Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.042 | 0.042 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0199 | 0.042 | 0.042 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0199 | 0.042 | 0.5 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0199 | 0.042 | 0.5 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0199 | 0.042 | 0.5 |
Onchocerca volvulus | 0.0199 | 0.042 | 0.5 | |
Trypanosoma brucei | aminopeptidase, putative | 0.0199 | 0.042 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0199 | 0.042 | 0.042 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.015 | 0.0289 | 0.0289 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.015 | 0.0289 | 0.0637 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0199 | 0.042 | 0.5 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0199 | 0.042 | 0.5 |
Toxoplasma gondii | aminopeptidase N protein | 0.0199 | 0.042 | 0.5 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0199 | 0.042 | 0.042 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.042 | 0.042 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0199 | 0.042 | 0.042 |
Brugia malayi | Peptidase family M1 containing protein | 0.0199 | 0.042 | 0.0926 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0199 | 0.042 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0199 | 0.042 | 0.042 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0199 | 0.042 | 0.5 |
Brugia malayi | TATA binding protein associated factor | 0.0199 | 0.042 | 0.0926 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0199 | 0.042 | 0.042 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0199 | 0.042 | 0.042 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0199 | 0.042 | 0.042 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0199 | 0.042 | 0.042 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0199 | 0.042 | 0.042 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0164 | 0.0326 | 0.0326 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.042 | 0.042 |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0199 | 0.042 | 0.5 |
Brugia malayi | hypothetical protein | 0.0199 | 0.042 | 0.0926 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0199 | 0.042 | 0.5 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.3742 | 1 | 1 |
Echinococcus multilocularis | aminopeptidase N | 0.0199 | 0.042 | 0.042 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0199 | 0.042 | 0.042 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0199 | 0.042 | 0.5 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0199 | 0.042 | 0.5 |
Entamoeba histolytica | aminopeptidase, putative | 0.0199 | 0.042 | 0.5 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0199 | 0.042 | 0.5 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0199 | 0.042 | 0.5 |
Brugia malayi | hypothetical protein | 0.0199 | 0.042 | 0.0926 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0199 | 0.042 | 0.5 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.3742 | 1 | 1 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0199 | 0.042 | 0.5 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0199 | 0.042 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0199 | 0.042 | 0.042 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0199 | 0.042 | 0.042 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0164 | 0.0326 | 0.0326 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0199 | 0.042 | 0.042 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0199 | 0.042 | 0.042 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.015 | 0.0289 | 0.0289 |
Onchocerca volvulus | 0.0199 | 0.042 | 0.5 | |
Loa Loa (eye worm) | aminopeptidase N | 0.0199 | 0.042 | 0.042 |
Brugia malayi | Peptidase family M1 containing protein | 0.0199 | 0.042 | 0.0926 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0199 | 0.042 | 0.5 |
Onchocerca volvulus | 0.0199 | 0.042 | 0.5 | |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0199 | 0.042 | 0.5 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0199 | 0.042 | 0.5 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.3742 | 1 | 1 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0199 | 0.042 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0199 | 0.042 | 0.0926 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0199 | 0.042 | 0.5 |
Echinococcus granulosus | aminopeptidase N | 0.0199 | 0.042 | 0.042 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0199 | 0.042 | 0.5 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.015 | 0.0289 | 0.0289 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0199 | 0.042 | 0.5 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0199 | 0.042 | 0.042 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.0235 | 0.0235 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0199 | 0.042 | 0.042 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0199 | 0.042 | 0.042 |
Brugia malayi | hypothetical protein | 0.172 | 0.4534 | 1 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0199 | 0.042 | 1 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0199 | 0.042 | 1 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0199 | 0.042 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.