Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0083 | 0.0052 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.1071 | 0.2256 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0074 | 0.0788 | 0.1107 |
Echinococcus multilocularis | tar DNA binding protein | 0.0061 | 0.0624 | 0.0603 |
Brugia malayi | Pre-SET motif family protein | 0.0203 | 0.2522 | 0.2495 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0046 | 0.0421 | 0.0399 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.0083 | 0.006 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0167 | 0.2046 | 0.2017 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0023 | 0.0048 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0018 | 0.0036 | 0.0076 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0082 | 0.0903 | 0.303 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.0124 | 0.1012 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0018 | 0.0036 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0083 | 0.0052 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0021 | 0.0079 | 0.0166 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.0083 | 0.006 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0369 | 0.4747 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0061 | 0.0623 | 0.1313 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0037 | 0.0299 | 0.0631 |
Schistosoma mansoni | alpha-glucosidase | 0.0144 | 0.1733 | 0.3652 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0037 | 0.0295 | 0.026 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0018 | 0.0036 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0083 | 0.0052 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0018 | 0.0036 | 0.0076 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0095 | 0.1071 | 0.1044 |
Brugia malayi | mbt repeat family protein | 0.0046 | 0.0421 | 0.0386 |
Schistosoma mansoni | alpha-glucosidase | 0.0144 | 0.1733 | 0.3652 |
Echinococcus granulosus | muscleblind protein | 0.076 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.0083 | 0.0175 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0018 | 0.0037 | 0.0077 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0369 | 0.4747 | 1 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0369 | 0.4747 | 1 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0018 | 0.0036 | 0.0076 |
Giardia lamblia | Pyruvate kinase | 0.0037 | 0.0295 | 1 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0082 | 0.0903 | 1 |
Echinococcus multilocularis | thymidylate synthase | 0.0369 | 0.4747 | 0.4735 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0083 | 0.0052 |
Brugia malayi | RNA binding protein | 0.0061 | 0.0624 | 0.059 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0369 | 0.4747 | 1 |
Brugia malayi | TAR-binding protein | 0.0061 | 0.0624 | 0.059 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0203 | 0.2522 | 0.2499 |
Echinococcus multilocularis | muscleblind protein | 0.076 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0083 | 0.006 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0167 | 0.2046 | 0.2022 |
Schistosoma mansoni | hypothetical protein | 0.0281 | 0.3567 | 0.7514 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0069 | 0.0039 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0021 | 0.0083 | 0.0052 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0182 | 0.2242 | 0.2224 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0037 | 0.0295 | 0.0904 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0037 | 0.0295 | 0.0549 |
Loa Loa (eye worm) | hypothetical protein | 0.0261 | 0.3301 | 0.328 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0083 | 0.0047 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0082 | 0.0903 | 0.1903 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0083 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0413 | 0.0383 |
Trypanosoma brucei | glucosidase, putative | 0.0037 | 0.0299 | 0.0631 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.0083 | 0.006 |
Echinococcus granulosus | tar DNA binding protein | 0.0061 | 0.0624 | 0.0603 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0369 | 0.4747 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0192 | 0.0169 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0299 | 0.0631 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0021 | 0.0083 | 0.0175 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.072 | 0.0691 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0046 | 0.0421 | 0.0399 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0024 | 0.0124 | 0.0101 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0094 | 0.0198 |
Onchocerca volvulus | 0.0369 | 0.4747 | 1 | |
Loa Loa (eye worm) | steroid hormone receptor | 0.0021 | 0.0083 | 0.0052 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0369 | 0.4747 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0061 | 0.0624 | 0.0595 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0053 | 0.0506 | 0.0472 |
Echinococcus granulosus | FTZ F1 alpha | 0.0021 | 0.0083 | 0.006 |
Loa Loa (eye worm) | thymidylate synthase | 0.0369 | 0.4747 | 0.4731 |
Schistosoma mansoni | pyruvate kinase | 0.0037 | 0.0295 | 0.0621 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0083 | 0.0047 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0018 | 0.0036 | 0.0076 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0177 | 0.0155 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0506 | 0.0477 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0083 | 0.0052 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0624 | 0.1315 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0355 | 0.0325 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0175 | 0.2154 | 0.7401 |
Schistosoma mansoni | alpha glucosidase | 0.0037 | 0.0299 | 0.0631 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0037 | 0.0299 | 0.0264 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0083 | 0.0052 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0182 | 0.2242 | 0.2224 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0037 | 0.0295 | 0.0621 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0023 | 0.0048 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0024 | 0.0124 | 0.0088 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0018 | 0.0036 | 0.0076 |
Chlamydia trachomatis | pyruvate kinase | 0.0037 | 0.0295 | 0.5 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0037 | 0.0295 | 0.0454 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0421 | 0.0391 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0624 | 0.1315 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0082 | 0.0903 | 0.1903 |
Echinococcus granulosus | pyruvate kinase | 0.0019 | 0.0055 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.076 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0146 | 0.0115 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0299 | 0.092 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0083 | 0.0047 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.1071 | 0.1051 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0268 | 0.0246 |
Echinococcus multilocularis | pyruvate kinase | 0.0029 | 0.0191 | 0.0169 |
Loa Loa (eye worm) | TAR-binding protein | 0.0061 | 0.0624 | 0.0595 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0018 | 0.0036 | 0.0013 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0268 | 0.0246 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0624 | 0.1315 |
Onchocerca volvulus | 0.0097 | 0.11 | 0.218 | |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.0083 | 0.0047 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0053 | 0.0515 | 0.0481 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0021 | 0.0083 | 0.0047 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0299 | 0.0559 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0369 | 0.4747 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0083 | 0.0052 |
Echinococcus multilocularis | pyruvate kinase | 0.0019 | 0.0055 | 0.0032 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0369 | 0.4747 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0083 | 0.0052 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0061 | 0.0624 | 0.0595 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0037 | 0.0295 | 0.0454 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0018 | 0.0036 | 0.0013 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0046 | 0.0421 | 0.0391 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0058 | 0.0577 | 0.0555 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0053 | 0.0506 | 0.0485 |
Echinococcus multilocularis | zinc finger protein | 0.0019 | 0.0056 | 0.0033 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0018 | 0.0036 | 0.0076 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0053 | 0.0506 | 0.0485 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0046 | 0.0421 | 0.0399 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0167 | 0.2046 | 0.2028 |
Echinococcus multilocularis | pyruvate kinase | 0.0037 | 0.0295 | 0.0273 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0018 | 0.0036 | 0.0076 |
Echinococcus granulosus | serine protein kinase ATM | 0.0024 | 0.0124 | 0.0101 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0018 | 0.0036 | 0.0013 |
Schistosoma mansoni | coup transcription factor | 0.0021 | 0.0083 | 0.0175 |
Echinococcus granulosus | zinc finger protein | 0.0019 | 0.0056 | 0.0033 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0299 | 0.0631 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0082 | 0.0903 | 0.5 |
Echinococcus granulosus | pyruvate kinase | 0.0019 | 0.0055 | 0.0032 |
Mycobacterium ulcerans | thymidylate synthase | 0.0369 | 0.4747 | 1 |
Loa Loa (eye worm) | pyruvate kinase | 0.0037 | 0.0295 | 0.0265 |
Brugia malayi | ecdysteroid receptor | 0.0021 | 0.0083 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.03 | 0.027 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0046 | 0.0421 | 0.0886 |
Schistosoma mansoni | pyruvate kinase | 0.0019 | 0.0055 | 0.0115 |
Loa Loa (eye worm) | pyruvate kinase | 0.0037 | 0.0295 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0295 | 0.0265 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.0083 | 0.006 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.1071 | 0.1051 |
Giardia lamblia | Pyruvate kinase | 0.0019 | 0.0055 | 0.0716 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0299 | 0.092 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0083 | 0.0052 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0061 | 0.0624 | 0.059 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0074 | 0.0788 | 0.1107 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0192 | 0.0404 |
Brugia malayi | thymidylate synthase | 0.0369 | 0.4747 | 0.4728 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0082 | 0.0903 | 0.1841 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0624 | 0.1315 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0192 | 0.0156 |
Onchocerca volvulus | 0.0231 | 0.2898 | 0.6036 | |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0037 | 0.0295 | 0.0454 |
Brugia malayi | steroid hormone receptor | 0.0021 | 0.0083 | 0.0047 |
Leishmania major | pyruvate kinase | 0.0037 | 0.0295 | 0.0621 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.0299 | 0.0263 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.0083 | 0.0047 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0037 | 0.0295 | 0.0621 |
Loa Loa (eye worm) | MBCTL1 | 0.0053 | 0.0506 | 0.0477 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0299 | 0.092 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0037 | 0.0299 | 0.0277 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0024 | 0.0124 | 0.0261 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.1071 | 0.1051 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0083 | 0.0047 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0021 | 0.0083 | 0.006 |
Echinococcus multilocularis | pyruvate kinase | 0.0019 | 0.0055 | 0.0032 |
Plasmodium falciparum | pyruvate kinase | 0.0037 | 0.0295 | 0.0512 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0082 | 0.0903 | 0.1366 |
Echinococcus granulosus | pyruvate kinase | 0.0019 | 0.0055 | 0.0032 |
Echinococcus multilocularis | pyruvate kinase | 0.0019 | 0.0055 | 0.0032 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0167 | 0.2046 | 0.2028 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.0083 | 0.0047 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0082 | 0.0903 | 0.0882 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0299 | 0.092 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0046 | 0.0413 | 0.087 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.0083 | 0.006 |
Brugia malayi | nuclear hormone receptor | 0.0021 | 0.0083 | 0.0047 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0037 | 0.0299 | 0.092 |
Loa Loa (eye worm) | inositol-1 | 0.0082 | 0.0903 | 0.0875 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0175 | 0.2154 | 0.4538 |
Schistosoma mansoni | pyruvate kinase | 0.0037 | 0.0295 | 0.0621 |
Echinococcus multilocularis | pyruvate kinase | 0.0037 | 0.0295 | 0.0273 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0079 | 0.0048 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0037 | 0.0295 | 0.0621 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0046 | 0.0413 | 0.0391 |
Brugia malayi | Inositol-1 | 0.0082 | 0.0903 | 0.087 |
Brugia malayi | nuclear receptor NHR-88 | 0.0021 | 0.0083 | 0.0047 |
Brugia malayi | hypothetical protein | 0.0261 | 0.3301 | 0.3276 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0056 | 0.0117 |
Echinococcus granulosus | pyruvate kinase | 0.0037 | 0.0295 | 0.0273 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.033 | 0.0301 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.0083 | 0.0175 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0021 | 0.0083 | 0.006 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.0018 | 0.0036 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0083 | 0.0052 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0021 | 0.0083 | 0.0175 |
Loa Loa (eye worm) | pyruvate kinase | 0.0037 | 0.0295 | 0.0265 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0021 | 0.0083 | 0.0175 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0021 | 0.0083 | 0.0175 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0026 | 0.0146 | 0.0115 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0046 | 0.0413 | 0.0391 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0299 | 0.092 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0094 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0083 | 0.0052 |
Schistosoma mansoni | survival motor neuron protein | 0.0053 | 0.0515 | 0.1085 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0069 | 0.0146 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0083 | 0.0047 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0369 | 0.4747 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.076 | 1 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0192 | 0.033 |
Plasmodium vivax | pyruvate kinase, putative | 0.0037 | 0.0295 | 0.0512 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0083 | 0.0052 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0083 | 0.0052 |
Schistosoma mansoni | inositol monophosphatase | 0.0082 | 0.0903 | 0.1903 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0083 | 0.006 |
Brugia malayi | Bromodomain containing protein | 0.0073 | 0.0775 | 0.0742 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0018 | 0.0036 | 0.0076 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0021 | 0.0083 | 0.006 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0021 | 0.0083 | 0.0175 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0094 | 0.0071 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0261 | 0.3301 | 0.3285 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0053 | 0.0506 | 0.0485 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0082 | 0.0903 | 0.1903 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0095 | 0.1071 | 0.1039 |
Trypanosoma brucei | phosphatidylinositol kinase related protein, putative | 0.0024 | 0.0124 | 0.0261 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0058 | 0.0577 | 0.0555 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0037 | 0.0299 | 0.092 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0299 | 0.3036 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0046 | 0.0421 | 0.0886 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0082 | 0.0903 | 0.303 |
Echinococcus granulosus | thymidylate synthase | 0.0369 | 0.4747 | 0.4735 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0024 | 0.0124 | 0.0261 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0018 | 0.0036 | 0.0013 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0021 | 0.0083 | 0.006 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0021 | 0.0083 | 0.006 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0021 | 0.0083 | 0.006 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0037 | 0.0295 | 0.0904 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0021 | 0.0083 | 0.006 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0175 | 0.2154 | 0.4176 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0037 | 0.0295 | 0.0621 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.1071 | 0.2256 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0021 | 0.0083 | 0.0047 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0018 | 0.0036 | 0.0076 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0037 | 0.0299 | 0.027 |
Leishmania major | phosphatidylinositol kinase related protein, putative | 0.0018 | 0.0037 | 0.0077 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0261 | 0.3301 | 0.3285 |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.0083 | 0.0175 |
Toxoplasma gondii | pyruvate kinase PyKII | 0.0019 | 0.0055 | 0.0039 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0083 | 0.0047 |
Entamoeba histolytica | pyruvate kinase, putative | 0.0026 | 0.0146 | 0.1262 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0053 | 0.0506 | 0.1067 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0046 | 0.0421 | 0.0724 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0082 | 0.0903 | 0.1903 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0083 | 0.006 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0192 | 0.0404 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0018 | 0.0036 | 0.0076 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0083 | 0.0047 |
Echinococcus granulosus | pyruvate kinase | 0.0037 | 0.0295 | 0.0273 |
Trichomonas vaginalis | set domain proteins, putative | 0.0231 | 0.2898 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0021 | 0.0083 | 0.0175 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0018 | 0.0036 | 0.0076 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.1071 | 0.1051 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0046 | 0.0413 | 0.087 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0082 | 0.0903 | 0.303 |
Onchocerca volvulus | 0.0029 | 0.0192 | 0.0233 | |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0082 | 0.0903 | 0.0882 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.1071 | 0.2256 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0083 | 0.0047 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0299 | 0.092 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0299 | 0.3036 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0167 | 0.2046 | 0.2028 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0624 | 0.1315 |
Brugia malayi | PHD-finger family protein | 0.0024 | 0.0125 | 0.0089 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0299 | 0.092 |
Loa Loa (eye worm) | hypothetical protein | 0.076 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.0083 | 0.0175 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0037 | 0.0299 | 0.0277 |
Brugia malayi | mbt repeat family protein | 0.0046 | 0.0421 | 0.0386 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0083 | 0.0047 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0046 | 0.0421 | 0.0399 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0083 | 0.0047 |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.0515 | 0.1085 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0192 | 0.0292 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0021 | 0.0083 | 0.0175 |
Toxoplasma gondii | FATC domain-containing protein | 0.0024 | 0.0124 | 0.0186 |
Leishmania major | pyruvate kinase | 0.0037 | 0.0295 | 0.0621 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0018 | 0.0036 | 0.0076 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0124 | 0.0307 |
Onchocerca volvulus | 0.0046 | 0.0421 | 0.0724 | |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0037 | 0.0295 | 0.026 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0021 | 0.0083 | 0.0175 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0018 | 0.0036 | 0.0076 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.0083 | 0.006 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0046 | 0.0421 | 0.0886 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0053 | 0.0506 | 0.0485 |
Brugia malayi | hypothetical protein | 0.0175 | 0.2154 | 0.2126 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0018 | 0.0036 | 0.0005 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0018 | 0.0036 | 0.0076 |
Schistosoma mansoni | inositol monophosphatase | 0.0082 | 0.0903 | 0.1903 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0021 | 0.0083 | 0.0047 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0083 | 0.0052 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0018 | 0.0036 | 0.0076 |
Onchocerca volvulus | 0.0053 | 0.0515 | 0.0926 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.