Detailed information for compound 701167

Basic information

Technical information
  • TDR Targets ID: 701167
  • Name: N-(2,4-difluorophenyl)-2-[[1-(3-dimethylamino propyl)-2-oxo-6,7-dihydro-5H-cyclopenta[e]pyr imidin-4-yl]sulfanyl]acetamide
  • MW: 422.492 | Formula: C20H24F2N4O2S
  • H donors: 1 H acceptors: 2 LogP: 2.57 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(CCCn1c(=O)nc(c2c1CCC2)SCC(=O)Nc1ccc(cc1F)F)C
  • InChi: 1S/C20H24F2N4O2S/c1-25(2)9-4-10-26-17-6-3-5-14(17)19(24-20(26)28)29-12-18(27)23-16-8-7-13(21)11-15(16)22/h7-8,11H,3-6,9-10,12H2,1-2H3,(H,23,27)
  • InChiKey: GHVVDZKUXQFFSE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2,4-difluorophenyl)-2-[[1-(3-dimethylaminopropyl)-2-oxo-6,7-dihydro-5H-cyclopenta[e]pyrimidin-4-yl]thio]acetamide
  • N-(2,4-difluorophenyl)-2-[[1-(3-dimethylaminopropyl)-2-keto-6,7-dihydro-5H-cyclopenta[e]pyrimidin-4-yl]thio]acetamide
  • N-(2,4-difluorophenyl)-2-[[1-(3-dimethylaminopropyl)-2-oxo-6,7-dihydro-5H-cyclopenta[e]pyrimidin-4-yl]sulfanyl]ethanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0072 0.0432 0.1026
Loa Loa (eye worm) hypothetical protein 0.0031 0.014 0.0331
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0061 0.0146
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.0432 0.1207
Plasmodium vivax proline--tRNA ligase, putative 0.0116 0.0745 0.0735
Echinococcus granulosus short transient receptor potential channel 6 0.0125 0.0811 0.1359
Giardia lamblia Hexose transporter 0.0047 0.0248 0.1158
Echinococcus granulosus solute carrier family 22 0.0047 0.0248 0.0412
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0017 0.0036 0.0376
Schistosoma mansoni thyroid hormone receptor 0.0029 0.0123 0.0202
Entamoeba histolytica hypothetical protein 0.0074 0.0445 0.213
Loa Loa (eye worm) hypothetical protein 0.0029 0.0123 0.0293
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.0432 0.1207
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0029 0.0043
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0089 0.0554 0.1557
Mycobacterium leprae Probable lipase LipE 0.0072 0.0432 0.4306
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0089 0.0554 0.1557
Echinococcus granulosus transient receptor potential gamma protein 0.0189 0.127 0.2131
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0013 0.0016
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0013 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0029 0.0123 0.0293
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0116 0.0745 0.9526
Mycobacterium ulcerans sugar transporter 0.0047 0.0248 0.2494
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0029 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0248 0.0705
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0116 0.0745 1
Giardia lamblia Sugar-proton symporter 0.0047 0.0248 0.1158
Loa Loa (eye worm) hypothetical protein 0.0189 0.127 0.3014
Chlamydia trachomatis neutral amino acid transporter 0.0221 0.1503 0.4277
Loa Loa (eye worm) hypothetical protein 0.0047 0.0248 0.0589
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0011 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0032 0.0329
Schistosoma mansoni aldehyde dehydrogenase 0.0121 0.0782 0.1309
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0011 0.0045
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0221 0.1503 0.2522
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0011 0.0045
Brugia malayi Thioredoxin reductase 0.0039 0.0195 0.0535
Brugia malayi hypothetical protein 0.0242 0.1648 0.47
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0061 0.0098
Trypanosoma cruzi hexose transporter 0.0103 0.0651 0.8724
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0642 0.1074
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0099 0.0626 0.1762
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Onchocerca volvulus 0.0047 0.0248 0.0688
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0099 0.0261
Echinococcus multilocularis ubiquitin specific protease 41 0.0076 0.046 0.0768
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0013 0.0014
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0074 0.0445 0.5922
Loa Loa (eye worm) hypothetical protein 0.0047 0.0248 0.0589
Echinococcus granulosus solute carrier family 22 0.0047 0.0248 0.0412
Plasmodium vivax glycine--tRNA ligase, putative 0.0019 0.0048 0.0036
Schistosoma mansoni alpha glucosidase 0.0035 0.0166 0.0274
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0059
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0432 0.4306
Schistosoma mansoni jumonji domain containing protein 0.006 0.0345 0.0575
Onchocerca volvulus 0.0047 0.0248 0.0688
Brugia malayi Major Facilitator Superfamily protein 0.0047 0.0248 0.0688
Echinococcus granulosus thioredoxin glutathione reductase 0.004 0.0198 0.0328
Plasmodium vivax thioredoxin reductase, putative 0.0039 0.0195 0.0184
Toxoplasma gondii sugar transporter ST3 0.0047 0.0248 0.0358
Plasmodium vivax ataxin-2 like protein, putative 0.0047 0.0254 0.0243
Echinococcus multilocularis neuropeptide s receptor 0.0474 0.3316 0.5573
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0013 0.0031
Onchocerca volvulus 0.0047 0.0248 0.0688
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0013 0.0016
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0432 0.1244
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0041 0.0211 0.2749
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0121 0.0782 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0029 0.0123 0.0202
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0011 0.0045
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0053 0.0084
Brugia malayi Cam kinase protein 1 0.0101 0.0642 0.1816
Onchocerca volvulus 0.0047 0.0248 0.0688
Echinococcus granulosus excitatory amino acid transporter 3 0.05 0.3498 0.5879
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0331 0.2291 0.3848
Echinococcus granulosus Threonyl tRNA synthetase C 0.0019 0.0048 0.0075
Echinococcus granulosus synaptic vesicle 2 protein 0.0047 0.0248 0.0412
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0029 0.0123 0.0293
Onchocerca volvulus 0.0047 0.0248 0.0688
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0099 0.0626 0.6388
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0331 0.2291 0.3848
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0019 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0006
Trichomonas vaginalis glucose transporter, putative 0.0047 0.0248 0.0705
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0029 0.0123 0.0202
Echinococcus granulosus FTZ F1 alpha 0.0029 0.0123 0.0202
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.105 0.1761
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0029 0.0069
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.001 0.0006
Echinococcus granulosus lysyl tRNA synthetase 0.0074 0.0445 0.0742
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0076 0.046 0.0768
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0123 0.0331
Onchocerca volvulus Bile acid receptor homolog 0.0029 0.0123 0.0331
Mycobacterium ulcerans aldehyde dehydrogenase 0.0121 0.0782 0.8112
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0029 0.0069
Trypanosoma brucei glucose transporter, putative 0.0103 0.0651 0.8724
Schistosoma mansoni nuclear receptor 0.0014 0.0013 0.0016
Leishmania major importin beta-1 subunit, putative 0.0046 0.0241 0.3008
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0074 0.0445 0.4561
Trichomonas vaginalis set domain proteins, putative 0.0488 0.3417 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0011 0.0045
Brugia malayi conserved hypotetical protein 0.0014 0.0013 0.0014
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0076 0.046 0.1325
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0014 0.0011 0.0045
Mycobacterium tuberculosis Conserved protein 0.0072 0.0432 0.1207
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0089 0.0554 0.5619
Onchocerca volvulus 0.0047 0.0248 0.0688
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0047 0.0254 0.0602
Trypanosoma brucei glucose transporter 2A 0.0103 0.0651 0.8724
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0031
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0019 0.0025
Leishmania major glucose transporter/membrane transporter D2, putative 0.0103 0.0651 0.8311
Schistosoma mansoni transient receptor potential channel 0.0125 0.0811 0.1359
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0013 0.0016
Echinococcus multilocularis short transient receptor potential channel 6 0.0125 0.0811 0.1359
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0032 0.0071
Trichomonas vaginalis glucose transporter, putative 0.0103 0.0651 0.1886
Mycobacterium tuberculosis Conserved hypothetical protein 0.0016 0.0032 0.006
Echinococcus granulosus solute carrier family 22 0.0047 0.0248 0.0412
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0102 0.0642 0.0632
Echinococcus granulosus snurportin 1 0.06 0.4215 0.7085
Loa Loa (eye worm) hypothetical protein 0.0074 0.0445 0.1055
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0069
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0011 0.0045
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0011 0.0045
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0432 0.1244
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0241 0.0683
Trypanosoma brucei importin beta-1 subunit, putative 0.0056 0.0317 0.4191
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0014 0.0011 0.0043
Echinococcus multilocularis musashi 0.0026 0.0099 0.0161
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0013 0.0016
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.0579
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2057 0.6011
Loa Loa (eye worm) hypothetical protein 0.0056 0.0317 0.0752
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0021 0.0066 0.0106
Schistosoma mansoni transient receptor potential channel 0.0189 0.127 0.2131
Echinococcus multilocularis General substrate transporter 0.0285 0.1956 0.3286
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.0432 0.0722
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0032 0.0329
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2057 0.6011
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0076 0.046 0.5836
Brugia malayi Steroid receptor seven-up type 2 0.0029 0.0123 0.0331
Wolbachia endosymbiont of Brugia malayi Na+/H+-dicarboxylate symporter 0.05 0.3498 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0029 0.0123 0.0293
Onchocerca volvulus 0.0072 0.0432 0.1216
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0099 0.0235
Onchocerca volvulus 0.0059 0.0338 0.0945
Giardia lamblia Glycyl-tRNA synthetase 0.0019 0.0048 0.0178
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0013 0.0016
Echinococcus multilocularis dnaJ subfamily B 0.0841 0.5948 1
Toxoplasma gondii protein kinase, putative 0.0936 0.6628 1
Trypanosoma brucei glucose transporter, putative 0.0103 0.0651 0.8724
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0059
Echinococcus granulosus calcium dependent protein kinase 0.0095 0.0597 0.0998
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0011 0.0045
Toxoplasma gondii facilitative glucose transporter GT1 0.0331 0.2291 0.3444
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.105 0.1761
Plasmodium falciparum proline--tRNA ligase 0.0116 0.0745 0.0735
Echinococcus multilocularis lamin 0.0026 0.0099 0.0161
Brugia malayi nuclear hormone receptor 0.0014 0.0013 0.0014
Trichomonas vaginalis myo-inositol transporter, putative 0.0047 0.0248 0.0705
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0099 0.0627 0.1049
Trichomonas vaginalis sugar transporter, putative 0.0103 0.0651 0.1886
Loa Loa (eye worm) sugar transporter 0.0047 0.0248 0.0589
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0338 0.0801
Toxoplasma gondii thioredoxin reductase 0.0039 0.0195 0.0277
Onchocerca volvulus 0.0063 0.0364 0.1019
Echinococcus granulosus GTP binding nuclear protein Ran 0.0041 0.0211 0.0349
Schistosoma mansoni hypothetical protein 0.0049 0.0268 0.0445
Treponema pallidum fructose-bisphosphate aldolase 0.0299 0.2057 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0029 0.0123 0.0202
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0029 0.0123 0.0202
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0029 0.0043
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0166 0.0464
Trichomonas vaginalis helicase, putative 0.0013 0.001 0.0006
Mycobacterium ulcerans aldehyde dehydrogenase 0.0121 0.0782 0.8112
Brugia malayi Major Facilitator Superfamily protein 0.0047 0.0248 0.0688
Plasmodium vivax glutathione reductase, putative 0.0039 0.0195 0.0184
Echinococcus granulosus neuropeptide receptor A26 0.0474 0.3316 0.5573
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0029 0.0043
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0059
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0029 0.0123 0.0202
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0642 0.1074
Trypanosoma brucei trypanothione reductase 0.0039 0.0195 0.2533
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.0032 0.0329
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0432 0.5755
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0747 0.1771
Trypanosoma brucei glucose transporter, putative 0.0103 0.0651 0.8724
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0069
Schistosoma mansoni glycyl-tRNA synthetase 0.0019 0.0048 0.0074
Echinococcus multilocularis neuropeptide receptor A26 0.0474 0.3316 0.5573
Loa Loa (eye worm) hypothetical protein 0.0076 0.046 0.109
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0031
Echinococcus granulosus transient receptor potential ion channel A 0.0183 0.1225 0.2055
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0076 0.046 0.0768
Loa Loa (eye worm) hypothetical protein 0.0047 0.0248 0.0589
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.046 0.6126
Trypanosoma cruzi hexose transporter, putative 0.0047 0.0248 0.3259
Brugia malayi hypothetical protein 0.0015 0.0025 0.0048
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0029 0.0123 0.0202
Trypanosoma brucei glucose transporter, putative 0.0103 0.0651 0.8724
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0031
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0036 0.0054
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0041 0.0211 0.05
Brugia malayi nuclear receptor RXR 0.0014 0.0013 0.0014
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0061 0.0098
Loa Loa (eye worm) hypothetical protein 0.0101 0.0642 0.1523
Brugia malayi nuclear receptor NHR-88 0.0014 0.0013 0.0014
Schistosoma mansoni survival motor neuron protein 0.0049 0.0268 0.0445
Plasmodium falciparum calcium-dependent protein kinase 1 0.0102 0.0642 0.0632
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.0432 0.1207
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0013 0.0031
Leishmania major hypothetical protein, conserved 0.0016 0.0029 0.0273
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0013 0.0016
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0029 0.0123 0.0202
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0099 0.0626 0.1762
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0166 0.0274
Toxoplasma gondii glycyl-tRNA synthetase 0.0019 0.0048 0.0055
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0146 0.0961 0.2724
Loa Loa (eye worm) hypothetical protein 0.0047 0.0248 0.0589
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0747 0.1771
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.105 0.2986
Trichomonas vaginalis sugar transport protein, putative 0.0047 0.0248 0.0705
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0029 0.0043
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0128 0.0829 0.1388
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0031
Echinococcus granulosus solute carrier family 22 0.0047 0.0248 0.0412
Loa Loa (eye worm) hypothetical protein 0.0145 0.0956 0.2268
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.001 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0029 0.0123 0.0331
Plasmodium falciparum ataxin-2 like protein, putative 0.0047 0.0254 0.0243
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0029 0.0123 0.0331
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0102 0.0642 0.0953
Trypanosoma brucei glucose transporter, putative 0.0103 0.0651 0.8724
Echinococcus granulosus calcium activated potassium channel 0.0013 0.0005 0.0002
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.0432 0.1207
Echinococcus granulosus GPCR family 2 0.0015 0.0019 0.0025
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0047 0.0248 0.2494
Echinococcus multilocularis transient receptor potential gamma protein 0.0189 0.127 0.2131
Loa Loa (eye worm) hypothetical protein 0.0047 0.0248 0.0589
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0146 0.0961 1
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0029 0.0027
Leishmania major hypothetical protein, conserved 0.0072 0.0432 0.5482
Onchocerca volvulus 0.0029 0.0123 0.0331
Onchocerca volvulus 0.0049 0.0268 0.0744
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0029 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0029 0.0123 0.0331
Loa Loa (eye worm) hypothetical protein 0.007 0.0419 0.0993
Brugia malayi jmjC domain containing protein 0.006 0.0345 0.0967
Onchocerca volvulus 0.0047 0.0248 0.0688
Onchocerca volvulus 0.0047 0.0248 0.0688
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0031
Toxoplasma gondii LsmAD domain-containing protein 0.0047 0.0254 0.0366
Loa Loa (eye worm) DR-78 0.0014 0.0013 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0029 0.0123 0.0331
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0099 0.0627 0.6403
Brugia malayi Excitatory amino acid transporter 0.05 0.3498 1
Mycobacterium ulcerans lipase LipD 0.0072 0.0432 0.4432
Mycobacterium ulcerans aldehyde dehydrogenase 0.0121 0.0782 0.8112
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0013 0.0016
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0041 0.0211 0.0974
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0006
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0364 0.0606
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0029 0.0123 0.0202
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0019 0.0048 0.0105
Entamoeba histolytica hypothetical protein 0.0046 0.0241 0.1136
Onchocerca volvulus Excitatory amino acid transporter homolog 0.05 0.3498 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0031
Giardia lamblia Threonyl-tRNA synthetase 0.0019 0.0048 0.0178
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0364 0.0606
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0569 0.0951
Loa Loa (eye worm) hypothetical protein 0.0047 0.0248 0.0589
Trypanosoma brucei THT1 - hexose transporter, putative 0.0103 0.0651 0.8724
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0166 0.0394
Schistosoma mansoni protein kinase 0.0101 0.0642 0.1074
Schistosoma mansoni solute carrier family 1 (glial high affinity glutamate transporter 0.05 0.3498 0.5879
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0029 0.0123 0.0331
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0364 0.0606
Echinococcus multilocularis calcium dependent protein kinase 0.0095 0.0597 0.0998
Trichomonas vaginalis conserved hypothetical protein 0.0331 0.2291 0.6695
Brugia malayi nuclear receptor NHR-67 0.0014 0.0013 0.0014
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0099 0.0627 0.1774
Trypanosoma brucei THT1 - hexose transporter, putative 0.0103 0.0651 0.8724
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0063 0.0365 0.1013
Brugia malayi intermediate filament protein 0.0026 0.0099 0.0261
Trypanosoma brucei glucose transporter, putative 0.0103 0.0651 0.8724
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0029 0.0123 0.0202
Trichomonas vaginalis importin beta-1, putative 0.0046 0.0241 0.0683
Schistosoma mansoni lysyl-tRNA synthetase 0.0074 0.0445 0.0742
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0116 0.0745 0.9526
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0221 0.1503 0.2522
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0569 0.0951
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0039 0.0195 0.0526
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0099 0.0627 0.1049
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0031
Schistosoma mansoni hypothetical protein 0.0841 0.5948 1
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0013 0.0016
Schistosoma mansoni cpg binding protein 0.0059 0.0338 0.0562
Schistosoma mansoni lysyl-tRNA synthetase 0.0074 0.0445 0.0742
Echinococcus multilocularis neutral amino acid transporter A 0.05 0.3498 0.5879
Brugia malayi hypothetical protein 0.0047 0.0248 0.0688
Leishmania major myo-inositol/proton symporter (MIT) 0.0047 0.0248 0.3105
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0014 0.0011 0.0013
Echinococcus multilocularis short transient receptor potential channel 6 0.0125 0.0811 0.1359
Brugia malayi jmjC domain containing protein 0.0016 0.0029 0.0061
Echinococcus multilocularis TRP (transient receptor potential) channel 0.007 0.0419 0.0698
Echinococcus granulosus short transient receptor potential channel 6 0.0125 0.0811 0.1359
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0059
Loa Loa (eye worm) hypothetical protein 0.0047 0.0248 0.0589
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0019 0.0048 0.0384
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0029 0.0043
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0013 0.0016
Entamoeba histolytica protein kinase, putative 0.0101 0.0642 0.3092
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Schistosoma mansoni zinc finger protein 0.0014 0.0013 0.0016
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.0432 0.1207
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0569 0.0951
Chlamydia trachomatis glutamate symporter 0.05 0.3498 1
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0014 0.0011 0.0043
Echinococcus granulosus lamin dm0 0.0026 0.0099 0.0161
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0013 0.0015
Brugia malayi jmjC domain containing protein 0.0016 0.0029 0.0061
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0013 0.0031
Loa Loa (eye worm) hypothetical protein 0.0099 0.0627 0.1488
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0102 0.0642 0.0953
Leishmania major lysyl-tRNA synthetase, putative 0.0074 0.0445 0.5641
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0123 0.0202
Toxoplasma gondii sugar transporter ST2 0.0047 0.0248 0.0358
Schistosoma mansoni transient receptor potential channel 4 0.0189 0.127 0.2131
Echinococcus granulosus intermediate filament protein 0.0026 0.0099 0.0161
Loa Loa (eye worm) glutathione reductase 0.0039 0.0195 0.0462
Trypanosoma cruzi PAB1-binding protein , putative 0.0047 0.0254 0.3333
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0041 0.0211 0.02
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0047 0.0248 0.0412
Echinococcus granulosus TRP transient receptor potential channel 0.007 0.0419 0.0698
Onchocerca volvulus 0.0026 0.0099 0.0261
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0076 0.046 0.1294
Chlamydia trachomatis lysine--tRNA ligase 0.0074 0.0445 0.1242
Schistosoma mansoni coup transcription factor 0.0029 0.0123 0.0202
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Echinococcus multilocularis excitatory amino acid transporter 2 0.05 0.3498 0.5879
Trypanosoma cruzi trypanothione reductase, putative 0.0014 0.0011 0.0045
Echinococcus multilocularis solute carrier family 22 0.0047 0.0248 0.0412
Loa Loa (eye worm) major facilitator superfamily transporter 0.0047 0.0248 0.0589
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0016 0.0032 0.0032
Brugia malayi Muscleblind-like protein 0.0145 0.0956 0.2716
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0101 0.0642 0.1074
Trypanosoma cruzi glucose transporter, putative 0.0047 0.0248 0.3259
Onchocerca volvulus 0.0072 0.0432 0.1216
Loa Loa (eye worm) hypothetical protein 0.0047 0.0248 0.0589
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0029 0.0123 0.0331
Leishmania major hypothetical protein, conserved 0.0016 0.0032 0.0313
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0569 0.095
Schistosoma mansoni glucose transporter 0.0047 0.0248 0.0412
Loa Loa (eye worm) hypothetical protein 0.0119 0.0766 0.1817
Schistosoma mansoni glucose transport protein 0.0331 0.2291 0.3847
Schistosoma mansoni cpg binding protein 0.0062 0.0362 0.0603
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2057 0.6011
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0331 0.2291 0.3848
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0432 0.1244
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0461 0.3224 0.9216
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0019 0.0025
Schistosoma mansoni hypothetical protein 0.0015 0.0019 0.0025
Schistosoma mansoni glucose transport protein 0.0331 0.2291 0.3847
Onchocerca volvulus 0.0047 0.0248 0.0688
Loa Loa (eye worm) hypothetical protein 0.0029 0.0123 0.0293
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0046 0.0244 0.0676
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0031
Treponema pallidum glutamate/aspartate transporter 0.0221 0.1503 0.7288
Echinococcus multilocularis muscleblind protein 0.0145 0.0956 0.1602
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.0432 0.1026
Leishmania major threonyl-tRNA synthetase, putative 0.0019 0.0048 0.0514
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0041 0.0211 0.02
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0076 0.046 0.0767
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.0345 0.0575
Giardia lamblia Lysyl-tRNA synthetase 0.0074 0.0445 0.2117
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0019 0.0048 0.0114
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0146 0.0961 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0114 0.0733 0.109
Onchocerca volvulus 0.0047 0.0248 0.0688
Plasmodium falciparum protein kinase 7 0.0936 0.6628 0.6624
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0035 0.0166 0.1628
Brugia malayi follicle stimulating hormone receptor 0.0228 0.1547 0.4409
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0221 0.1503 0.2522
Brugia malayi jmjC domain containing protein 0.0016 0.0029 0.0061
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2057 0.6011
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0651 0.1886
Onchocerca volvulus Putative transporter 0.0047 0.0248 0.0688
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2057 0.6011
Schistosoma mansoni hypothetical protein 0.0331 0.2291 0.3847
Mycobacterium ulcerans beta-lactamase 0.0072 0.0432 0.4432
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.001 0.0006
Echinococcus multilocularis Excitatory amino acid transporter 0.05 0.3498 0.5879
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0569 0.095
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Giardia lamblia Prolyl-tRNA synthetase 0.0099 0.0627 0.3009
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0076 0.046 0.0767
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.0345 0.0575
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0046 0.0244 0.0579
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0642 0.1074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0029 0.0123 0.0293
Leishmania major trypanothione reductase 0.0039 0.0195 0.2413
Brugia malayi beta-lactamase 0.0072 0.0432 0.1216
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Mycobacterium tuberculosis Conserved protein 0.0072 0.0432 0.1207
Onchocerca volvulus 0.0072 0.0432 0.1216
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0047 0.0248 0.0679
Echinococcus multilocularis solute carrier family 22 0.0047 0.0248 0.0412
Echinococcus granulosus lysine specific demethylase 5A 0.0063 0.037 0.0616
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0089 0.0554 0.1557
Mycobacterium tuberculosis Probable C4-dicarboxylate-transport transmembrane protein DctA 0.05 0.3498 1
Leishmania major hypothetical protein, conserved 0.0047 0.0248 0.3105
Leishmania major glucose transporter, lmgt1 0.0103 0.0651 0.8311
Echinococcus granulosus survival motor neuron protein 1 0.0242 0.1648 0.2767
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0569 0.095
Plasmodium vivax hexose transporter 0.0331 0.2291 0.2282
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0019 0.0048 0.0167
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0013 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0642 0.1074
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0248 0.0705
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0101 0.0642 0.8597
Echinococcus multilocularis transient receptor potential ion channel A 0.0183 0.1225 0.2055
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0041 0.0211 0.2749
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0019 0.0048 0.0113
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0019 0.0048 0.0384
Schistosoma mansoni glucose transport protein 0.0331 0.2291 0.3847
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0041 0.0211 0.0349
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0013 0.0014
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.046 0.6126
Onchocerca volvulus 0.0047 0.0248 0.0688
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0029 0.0123 0.0293
Brugia malayi MH2 domain containing protein 0.0116 0.0747 0.2116
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0019 0.0048 0.0114
Brugia malayi ecdysteroid receptor 0.0029 0.0123 0.0331
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0032 0.0071
Loa Loa (eye worm) hypothetical protein 0.0072 0.0432 0.1026
Echinococcus multilocularis solute carrier family 22 0.0047 0.0248 0.0412
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0029 0.0123 0.0331
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.0432 0.1207
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0029 0.0123 0.0293
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0569 0.1606
Giardia lamblia Fructose-bisphosphate aldolase 0.0299 0.2057 1
Onchocerca volvulus 0.0488 0.3417 0.977
Echinococcus granulosus excitatory amino acid transporter 2 0.05 0.3498 0.5879
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.0432 0.4432
Loa Loa (eye worm) hypothetical protein 0.0025 0.0096 0.0227
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0029 0.0043
Echinococcus granulosus neutral amino acid transporter A 0.05 0.3498 0.5879
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0076 0.046 0.1325
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.0432 0.1216
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0013 0.0016
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.0032 0.0329
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0113
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0121 0.0782 0.131
Brugia malayi hypothetical protein 0.0047 0.0254 0.0704
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0076 0.046 0.0768
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0013 0.0014
Toxoplasma gondii sugar transporter ST1 0.0047 0.0248 0.0358
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0029 0.0286
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.037 0.0877
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0432 0.0721
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0331 0.2291 0.3848
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0047 0.0248 0.2494
Brugia malayi Pre-SET motif family protein 0.0429 0.2993 0.8554
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0101 0.0642 0.1523
Schistosoma mansoni hypothetical protein 0.0021 0.0066 0.0106
Entamoeba histolytica Ran family GTPase 0.0041 0.0211 0.0989
Echinococcus multilocularis cpg binding protein 0.0062 0.0362 0.0603
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0029 0.0123 0.0293
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0121 0.0782 0.131
Toxoplasma gondii ABC1 family protein 0.0072 0.0432 0.0636
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0651 0.1886
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0166 0.0464
Brugia malayi Nuclear hormone receptor-like 1 0.0015 0.0025 0.0048
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0021 0.0066 0.0106
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0031
Trypanosoma brucei THT1 - hexose transporter, putative 0.0103 0.0651 0.8724
Trypanosoma brucei PAB1-binding protein , putative 0.0047 0.0254 0.3333
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0268 0.0744
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0364 0.0533
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0432 0.5755
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0166 0.0464
Loa Loa (eye worm) excitatory amino acid transporter 0.05 0.3498 0.8299
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0015 0.0025 0.0036
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0029 0.0286
Treponema pallidum prolyl-tRNA synthetase 0.0035 0.0166 0.0756
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0063 0.0365 0.3578
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0013 0.0014
Echinococcus granulosus cpg binding protein 0.0062 0.0362 0.0603
Schistosoma mansoni transient receptor potential channel 0.0125 0.0811 0.1359
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0121 0.0782 0.221
Loa Loa (eye worm) hypothetical protein 0.0145 0.0956 0.2268
Plasmodium falciparum hexose transporter 0.0331 0.2291 0.2282
Echinococcus granulosus importin subunit beta 1 0.0056 0.0317 0.0528
Brugia malayi CXXC zinc finger family protein 0.0059 0.0338 0.0945
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0029 0.0123 0.0331
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Trypanosoma brucei glucose transporter, putative 0.0103 0.0651 0.8724
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0076 0.046 0.2191
Onchocerca volvulus 0.0014 0.0013 0.0014
Plasmodium falciparum importin beta, putative 0.0056 0.0317 0.0306
Brugia malayi hypothetical protein 0.0014 0.0013 0.0014
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0099 0.0627 0.1816
Schistosoma mansoni hypothetical protein 0.0031 0.014 0.0229
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0102 0.0642 0.0953
Brugia malayi nuclear receptor NHR-88 0.0029 0.0123 0.0331
Schistosoma mansoni sugar transporter 0.0047 0.0248 0.0412
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0102 0.0642 0.0632
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.001 0.0006
Schistosoma mansoni lamin 0.0026 0.0099 0.0161
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0432 0.1244
Plasmodium vivax importin-beta 2, putative 0.0056 0.0317 0.0306
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0019 0.003
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0029 0.0043
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0116 0.0745 0.1109
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Trypanosoma cruzi hexose transporter, putative 0.0103 0.0651 0.8724
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.001 0.0006
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0013 0.0014
Schistosoma mansoni steroid hormone receptor ad4bp 0.0029 0.0123 0.0202
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0569 0.1349
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0019 0.0048 0.054
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0011 0.0045
Plasmodium vivax calcium-dependent protein kinase, putative 0.0102 0.0642 0.0632
Plasmodium falciparum thioredoxin reductase 0.0039 0.0195 0.0184
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2057 0.6011
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0013 0.0016
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0166 0.0464
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0011 0.0043
Plasmodium falciparum threonine--tRNA ligase 0.0019 0.0048 0.0036
Loa Loa (eye worm) hypothetical protein 0.0029 0.0123 0.0293
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0008
Brugia malayi steroid hormone receptor 0.0029 0.0123 0.0331
Loa Loa (eye worm) hypothetical protein 0.0099 0.0627 0.1488
Schistosoma mansoni hypothetical protein 0.0015 0.0019 0.0025
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.0432 0.1207
Schistosoma mansoni nuclear receptor 0.0014 0.0013 0.0016
Mycobacterium tuberculosis Probable dehydrogenase 0.0089 0.0554 0.1557
Loa Loa (eye worm) hypothetical protein 0.0047 0.0248 0.0589
Schistosoma mansoni sugar transporter 0.0047 0.0248 0.0412
Mycobacterium tuberculosis Conserved protein 0.0072 0.0432 0.1207
Plasmodium vivax SET domain protein, putative 0.0063 0.0364 0.0353
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0047 0.0248 0.3259
Echinococcus multilocularis ecdysone induced protein 78C 0.0029 0.0123 0.0202
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0029 0.0123 0.0202
Schistosoma mansoni aldehyde dehydrogenase 0.0121 0.0782 0.1309
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0031
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0041 0.0211 0.0301
Plasmodium vivax lysine--tRNA ligase, putative 0.0074 0.0445 0.0434
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0053 0.0084
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0166 0.0464
Echinococcus multilocularis muscleblind protein 1 0.0145 0.0956 0.1602
Echinococcus granulosus ubiquitin specific protease 41 0.0076 0.046 0.0768
Trichomonas vaginalis mercuric reductase, putative 0.0014 0.0011 0.001
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0015 0.0025 0.0035
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0019 0.0048 0.0105
Schistosoma mansoni ran 0.0041 0.0211 0.0348
Toxoplasma gondii transporter, major facilitator family protein 0.0047 0.0248 0.0358
Mycobacterium ulcerans integral membrane transport protein 0.0047 0.0248 0.2494
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0074 0.0445 0.4439
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0014 0.0011 0.0045
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0429 0.2993 0.7102
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0099 0.0627 0.1049
Schistosoma mansoni ran 0.0041 0.0211 0.0348
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0089 0.0554 0.1557
Brugia malayi hypothetical protein 0.0031 0.0133 0.0359
Trypanosoma brucei glucose transporter 1E 0.0103 0.0651 0.8724
Brugia malayi beta-lactamase family protein 0.0072 0.0432 0.1216
Echinococcus multilocularis lysyl tRNA synthetase 0.0074 0.0445 0.0742
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Onchocerca volvulus 0.0047 0.0248 0.0688
Plasmodium vivax CDK-related protein kinase 6, putative 0.1406 1 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0166 0.0772
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0029 0.0027
Plasmodium falciparum calcium-dependent protein kinase 2 0.0102 0.0642 0.0632
Echinococcus multilocularis synaptic vesicle 2 protein 0.0047 0.0248 0.0412
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0364 0.0606
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.046 0.1325
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0063 0.0365 0.1013
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0029 0.0123 0.0293
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0338 0.0563
Echinococcus granulosus Sugar transporter ERD6 protein 0.0047 0.0248 0.0412
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2057 0.6011
Trichomonas vaginalis ran, putative 0.0041 0.0211 0.0594
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Onchocerca volvulus 0.0047 0.0248 0.0688
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0029 0.0123 0.0331
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0166 0.0464
Trypanosoma cruzi hexose transporter, putative 0.0103 0.0651 0.8724
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.0432 0.0722
Schistosoma mansoni protein kinase 0.0101 0.0642 0.1074
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0014 0.0011 0.0013
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0047 0.0248 0.0412
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0029 0.0123 0.0331
Plasmodium falciparum calcium-dependent protein kinase 4 0.0102 0.0642 0.0632
Onchocerca volvulus Protein ultraspiracle homolog 0.0029 0.0123 0.0331
Brugia malayi RNA, U transporter 1 0.016 0.106 0.3014
Echinococcus multilocularis GPCR, family 2 0.0015 0.0019 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0032 0.0071
Mycobacterium tuberculosis Probable oxidoreductase 0.0099 0.0626 0.1762
Brugia malayi tailless protein 0.0014 0.0013 0.0014
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0036 0.0054
Plasmodium falciparum calcium-dependent protein kinase 5 0.0102 0.0642 0.0632
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0029 0.0043
Echinococcus multilocularis excitatory amino acid transporter 2 0.05 0.3498 0.5879
Onchocerca volvulus 0.0047 0.0248 0.0688
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0029 0.0123 0.0331
Trichomonas vaginalis sugar transporter, putative 0.0103 0.0651 0.1886
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0099 0.0627 0.1049
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Loa Loa (eye worm) hypothetical protein 0.0047 0.0248 0.0589
Brugia malayi hypothetical protein 0.0015 0.0025 0.0048
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0019 0.0048 0.0075
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.037 0.0616
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0432 0.1244
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0013 0.0016
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0013 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0248 0.0705
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0041 0.0207 0.0491
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0006
Leishmania major hypothetical protein, conserved 0.0016 0.0032 0.0313
Schistosoma mansoni hypothetical protein 0.0015 0.0019 0.0025
Onchocerca volvulus 0.0014 0.0013 0.0014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.001 0.0006
Brugia malayi hypothetical protein 0.0047 0.0248 0.0688
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0019 0.0048 0.0105
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0013 0.0014
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0019 0.0044
Brugia malayi Major Facilitator Superfamily protein 0.0047 0.0248 0.0688
Echinococcus multilocularis sodium:dicarboxylate symporter 0.05 0.3498 0.5879
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0036 0.0054
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0019 0.0025
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0029 0.0069
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0123 0.0202
Loa Loa (eye worm) hypothetical protein 0.0064 0.0373 0.0886
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0015 0.0025 0.0036
Loa Loa (eye worm) hypothetical protein 0.0072 0.0432 0.1026
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0013 0.0016
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0099 0.0235
Schistosoma mansoni jumonji/arid domain-containing protein 0.0063 0.037 0.0616
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0166 0.0453
Brugia malayi glutathione reductase 0.0039 0.0195 0.0535
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0047 0.0248 0.0237
Loa Loa (eye worm) hypothetical protein 0.0072 0.0432 0.1026
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0221 0.1503 0.2522
Schistosoma mansoni sugar transporter 0.0047 0.0248 0.0412
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Echinococcus granulosus muscleblind protein 0.0145 0.0956 0.1602
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0019 0.0048 0.054
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0432 0.0721
Treponema pallidum glutamate transporter 0.0221 0.1503 0.7288
Treponema pallidum threonyl-tRNA synthetase 0.0019 0.0048 0.0178
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0166 0.0772
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0241 0.0683
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0642 0.1074
Plasmodium falciparum mitogen-activated protein kinase 2 0.0535 0.3754 0.3747
Schistosoma mansoni importin beta-1 0.0056 0.0317 0.0527
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0011 0.0043
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0364 0.0606
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.001 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0029 0.0123 0.0331
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0099 0.0627 0.1774
Plasmodium vivax JmjC domain containing protein 0.0016 0.0029 0.0018
Loa Loa (eye worm) hypothetical protein 0.0072 0.0432 0.1026
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.05 0.3498 0.5879
Brugia malayi lysyl-tRNA synthetase 0.0074 0.0445 0.1251
Echinococcus multilocularis neutral amino acid transporter A 0.05 0.3498 0.5879
Mycobacterium ulcerans hypothetical protein 0.0016 0.0032 0.022
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0299 0.2057 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0029 0.0123 0.0202
Brugia malayi major facilitator superfamily protein 0.0047 0.0248 0.0688
Trypanosoma brucei sugar transporter, putative 0.0047 0.0248 0.3259
Echinococcus multilocularis glycyl tRNA synthetase 0.0019 0.0048 0.0075
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Brugia malayi ecdysone receptor 0.0014 0.0013 0.0014
Onchocerca volvulus 0.0047 0.0248 0.0688
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0642 0.1859
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0013 0.0016
Plasmodium vivax threonine--tRNA ligase, putative 0.0019 0.0048 0.0036
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0642 0.1074
Echinococcus granulosus neutral amino acid transporter 0.05 0.3498 0.5879
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0029 0.0123 0.0202
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0015 0.0025 0.0035
Leishmania major protein kinase, putative 0.0101 0.0642 0.819
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Echinococcus multilocularis thyroid hormone receptor alpha 0.0029 0.0123 0.0202
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0331 0.2291 0.3848
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0069
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0116 0.0745 1
Mycobacterium tuberculosis Probable reductase 0.0089 0.0554 0.1557
Loa Loa (eye worm) beta-lactamase 0.0072 0.0432 0.1026
Echinococcus multilocularis FTZ F1 alpha 0.0029 0.0123 0.0202
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0076 0.046 0.2203
Loa Loa (eye worm) hypothetical protein 0.0047 0.0248 0.0589
Schistosoma mansoni protein kinase 0.0101 0.0642 0.1074
Echinococcus granulosus ecdysone induced protein 78C 0.0029 0.0123 0.0202
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0019 0.0048 0.0055
Echinococcus multilocularis survival motor neuron protein 1 0.0242 0.1648 0.2767
Schistosoma mansoni RAR-like nuclear receptor 0.0029 0.0123 0.0202
Toxoplasma gondii lysine-tRNA ligase 0.0074 0.0445 0.0655
Trichomonas vaginalis glutathione reductase, putative 0.0014 0.0011 0.001
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0029 0.0123 0.0202
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0099 0.0627 0.3021
Brugia malayi Sugar transporter family protein 0.0047 0.0248 0.0688
Loa Loa (eye worm) hypothetical protein 0.0072 0.0432 0.1026
Brugia malayi Importin beta-1 subunit 0.0056 0.0317 0.0885
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0569 0.0951
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0029 0.0043
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0331 0.2291 0.3848
Plasmodium falciparum calcium-dependent protein kinase 3 0.0102 0.0642 0.0632
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0432 0.5755
Onchocerca volvulus 0.0092 0.0571 0.1614
Loa Loa (eye worm) hypothetical protein 0.0047 0.0248 0.0589
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0031
Mycobacterium ulcerans hypothetical protein 0.0072 0.0432 0.4432
Brugia malayi Nuclear hormone receptor-like 1 0.0015 0.0025 0.0048
Trypanosoma cruzi sugar transporter, putative 0.0047 0.0248 0.3259
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0029 0.0123 0.0331
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.06 0.4215 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0029 0.0123 0.0202
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0299 0.2057 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0015 0.0025 0.0059
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0166 0.0274
Onchocerca volvulus 0.0026 0.0099 0.0261
Brugia malayi Sugar transporter family protein 0.0331 0.2291 0.654
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0036 0.0054
Brugia malayi jmjC domain containing protein 0.0016 0.0029 0.0061
Plasmodium falciparum glutathione reductase 0.0039 0.0195 0.0184
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0166 0.0464
Schistosoma mansoni alpha-glucosidase 0.0136 0.0892 0.1495
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0019 0.0048 0.054
Loa Loa (eye worm) hypothetical protein 0.0029 0.0123 0.0293
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0041 0.0211 0.0581
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0102 0.0642 0.0632
Loa Loa (eye worm) hypothetical protein 0.0029 0.0123 0.0293
Echinococcus granulosus Excitatory amino acid transporter 0.05 0.3498 0.5879
Plasmodium falciparum lysine--tRNA ligase 0.0074 0.0445 0.0434
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0123 0.0202
Trypanosoma brucei glucosidase, putative 0.0035 0.0166 0.2146
Echinococcus granulosus neutral amino acid transporter A 0.05 0.3498 0.5879
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0331 0.2291 0.3848
Trypanosoma cruzi hexose transporter, putative 0.0056 0.0317 0.4191
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0011 0.0045
Brugia malayi nuclear hormone receptor 0.0029 0.0123 0.0331
Toxoplasma gondii HEAT repeat-containing protein 0.0056 0.0317 0.0462
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0166 0.2146
Echinococcus multilocularis neutral amino acid transporter A 0.05 0.3498 0.5879
Schistosoma mansoni thyroid hormone receptor 0.0029 0.0123 0.0202
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0166 0.2044
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0047 0.0248 0.0589
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.105 0.1761
Schistosoma mansoni lamin 0.0026 0.0099 0.0161
Echinococcus granulosus phd:f box containing protein 0.0016 0.0029 0.0043
Trichomonas vaginalis sugar transporter, putative 0.0103 0.0651 0.1886
Loa Loa (eye worm) steroid hormone receptor 0.0029 0.0123 0.0293
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0019 0.0048 0.054
Echinococcus multilocularis snurportin 1 0.06 0.4215 0.7085
Loa Loa (eye worm) major facilitator superfamily transporter 0.0047 0.0248 0.0589
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0059
Schistosoma mansoni hypothetical protein 0.0015 0.0019 0.0025
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0036 0.0054
Loa Loa (eye worm) thioredoxin reductase 0.0039 0.0195 0.0462
Brugia malayi Sugar transporter family protein 0.0047 0.0248 0.0688
Leishmania major glucose transporter, lmgt2 0.0103 0.0651 0.8311
Echinococcus granulosus General substrate transporter 0.0285 0.1956 0.3286
Echinococcus granulosus Excitatory amino acid transporter 0.05 0.3498 0.5879
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.006 0.0148
Brugia malayi hypothetical protein 0.0047 0.0248 0.0688
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0019 0.0048 0.0113
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0074 0.0445 0.5922
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0331 0.2291 0.3848
Brugia malayi Transient-receptor-potential like protein 0.007 0.0419 0.1176
Leishmania major hypothetical protein, conserved 0.0047 0.0254 0.3175
Loa Loa (eye worm) sugar transporter 0.0331 0.2291 0.5434
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0029 0.0123 0.0202
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0029 0.0018
Echinococcus multilocularis lamin dm0 0.0026 0.0099 0.0161
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0364 0.0606
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0006
Schistosoma mansoni cpg binding protein 0.0062 0.0362 0.0603
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0029 0.0123 0.0293
Plasmodium vivax sugar transporter, putative 0.0047 0.0248 0.0237
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0019 0.0048 0.0194
Loa Loa (eye worm) hypothetical protein 0.0047 0.0248 0.0589
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0013 0.0016
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0019 0.0048 0.0194
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0029 0.0043
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0065 0.0379 0.1089
Echinococcus granulosus sodium:dicarboxylate symporter 0.05 0.3498 0.5879
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0166 0.0464
Echinococcus granulosus neuropeptide s receptor 0.0474 0.3316 0.5573
Echinococcus multilocularis importin subunit beta 1 0.0056 0.0317 0.0528
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0047 0.0248 0.0679
Trypanosoma brucei importin beta-1 subunit, putative 0.0056 0.0317 0.4191
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0228 0.1547 0.3669
Loa Loa (eye worm) hypothetical protein 0.0081 0.0493 0.1171
Brugia malayi latrophilin 2 splice variant baaae 0.0031 0.014 0.0377
Brugia malayi photoreceptor-specific nuclear receptor 0.0029 0.0123 0.0331
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0829 0.5861 0.9854
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0166 0.2146
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0019 0.0048 0.0117
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.046 0.6126
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0642 0.1074
Entamoeba histolytica protein kinase, putative 0.0101 0.0642 0.3092
Schistosoma mansoni alpha-glucosidase 0.0136 0.0892 0.1495
Trypanosoma cruzi importin beta-1 subunit, putative 0.0046 0.0241 0.3158
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0101 0.0642 0.1816
Chlamydia trachomatis threonine--tRNA ligase 0.0019 0.0048 0.0105
Loa Loa (eye worm) hypothetical protein 0.0015 0.0019 0.0044
Brugia malayi hypothetical protein 0.0014 0.0013 0.0014
Leishmania major glucose transporter, lmgt3 0.0103 0.0651 0.8311
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0006
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0101 0.0642 0.1523
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0029 0.0123 0.0331
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Schistosoma mansoni hypothetical protein 0.06 0.4215 0.7085
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0076 0.046 0.0768
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0014 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0026 0.0099 0.0235
Trypanosoma cruzi PAB1-binding protein , putative 0.0047 0.0254 0.3333
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.0345 0.0575
Brugia malayi Calcitonin receptor-like protein seb-1 0.0046 0.0244 0.0676
Brugia malayi glycyl-tRNA synthetase 0.0019 0.0048 0.0114
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0031
Echinococcus multilocularis solute carrier family 22 0.0047 0.0248 0.0412
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0116 0.0745 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0013 0.0014
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0432 0.0421
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0248 0.0705
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0029 0.0286
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0642 0.1074
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0535 0.3754 0.5656
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0248 0.0705
Chlamydia trachomatis proline--tRNA ligase 0.0035 0.0166 0.0443
Toxoplasma gondii aldehyde dehydrogenase 0.0121 0.0782 0.1164
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.105 0.2492
Trypanosoma brucei glucose transporter, putative 0.0103 0.0651 0.8724
Echinococcus granulosus lamin 0.0026 0.0099 0.0161
Schistosoma mansoni sugar transporter 0.0047 0.0248 0.0412
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.0432 0.4432
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0166 0.0464
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0074 0.0445 0.4561
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0041 0.0211 0.2749
Loa Loa (eye worm) hypothetical protein 0.0029 0.0123 0.0293
Trypanosoma cruzi hexose transporter, putative 0.0103 0.0651 0.8724
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0123 0.0202
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0364 0.0606
Brugia malayi Pre-SET motif family protein 0.0063 0.0364 0.1019
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0166 0.0234
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.2057 0.6011
Trypanosoma cruzi trypanothione reductase, putative 0.0039 0.0195 0.2533
Onchocerca volvulus 0.0047 0.0248 0.0688
Brugia malayi nuclear receptor RXR 0.0015 0.0025 0.0048
Loa Loa (eye worm) hypothetical protein 0.0242 0.1648 0.391
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0535 0.3754 0.3747
Echinococcus multilocularis thioredoxin glutathione reductase 0.004 0.0198 0.0328
Echinococcus multilocularis excitatory amino acid transporter 3 0.05 0.3498 0.5879
Leishmania major GTP-binding protein, putative 0.0041 0.0211 0.2618
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0123 0.0202
Schistosoma mansoni intermediate filament proteins 0.0026 0.0099 0.0161
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0074 0.0445 0.128
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0019 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0047 0.0248 0.0589
Echinococcus granulosus dnaJ subfamily B 0.0841 0.5948 1
Echinococcus granulosus excitatory amino acid transporter 2 0.05 0.3498 0.5879
Brugia malayi jmjC domain containing protein 0.0063 0.037 0.1036
Echinococcus multilocularis calcium activated potassium channel 0.0013 0.0005 0.0002
Trichomonas vaginalis glucose transporter, putative 0.0103 0.0651 0.1886
Plasmodium falciparum ataxin-2 like protein, putative 0.0047 0.0254 0.0243
Echinococcus granulosus glycyl tRNA synthetase 0.0019 0.0048 0.0075
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0014 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0031
Brugia malayi major facilitator superfamily protein 0.0047 0.0248 0.0688
Trichomonas vaginalis esterase, putative 0.0072 0.0432 0.1244
Echinococcus multilocularis Excitatory amino acid transporter 0.05 0.3498 0.5879
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.0032 0.0329
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0248 0.0705
Loa Loa (eye worm) hypothetical protein 0.0063 0.0364 0.0863
Schistosoma mansoni retinoic acid receptor RXR 0.0029 0.0123 0.0202
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0013 0.0031
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0047 0.0248 0.0679
Brugia malayi beta-lactamase family protein 0.0072 0.0432 0.1216

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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