Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | beta-lactamase | 0.0072 | 0.0732 | 0.1562 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.003 | 0.0231 | 0.0231 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0088 | 0.0923 | 0.167 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0047 | 0.0431 | 0.1544 |
Schistosoma mansoni | hypothetical protein | 0.0128 | 0.1394 | 0.1397 |
Trichomonas vaginalis | esterase, putative | 0.0072 | 0.0732 | 0.2623 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0283 | 0.3239 | 0.4621 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0732 | 0.1007 |
Loa Loa (eye worm) | TAR-binding protein | 0.026 | 0.2963 | 0.4076 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0155 | 0.1716 | 1 |
Brugia malayi | glutathione reductase | 0.0039 | 0.0331 | 0.0706 |
Plasmodium falciparum | zinc finger protein, putative | 0.0014 | 0.0034 | 0.0201 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0013 | 0.0029 | 0.0169 |
Echinococcus multilocularis | tar DNA binding protein | 0.026 | 0.2963 | 0.2963 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0404 | 0.4688 | 0.6447 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0027 | 0.0187 | 0.067 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0033 | 0.0264 | 0.0265 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0016 | 0.0058 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0039 | 0.0331 | 0.0455 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0013 | 0.0029 | 0.0104 |
Schistosoma mansoni | smad | 0.0016 | 0.0065 | 0.0065 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0072 | 0.0732 | 0.1958 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0027 | 0.0187 | 0.067 |
Echinococcus granulosus | importin subunit beta 1 | 0.0058 | 0.0562 | 0.0564 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0621 | 0.7271 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0128 | 0.1394 | 0.2973 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.003 | 0.0231 | 0.0232 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0098 | 0.1041 | 0.1889 |
Schistosoma mansoni | hypothetical protein | 0.0128 | 0.1394 | 0.1397 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.022 | 0.0221 |
Brugia malayi | CXXC zinc finger family protein | 0.0118 | 0.1273 | 0.2715 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0432 | 0.0433 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0013 | 0.0029 | 0.0029 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0432 | 0.0433 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0013 | 0.0029 | 0.0042 |
Schistosoma mansoni | hypothetical protein | 0.0621 | 0.7271 | 0.729 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0667 | 0.7813 | 0.7834 |
Plasmodium vivax | SET domain protein, putative | 0.0033 | 0.0264 | 0.1539 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0404 | 0.4688 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0013 | 0.0029 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0584 | 0.0803 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0732 | 0.1313 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.1394 | 0.1917 |
Toxoplasma gondii | thioredoxin reductase | 0.0039 | 0.0331 | 0.1303 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0088 | 0.0923 | 0.167 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0016 | 0.0065 | 0.0089 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.0109 | 1 |
Schistosoma mansoni | ran | 0.0043 | 0.0379 | 0.038 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0016 | 0.0065 | 0.0065 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0013 | 0.0029 | 0.0018 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0016 | 0.0058 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0598 | 0.699 | 1 |
Entamoeba histolytica | Ran family GTPase | 0.0043 | 0.0379 | 0.5001 |
Schistosoma mansoni | ran | 0.0043 | 0.0379 | 0.038 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0033 | 0.0264 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0732 | 0.1007 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0732 | 0.1007 |
Schistosoma mansoni | tar DNA-binding protein | 0.026 | 0.2963 | 0.2971 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0128 | 0.1394 | 0.1397 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0014 | 0.004 | 0.0142 |
Echinococcus granulosus | tar DNA binding protein | 0.026 | 0.2963 | 0.2971 |
Brugia malayi | Thioredoxin reductase | 0.0039 | 0.0331 | 0.0706 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0016 | 0.0065 | 0.0065 |
Echinococcus granulosus | smad | 0.0016 | 0.0065 | 0.0065 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0.0109 | 0.0157 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0432 | 0.0433 |
Brugia malayi | hypothetical protein | 0.0155 | 0.1716 | 0.366 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0155 | 0.1716 | 0.2437 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0128 | 0.1394 | 0.1917 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0038 | 0.0317 | 0.0317 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0241 | 0.2743 | 0.3773 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0084 | 0.087 | 0.1245 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.3163 | 0.435 |
Schistosoma mansoni | hypothetical protein | 0.0128 | 0.1394 | 0.1397 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0038 | 0.0317 | 0.0317 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0276 | 0.3163 | 0.6747 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0128 | 0.1394 | 0.1397 |
Schistosoma mansoni | hypothetical protein | 0.0848 | 0.9973 | 1 |
Echinococcus granulosus | snurportin 1 | 0.0621 | 0.7271 | 0.729 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0598 | 0.699 | 1 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0109 | 0.0157 |
Echinococcus multilocularis | snurportin 1 | 0.0621 | 0.7271 | 0.7271 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.0109 | 0.015 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0598 | 0.699 | 1 |
Brugia malayi | hypothetical protein | 0.0075 | 0.0758 | 0.1617 |
Leishmania major | hypothetical protein, conserved | 0.0155 | 0.1716 | 0.2454 |
Trypanosoma brucei | trypanothione reductase | 0.0039 | 0.0331 | 0.0474 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0013 | 0.0029 | 0.0042 |
Brugia malayi | TAR-binding protein | 0.026 | 0.2963 | 0.6321 |
Brugia malayi | Fli-1 protein | 0.0213 | 0.2409 | 0.5138 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0013 | 0.0029 | 0.0114 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0075 | 0.0758 | 0.076 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0013 | 0.0029 | 0.0018 |
Echinococcus multilocularis | tumor protein p63 | 0.069 | 0.8096 | 0.8096 |
Onchocerca volvulus | 0.0118 | 0.1273 | 0.3991 | |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0088 | 0.0923 | 0.167 |
Schistosoma mansoni | cpg binding protein | 0.0125 | 0.1353 | 0.1356 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0109 | 0.0638 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0109 | 0.0638 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0098 | 0.1041 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0109 | 0.0392 |
Brugia malayi | hypothetical protein | 0.01 | 0.1061 | 0.2264 |
Brugia malayi | beta-lactamase family protein | 0.0072 | 0.0732 | 0.1562 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0029 | 0.0018 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0187 | 0.067 |
Echinococcus granulosus | GPCR family 2 | 0.0128 | 0.1394 | 0.1397 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0463 | 0.5385 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0187 | 0.067 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0732 | 0.1027 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0027 | 0.0187 | 0.067 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0013 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0404 | 0.4688 | 0.6447 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0033 | 0.0264 | 0.0264 |
Loa Loa (eye worm) | beta-lactamase | 0.0072 | 0.0732 | 0.1007 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0264 | 0.0265 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0039 | 0.0331 | 0.0451 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0109 | 0.0109 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0241 | 0.2743 | 0.3773 |
Echinococcus multilocularis | cpg binding protein | 0.0125 | 0.1353 | 0.1353 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0013 | 0.0029 | 0.0042 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0264 | 0.0265 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0013 | 0.0029 | 0.0042 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0072 | 0.0732 | 0.0734 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0088 | 0.0923 | 0.167 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0072 | 0.0732 | 0.1007 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0072 | 0.0732 | 0.1313 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.002 | 0.0109 | 0.0224 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0189 | 0.2124 | 0.736 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.0109 | 0.015 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0072 | 0.0732 | 0.1313 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0667 | 0.7813 | 0.7813 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0732 | 0.1313 |
Onchocerca volvulus | 0.0072 | 0.0732 | 0.1852 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0432 | 0.0432 |
Echinococcus multilocularis | smad | 0.0016 | 0.0065 | 0.0065 |
Schistosoma mansoni | tar DNA-binding protein | 0.026 | 0.2963 | 0.2971 |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0.0109 | 0.043 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0043 | 0.0379 | 0.0542 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.002 | 0.0109 | 0.2296 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0013 | 0.0029 | 0.0062 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0732 | 0.2623 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0732 | 0.1007 |
Loa Loa (eye worm) | Smad1 | 0.0016 | 0.0065 | 0.0089 |
Entamoeba histolytica | hypothetical protein | 0.0047 | 0.0431 | 0.5686 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0016 | 0.0065 | 0.0065 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0732 | 0.2623 |
Brugia malayi | RNA binding protein | 0.026 | 0.2963 | 0.6321 |
Echinococcus granulosus | Smad4 | 0.0016 | 0.0065 | 0.0065 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0109 | 0.011 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0016 | 0.0065 | 0.0065 |
Leishmania major | hypothetical protein, conserved | 0.0072 | 0.0732 | 0.1047 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0072 | 0.0732 | 0.1313 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.003 | 0.0231 | 0.0232 |
Entamoeba histolytica | hypothetical protein | 0.0075 | 0.0758 | 1 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0029 | 0.0042 |
Entamoeba histolytica | hypothetical protein | 0.0014 | 0.0034 | 0.0455 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0029 | 0.0018 |
Schistosoma mansoni | tar DNA-binding protein | 0.026 | 0.2963 | 0.2971 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0029 | 0.0042 |
Trichomonas vaginalis | helicase, putative | 0.0027 | 0.0187 | 0.067 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0251 | 0.286 | 0.2868 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0098 | 0.1041 | 0.1889 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0128 | 0.1394 | 0.2973 |
Echinococcus multilocularis | Smad4 | 0.0016 | 0.0065 | 0.0065 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0029 | 0.0018 |
Brugia malayi | Ets-domain containing protein | 0.007 | 0.0705 | 0.1505 |
Schistosoma mansoni | Smad4 | 0.0016 | 0.0065 | 0.0065 |
Echinococcus multilocularis | GPCR, family 2 | 0.0128 | 0.1394 | 0.1394 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0072 | 0.0732 | 0.2623 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0043 | 0.0379 | 0.1492 |
Trichomonas vaginalis | set domain proteins, putative | 0.0245 | 0.2792 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0562 | 0.0773 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0848 | 0.9973 | 0.9973 |
Plasmodium vivax | importin-beta 2, putative | 0.0058 | 0.0562 | 0.3277 |
Schistosoma mansoni | myst-related protein | 0.0014 | 0.0034 | 0.0035 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.007 | 0.0705 | 0.0705 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0088 | 0.0923 | 0.167 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.0109 | 0.0134 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0013 | 0.0029 | 0.0042 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0128 | 0.1394 | 0.1394 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.1716 | 0.236 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0043 | 0.0379 | 0.0379 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0012 | 0.0016 | 0.0058 |
Plasmodium falciparum | importin beta, putative | 0.0058 | 0.0562 | 0.3277 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0432 | 0.0921 |
Brugia malayi | Smad1 | 0.0016 | 0.0065 | 0.0138 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0043 | 0.0379 | 0.221 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0432 | 0.0432 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0732 | 0.1027 |
Schistosoma mansoni | myst-related protein | 0.0014 | 0.0034 | 0.0035 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0014 | 0.004 | 0.0142 |
Trypanosoma brucei | ISWI complex protein | 0.0012 | 0.0016 | 0.0023 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0432 | 0.0433 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0075 | 0.0758 | 0.076 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0027 | 0.0187 | 0.067 |
Entamoeba histolytica | hypothetical protein | 0.0075 | 0.0758 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.003 | 0.0231 | 0.0232 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0084 | 0.087 | 0.1224 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0155 | 0.1716 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0072 | 0.0732 | 0.1958 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0072 | 0.0732 | 0.1313 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0027 | 0.0187 | 0.067 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0187 | 0.067 |
Mycobacterium ulcerans | hypothetical protein | 0.0315 | 0.362 | 1 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0013 | 0.0029 | 0.0114 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0065 | 0.0065 |
Brugia malayi | RNA, U transporter 1 | 0.0165 | 0.1841 | 0.3926 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0033 | 0.0264 | 0.1039 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0043 | 0.0379 | 0.038 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0109 | 0.011 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0155 | 0.1716 | 0.2454 |
Loa Loa (eye worm) | histone methyltransferase | 0.0038 | 0.0317 | 0.0435 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0187 | 0.067 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.0697 | 0.0699 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0732 | 0.1313 |
Plasmodium falciparum | glutathione reductase | 0.0013 | 0.0029 | 0.0169 |
Plasmodium falciparum | thioredoxin reductase | 0.0013 | 0.0029 | 0.0169 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0029 | 0.0018 |
Leishmania major | trypanothione reductase | 0.0039 | 0.0331 | 0.0474 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0667 | 0.7813 | 0.7834 |
Echinococcus granulosus | tumor protein p63 | 0.069 | 0.8096 | 0.8118 |
Leishmania major | importin beta-1 subunit, putative | 0.0047 | 0.0431 | 0.0617 |
Mycobacterium tuberculosis | Probable reductase | 0.0088 | 0.0923 | 0.167 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0072 | 0.0732 | 0.0732 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0187 | 0.067 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0029 | 0.0018 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0187 | 0.067 |
Schistosoma mansoni | cpg binding protein | 0.0118 | 0.1273 | 0.1276 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0224 | 0.2542 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0072 | 0.0732 | 0.288 |
Brugia malayi | Importin beta-1 subunit | 0.0058 | 0.0562 | 0.1199 |
Loa Loa (eye worm) | glutathione reductase | 0.0039 | 0.0331 | 0.0455 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0027 | 0.0187 | 0.067 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0039 | 0.0337 | 0.0338 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0732 | 0.1007 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0118 | 0.1273 | 0.1751 |
Mycobacterium ulcerans | beta-lactamase | 0.0072 | 0.0732 | 0.1958 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0732 | 0.1007 |
Schistosoma mansoni | hypothetical protein | 0.0276 | 0.3163 | 0.3172 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0013 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.007 | 0.0705 | 0.097 |
Onchocerca volvulus | 0.0072 | 0.0732 | 0.1852 | |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0039 | 0.0331 | 0.0564 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0058 | 0.0562 | 0.2212 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0155 | 0.1716 | 0.2437 |
Schistosoma mansoni | hypothetical protein | 0.0128 | 0.1394 | 0.1397 |
Brugia malayi | N-terminal motif family protein | 0.0189 | 0.2124 | 0.4532 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0404 | 0.4688 | 1 |
Schistosoma mansoni | gabp alpha | 0.007 | 0.0705 | 0.0707 |
Echinococcus multilocularis | geminin | 0.0188 | 0.2106 | 0.2106 |
Schistosoma mansoni | tar DNA-binding protein | 0.026 | 0.2963 | 0.2971 |
Mycobacterium ulcerans | lipase LipD | 0.0072 | 0.0732 | 0.1958 |
Entamoeba histolytica | hypothetical protein | 0.0075 | 0.0758 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0075 | 0.0758 | 0.076 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0264 | 0.0363 |
Onchocerca volvulus | 0.0072 | 0.0732 | 0.1852 | |
Plasmodium vivax | thioredoxin reductase, putative | 0.0039 | 0.0331 | 0.193 |
Plasmodium vivax | hypothetical protein, conserved | 0.0072 | 0.0732 | 0.4268 |
Loa Loa (eye worm) | fli-1 protein | 0.0213 | 0.2409 | 0.3313 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.0065 | 0.0138 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0027 | 0.0187 | 0.067 |
Loa Loa (eye worm) | hypothetical protein | 0.0189 | 0.2124 | 0.2922 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0109 | 0.0134 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0027 | 0.0187 | 0.067 |
Schistosoma mansoni | tar DNA-binding protein | 0.026 | 0.2963 | 0.2971 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0187 | 0.067 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0043 | 0.0379 | 0.052 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0102 | 0.1089 | 0.1539 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0084 | 0.087 | 0.1224 |
Brugia malayi | Pre-SET motif family protein | 0.0033 | 0.0264 | 0.0563 |
Trichomonas vaginalis | hypothetical protein | 0.0014 | 0.004 | 0.0142 |
Brugia malayi | Ets-domain containing protein | 0.007 | 0.0705 | 0.1505 |
Brugia malayi | beta-lactamase family protein | 0.0072 | 0.0732 | 0.1562 |
Leishmania major | GTP-binding protein, putative | 0.0043 | 0.0379 | 0.0542 |
Toxoplasma gondii | hypothetical protein | 0.0096 | 0.1017 | 0.4002 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0072 | 0.0732 | 0.1047 |
Brugia malayi | RNA recognition motif domain containing protein | 0.026 | 0.2963 | 0.6321 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0033 | 0.0264 | 0.0264 |
Brugia malayi | MH2 domain containing protein | 0.0241 | 0.2743 | 0.5851 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0072 | 0.0732 | 0.2623 |
Echinococcus granulosus | dnaJ subfamily B | 0.0848 | 0.9973 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0732 | 0.2623 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0128 | 0.1394 | 0.1394 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0058 | 0.0562 | 0.0804 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.007 | 0.0697 | 0.0699 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0155 | 0.1716 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0155 | 0.1716 | 0.6749 |
Schistosoma mansoni | ets-related | 0.0213 | 0.2409 | 0.2415 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0018 | 0.0084 | 0.0084 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0016 | 0.0065 | 0.0065 |
Onchocerca volvulus | 0.0101 | 0.1073 | 0.3201 | |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0047 | 0.0431 | 0.1544 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0264 | 0.0265 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0043 | 0.0379 | 0.0809 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.0065 | 0.0138 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.002 | 0.0109 | 0.1443 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0084 | 0.087 | 0.1224 |
Echinococcus granulosus | cpg binding protein | 0.0125 | 0.1353 | 0.1356 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.0065 | 0.0138 |
Loa Loa (eye worm) | RNA binding protein | 0.026 | 0.2963 | 0.4076 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0013 | 0.0029 | 0.0018 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0072 | 0.0732 | 0.0734 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0075 | 0.0758 | 0.0758 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0043 | 0.0379 | 0.052 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0058 | 0.0562 | 0.0804 |
Echinococcus granulosus | GA binding protein alpha chain | 0.007 | 0.0705 | 0.0707 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0432 | 0.0433 |
Schistosoma mansoni | importin beta-1 | 0.0058 | 0.0562 | 0.0564 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0109 | 0.011 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0016 | 0.0065 | 0.0089 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0315 | 0.362 | 0.6705 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0065 | 0.0065 |
Mycobacterium ulcerans | hypothetical protein | 0.0072 | 0.0732 | 0.1958 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0013 | 0.0029 | 0.0169 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0043 | 0.0379 | 1 |
Plasmodium vivax | glutathione reductase, putative | 0.0039 | 0.0331 | 0.193 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0072 | 0.0732 | 0.1562 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.026 | 0.2963 | 0.4076 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0039 | 0.0337 | 0.0337 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.003 | 0.0231 | 0.0231 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0216 | 0.2441 | 0.3357 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0072 | 0.0732 | 0.1313 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.2106 | 0.2111 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0072 | 0.0732 | 0.0734 |
Schistosoma mansoni | cpg binding protein | 0.0125 | 0.1353 | 0.1356 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0047 | 0.0431 | 0.0595 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0072 | 0.0732 | 0.1313 |
Entamoeba histolytica | hypothetical protein | 0.0075 | 0.0758 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0029 | 0.0018 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0109 | 0.0233 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0043 | 0.0379 | 0.0521 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0037 | 0.0311 | 0.0664 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0598 | 0.699 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0432 | 0.0594 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.1073 | 0.1476 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0283 | 0.3239 | 0.4634 |
Trichomonas vaginalis | importin beta-1, putative | 0.0047 | 0.0431 | 0.1544 |
Plasmodium falciparum | thioredoxin reductase | 0.0039 | 0.0331 | 0.193 |
Brugia malayi | Pre-SET motif family protein | 0.0216 | 0.2441 | 0.5206 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0013 | 0.0029 | 0.5 |
Echinococcus granulosus | geminin | 0.0188 | 0.2106 | 0.2111 |
Onchocerca volvulus | 0.0245 | 0.2792 | 1 | |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0098 | 0.1041 | 0.1889 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0109 | 0.0392 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0072 | 0.0732 | 0.1313 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0065 | 0.0065 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0283 | 0.3239 | 0.4634 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0109 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0187 | 0.067 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0013 | 0.0029 | 0.0169 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0043 | 0.0379 | 0.221 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0088 | 0.0923 | 0.6189 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.2106 | 0.2111 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0101 | 0.1073 | 0.1076 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.007 | 0.0697 | 0.0697 |
Plasmodium falciparum | glutathione reductase | 0.0039 | 0.0331 | 0.193 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0187 | 0.067 |
Trichomonas vaginalis | ran, putative | 0.0043 | 0.0379 | 0.1358 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0058 | 0.0562 | 0.0562 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0013 | 0.0029 | 0.0104 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.0065 | 0.0138 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0013 | 0.0029 | 0.0169 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.