Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.0463 | 0.0929 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0025 | 0.0341 | 0.0684 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0016 | 0.0184 | 0.0369 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0009 | 0.004 | 0.0081 |
Schistosoma mansoni | hypothetical protein | 0.0056 | 0.0921 | 0.1125 |
Brugia malayi | Smad1 | 0.0009 | 0.0051 | 0.0101 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0012 | 0.015 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0011 | 0.0079 | 0.0079 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0012 | 0.015 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0449 | 0.8191 | 0.8191 |
Schistosoma mansoni | hypothetical protein | 0.0449 | 0.8191 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0184 | 0.0369 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0016 | 0.0184 | 0.0184 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0012 | 0.015 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0023 | 0.0047 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0051 | 0.0062 |
Brugia malayi | Hepatic leukemia factor | 0.0011 | 0.0079 | 0.0159 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0025 | 0.003 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.14 | 1 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0008 | 0.0023 | 0.0023 |
Schistosoma mansoni | transcriptional factor nfil3/e4bp4 | 0.0011 | 0.0079 | 0.0097 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0071 | 0.1189 | 0.1189 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.004 | 0.0081 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0016 | 0.0184 | 0.0184 |
Schistosoma mansoni | smad | 0.0009 | 0.0051 | 0.0062 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0016 | 0.0184 | 0.0369 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.0463 | 0.0929 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.14 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0023 | 0.0047 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0009 | 0.0051 | 0.0101 |
Loa Loa (eye worm) | acetyltransferase | 0.0169 | 0.3006 | 0.603 |
Echinococcus multilocularis | smad | 0.0009 | 0.0051 | 0.0051 |
Schistosoma mansoni | cytochrome P450 | 0.0025 | 0.0341 | 0.0416 |
Loa Loa (eye worm) | cytochrome P450 | 0.0025 | 0.0341 | 0.0684 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0012 | 0.015 |
Schistosoma mansoni | thyroid hormone receptor | 0.0016 | 0.0184 | 0.0225 |
Schistosoma mansoni | Smad4 | 0.0009 | 0.0051 | 0.0062 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0008 | 0.0023 | 0.0028 |
Echinococcus multilocularis | protocadherin 11 | 0.0011 | 0.0079 | 0.0079 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0016 | 0.0184 | 0.0225 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0016 | 0.0184 | 0.0369 |
Brugia malayi | nuclear hormone receptor | 0.0008 | 0.0023 | 0.0047 |
Brugia malayi | nuclear receptor NHR-88 | 0.0008 | 0.0023 | 0.0047 |
Brugia malayi | nuclear hormone receptor | 0.0016 | 0.0184 | 0.0369 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0012 | 0.015 |
Loa Loa (eye worm) | cell death specification protein 2 | 0.0011 | 0.0079 | 0.0159 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0012 | 0.015 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0016 | 0.0184 | 0.0225 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.004 | 0.0081 |
Schistosoma mansoni | nuclear receptor | 0.0008 | 0.0023 | 0.0028 |
Brugia malayi | Cytochrome P450 family protein | 0.0115 | 0.2 | 0.401 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0016 | 0.0184 | 0.0184 |
Schistosoma mansoni | tar DNA-binding protein | 0.0142 | 0.2508 | 0.3061 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0009 | 0.0051 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.004 | 0.0081 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0009 | 0.004 | 0.0049 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0082 | 0.14 | 0.14 |
Brugia malayi | Cytochrome P450 family protein | 0.0025 | 0.0341 | 0.0684 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0025 | 0.0341 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0011 | 0.0079 | 0.0568 |
Echinococcus granulosus | transcriptional factor nfil3:e4bp4 | 0.0011 | 0.0079 | 0.0079 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0016 | 0.0184 | 0.0184 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.14 | 0.1709 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0151 | 0.2679 | 0.2679 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0184 | 0.0369 |
Echinococcus multilocularis | GPCR, family 2 | 0.0071 | 0.1189 | 0.1189 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0016 | 0.0184 | 0.0225 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0067 | 0.1117 | 1 |
Brugia malayi | hypothetical protein | 0.0082 | 0.14 | 0.2809 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0224 | 0.4017 | 0.8056 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0016 | 0.0184 | 0.0369 |
Schistosoma mansoni | hypothetical protein | 0.0153 | 0.2708 | 0.3306 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0016 | 0.0184 | 0.0369 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0011 | 0.0079 | 0.0079 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0012 | 0.015 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0016 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0184 | 0.0369 |
Schistosoma mansoni | thyrotroph embryonic factor related | 0.0011 | 0.0079 | 0.0097 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0025 | 0.0341 | 0.5 |
Onchocerca volvulus | 0.0056 | 0.0921 | 0.9731 | |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0016 | 0.0184 | 0.0184 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0016 | 0.0184 | 0.0369 |
Onchocerca volvulus | 0.0016 | 0.0184 | 0.1943 | |
Loa Loa (eye worm) | RNA binding protein | 0.0142 | 0.2508 | 0.5029 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0051 | 0.0062 |
Schistosoma mansoni | par domain protein | 0.0011 | 0.0079 | 0.0097 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0079 | 0.0159 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0016 | 0.0184 | 0.0225 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0016 | 0.0184 | 0.0369 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0008 | 0.0023 | 0.0047 |
Schistosoma mansoni | thyroid hormone receptor | 0.0016 | 0.0184 | 0.0225 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0012 | 0.015 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0016 | 0.0184 | 0.0184 |
Echinococcus multilocularis | 0.0025 | 0.0341 | 0.0341 | |
Echinococcus multilocularis | ccaat enhancer binding protein delta ccaat enhancer binding protein beta | 0.0011 | 0.0079 | 0.0079 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0008 | 0.0023 | 0.0023 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0008 | 0.0023 | 0.0028 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0079 | 0.0159 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0025 | 0.0341 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0947 | 0.1899 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0008 | 0.0023 | 0.0245 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0151 | 0.2679 | 0.2679 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0025 | 0.0025 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0115 | 0.2 | 0.401 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0009 | 0.004 | 0.0081 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0016 | 0.0184 | 0.0225 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0008 | 0.0023 | 0.0047 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.005 | 0.0799 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0071 | 0.1189 | 0.2384 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0016 | 0.0184 | 0.0225 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.1189 | 0.1451 |
Brugia malayi | RNA binding protein | 0.0142 | 0.2508 | 0.5029 |
Brugia malayi | Cell death specification protein 2 | 0.0011 | 0.0079 | 0.0159 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0025 | 0.0341 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0016 | 0.0184 | 0.0369 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0151 | 0.2679 | 0.3271 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0016 | 0.0184 | 0.0225 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0071 | 0.1189 | 0.1189 |
Brugia malayi | Cytochrome P450 family protein | 0.0025 | 0.0341 | 0.0684 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0547 | 1 | 1 |
Brugia malayi | Cell death specification protein 2 | 0.0011 | 0.0079 | 0.0159 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0016 | 0.0184 | 0.0369 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0046 | 0.0723 | 0.5 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0025 | 0.0341 | 0.0684 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0079 | 0.0159 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0008 | 0.0023 | 0.0028 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0011 | 0.0079 | 0.0079 |
Schistosoma mansoni | survival motor neuron protein | 0.0056 | 0.0921 | 0.1125 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0016 | 0.0184 | 0.0369 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0009 | 0.004 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0079 | 0.0159 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0012 | 0.015 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0016 | 0.0184 | 0.0369 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0023 | 0.0047 |
Schistosoma mansoni | nuclear hormone receptor | 0.0008 | 0.0023 | 0.0028 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.005 | 0.0799 | 0.0799 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0497 | 0.0606 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0082 | 0.14 | 0.14 |
Echinococcus multilocularis | cyclic AMP responsive element binding protein | 0.0011 | 0.0079 | 0.0079 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0016 | 0.0184 | 0.1943 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0008 | 0.0023 | 0.0245 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0009 | 0.0051 | 0.0062 |
Schistosoma mansoni | nuclear receptor | 0.0008 | 0.0023 | 0.0028 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0016 | 0.0184 | 0.0369 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0153 | 0.2708 | 0.5431 |
Brugia malayi | bZIP transcription factor family protein | 0.0011 | 0.0079 | 0.0159 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0023 | 0.0047 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0008 | 0.0023 | 0.0023 |
Echinococcus multilocularis | tar DNA binding protein | 0.0142 | 0.2508 | 0.2508 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0046 | 0.0723 | 1 |
Echinococcus granulosus | protocadherin 11 | 0.0011 | 0.0079 | 0.0079 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0016 | 0.0184 | 0.0184 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.005 | 0.0799 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.2708 | 0.5431 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0082 | 0.14 | 0.1709 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0008 | 0.0023 | 0.0047 |
Brugia malayi | MH2 domain containing protein | 0.0136 | 0.2387 | 0.4787 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0184 | 0.0369 |
Brugia malayi | Cytochrome P450 family protein | 0.0025 | 0.0341 | 0.0684 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0058 | 0.0947 | 0.1156 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0016 | 0.0184 | 0.0369 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0025 | 0.0341 | 0.0341 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.14 | 1 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0276 | 0.4986 | 0.4986 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0016 | 0.0184 | 0.0184 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0012 | 0.015 |
Loa Loa (eye worm) | Smad1 | 0.0009 | 0.0051 | 0.0101 |
Echinococcus multilocularis | protocadherin 11 | 0.0011 | 0.0079 | 0.0079 |
Onchocerca volvulus | 0.0011 | 0.0079 | 0.084 | |
Brugia malayi | Cell death specification protein 2 | 0.0011 | 0.0079 | 0.0159 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0079 | 0.0159 |
Brugia malayi | steroid hormone receptor | 0.0016 | 0.0184 | 0.0369 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0151 | 0.2679 | 0.2679 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0184 | 0.0369 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0136 | 0.2387 | 0.4787 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0051 | 0.0101 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0008 | 0.0023 | 0.0023 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0016 | 0.0184 | 0.0369 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0008 | 0.0023 | 0.0047 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0169 | 0.3006 | 0.367 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0079 | 0.0159 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0023 | 0.0047 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0169 | 0.3006 | 0.603 |
Brugia malayi | nuclear receptor NHR-67 | 0.0008 | 0.0023 | 0.0047 |
Schistosoma mansoni | nuclear hormone receptor | 0.0016 | 0.0184 | 0.0225 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0025 | 0.0341 | 0.5 |
Onchocerca volvulus | 0.0011 | 0.0079 | 0.084 | |
Brugia malayi | Latrophilin receptor protein 2 | 0.0071 | 0.1189 | 0.2384 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0463 | 0.0566 |
Echinococcus granulosus | FTZ F1 alpha | 0.0016 | 0.0184 | 0.0184 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0016 | 0.0184 | 0.0184 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0008 | 0.0023 | 0.0047 |
Echinococcus multilocularis | tumor protein p63 | 0.0394 | 0.7169 | 0.7169 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0051 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0023 | 0.0047 |
Echinococcus granulosus | X box binding protein 1 | 0.0341 | 0.6185 | 0.6185 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0067 | 0.1117 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.004 | 0.0081 |
Onchocerca volvulus | 0.0058 | 0.0947 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0341 | 0.6185 | 0.7551 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0008 | 0.0023 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0184 | 0.0369 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0009 | 0.004 | 0.0049 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0016 | 0.0184 | 0.0369 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.005 | 0.0799 | 0.6355 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0009 | 0.004 | 0.004 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0071 | 0.1189 | 0.1189 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0079 | 0.0097 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0012 | 0.015 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0012 | 0.015 |
Echinococcus granulosus | tar DNA binding protein | 0.0142 | 0.2508 | 0.2508 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0169 | 0.3006 | 0.3006 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0009 | 0.0051 | 0.0051 |
Schistosoma mansoni | zinc finger protein | 0.0008 | 0.0023 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0023 | 0.0047 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.006 | 0.006 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0151 | 0.2679 | 0.5374 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0164 | 0.2919 | 0.2919 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0016 | 0.0184 | 0.0369 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0016 | 0.0184 | 0.0369 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0011 | 0.0079 | 0.0079 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0071 | 0.1189 | 0.1189 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.004 | 0.0081 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.0497 | 0.0497 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0016 | 0.0184 | 0.0184 |
Schistosoma mansoni | coup transcription factor | 0.0016 | 0.0184 | 0.0225 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0067 | 0.1117 | 0.2241 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0023 | 0.0047 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0136 | 0.2387 | 0.4787 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0025 | 0.0341 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0142 | 0.2508 | 0.5029 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0008 | 0.0023 | 0.0047 |
Echinococcus granulosus | dnaJ subfamily B | 0.0449 | 0.8191 | 0.8191 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0008 | 0.0023 | 0.0047 |
Onchocerca volvulus | 0.0011 | 0.0079 | 0.084 | |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.4986 | 1 |
Loa Loa (eye worm) | DR-78 | 0.0008 | 0.0023 | 0.0047 |
Echinococcus multilocularis | Smad4 | 0.0009 | 0.0051 | 0.0051 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0276 | 0.4986 | 0.4986 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.1189 | 0.1451 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0025 | 0.0341 | 0.0684 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0224 | 0.4017 | 0.8056 |
Onchocerca volvulus | 0.0011 | 0.0079 | 0.084 | |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0067 | 0.1117 | 0.1117 |
Echinococcus multilocularis | X box binding protein 1 | 0.0341 | 0.6185 | 0.6185 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0151 | 0.2679 | 0.5374 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0067 | 0.1117 | 0.1364 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0547 | 1 | 1 |
Echinococcus granulosus | protocadherin 11 | 0.0011 | 0.0079 | 0.0079 |
Schistosoma mansoni | tar DNA-binding protein | 0.0142 | 0.2508 | 0.3061 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1189 | 0.2384 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0067 | 0.1117 | 0.1117 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0151 | 0.2679 | 0.3271 |
Trypanosoma brucei | cytochrome P450, putative | 0.0025 | 0.0341 | 0.5 |
Echinococcus granulosus | ccaat enhancer binding protein delta | 0.0011 | 0.0079 | 0.0079 |
Brugia malayi | tailless protein | 0.0008 | 0.0023 | 0.0047 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0142 | 0.2508 | 0.5029 |
Brugia malayi | nuclear receptor RXR | 0.0008 | 0.0023 | 0.0047 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0016 | 0.0184 | 0.0369 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0008 | 0.0023 | 0.0023 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.1189 | 0.1451 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0008 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0079 | 0.0159 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0079 | 0.0159 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0058 | 0.0116 |
Brugia malayi | hypothetical protein | 0.0276 | 0.4986 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0071 | 0.1189 | 0.1189 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0016 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0016 | 0.0184 | 0.0369 |
Brugia malayi | TAR-binding protein | 0.0142 | 0.2508 | 0.5029 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0025 | 0.0025 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0008 | 0.0023 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0079 | 0.0159 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0012 | 0.015 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0008 | 0.0023 | 0.0023 |
Brugia malayi | ecdysone receptor | 0.0008 | 0.0023 | 0.0047 |
Loa Loa (eye worm) | TAR-binding protein | 0.0142 | 0.2508 | 0.5029 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0016 | 0.0184 | 0.0369 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0008 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0184 | 0.0369 |
Onchocerca volvulus | 0.0008 | 0.0023 | 0.0245 | |
Loa Loa (eye worm) | bZIP transcription factor family protein | 0.0011 | 0.0079 | 0.0159 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0009 | 0.0051 | 0.0051 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0016 | 0.0184 | 0.1943 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.14 | 1 |
Echinococcus granulosus | smad | 0.0009 | 0.0051 | 0.0051 |
Echinococcus granulosus | tumor protein p63 | 0.0394 | 0.7169 | 0.7169 |
Brugia malayi | cytochrome P450 | 0.0025 | 0.0341 | 0.0684 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.006 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0023 | 0.0047 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0016 | 0.0184 | 0.0369 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0497 | 0.0606 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0016 | 0.0184 | 0.0184 |
Echinococcus granulosus | Smad4 | 0.0009 | 0.0051 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0023 | 0.0047 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0016 | 0.0184 | 0.0184 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0079 | 0.0097 |
Schistosoma mansoni | tar DNA-binding protein | 0.0142 | 0.2508 | 0.3061 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0009 | 0.0051 | 0.0051 |
Brugia malayi | nuclear receptor NHR-88 | 0.0016 | 0.0184 | 0.0369 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.006 | 0.006 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0064 | 0.1062 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0009 | 0.0051 | 0.0101 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0016 | 0.0184 | 0.0369 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.4017 | 0.8056 |
Brugia malayi | hypothetical protein | 0.0009 | 0.004 | 0.0081 |
Brugia malayi | hypothetical protein | 0.0009 | 0.004 | 0.0081 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0224 | 0.4017 | 0.8056 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0023 | 0.0047 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0012 | 0.015 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0051 | 0.0101 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0067 | 0.1117 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0016 | 0.0184 | 0.0184 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0008 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0062 | 0.1034 | 0.2074 |
Onchocerca volvulus | 0.0032 | 0.0463 | 0.4894 | |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0056 | 0.0921 | 0.1848 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0051 | 0.0101 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.005 | 0.0799 | 1 |
Onchocerca volvulus | 0.0008 | 0.0023 | 0.0245 | |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0046 | 0.0723 | 0.5161 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.0497 | 0.0497 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.1189 | 0.1451 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0067 | 0.1118 | 0.1364 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0009 | 0.004 | 0.0081 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0012 | 0.015 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0547 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0016 | 0.0184 | 0.0369 |
Mycobacterium leprae | putative cytochrome p450 | 0.0025 | 0.0341 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0142 | 0.2508 | 0.3061 |
Echinococcus multilocularis | transcriptional factor nfil3:e4bp4 | 0.0011 | 0.0079 | 0.0079 |
Brugia malayi | hypothetical protein | 0.0008 | 0.0023 | 0.0047 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0016 | 0.0184 | 0.1943 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0016 | 0.0184 | 0.0225 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0071 | 0.1189 | 0.2384 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0025 | 0.0025 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0016 | 0.0184 | 0.0225 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0067 | 0.1117 | 1 |
Brugia malayi | hypothetical protein | 0.0008 | 0.0023 | 0.0047 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0012 | 0.015 |
Schistosoma mansoni | tar DNA-binding protein | 0.0142 | 0.2508 | 0.3061 |
Brugia malayi | nuclear receptor RXR | 0.0009 | 0.004 | 0.0081 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.005 | 0.0799 | 0.6355 |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0341 | 0.0416 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0012 | 0.015 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0012 | 0.015 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0023 | 0.0047 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0025 | 0.0025 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0151 | 0.2679 | 0.3271 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0184 | 0.0369 |
Brugia malayi | conserved hypotetical protein | 0.0008 | 0.0023 | 0.0047 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0016 | 0.0184 | 0.0184 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0051 | 0.0062 |
Schistosoma mansoni | nuclear hormone receptor | 0.0008 | 0.0023 | 0.0028 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0151 | 0.2679 | 0.2679 |
Brugia malayi | ecdysteroid receptor | 0.0016 | 0.0184 | 0.0369 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0008 | 0.0023 | 0.0023 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0016 | 0.0184 | 0.0184 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0008 | 0.0023 | 0.0023 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0008 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0023 | 0.0047 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0025 | 0.0341 | 0.5 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0016 | 0.0184 | 0.0369 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.