.0058 | 0.5 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0078 | 0.0793 | 0.0793 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0267 | 0.0943 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.0058 | 0.0163 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.014 | 0.1581 | 0.446 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.004 | 0.0323 | 0.0443 |
Mycobacterium tuberculosis | Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) | 0.004 | 0.0323 | 0.0443 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0066 | 0.0643 | 0.069 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0297 | 0.3546 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.0033 | 0.0227 | 0.0303 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0267 | 0.0366 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0267 | 0.0909 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0035 | 0.012 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0058 | 0.0163 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0015 | 0.0007 | 0.0007 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0267 | 0.0366 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0058 | 0.0163 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0109 | 0.015 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.004 | 0.0323 | 0.0443 |
Brugia malayi | Pre-SET motif family protein | 0.0228 | 0.268 | 0.9466 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.0599 | 0.2037 |
Leishmania major | stearic acid desaturase, putative | 0.007 | 0.0695 | 0.1959 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0033 | 0.0227 | 0.0311 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0078 | 0.0793 | 0.2699 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.0058 | 0.0163 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0267 | 0.0289 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0109 | 0.0386 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0741 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.0058 | 0.0079 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.014 | 0.1581 | 0.446 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0058 | 0.0163 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0227 | 0.0773 |
Echinococcus granulosus | lamin | 0.0027 | 0.0161 | 0.0172 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.0599 | 0.0599 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0066 | 0.0643 | 0.069 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0007 | 0.0022 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0066 | 0.0643 | 0.1812 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0161 | 0.0172 |
Echinococcus multilocularis | serotonin transporter | 0.0015 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0007 | 0.0022 |
Schistosoma mansoni | single-minded | 0.0048 | 0.0417 | 0.0448 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0267 | 0.0909 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0161 | 0.0547 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0058 | 0.0062 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0323 | 0.0443 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0595 | 0.7298 | 1 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.004 | 0.0323 | 0.11 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0227 | 0.0244 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0066 | 0.0643 | 0.2187 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0007 | 0.0022 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0038 | 0.0295 | 0.0316 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0058 | 0.0163 |
Entamoeba histolytica | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.004 | 0.0323 | 0.3879 |
Loa Loa (eye worm) | hypothetical protein | 0.0248 | 0.2938 | 1 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0595 | 0.7298 | 1 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.0058 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0154 | 0.0525 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0595 | 0.7298 | 1 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.0035 | 0.0039 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0267 | 0.0289 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0267 | 0.0366 |
Leishmania major | fatty-acid desaturase, putative | 0.007 | 0.0695 | 0.1959 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0015 | 0.0007 | 0.0023 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0267 | 0.0366 |
Echinococcus multilocularis | serotonin receptor | 0.0248 | 0.2938 | 0.2938 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.004 | 0.0323 | 0.0443 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.004 | 0.0323 | 0.0443 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0015 | 0.0007 | 0.0022 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.1909 | 0.205 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0267 | 0.0943 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0599 | 0.0643 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0015 | 0.0007 | 0.0007 |
Toxoplasma gondii | 3-ketoacyl-(acyl-carrier-protein) reductase | 0.004 | 0.0323 | 0.0443 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0341 | 0.0961 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0161 | 0.0567 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0023 | 0.0032 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0035 | 0.0261 | 0.0261 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0015 | 0.0007 | 0.0007 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0015 | 0.0007 | 0.0007 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.0212 | 0.0228 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0017 | 0.0035 | 0.0048 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0058 | 0.0205 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0015 | 0.0007 | 0.0007 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0125 | 0.0352 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0148 | 0.1676 | 0.5703 |
Echinococcus multilocularis | serotonin receptor | 0.0248 | 0.2938 | 0.2938 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0015 | 0.0007 | 0.0007 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0066 | 0.0643 | 0.1812 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0058 | 0.0163 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.004 | 0.0323 | 0.1141 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0015 | 0.0007 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0058 | 0.0163 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0066 | 0.0643 | 0.0643 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0015 | 0.0007 | 0.0007 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0051 | 0.0456 | 0.1285 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0125 | 0.0352 |
Brugia malayi | MH2 domain containing protein | 0.0121 | 0.134 | 0.4732 |
Onchocerca volvulus | 0.0015 | 0.0007 | 0.0021 | |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0109 | 0.0372 |
Onchocerca volvulus | 0.007 | 0.0695 | 0.2259 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0599 | 0.0643 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0015 | 0.0007 | 0.0007 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0042 | 0.0341 | 0.0961 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0015 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0267 | 0.0909 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.004 | 0.0323 | 0.0443 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0058 | 0.0163 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0121 | 0.134 | 0.4561 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0267 | 0.0366 |
Mycobacterium ulcerans | 20-beta-hydroxysteroid dehydrogenase FabG3 | 0.004 | 0.0323 | 0.0443 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0267 | 0.0753 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0755 | 0.9312 | 0.9312 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0109 | 0.015 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0058 | 0.0163 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0267 | 0.0366 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0058 | 0.0062 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0058 | 0.0079 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.1909 | 0.205 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0323 | 0.0443 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0015 | 0.0007 | 0.0023 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.004 | 0.0323 | 0.0911 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0323 | 0.0443 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0058 | 0.0062 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1832 | 0.6234 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0058 | 0.0197 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.0058 | 0.0062 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0023 | 0.0032 |
Onchocerca volvulus | 0.004 | 0.0323 | 0.105 | |
Onchocerca volvulus | 0.0015 | 0.0007 | 0.0021 | |
Echinococcus multilocularis | musashi | 0.0027 | 0.0161 | 0.0161 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.004 | 0.0323 | 0.0443 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0058 | 0.0163 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.004 | 0.0323 | 0.0443 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.004 | 0.0323 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0035 | 0.012 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0109 | 0.0386 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.004 | 0.0323 | 0.0443 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0015 | 0.0007 | 0.0022 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] reductase, putative | 0.004 | 0.0323 | 0.0434 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0042 | 0.0341 | 0.0961 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.0058 | 0.0062 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0033 | 0.0227 | 0.0244 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.0599 | 0.0643 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0227 | 0.0244 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.004 | 0.0323 | 0.0443 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0109 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0793 | 0.2699 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0267 | 0.0753 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0109 | 0.075 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0267 | 0.0287 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0109 | 0.0308 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0267 | 0.0943 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0058 | 0.0163 |
Trypanosoma brucei | oxidoreductase-like protein | 0.004 | 0.0323 | 0.0911 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0156 | 0.1781 | 0.244 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0323 | 0.0443 |
Trichomonas vaginalis | hypothetical protein | 0.0595 | 0.7298 | 1 |
Onchocerca volvulus | 0.0023 | 0.0109 | 0.0355 | |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0074 | 0.0741 | 0.0741 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.004 | 0.0323 | 0.0443 |
Leishmania major | oxidoreductase-like protein | 0.004 | 0.0323 | 0.0911 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0048 | 0.0417 | 0.0448 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0015 | 0.0007 | 0.0007 |
Plasmodium vivax | stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative | 0.0055 | 0.0511 | 0.0692 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0109 | 0.015 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0109 | 0.0308 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.0599 | 0.2037 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.0599 | 0.2114 |
Schistosoma mansoni | dihydropteridine reductase | 0.004 | 0.0323 | 0.0347 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0109 | 0.015 |
Trichomonas vaginalis | set domain proteins, putative | 0.0259 | 0.3076 | 0.4168 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.0058 | 0.0163 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0125 | 0.0171 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0161 | 0.0547 |
Onchocerca volvulus | 0.0259 | 0.3076 | 1 | |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.004 | 0.0323 | 0.0443 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0125 | 0.0352 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0599 | 0.0643 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0015 | 0.0007 | 0.0009 |
Onchocerca volvulus | 0.0027 | 0.0161 | 0.0522 | |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.004 | 0.0323 | 0.0347 |
Onchocerca volvulus | 0.0033 | 0.0227 | 0.0739 | |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0267 | 0.0753 |
Mycobacterium ulcerans | oxidoreductase | 0.004 | 0.0323 | 0.0443 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.004 | 0.0323 | 0.0347 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0007 | 0.0022 |
Chlamydia trachomatis | oxoacy-ACP reductase | 0.004 | 0.0323 | 0.0434 |
Echinococcus granulosus | geminin | 0.0166 | 0.1909 | 0.205 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0741 | 0.0796 |
Echinococcus granulosus | serotonin transporter | 0.0015 | 0.0007 | 0.0007 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0125 | 0.0162 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0015 | 0.0007 | 0.0007 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0161 | 0.0172 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0078 | 0.0793 | 0.0852 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0109 | 0.075 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0109 | 0.015 |
Brugia malayi | hypoxia-induced factor 1 | 0.0148 | 0.1676 | 0.5918 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0078 | 0.0793 | 0.0852 |
Mycobacterium tuberculosis | Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) | 0.004 | 0.0323 | 0.0443 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0058 | 0.0163 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0323 | 0.0443 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.0599 | 0.2037 |
Loa Loa (eye worm) | oxidoreductase | 0.004 | 0.0323 | 0.11 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0267 | 0.0287 |
Mycobacterium leprae | 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI | 0.004 | 0.0323 | 0.0298 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0267 | 0.0366 |
Onchocerca volvulus | 0.0027 | 0.0161 | 0.0522 | |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0793 | 0.2699 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0015 | 0.0007 | 0.0007 |
Leishmania major | pteridine reductase 1 | 0.004 | 0.0323 | 0.0911 |
Onchocerca volvulus | 0.0036 | 0.0267 | 0.0868 | |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0248 | 0.2938 | 0.3155 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0066 | 0.0643 | 0.2269 |
Trypanosoma brucei | pteridine reductase 1 | 0.004 | 0.0323 | 0.0911 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0074 | 0.0741 | 0.0796 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0038 | 0.0295 | 0.0295 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0066 | 0.0643 | 0.1812 |
Leishmania major | 3-oxoacyl-ACP reductase, putative | 0.004 | 0.0323 | 0.0911 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0035 | 0.012 |
Brugia malayi | bHLH-PAS transcription factor | 0.0035 | 0.0261 | 0.0922 |
Toxoplasma gondii | short chain dehydrogenase family protein, putative | 0.004 | 0.0323 | 0.0443 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0229 | 0.2695 | 0.3693 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.0035 | 0.0039 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0023 | 0.0032 |
Mycobacterium leprae | POSSIBLE OXIDOREDUCTASE | 0.004 | 0.0323 | 0.0298 |
Plasmodium falciparum | 3-oxoacyl-[acyl-carrier-protein] reductase | 0.004 | 0.0323 | 0.0434 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0125 | 0.0352 |
Onchocerca volvulus | 0.0015 | 0.0007 | 0.0021 | |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0066 | 0.0643 | 0.8553 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0109 | 0.015 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0033 | 0.0227 | 0.0244 |
Brugia malayi | hypothetical protein | 0.0074 | 0.0741 | 0.2619 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.0058 | 0.0062 |
Schistosoma mansoni | lamin | 0.0027 | 0.0161 | 0.0172 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0267 | 0.0366 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.0035 | 0.0039 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0125 | 0.0162 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0055 | 0.0511 | 0.1442 |
Schistosoma mansoni | lamin | 0.0027 | 0.0161 | 0.0172 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0267 | 0.0289 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.004 | 0.0323 | 0.0443 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.004 | 0.0323 | 0.0323 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0015 | 0.0007 | 0.0009 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0595 | 0.7298 | 1 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0595 | 0.7298 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0023 | 0.0032 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0267 | 0.0366 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0267 | 0.0289 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.0058 | 0.0163 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0058 | 0.0163 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.004 | 0.0323 | 0.0443 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0267 | 0.0289 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0267 | 0.022 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0058 | 0.0163 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0267 | 0.0366 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0015 | 0.0007 | 0.0023 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0267 | 0.0366 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0015 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0248 | 0.2938 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0125 | 0.0424 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.0058 | 0.0058 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0741 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0323 | 0.0443 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0161 | 0.0161 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.004 | 0.0323 | 0.0443 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.004 | 0.0323 | 0.0443 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0161 | 0.0161 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0267 | 0.0289 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0015 | 0.0001 | 0.0003 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0015 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.004 | 0.0323 | 0.11 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.004 | 0.0323 | 0.0443 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0125 | 0.044 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.0058 | 0.0163 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0267 | 0.0366 |
Brugia malayi | follicle stimulating hormone receptor | 0.024 | 0.2832 | 1 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0058 | 0.0058 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.004 | 0.0323 | 0.0443 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0161 | 0.0567 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0109 | 0.015 |
Toxoplasma gondii | hypothetical protein | 0.0048 | 0.0418 | 0.0573 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0121 | 0.134 | 0.4561 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0109 | 0.015 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.0058 | 0.0163 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0058 | 0.0205 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0267 | 0.0366 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0015 | 0.0055 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0125 | 0.0162 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0267 | 0.0267 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase | 0.004 | 0.0323 | 0.0911 |
Mycobacterium ulcerans | putative regulatory protein | 0.0035 | 0.0261 | 0.0358 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0741 | 1 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0341 | 0.0961 |
Brugia malayi | hypothetical protein | 0.0015 | 0.0007 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0007 | 0.0022 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0055 | 0.0511 | 0.1442 |
Onchocerca volvulus | 0.0015 | 0.0007 | 0.0021 | |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0078 | 0.0793 | 0.0852 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0161 | 0.0547 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.004 | 0.0323 | 0.0911 |
Brugia malayi | hypothetical protein | 0.016 | 0.1832 | 0.6469 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0323 | 0.0443 |
Echinococcus granulosus | single minded 2 | 0.0035 | 0.0261 | 0.028 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0267 | 0.0357 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0035 | 0.0048 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0015 | 0.0007 | 0.0007 |
Onchocerca volvulus | 0.0036 | 0.0267 | 0.0868 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0058 | 0.0163 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0248 | 0.2938 | 0.3155 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0323 | 0.11 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0058 | 0.0079 |
Toxoplasma gondii | hypothetical protein | 0.0015 | 0.0007 | 0.0009 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.0058 | 0.0058 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0078 | 0.0793 | 0.2801 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0741 | 1 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0015 | 0.0007 | 0.0009 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.024 | 0.2832 | 0.9637 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0267 | 0.0366 |
Loa Loa (eye worm) | acyl-CoA desaturase | 0.0055 | 0.0511 | 0.174 |
Onchocerca volvulus | 0.0035 | 0.0261 | 0.0849 | |
Onchocerca volvulus | 0.0036 | 0.0267 | 0.0868 | |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0033 | 0.0227 | 0.0227 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0109 | 0.0308 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0015 | 0.0007 | 0.0007 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0267 | 0.0753 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0015 | 0.0007 | 0.0023 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0297 | 0.3546 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0074 | 0.0741 | 0.0796 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0007 | 0.0022 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0323 | 0.0443 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0323 | 0.0443 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.0599 | 0.2114 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0267 | 0.0909 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.004 | 0.0323 | 0.0443 |
Echinococcus multilocularis | geminin | 0.0166 | 0.1909 | 0.1909 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.0058 | 0.0079 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.004 | 0.0323 | 0.0443 |
Brugia malayi | RNA binding protein | 0.0062 | 0.0599 | 0.2114 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0267 | 0.0366 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0058 | 0.0163 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0109 | 0.0372 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0058 | 0.0163 |
Plasmodium falciparum | stearoyl-CoA desaturase | 0.0055 | 0.0511 | 0.0692 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0267 | 0.0909 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0161 | 0.0172 |
Toxoplasma gondii | hypothetical protein | 0.0015 | 0.0007 | 0.0009 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0078 | 0.0793 | 0.0852 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0109 | 0.0372 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0267 | 0.0909 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0109 | 0.015 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.004 | 0.0323 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0267 | 0.0909 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0267 | 0.0909 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0267 | 0.0287 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0015 | 0.0007 | 0.0022 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.004 | 0.0323 | 0.0911 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0323 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0035 | 0.012 |
Loa Loa (eye worm) | serotonin transporter b | 0.0015 | 0.0007 | 0.0022 |
Brugia malayi | PAS domain containing protein | 0.0048 | 0.0417 | 0.1473 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0267 | 0.022 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.004 | 0.0323 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0007 | 0.0022 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.004 | 0.0323 | 0.0911 |
Brugia malayi | acyl-CoA desaturase | 0.0055 | 0.0511 | 0.1805 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0267 | 0.0943 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0058 | 0.0163 |
Brugia malayi | Pre-SET motif family protein | 0.0033 | 0.0227 | 0.0802 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.004 | 0.0323 | 0.0443 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0001 | 0.0003 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.007 | 0.0695 | 0.1959 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.004 | 0.0323 | 0.0911 |
Trypanosoma brucei | fatty acid desaturase, putative | 0.007 | 0.0695 | 0.1959 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0755 | 0.9312 | 1 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.004 | 0.0323 | 0.0443 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0066 | 0.0643 | 0.1812 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0267 | 0.0366 |
Mycobacterium ulcerans | hypothetical protein | 0.0156 | 0.1781 | 0.244 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.004 | 0.0323 | 0.0443 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.004 | 0.0323 | 0.0443 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0227 | 0.0244 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0078 | 0.0793 | 0.0793 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.