Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | aldehyde dehydrogenase | 0.0068 | 0.3376 | 0.7275 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0105 | 0.5795 | 0.8841 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0021 | 0.032 | 0.0652 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0057 | 0.2652 | 0.3151 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0021 | 0.032 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0105 | 0.5795 | 0.8841 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0038 | 0.1428 | 0.2178 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0057 | 0.2692 | 0.2692 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0145 | 0.0172 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0053 | 0.2444 | 0.5265 |
Echinococcus multilocularis | geminin | 0.017 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.3645 | 0.3645 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.003 | 0.0933 | 0.1978 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.0839 | 0.1808 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.4641 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.0839 | 0.2485 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0016 | 0.0019 | 0.0041 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0023 | 0.0461 | 0.0993 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0046 | 0.197 | 0.3005 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0021 | 0.032 | 0.038 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0053 | 0.2444 | 0.3728 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0046 | 0.197 | 0.197 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0046 | 0.197 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0053 | 0.2444 | 0.7237 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0016 | 0.0019 | 0.0041 |
Loa Loa (eye worm) | glutathione reductase | 0.0046 | 0.197 | 0.2341 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0053 | 0.2444 | 0.5265 |
Brugia malayi | AMP-binding enzyme family protein | 0.0053 | 0.2444 | 0.2903 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0019 | 0.0096 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0145 | 0.0145 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0016 | 0.0019 | 0.0041 |
Onchocerca volvulus | 0.0081 | 0.4234 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0145 | 0.0145 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0021 | 0.032 | 0.1625 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0023 | 0.0461 | 0.0993 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0145 | 0.0172 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1569 | 0.1864 |
Echinococcus multilocularis | muscleblind protein | 0.0146 | 0.8416 | 0.8416 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0021 | 0.032 | 0.0488 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0038 | 0.1428 | 0.2178 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0016 | 0.0019 | 0.0019 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0021 | 0.032 | 0.0652 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0068 | 0.3376 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0046 | 0.197 | 0.4245 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0021 | 0.032 | 0.1625 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0029 | 0.0839 | 0.1808 |
Plasmodium falciparum | thioredoxin reductase | 0.0046 | 0.197 | 0.4245 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0053 | 0.2444 | 0.3728 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0839 | 0.4259 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0087 | 0.4641 | 0.4641 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0019 | 0.0096 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0016 | 0.0019 | 0.0041 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0053 | 0.2444 | 0.7237 |
Mycobacterium ulcerans | hypothetical protein | 0.0053 | 0.2444 | 0.5265 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0019 | 0.0096 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0072 | 0.3645 | 0.4331 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0839 | 0.0997 |
Loa Loa (eye worm) | TAR-binding protein | 0.0072 | 0.3645 | 0.4331 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0068 | 0.3376 | 0.5151 |
Echinococcus granulosus | tar DNA binding protein | 0.0072 | 0.3645 | 0.3645 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0087 | 0.4641 | 0.708 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0016 | 0.0019 | 0.0096 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0087 | 0.4641 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0016 | 0.0019 | 0.0096 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.004 | 0.1569 | 0.3381 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0053 | 0.2444 | 0.7237 |
Mycobacterium tuberculosis | Probable reductase | 0.0105 | 0.5795 | 0.8841 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0145 | 0.0145 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0016 | 0.0019 | 0.0041 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0038 | 0.1428 | 0.2178 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0053 | 0.2444 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.0145 | 0.0145 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.003 | 0.0933 | 0.2011 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0023 | 0.0461 | 0.0993 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1569 | 0.1864 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0068 | 0.3376 | 0.3376 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0839 | 0.1808 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0021 | 0.032 | 0.069 |
Brugia malayi | TAR-binding protein | 0.0072 | 0.3645 | 0.4331 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0839 | 0.1808 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0087 | 0.4641 | 0.4641 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0016 | 0.0019 | 0.0056 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.0839 | 0.4259 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0145 | 0.0145 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.4641 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.1492 | 0.1492 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0019 | 0.0096 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.032 | 0.069 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0839 | 0.0997 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0087 | 0.4641 | 0.4641 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0145 | 0.0172 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.2444 | 0.2903 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0057 | 0.2692 | 0.2692 |
Brugia malayi | Thioredoxin reductase | 0.0046 | 0.197 | 0.2341 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0016 | 0.0019 | 0.0041 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0021 | 0.032 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0145 | 0.0145 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0019 | 0.0056 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0021 | 0.032 | 0.032 |
Schistosoma mansoni | hypothetical protein | 0.017 | 1 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.0145 | 0.0145 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0053 | 0.2444 | 0.3728 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0039 | 0.1492 | 0.1772 |
Leishmania major | trypanothione reductase | 0.0046 | 0.197 | 0.5834 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0016 | 0.0019 | 0.0041 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0068 | 0.3376 | 0.3376 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.3645 | 0.3645 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0016 | 0.0019 | 0.0096 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.032 | 0.069 |
Onchocerca volvulus | 0.0053 | 0.2444 | 0.5771 | |
Toxoplasma gondii | hypothetical protein | 0.003 | 0.0933 | 0.2011 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0053 | 0.2444 | 1 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.4641 | 1 |
Plasmodium vivax | glutathione reductase, putative | 0.0046 | 0.197 | 0.4245 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.3645 | 0.3645 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.3645 | 0.3645 |
Brugia malayi | glutathione reductase | 0.0046 | 0.197 | 0.2341 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.4641 | 1 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0023 | 0.0461 | 0.0993 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0839 | 0.4259 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0046 | 0.197 | 0.197 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0068 | 0.3376 | 0.3376 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0081 | 0.4234 | 0.4234 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.004 | 0.1569 | 0.2394 |
Brugia malayi | Probable ClpP-like protease | 0.0087 | 0.4641 | 0.5514 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.004 | 0.1569 | 0.3354 |
Plasmodium falciparum | glutathione reductase | 0.0016 | 0.0019 | 0.0041 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0021 | 0.032 | 0.1625 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0019 | 0.0096 |
Plasmodium falciparum | thioredoxin reductase | 0.0016 | 0.0019 | 0.0041 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0057 | 0.2692 | 0.4107 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0087 | 0.4641 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0019 | 0.0096 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0021 | 0.032 | 1 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.003 | 0.0933 | 0.2011 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0019 | 0.0096 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.4641 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0145 | 0.0145 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0016 | 0.0019 | 0.0591 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0053 | 0.2444 | 0.5265 |
Toxoplasma gondii | thioredoxin reductase | 0.0046 | 0.197 | 0.4245 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0016 | 0.0019 | 0.0041 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0023 | 0.0461 | 0.0703 |
Brugia malayi | AMP-binding enzyme family protein | 0.0053 | 0.2444 | 0.2903 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.2652 | 0.3151 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0046 | 0.197 | 0.4245 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0105 | 0.5795 | 0.8841 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0046 | 0.197 | 0.2341 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1492 | 0.1772 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.003 | 0.0933 | 0.1424 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0021 | 0.032 | 0.131 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0016 | 0.0019 | 0.0591 |
Echinococcus granulosus | muscleblind protein | 0.0146 | 0.8416 | 0.8416 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.8416 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0146 | 0.8416 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0146 | 0.8416 | 0.8416 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0145 | 0.0172 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0016 | 0.0019 | 0.0029 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0019 | 0.0096 |
Brugia malayi | AMP-binding enzyme family protein | 0.0053 | 0.2444 | 0.2903 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.2444 | 0.2903 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.032 | 0.032 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0023 | 0.0461 | 0.0956 |
Trypanosoma brucei | trypanothione reductase | 0.0046 | 0.197 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0053 | 0.2444 | 0.5265 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0057 | 0.2692 | 0.4107 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0019 | 0.0096 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0117 | 0.6555 | 1 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0023 | 0.0461 | 0.1365 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0182 | 0.0216 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0068 | 0.3376 | 0.7275 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.4641 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.2444 | 0.2903 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0021 | 0.032 | 0.032 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0105 | 0.5795 | 0.8841 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0068 | 0.3376 | 0.7275 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1569 | 0.1864 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.3645 | 0.3645 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0057 | 0.2652 | 0.3151 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0057 | 0.2652 | 0.3151 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0053 | 0.2444 | 0.5265 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0021 | 0.032 | 0.038 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0023 | 0.0461 | 0.0993 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0068 | 0.3376 | 0.3376 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0145 | 0.0145 |
Toxoplasma gondii | exonuclease III APE | 0.0021 | 0.032 | 0.069 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0081 | 0.4234 | 0.4234 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0087 | 0.4641 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0038 | 0.1428 | 0.2178 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0053 | 0.2444 | 1 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0021 | 0.032 | 0.0948 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0053 | 0.2444 | 0.3728 |
Mycobacterium leprae | conserved hypothetical protein | 0.0023 | 0.0461 | 0.0703 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0023 | 0.0461 | 0.0993 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0081 | 0.4234 | 0.4234 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0461 | 0.1886 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0016 | 0.0019 | 0.0056 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0019 | 0.0096 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0117 | 0.6555 | 1 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0016 | 0.0019 | 0.0022 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0016 | 0.0019 | 0.0019 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0145 | 0.0145 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.032 | 0.032 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0016 | 0.0019 | 0.0041 |
Brugia malayi | RNA binding protein | 0.0072 | 0.3645 | 0.4331 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.8416 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0072 | 0.3645 | 0.4331 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1569 | 0.1864 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0081 | 0.4234 | 0.5031 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.4234 | 0.5031 |
Echinococcus multilocularis | tar DNA binding protein | 0.0072 | 0.3645 | 0.3645 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0016 | 0.0019 | 0.0019 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.0023 | 0.0461 | 0.0956 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0072 | 0.3645 | 0.4331 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.004 | 0.1569 | 0.3381 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0019 | 0.0056 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0057 | 0.2692 | 0.4107 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0023 | 0.0461 | 0.0956 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0105 | 0.5795 | 0.8841 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0117 | 0.6555 | 1 |
Plasmodium falciparum | acyl-CoA synthetase | 0.004 | 0.1569 | 0.3381 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1569 | 0.1864 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0105 | 0.5795 | 0.8841 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0117 | 0.6555 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0053 | 0.2444 | 0.5265 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.4641 | 0.5514 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0023 | 0.0461 | 0.2339 |
Schistosoma mansoni | hypothetical protein | 0.017 | 1 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0053 | 0.2444 | 0.5265 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0068 | 0.3376 | 0.7275 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0087 | 0.4641 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.