Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | tar DNA binding protein | 0.0073 | 0.1241 | 0.0807 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.1241 | 0.0807 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.1241 | 0.0807 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0164 | 0.428 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0335 | 1 | 1 |
Mycobacterium ulcerans | glucose-6-phosphate 1-dehydrogenase | 0.0107 | 0.2386 | 0.3964 |
Mycobacterium ulcerans | glucose-6-phosphate 1-dehydrogenase | 0.007 | 0.1148 | 0.0022 |
Loa Loa (eye worm) | glucose-6-phosphate dehydrogenase | 0.0107 | 0.2386 | 1 |
Trypanosoma cruzi | glucose-6-phosphate 1-dehydrogenase, putative | 0.0107 | 0.2386 | 1 |
Echinococcus multilocularis | glucose 6 phosphate 1 dehydrogenase | 0.0107 | 0.2386 | 1 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0335 | 1 | 1 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0335 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0335 | 1 | 1 |
Toxoplasma gondii | glucose-6-phosphate 1-dehydrogenase | 0.007 | 0.1148 | 0.0045 |
Chlamydia trachomatis | glucose-6-phosphate 1-dehydrogenase | 0.0107 | 0.2386 | 0.5 |
Trypanosoma brucei | glucose-6-phosphate 1-dehydrogenase | 0.0107 | 0.2386 | 0.5 |
Toxoplasma gondii | glucose-6-phosphate 1-dehydrogenase | 0.0116 | 0.2703 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.007 | 0.1141 | 0.2569 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0164 | 0.428 | 1 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0335 | 1 | 0.5 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0164 | 0.428 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.1241 | 0.0807 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0335 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0335 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0335 | 1 | 1 |
Brugia malayi | glucose-6-phosphate dehydrogenase | 0.0107 | 0.2386 | 1 |
Leishmania major | glucose-6-phosphate 1-dehydrogenase, putative | 0.0107 | 0.2386 | 1 |
Schistosoma mansoni | glucose-6-phosphate 1-dehydrogenase | 0.0107 | 0.2386 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0335 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.1241 | 0.0807 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0335 | 1 | 1 |
Echinococcus granulosus | glucose 6 phosphate 1 dehydrogenase | 0.0107 | 0.2386 | 1 |
Plasmodium falciparum | glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | 0.0116 | 0.2703 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.1241 | 0.0807 |
Echinococcus granulosus | tar DNA binding protein | 0.0073 | 0.1241 | 0.0807 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0335 | 1 | 1 |
Plasmodium vivax | glucose-6-phosphate 1-dehydrogenase, putative | 0.0116 | 0.2703 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.