Detailed information for compound 704329

Basic information

Technical information
  • TDR Targets ID: 704329
  • Name: N-(6-acetamido-1,3-benzothiazol-2-yl)-3-(4-fl uorophenyl)sulfanylpropanamide
  • MW: 389.467 | Formula: C18H16FN3O2S2
  • H donors: 2 H acceptors: 3 LogP: 3.31 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1nc2c(s1)cc(cc2)NC(=O)C)CCSc1ccc(cc1)F
  • InChi: 1S/C18H16FN3O2S2/c1-11(23)20-13-4-7-15-16(10-13)26-18(21-15)22-17(24)8-9-25-14-5-2-12(19)3-6-14/h2-7,10H,8-9H2,1H3,(H,20,23)(H,21,22,24)
  • InChiKey: SGOAODZOXZGACY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(6-acetamido-1,3-benzothiazol-2-yl)-3-(4-fluorophenyl)sulfanyl-propanamide
  • N-(6-acetamido-1,3-benzothiazol-2-yl)-3-[(4-fluorophenyl)thio]propanamide
  • N-(6-acetamido-1,3-benzothiazol-2-yl)-3-[(4-fluorophenyl)thio]propionamide
  • ZINC04496816

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0157 0.5999 0.5999
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0214 0.0214
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0095 0.5
Brugia malayi beta-lactamase family protein 0.0035 0.0832 0.0832
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.0023 0.0342 0.0342
Mycobacterium tuberculosis Conserved protein 0.0035 0.0832 0.0895
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.6343 0.6011
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0832 0.0895
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.6719 0.6421
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0342 0.2885
Mycobacterium ulcerans hypothetical protein 0.0035 0.0832 0.8608
Echinococcus multilocularis zinc finger protein 0.0041 0.108 0.1315
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0136 0.5112 0.5112
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0075 0.2512 0.3488
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0214 0.0214
Trichomonas vaginalis glucosylceramidase, putative 0.0252 1 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0951 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0342 0.033
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.055 0.055
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0342 0.2885
Schistosoma mansoni alpha glucosidase 0.0035 0.0838 0.0947
Onchocerca volvulus Huntingtin homolog 0.0124 0.4599 0.7154
Echinococcus granulosus fetal alzheimer antigen falz 0.0047 0.134 0.1709
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.6343 0.6011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0214 0.0214
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0951 0.1119
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0342 0.0342
Leishmania major hypothetical protein, conserved 0.0035 0.0832 0.8044
Onchocerca volvulus 0.0035 0.0832 0.1008
Brugia malayi nuclear hormone receptor 0.002 0.0214 0.0214
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0832 0.0895
Mycobacterium leprae Probable lipase LipE 0.0035 0.0832 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0214 0.0214
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0838 0.8143
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0951 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0951 0.5
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0859 0.098
Loa Loa (eye worm) hypothetical protein 0.008 0.2726 0.2726
Echinococcus multilocularis GPCR, family 2 0.0031 0.0659 0.0676
Onchocerca volvulus 0.0091 0.3202 0.4876
Loa Loa (eye worm) hypothetical protein 0.0124 0.4599 0.4599
Schistosoma mansoni hypothetical protein 0.0043 0.1173 0.1455
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.0035 0.0832 0.0832
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0951 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0214 0.0214
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0214 0.0214
Echinococcus granulosus geminin 0.0176 0.6803 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0124 0.4594 0.6647
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0838 0.8143
Brugia malayi beta-lactamase family protein 0.0035 0.0832 0.0832
Loa Loa (eye worm) bromodomain containing protein 0.0037 0.0913 0.0913
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0222 0.8731 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0342 0.2885
Onchocerca volvulus 0.0028 0.055 0.0548
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0832 0.0938
Echinococcus multilocularis lamin dm0 0.0028 0.055 0.051
Mycobacterium ulcerans hypothetical protein 0.0023 0.0342 0.2885
Trichomonas vaginalis glucosylceramidase, putative 0.0252 1 1
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.6343 0.6011
Echinococcus granulosus lamin 0.0028 0.055 0.051
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0838 0.0007
Echinococcus multilocularis geminin 0.0176 0.6803 1
Brugia malayi hypothetical protein 0.0124 0.4599 0.4599
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0214 0.0214
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0075 0.2512 0.3488
Echinococcus granulosus methyl CpG binding domain protein 2 0.0035 0.0859 0.098
Loa Loa (eye worm) hypothetical protein 0.0035 0.0832 0.0832
Schistosoma mansoni bromodomain containing protein 0.0131 0.4907 0.7123
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.6343 0.6011
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0659 0.0659
Trypanosoma brucei glucosidase, putative 0.0035 0.0838 0.5392
Brugia malayi Bromodomain containing protein 0.008 0.272 0.272
Echinococcus granulosus zinc finger protein 0.0041 0.108 0.1315
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0838 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0214 0.0214
Loa Loa (eye worm) intermediate filament protein 0.0028 0.055 0.055
Echinococcus multilocularis lysosomal alpha glucosidase 0.0157 0.5999 0.878
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0832 0.5146
Loa Loa (eye worm) hypothetical protein 0.002 0.0214 0.0214
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0832 1
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0342 0.2885
Loa Loa (eye worm) hypothetical protein 0.0089 0.3101 0.3101
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0214 0.0214
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0951 0.1032
Loa Loa (eye worm) hypothetical protein 0.0017 0.0095 0.0095
Schistosoma mansoni hypothetical protein 0.0032 0.0706 0.0746
Onchocerca volvulus 0.0028 0.055 0.0548
Echinococcus multilocularis musashi 0.0028 0.055 0.051
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.5112 0.7434
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0832 0.0938
Echinococcus granulosus GPCR family 2 0.0031 0.0659 0.0676
Schistosoma mansoni alpha-glucosidase 0.0135 0.5076 0.7378
Brugia malayi steroid hormone receptor 0.002 0.0214 0.0214
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0832 0.0895
Onchocerca volvulus Huntingtin homolog 0.0124 0.4599 0.7154
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0214 0.0214
Mycobacterium tuberculosis Conserved protein 0.0035 0.0832 0.0895
Onchocerca volvulus 0.0035 0.0832 0.1008
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0136 0.5112 0.5112
Loa Loa (eye worm) hypothetical protein 0.002 0.0214 0.0214
Schistosoma mansoni zinc finger protein 0.0041 0.108 0.1315
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0951 0.5
Loa Loa (eye worm) hypothetical protein 0.0035 0.0859 0.0859
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0214 0.0214
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0214 0.0214
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0035 0.0859 0.098
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0832 0.5146
Loa Loa (eye worm) hypothetical protein 0.0028 0.0528 0.0528
Onchocerca volvulus 0.0035 0.0832 0.1008
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0832 0.8608
Loa Loa (eye worm) hypothetical protein 0.002 0.0214 0.0214
Schistosoma mansoni hypothetical protein 0.0066 0.2159 0.2953
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0342 0.0342
Schistosoma mansoni zinc finger protein 0.0032 0.0706 0.0746
Brugia malayi Glycosyl hydrolases family 31 protein 0.0157 0.5999 0.5999
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0214 0.0214
Brugia malayi Calcitonin receptor-like protein seb-1 0.0097 0.3452 0.3452
Loa Loa (eye worm) hypothetical protein 0.0023 0.0342 0.0342
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0832 0.0895
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0124 0.4594 0.6647
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0214 0.0214
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0951 0.0951
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0838 0.0007
Onchocerca volvulus 0.0023 0.0342 0.0209
Loa Loa (eye worm) hypothetical protein 0.0066 0.2159 0.2159
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0951 0.013
Schistosoma mansoni hypothetical protein 0.0176 0.6803 1
Echinococcus granulosus lamin dm0 0.0028 0.055 0.051
Loa Loa (eye worm) hypothetical protein 0.0085 0.2933 0.2933
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.6343 0.6011
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0252 1 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0342 0.0342
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0859 0.098
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0097 0.3452 0.3452
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0832 0.0832
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0214 0.0214
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0838 0.0507
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0832 0.8608
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.6343 0.6011
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0659 0.0676
Loa Loa (eye worm) hypothetical protein 0.0035 0.0832 0.0832
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0342 0.033
Leishmania major hypothetical protein, conserved 0.0032 0.0706 0.5971
Toxoplasma gondii exonuclease III APE 0.0038 0.0951 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0659 0.0676
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0951 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0859 0.098
Loa Loa (eye worm) hypothetical protein 0.0017 0.0095 0.0095
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0838 0.0007
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0659 0.0676
Brugia malayi PHD-finger family protein 0.0052 0.1547 0.1547
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0832 0.0938
Schistosoma mansoni alpha-glucosidase 0.0135 0.5076 0.7378
Loa Loa (eye worm) hypothetical protein 0.002 0.0214 0.0214
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.5112 0.7434
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0214 0.0214
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0859 0.098
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0832 0.0895
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0951 0.0951
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0838 0.8143
Echinococcus granulosus intermediate filament protein 0.0028 0.055 0.051
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0214 0.0214
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0095 0.0046
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0951 1
Loa Loa (eye worm) hypothetical protein 0.0124 0.4599 0.4599
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0047 0.134 0.1709
Loa Loa (eye worm) beta-lactamase 0.0035 0.0832 0.0832
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0214 0.0214
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0951 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0342 0.2885
Trichomonas vaginalis glucosylceramidase, putative 0.0252 1 1
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0838 0.0947
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.5112 0.7434
Loa Loa (eye worm) hypothetical protein 0.0097 0.3452 0.3452
Loa Loa (eye worm) hypothetical protein 0.0017 0.0095 0.0095
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0832 0.0832
Brugia malayi nuclear receptor NHR-88 0.002 0.0214 0.0214
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0214 0.0214
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.5112 0.7434
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0838 0.0838
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.5112 0.7434
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0951 0.013
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0951 1
Brugia malayi latrophilin 2 splice variant baaae 0.0066 0.2159 0.2159
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0951 0.5
Loa Loa (eye worm) hypothetical protein 0.0035 0.0832 0.0832
Loa Loa (eye worm) hypothetical protein 0.0035 0.0832 0.0832
Brugia malayi beta-lactamase 0.0035 0.0832 0.0832
Loa Loa (eye worm) hypothetical protein 0.0147 0.5559 0.5559
Loa Loa (eye worm) hypothetical protein 0.0028 0.055 0.055
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0659 0.0676
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0832 0.5146
Schistosoma mansoni hypothetical protein 0.0031 0.0659 0.0676
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0838 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0252 1 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0659 0.0659
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0832 0.0895
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0659 0.0659
Loa Loa (eye worm) PHD-finger family protein 0.0043 0.1173 0.1173
Schistosoma mansoni hypothetical protein 0.0031 0.0659 0.0676
Echinococcus multilocularis lysosomal alpha glucosidase 0.0157 0.5999 0.878
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0859 0.098
Loa Loa (eye worm) hypothetical protein 0.002 0.0214 0.0214
Brugia malayi Bromodomain containing protein 0.0156 0.5933 0.5933
Schistosoma mansoni hypothetical protein 0.0176 0.6803 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0838 0.0007
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0951 1
Brugia malayi intermediate filament protein 0.0028 0.055 0.055
Echinococcus multilocularis lamin 0.0028 0.055 0.051
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.6719 0.6421
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0097 0.3452 0.3452
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0342 0.2885
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0214 0.0214
Trichomonas vaginalis glucosylceramidase, putative 0.0252 1 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0951 0.1119
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.055 0.055
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0859 0.098
Loa Loa (eye worm) hypothetical protein 0.0035 0.0832 0.0832
Schistosoma mansoni ap endonuclease 0.0038 0.0951 0.1119
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0838 0.0007
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0838 0.0947
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0838 0.5392
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.5112 0.7434
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0832 0.8608
Mycobacterium tuberculosis Conserved protein 0.0035 0.0832 0.0895
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0838 0.0007
Schistosoma mansoni lamin 0.0028 0.055 0.051
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.6343 0.6011
Brugia malayi ecdysteroid receptor 0.002 0.0214 0.0214
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0342 0.0342
Mycobacterium ulcerans lipase LipD 0.0035 0.0832 0.8608
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0838 0.0007
Schistosoma mansoni lamin 0.0028 0.055 0.051
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0214 0.0214
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0838 0.5392
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.002 0.0214 0.0214
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0832 0.0938
Trichomonas vaginalis glucosylceramidase, putative 0.0252 1 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0342 0.2885
Loa Loa (eye worm) hypothetical protein 0.002 0.0214 0.0214
Onchocerca volvulus Glucosylceramidase homolog 0.0166 0.6343 1
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.0017 0.0095 0.0095
Schistosoma mansoni intermediate filament proteins 0.0028 0.055 0.051
Echinococcus granulosus lysosomal alpha glucosidase 0.0157 0.5999 0.878
Schistosoma mansoni hypothetical protein 0.0031 0.0659 0.0676
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0838 0.0838
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.5112 0.7434
Loa Loa (eye worm) hypothetical protein 0.0031 0.0659 0.0659
Loa Loa (eye worm) hypothetical protein 0.0017 0.0095 0.0095
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0832 0.0895
Schistosoma mansoni hypothetical protein 0.0031 0.0659 0.0676
Mycobacterium ulcerans beta-lactamase 0.0035 0.0832 0.8608
Schistosoma mansoni ap endonuclease 0.0038 0.0951 0.1119
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0047 0.134 0.1709

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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