Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | TAR-binding protein | 0.0066 | 0.3065 | 0.3053 |
Loa Loa (eye worm) | RNA binding protein | 0.0066 | 0.3065 | 0.3053 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0066 | 0.3065 | 0.3053 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.3065 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.3065 | 1 |
Entamoeba histolytica | Ras guanine nucleotide exchange factor, putative | 0.0007 | 0.0018 | 0.5 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.001 | 0.0164 | 0.0146 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.001 | 0.0164 | 0.048 |
Trichomonas vaginalis | ras GTP exchange factor, son of sevenless, putative | 0.0007 | 0.0018 | 0.5 |
Entamoeba histolytica | Ras guanine nucleotide exchange factor, putative | 0.0007 | 0.0018 | 0.5 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0007 | 0.0018 | 0.0058 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0066 | 0.3065 | 0.3053 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.001 | 0.0164 | 0.048 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 1 | 1 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.001 | 0.0164 | 0.0146 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.001 | 0.0164 | 0.048 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0007 | 0.0018 | 0.0058 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.001 | 0.0164 | 0.0146 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.001 | 0.0164 | 0.048 |
Onchocerca volvulus | Segment polarity protein dishevelled homolog | 0.001 | 0.0164 | 0.0146 |
Entamoeba histolytica | Ras guanine nucleotide exchange factor, putative | 0.0007 | 0.0018 | 0.5 |
Entamoeba histolytica | Ras guanine nucleotide exchange factor, putative | 0.0007 | 0.0018 | 0.5 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.001 | 0.0164 | 0.048 |
Trichomonas vaginalis | ras GTP exchange factor, putative | 0.0007 | 0.0018 | 0.5 |
Entamoeba histolytica | Ras guanine nucleotide exchange factor, putative | 0.0007 | 0.0018 | 0.5 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.001 | 0.0164 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0164 | 0.0146 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0007 | 0.0018 | 0.0058 |
Schistosoma mansoni | dishevelled | 0.001 | 0.0164 | 0.0535 |
Entamoeba histolytica | Ras guanine nucleotide exchange factor, putative | 0.0007 | 0.0018 | 0.5 |
Schistosoma mansoni | regulator of G protein signaling | 0.001 | 0.0164 | 0.0535 |
Trichomonas vaginalis | ras GTP exchange factor, putative | 0.0007 | 0.0018 | 0.5 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.02 | 1 | 1 |
Entamoeba histolytica | Ras guanine nucleotide exchange factor, putative | 0.0007 | 0.0018 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.3065 | 1 |
Brugia malayi | hypothetical protein | 0.001 | 0.0164 | 0.0146 |
Schistosoma mansoni | ras GTP exchange factor | 0.0007 | 0.0018 | 0.0058 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.3065 | 1 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.001 | 0.0164 | 0.048 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.3065 | 1 |
Schistosoma mansoni | dishevelled | 0.001 | 0.0164 | 0.0535 |
Schistosoma mansoni | z-protein (S1r protein) | 0.001 | 0.0164 | 0.0535 |
Entamoeba histolytica | Ras guanine nucleotide exchange factor, putative | 0.0007 | 0.0018 | 0.5 |
Schistosoma mansoni | dep domain containing protein | 0.001 | 0.0164 | 0.0535 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.001 | 0.0164 | 0.048 |
Entamoeba histolytica | Ras guanine nucleotide exchange factor, putative | 0.0007 | 0.0018 | 0.5 |
Brugia malayi | RNA binding protein | 0.0066 | 0.3065 | 0.3053 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.001 | 0.0164 | 0.048 |
Brugia malayi | TAR-binding protein | 0.0066 | 0.3065 | 0.3053 |
Entamoeba histolytica | Ras guanine nucleotide exchange factor, putative | 0.0007 | 0.0018 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0066 | 0.3065 | 1 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.001 | 0.0164 | 0.048 |
Brugia malayi | DIX domain containing protein | 0.001 | 0.0164 | 0.0146 |
Entamoeba histolytica | Ras guanine nucleotide exchange factor, putative | 0.0007 | 0.0018 | 0.5 |
Entamoeba histolytica | Ras guanine nucleotide exchange factor, putative | 0.0007 | 0.0018 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0007 | 0.0018 | 0.5 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.001 | 0.0164 | 0.048 |
Toxoplasma gondii | hypothetical protein | 0.001 | 0.0164 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0164 | 0.0146 |
Entamoeba histolytica | Ras guanine nucleotide exchange factor, putative | 0.0007 | 0.0018 | 0.5 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.001 | 0.0164 | 0.0146 |
Trichomonas vaginalis | guanine nucleotide exchange factor, putative | 0.0007 | 0.0018 | 0.5 |
Trypanosoma cruzi | hypothetical protein | 0.0007 | 0.0018 | 0.5 |
Trypanosoma cruzi | hypothetical protein | 0.0007 | 0.0018 | 0.5 |
Onchocerca volvulus | 0.001 | 0.0164 | 0.0146 | |
Schistosoma mansoni | guanine-nucleotide-exchange-factor | 0.0007 | 0.0018 | 0.0058 |
Brugia malayi | hypothetical protein | 0.001 | 0.0164 | 0.0146 |
Trypanosoma cruzi | guanine nucleotide releasing protein, putative | 0.0007 | 0.0018 | 0.5 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.001 | 0.0164 | 0.0535 |
Echinococcus granulosus | tar DNA binding protein | 0.0066 | 0.3065 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0164 | 0.0146 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.